Opportunity Information: Apply for PA 14 336

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Secondary Analyses of Existing Alcohol Epidemiology Data (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs.
  • This funding opportunity was created on Sep 9, 2014 and posted on Sep 9, 2014.
  • Applicants must submit their applications by Sep 7, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $275,000.00 in funding.
  • Eligible applicants include: For profit organizations other than small businesses Public housing authorities/Indian housing authorities State governments County governments Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments Private institutions of higher education Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Independent school districts Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The NIH grant opportunity "Secondary Analyses of Existing Alcohol Epidemiology Data (R21)" (Funding Opportunity Number PA-14-336) was designed to fund investigator-initiated projects that reanalyze data that already exist, rather than collecting new data. The central purpose is to use established alcohol-related epidemiology datasets to deepen what is known about how people drink, how alcohol-related problems emerge and persist in communities, and which factors increase risk or provide protection across different populations. Because it uses the R21 mechanism, the emphasis is generally on exploratory, developmental, or proof-of-concept work that can generate strong preliminary findings, refine hypotheses, or demonstrate the value of new analytic approaches.

At the topic level, the FOA prioritizes research that improves understanding of the incidence and prevalence of alcohol-related problems and disorders, along with their etiology, meaning the pathways and contributing causes behind the development of alcohol misuse and alcohol use disorders. Projects are expected to make meaningful use of existing datasets to answer questions that could shift or sharpen how the field understands alcohol consumption patterns and alcohol-related harm in the population. In practical terms, that can include studying differences by age group, sex, race and ethnicity, geography, or other demographic and social determinants; examining comorbidity with mental health or other substance use; or identifying risk and protective factors that explain why some people or groups experience greater harm at similar levels of consumption.

A notable feature of the announcement is that it explicitly welcomes studies that push methodology forward. Beyond simply applying standard statistical approaches, the FOA highlights interest in analytic techniques that demonstrate or promote methodological advances in alcohol epidemiology research. That can include improved measurement strategies, better handling of missing or biased data, innovative modeling of trajectories over time, causal inference methods, approaches that leverage complex survey designs, or other advanced epidemiologic and biostatistical methods that strengthen the reliability and interpretability of results drawn from existing data resources.

From an administrative and eligibility standpoint, this was a discretionary NIH grant program under the health funding activity category, listed under CFDA number 93.273 (Alcohol Research Programs). The award ceiling was set at $275,000, and there was no cost sharing or matching requirement. Eligibility was broad and included many types of U.S. and non-U.S. organizations. Eligible applicants included for-profit organizations (other than small businesses) and small businesses; nonprofit organizations (including those with and without 501(c)(3) status); public and private institutions of higher education; and multiple levels of government such as state, county, city or township, special district governments, independent school districts, and public housing authorities/Indian housing authorities. The FOA also explicitly listed a wide range of institution types and community-serving organizations as eligible, including HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, AANAPISI institutions, tribal colleges and universities, tribally controlled colleges and universities, faith-based or community-based organizations, regional organizations, and eligible federal agencies.

International participation was allowed. Non-U.S. entities (foreign organizations and foreign institutions) could apply, non-U.S. components of U.S. organizations were eligible, and foreign components as defined in the NIH Grants Policy Statement were permitted. This makes the opportunity relevant to investigators working with internationally collected alcohol epidemiology datasets or cross-national comparative data, as long as the proposed work fits the FOA focus on secondary analysis and alcohol epidemiology.

In terms of timing and status, the FOA was posted and created on September 9, 2014, with an original and current closing date listed as September 7, 2017, and an archive date of October 8, 2017. That means this particular announcement is no longer active for new submissions, but it remains a useful reference point for understanding NIH priorities around secondary analysis in alcohol epidemiology and for locating related, newer NIH opportunities with similar goals. The full announcement was linked through the NIH Grants Guide, and contact information was provided through the NIH Office of Extramural Research (OER) webmaster channels for access or technical issues related to the posting.

FAQs: Secondary Analyses of Existing Alcohol Epidemiology Data (R21) (PA-14-336)

What is the NIH funding opportunity PA-14-336?

PA-14-336 is an NIH grant opportunity titled "Secondary Analyses of Existing Alcohol Epidemiology Data (R21)." It was designed to support investigator-initiated projects that reanalyze existing alcohol-related epidemiology datasets rather than collecting new data.

What is the main purpose of this FOA?

