Secondary Analyses of Existing Alcohol Epidemiology Data (R01) | Apply Online

Opportunity Summary:

The grant opportunity titled "Secondary Analyses of Existing Alcohol Epidemiology Data (R01)" (Funding Opportunity Number PAR-14-338) is a National Institutes of Health (NIH) research grant designed to fund investigator-initiated projects that reanalyze data that already exist, rather than collecting new primary data. The core purpose is to use established, currently available epidemiologic datasets to sharpen what is known about alcohol consumption patterns and the public health burden of alcohol-related problems. In practical terms, the FOA is aimed at researchers who can ask important new questions, test new hypotheses, or apply improved analytic approaches using data that have already been collected through surveys, cohorts, surveillance systems, administrative records, or other large epidemiologic sources.

A central theme of the announcement is strengthening knowledge about the incidence and prevalence of alcohol-related problems and disorders, along with their etiology in the general population. That includes work that clarifies how alcohol use and alcohol-related harms emerge, change over time, and differ across groups, settings, and life stages. The FOA also highlights interest in identifying and characterizing risk and protective factors, meaning it welcomes studies that investigate what increases vulnerability (for example, comorbid mental health conditions, social stressors, or environmental exposure) as well as what reduces risk (for example, supportive social networks, policy protections, or other resilience-related factors). Because the scope is epidemiologic, the emphasis is on population-level patterns and determinants rather than small clinical samples, and the expectation is that secondary analyses will yield findings that can inform prevention, intervention targeting, and public health planning.

Beyond substantive questions, the opportunity explicitly values analytic work that demonstrates or advances methodology in alcohol epidemiology. This can include sophisticated statistical modeling, novel ways of harmonizing or integrating multiple datasets, methods for handling missing data or measurement differences, stronger causal inference approaches, improved longitudinal modeling, or techniques that help address bias and confounding in observational data. In other words, the FOA is not limited to descriptive analyses; it also encourages applicants to push the field forward by using or developing analytic strategies that make epidemiologic findings on alcohol use more reliable, interpretable, and actionable.

This is an R01 mechanism, meaning it supports full research projects with the typical NIH expectation of a clearly articulated scientific premise, rigorous analytic plan, and strong potential for meaningful impact. The funding instrument type is a grant, the activity category is health, and the CFDA listing provided is 93.273 (Alcohol Research Programs). The announcement states there is no cost sharing or matching requirement, which generally means applicants are not required to provide non-federal funds as a condition of receiving the award.

Eligibility is broad and includes many types of domestic U.S. organizations, such as public and private institutions of higher education, state and local governments (including counties, cities, townships, special district governments), independent school districts, and a range of nonprofit organizations (both 501(c)(3) and non-501(c)(3)). It also extends to tribal governments and tribal organizations, public housing authorities/Indian housing authorities, and for-profit organizations other than small businesses, as well as small businesses. The FOA further clarifies eligibility for a variety of institution types commonly referenced in federal funding, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs). Faith-based and community-based organizations are also included. Importantly, the opportunity allows non-U.S. entities (foreign organizations and foreign institutions) to apply, and it allows non-domestic components of U.S. organizations to participate; foreign components are permitted under NIH policy as defined in the NIH Grants Policy Statement.

In terms of timing and administrative details, the FOA was posted and created on September 9, 2014, with an original and final closing date of September 7, 2017, and an archive date of October 8, 2017, indicating the announcement is no longer active as a current solicitation but remains available for reference. The NIH provides an additional information link to the full announcement text on the NIH grants site (http://grants.nih.gov/grants/guide/pa-files/PAR-14-338.html). For access or technical issues, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV, specifically for problems accessing the announcement electronically or linking to it.

Overall, PAR-14-338 is best understood as an NIH-funded pathway for researchers to extract new public health value from existing alcohol epidemiology data by answering high-priority questions about alcohol use and alcohol-related harms, identifying determinants and protective factors, and strengthening the analytic toolbox used to study alcohol-related outcomes at the population level.

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