Opportunity Information: Apply for RFA HD 16 001
Apply for RFA HD 16 001
- The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Secondary Analysis of Existing Databases in Traumatic Brain Injury to Explore Outcomes Relevant to Medical Rehabilitation (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Jul 7, 2015 and posted on Jul 7, 2015.
- Applicants must submit their applications by Oct 30, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,500,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: County governments Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education City or township governments Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education For profit organizations other than small businesses Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Special district governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The NIH funding opportunity titled "Secondary Analysis of Existing Databases in Traumatic Brain Injury to Explore Outcomes Relevant to Medical Rehabilitation (R21)" (Funding Opportunity Number RFA-HD-16-001) was designed to fund research projects that re-use and re-analyze data that already exist, rather than collecting new primary data. The central goal is to generate new insights in traumatic brain injury (TBI) by conducting secondary analyses of established datasets that were originally created through clinical trials, survey-based studies, or natural history research. Because many TBI datasets already include rich longitudinal follow-up and detailed clinical information, the FOA emphasizes taking advantage of these resources to answer additional questions about survival, how TBI-related problems evolve over time (progression), and how people respond to rehabilitation and recover in real-world settings. The overall focus is on outcomes that matter to medical rehabilitation, meaning functional recovery, participation in daily life, and longer-term health and quality-of-life impacts that can be studied using existing data.
This opportunity used the NIH R21 mechanism, which is commonly intended for exploratory, developmental, or early-stage projects that can produce impactful results without the scale of a large multi-year clinical study. In practical terms, that means applicants were expected to propose a clearly defined analytic plan that uses an existing database to test hypotheses, explore relationships, identify predictors of outcomes, or characterize patterns of recovery and rehabilitation-related results in people with TBI. The FOA highlights that datasets coming from trials, surveys, and natural history cohorts can be mined to better understand trajectories of outcomes, subgroups of patients who do better or worse, and factors linked to meaningful recovery. It also implicitly encourages work that can inform future clinical research directions and rehabilitation practice by uncovering evidence that may already be present in underused data.
Administratively, this was a discretionary grant opportunity in the Health activity area, listed under CFDA 93.865 (Child Health and Human Development Extramural Research), and it was issued by the National Institutes of Health. The program did not require cost sharing or matching, which means applicants were not required to contribute non-federal funds as a condition of receiving an award. The FOA was posted on July 7, 2015, with an application due date of October 30, 2015, and an archive date of November 30, 2015, indicating it is no longer open for submission. The estimated total funding available across awards was $1,500,000, and the award ceiling was $200,000, which sets the upper limit on the amount that could be requested per award under the terms described in the listing. As with many NIH opportunities, the actual number of awards would typically depend on the quality of applications and available funds, but the provided totals indicate a modest portfolio of small exploratory awards.
Eligibility for this FOA was broad and included a wide range of domestic and non-domestic entities. Eligible applicants included federal, state, county, city or township, special district governments, and U.S. territory or possession entities; public and state-controlled institutions of higher education and private institutions of higher education; nonprofit organizations with or without 501(c)(3) status; for-profit organizations (including small businesses); public housing authorities/Indian housing authorities; and Native American tribal governments (federally recognized) as well as other tribal organizations. The eligibility section also explicitly included Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; regional organizations; foreign organizations (non-U.S. entities); and eligible federal agencies. This breadth suggests NIH intended to encourage participation from many types of organizations that might hold relevant TBI datasets, have analytic expertise, or have strong rehabilitation research programs.
For applicants or researchers seeking the official archived announcement and full details, the FOA provided an additional information link hosted by NIH at: http://grants.nih.gov/grants/guide/rfa-files/RFA-HD-16-001.html. For technical issues accessing or linking to the announcement, the contact route listed was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs)
What is the name of this NIH funding opportunity?
The funding opportunity is titled "Secondary Analysis of Existing Databases in Traumatic Brain Injury to Explore Outcomes Relevant to Medical Rehabilitation (R21)."
What is the Funding Opportunity Number (FOA number)?
The Funding Opportunity Number is RFA-HD-16-001.
Which agency issued this funding opportunity?
This opportunity was issued by the National Institutes of Health (NIH).
What activity area is this opportunity listed under?
It is listed under the Health activity area.
What CFDA number is associated with this opportunity?
The opportunity is listed under CFDA 93.865 (Child Health and Human Development Extramural Research).
What is the main purpose of this FOA?
The central purpose is to fund research that re-uses and re-analyzes existing traumatic brain injury (TBI) databases to generate new insights relevant to medical rehabilitation outcomes, rather than collecting new primary data.
What type of research approach does this FOA emphasize?
It emphasizes secondary analysis of established datasets, including databases originally created through clinical trials, survey-based studies, or natural history research.