The central purpose is to use established alcohol epidemiology datasets to deepen understanding of how people drink, how alcohol-related problems emerge and persist in communities, and which factors increase risk or provide protection across different populations.

Does this opportunity fund new data collection?

No. The FOA emphasizes secondary analyses of data that already exist, not the collection of new data.

What does the R21 mechanism imply about the type of research expected?

Because it uses the R21 mechanism, the emphasis is generally on exploratory, developmental, or proof-of-concept work. Projects are expected to generate strong preliminary findings, refine hypotheses, or demonstrate the value of new analytic approaches using existing datasets.

What research topics were prioritized in this announcement?

The FOA prioritized research that improves understanding of the incidence and prevalence of alcohol-related problems and disorders, as well as their etiology (the pathways and contributing causes behind the development of alcohol misuse and alcohol use disorders).

What kinds of questions could be addressed using existing datasets under this FOA?

Projects could use existing datasets to answer questions that sharpen how the field understands alcohol consumption patterns and alcohol-related harm at the population level. Examples mentioned include studying differences by age group, sex, race and ethnicity, geography, and other demographic or social determinants.

Could projects examine comorbid conditions or other substance use?

Yes. The FOA noted that work could examine comorbidity with mental health conditions or other substance use as part of understanding alcohol-related problems and risk.

Was identifying risk and protective factors within scope?

Yes. The FOA highlighted interest in identifying risk and protective factors that help explain why some people or groups experience greater harm at similar levels of alcohol consumption.

How important were methodological or analytic advances to this FOA?

Methodological innovation was explicitly welcomed. Beyond standard statistical approaches, the FOA highlighted interest in analytic techniques that demonstrate or promote methodological advances in alcohol epidemiology research.

What types of methodological approaches were highlighted as examples?

Examples included improved measurement strategies, better handling of missing or biased data, innovative modeling of trajectories over time, causal inference methods, approaches that leverage complex survey designs, and other advanced epidemiologic and biostatistical methods that strengthen the reliability and interpretability of results from existing data resources.

What is the CFDA number associated with this opportunity?

The opportunity was listed under CFDA number 93.273, Alcohol Research Programs.

What was the award ceiling for PA-14-336?

The award ceiling was set at $275,000.

Was cost sharing or matching required?

No. The FOA specified that there was no cost sharing or matching requirement.

What types of organizations were eligible to apply?

Eligibility was broad and included many types of U.S. and non-U.S. organizations. Eligible applicants included for-profit organizations (other than small businesses) and small businesses; nonprofit organizations (including those with and without 501(c)(3) status); public and private institutions of higher education; and multiple levels of government.

Which government entities were included as eligible applicants?

The FOA listed multiple levels of government as eligible, including state, county, city or township, special district governments, independent school districts, and public housing authorities/Indian housing authorities.

Were minority-serving institutions and community-based organizations explicitly included?

Yes. The FOA explicitly listed many institution types and community-serving organizations as eligible, including HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, AANAPISI institutions, tribal colleges and universities, tribally controlled colleges and universities, faith-based or community-based organizations, and regional organizations.

Could eligible federal agencies apply?

Yes. Eligible federal agencies were included in the FOA's eligibility list.

Was international participation allowed?

Yes. International participation was allowed. Non-U.S. entities (foreign organizations and foreign institutions) could apply, non-U.S. components of U.S. organizations were eligible, and foreign components (as defined in the NIH Grants Policy Statement) were permitted.

Does this FOA support analyses of internationally collected or cross-national datasets?

It can, based on the allowance for international participation. The FOA was relevant to investigators working with internationally collected alcohol epidemiology datasets or cross-national comparative data, as long as the work fit the FOA focus on secondary analysis and alcohol epidemiology.

When was this FOA posted and created?

The FOA was posted and created on September 9, 2014.

What were the closing date and archive date for this opportunity?

The original and current closing date was listed as September 7, 2017, and the archive date was October 8, 2017.

Is PA-14-336 still active for new submissions?

No. Based on the closing and archive dates provided, this particular announcement is no longer active for new submissions.

Why might this archived FOA still be useful?

Even though it is no longer active, it can still serve as a reference for understanding NIH priorities around secondary analysis in alcohol epidemiology and for locating related, newer NIH opportunities with similar goals.

Where was the full announcement made available?

The full announcement was linked through the NIH Grants Guide.

Who was listed for contact or technical issues related to the posting?

Contact information was provided through the NIH Office of Extramural Research (OER) webmaster channels for access or technical issues related to the posting.

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