Opportunity Information: Apply for PA 13 168
Apply for PA 13 168
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Secondary Analyses of Existing Data Sets and Stored Biospecimens to Address Clinical Aging Research Questions (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866 Aging Research.
- This funding opportunity was created on Mar 29, 2013 and posted on Mar 29, 2013.
- Applicants must submit their applications by May 7, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Native American tribal governments (Federally recognized) State governments Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments County governments Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts Special district governments For profit organizations other than small businesses Public housing authorities/Indian housing authorities.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NIH grant opportunity PA 13-168, titled "Secondary Analyses of Existing Data Sets and Stored Biospecimens to Address Clinical Aging Research Questions (R01)," supports research that reuses already collected human data and/or stored biological samples to answer clinically meaningful questions about aging. Instead of funding new participant recruitment or new large-scale data collection, this FOA is geared toward investigators who can take advantage of existing resources, such as established cohort studies, clinical trial data sets, health records-based repositories, registries, or biobanks with stored specimens, and use them to test specific, well-defined hypotheses relevant to aging and older adults.
The scientific focus is clinical aging research across the life span, with an emphasis on how age-related changes influence health, and on diseases and disabilities that disproportionately affect older persons. In practice, this can include questions about the development and progression of chronic conditions, geriatric syndromes, functional decline, disability, resilience, multimorbidity, and other factors that shape health and independence in later life. The FOA is also intended to support work that can directly inform geriatric practice, including approaches to maintaining health, managing disease, and preventing disability among older adults.
A key goal of the program is to fund projects where secondary analyses can either (1) address concrete hypotheses in clinical aging research, or (2) generate evidence that helps shape the design and implementation of future studies, including epidemiologic studies or human intervention trials. In other words, the expectation is that the reuse of existing data or biospecimens should produce actionable insights: results that clarify clinical aging mechanisms, improve risk prediction, identify potentially modifiable factors, refine outcomes or endpoints, or guide the next generation of studies and interventions. The FOA also explicitly allows the use of existing data sets to develop and test new statistical or analytic methods, as long as those methods are meaningfully tied to clinical aging research questions rather than being purely methodological exercises.
Budgeting under this opportunity can include costs related to archiving data for public availability, but only when those archiving activities are directly connected to the proposed secondary analyses. This signals an interest in responsible data stewardship and broader reuse, while still keeping the main emphasis on hypothesis-driven analyses of existing resources rather than building entirely new infrastructure.
Mechanistically, this is an NIH discretionary grant opportunity using the R01 research project grant mechanism, listed under CFDA 93.866 (Aging Research). It does not require cost sharing or matching. The opportunity was posted and created on March 29, 2013, with an original and final closing date of May 7, 2016, and an archive date of June 7, 2016, meaning it is no longer open but remains a useful reference point for similar NIH funding priorities and program structures.
Eligibility is broad and includes a wide range of applicant organizations. Eligible applicants include federal, state, county, city or township governments; special district governments; independent school districts; public and private institutions of higher education; nonprofits with and without 501(c)(3) status; small businesses and other for-profit organizations (with the exception that the listing distinguishes small businesses specifically); public housing authorities/Indian housing authorities; and Native American tribal governments and tribal organizations (including those other than federally recognized entities). The FOA also explicitly includes many institution types and community-based entities often highlighted in federal funding, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American and Native American Pacific Islander Serving Institutions (AANAPISIs), and faith-based or community-based organizations. Importantly, foreign organizations and foreign institutions are eligible to apply, foreign components of U.S. organizations are allowed, and NIH-defined foreign components are permitted, reflecting NIH's willingness to support internationally based work when it advances the goals of clinical aging research.
The sponsoring agency is the National Institutes of Health, and the full announcement was provided through the NIH grants guide at http://grants.nih.gov/grants/guide/pa-files/PA-13-168.html. For technical issues accessing or linking to the announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
FAQs: NIH PA-13-168 (R01) - Secondary Analyses of Existing Data Sets and Stored Biospecimens to Address Clinical Aging Research Questions
What is NIH PA-13-168?
PA-13-168 is an NIH grant opportunity titled "Secondary Analyses of Existing Data Sets and Stored Biospecimens to Address Clinical Aging Research Questions (R01)." It supports research that reuses already collected human data and/or stored biospecimens to answer clinically meaningful questions about aging.