Does this funding opportunity support collecting new primary data?
The opportunity was designed to support re-use and re-analysis of data that already exist, rather than collecting new primary data.
What kinds of datasets are specifically mentioned as appropriate sources for analysis?
The FOA highlights existing datasets created through clinical trials, survey-based studies, and natural history research.
Why does the FOA focus on existing TBI datasets?
It notes that many TBI datasets already include rich longitudinal follow-up and detailed clinical information, creating an opportunity to answer additional questions using resources that are already available.
What outcomes does the FOA prioritize?
The FOA prioritizes outcomes relevant to medical rehabilitation, including functional recovery, participation in daily life, and longer-term health and quality-of-life impacts.
What TBI-related questions does the FOA suggest can be studied through secondary analysis?
It emphasizes additional questions related to survival, how TBI-related problems evolve over time (progression), and how people respond to rehabilitation and recover in real-world settings.
What does "medical rehabilitation outcomes" mean in the context of this FOA?
In this FOA, outcomes relevant to medical rehabilitation include functional recovery, participation in daily life, and longer-term health and quality-of-life impacts that can be studied using existing data.
What grant mechanism does this opportunity use?
This opportunity used the NIH R21 mechanism.
What does the NIH R21 mechanism imply about project scope?
The R21 mechanism is commonly intended for exploratory, developmental, or early-stage projects that can produce impactful results without the scale of a large multi-year clinical study.
What would applicants typically be expected to propose under this FOA?
Applicants were expected to propose a clearly defined analytic plan using an existing database to test hypotheses, explore relationships, identify predictors of outcomes, or characterize patterns of recovery and rehabilitation-related results in people with TBI.
What types of analytic goals are explicitly encouraged?
The FOA highlights work that can examine trajectories of outcomes, identify subgroups of patients who do better or worse, and evaluate factors linked to meaningful recovery using existing data.
How might results from these secondary analyses be used, according to the FOA?
The FOA indicates that findings may inform future clinical research directions and rehabilitation practice by uncovering evidence that may already be present in underused data.
Is cost sharing or matching required?
No. The program did not require cost sharing or matching.
What does it mean that cost sharing or matching is not required?
It means applicants were not required to contribute non-federal funds as a condition of receiving an award.
How much total funding was estimated to be available?
The estimated total funding available across awards was $1,500,000.
What was the award ceiling for this opportunity?
The award ceiling was $200,000, which set the upper limit on the amount that could be requested per award under the terms described in the listing.
How many awards were expected to be made?
The information provided notes that the actual number of awards would typically depend on the quality of applications and available funds; an exact number of awards is not specified.
When was the FOA posted?
The FOA was posted on July 7, 2015.
What was the application due date?
The application due date was October 30, 2015.
Is this FOA currently open for submission?
No. The archive date was November 30, 2015, indicating it is no longer open for submission.
What does the archive date indicate?
The archive date (November 30, 2015) indicates the opportunity is no longer active for new submissions.
Who was eligible to apply?
Eligibility was broad and included many domestic and non-domestic entities, including various government entities, institutions of higher education, nonprofits, for-profits (including small businesses), tribal governments and organizations, foreign organizations, and eligible federal agencies.
Are non-U.S. (foreign) organizations eligible?
Yes. The eligibility section explicitly included foreign organizations (non-U.S. entities).
Are for-profit organizations eligible to apply?
Yes. For-profit organizations, including small businesses, were listed as eligible applicants.
Are nonprofit organizations eligible even if they do not have 501(c)(3) status?
Yes. Nonprofit organizations with or without 501(c)(3) status were included as eligible applicants.
Are institutions of higher education eligible?
Yes. Both public and state-controlled institutions of higher education and private institutions of higher education were included as eligible applicants.
Are government entities eligible, and if so, which types?
Yes. Eligible government entities included federal, state, county, city or township, special district governments, and U.S. territory or possession entities.
Are tribal governments and tribal organizations eligible?
Yes. Native American tribal governments (federally recognized) and other tribal organizations were listed as eligible.
Are U.S. federally recognized housing authorities eligible?
Public housing authorities/Indian housing authorities were listed as eligible applicants.
Does the FOA mention eligibility for specific institution types such as HBCUs and HSIs?
Yes. The eligibility section explicitly included HBCUs, Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISISs).
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations were explicitly included in the eligibility list.
Are regional organizations eligible?
Yes. Regional organizations were explicitly included as eligible applicants.
Where can someone find the official archived FOA announcement?
The FOA provided an NIH link for the official archived announcement: http://grants.nih.gov/grants/guide/rfa-files/RFA-HD-16-001.html
Who should be contacted for technical issues accessing or linking to the FOA?
For technical issues, the FOA lists the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
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