What is the main purpose of this funding opportunity?
The main purpose is to fund hypothesis-driven secondary analyses of existing datasets and/or stored biospecimens that can generate actionable insights in clinical aging research, particularly insights that can inform geriatric practice or shape future research studies.
What does "secondary analyses" mean in the context of this FOA?
In this FOA, "secondary analyses" refers to analyzing data or specimens that have already been collected (for example, data from cohort studies, clinical trials, registries, repositories, or biobanks) rather than collecting new data through new participant recruitment or new large-scale data collection.
Does this opportunity fund new participant recruitment or new large-scale data collection?
No. The FOA is geared toward leveraging existing resources instead of funding new participant recruitment or new large-scale data collection.
What types of existing resources can be used?
Examples mentioned include established cohort studies, clinical trial datasets, health records-based repositories, registries, and biobanks with stored specimens, as well as other already collected human datasets or stored biospecimens appropriate for clinical aging research questions.
What research areas does the FOA emphasize?
The scientific focus is clinical aging research across the life span, emphasizing how age-related changes influence health and focusing on diseases and disabilities that disproportionately affect older persons.
What kinds of aging-related topics are explicitly within scope?
Within-scope topics can include the development and progression of chronic conditions, geriatric syndromes, functional decline, disability, resilience, multimorbidity, and other factors that shape health and independence in later life.
Is the FOA intended to inform clinical practice?
Yes. The FOA is intended to support work that can directly inform geriatric practice, including approaches to maintaining health, managing disease, and preventing disability among older adults.
What outcomes or impacts are expected from funded secondary analyses?
The expectation is that reusing existing data or biospecimens will produce actionable insights, such as clarifying clinical aging mechanisms, improving risk prediction, identifying potentially modifiable factors, refining outcomes or endpoints, or guiding the next generation of studies and interventions.
Can projects be exploratory, or do they need specific hypotheses?
The FOA emphasizes testing specific, well-defined hypotheses relevant to aging and older adults. It also supports secondary analyses that generate evidence to shape the design and implementation of future studies, including epidemiologic studies or human intervention trials.
Does the FOA allow development of new statistical or analytic methods?
Yes. The FOA explicitly allows using existing datasets to develop and test new statistical or analytic methods, as long as the methods are meaningfully tied to clinical aging research questions and are not purely methodological exercises.
Can the budget include costs for archiving data for public availability?
Yes, budgeting can include costs related to archiving data for public availability, but only when those archiving activities are directly connected to the proposed secondary analyses.
What grant mechanism is used for this opportunity?
This opportunity uses the NIH R01 research project grant mechanism.
What is the CFDA number associated with this opportunity?
The opportunity is listed under CFDA 93.866 (Aging Research).
Is cost sharing or matching required?
No. The opportunity does not require cost sharing or matching.
When was PA-13-168 posted and when did it close?
It was posted and created on March 29, 2013. The original and final closing date was May 7, 2016, and the archive date was June 7, 2016.
Is this funding opportunity currently open?
No. Based on the closing and archive dates provided, it is no longer open, though it remains a useful reference point for similar NIH funding priorities and program structures.
Who is eligible to apply?
Eligibility is broad and includes many types of organizations, such as federal, state, county, city or township governments; special district governments; independent school districts; public and private institutions of higher education; nonprofits with and without 501(c)(3) status; small businesses and other for-profit organizations; public housing authorities/Indian housing authorities; and Native American tribal governments and tribal organizations (including those other than federally recognized entities).
Are minority-serving institutions and community-based entities included as eligible applicants?
Yes. The FOA explicitly includes institution types and community-based entities such as HBCUs, Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American and Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based and community-based organizations.
Are foreign organizations eligible?
Yes. Foreign organizations and foreign institutions are eligible to apply. Foreign components of U.S. organizations are allowed, and NIH-defined foreign components are permitted.
Which agency sponsors this opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
Where can the full announcement be found?
The full announcement was provided through the NIH grants guide at http://grants.nih.gov/grants/guide/pa-files/PA-13-168.html.
Who is the contact for technical issues accessing or linking to the announcement?
The contact listed for technical issues is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
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