Opportunity Information: Apply for RFA DA 09 020

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Secondary Data Analyses for Substance Abuse Research (R21/R33)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
  • This funding opportunity was created on Nov 5, 2008 and posted on Nov 5, 2008.
  • Applicants must submit their applications by Jan 28, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Independent school districts City or township governments Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education For profit organizations other than small businesses Special district governments Small businesses County governments Public housing authorities/Indian housing authorities Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
Apply for RFA DA 09 020

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Opportunity Summary:

Secondary Data Analyses for Substance Abuse Research (R21/R33) is a National Institute on Drug Abuse (NIDA), National Institutes of Health funding opportunity that supports projects using existing, high-value biological datasets to answer important questions in substance abuse and addiction research. The core idea is to get more scientific return from already-collected data by funding teams that can perform rigorous secondary analyses, while also improving the data and computational infrastructure needed to carry out those analyses effectively. In practical terms, applicants are expected to propose both the scientific work (the actual analyses that will produce new findings) and the informatics or computational advances that make those analyses possible, reproducible, and broadly useful.

This opportunity uses the Exploratory/Developmental Phased Innovation grant mechanism (R21/R33), which means applicants must submit one integrated application that is explicitly divided into two sequential phases. The R21 phase is intended for early-stage, exploratory, or proof-of-concept activities, such as validating analytical approaches, harmonizing or preparing complex datasets, demonstrating feasibility, and establishing the computational workflows or infrastructure required for the larger effort. The R33 phase supports the expanded or fully developed stage of the project, where the team carries out the more comprehensive analyses and delivers the mature infrastructure outcomes proposed. A key rule is that applications must include both phases; proposals that request only an R21 or only an R33 will not be considered.

Funding is competitive and depends on scientific and technical merit, NIDA program priorities, and available appropriations. NIDA anticipated committing about $2,000,000 in FY 2009 for this announcement, with an expected 7 to 10 awards. Because projects could vary widely in scope and complexity, the agency indicated that award sizes and project durations could also vary, rather than forcing a one-size-fits-all budget or timeline. The listing shows an award ceiling of $200,000, signaling an upper bound that applicants should factor into planning.

Eligibility is broad and includes many types of organizations. Eligible applicants span public and private institutions of higher education, nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status), for-profit organizations (including small businesses and other than small businesses), and a range of government entities (state, county, city/township, special district governments, and independent school districts). Tribal governments and tribal organizations are eligible, including federally recognized tribal governments and other tribal entities, as are public housing authorities and Indian housing authorities. The announcement also explicitly includes various institution types and community-based entities, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and even non-U.S. (foreign) organizations.

Administrative details place this opportunity in the discretionary grant category, with a health-related funding activity focus tied to drug abuse and addiction research (CFDA 93.279). There is no cost-sharing or matching requirement. The opportunity was posted on November 5, 2008, with an application closing date of January 28, 2009, and an archive date of February 28, 2009. The official funding opportunity number is RFA-DA-09-020, and further details were provided through the NIH Grants Guide posting associated with that RFA. For technical issues accessing or linking to the announcement, the NIH Office of Extramural Research webmaster contact was provided.

Frequently Asked Questions (FAQs)

What is the Secondary Data Analyses for Substance Abuse Research (R21/R33) opportunity?

This is a National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH) funding opportunity that supports research projects using existing, high-value biological datasets to answer important questions in substance abuse and addiction research.

What is the main purpose of this funding opportunity?

The purpose is to get more scientific return from already-collected data by supporting rigorous secondary analyses. The opportunity also aims to strengthen the data and computational infrastructure needed to conduct those analyses effectively, reproducibly, and in ways that are broadly useful.

What type of data does the opportunity focus on?

The opportunity focuses on existing, high-value biological datasets. Projects are expected to use data that has already been collected rather than generating new primary datasets.

What does "secondary data analysis" mean in this context?

In this context, secondary data analysis means analyzing already-existing datasets to produce new findings or insights, rather than collecting new data as the primary activity.

What research area is this opportunity tied to?

It is tied to substance abuse and addiction research within a health-related funding activity area focused on drug abuse.

Which NIH institute is sponsoring this opportunity?

The sponsoring institute is the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH).

What grant mechanism is used for this opportunity?

This opportunity uses the Exploratory/Developmental Phased Innovation grant mechanism (R21/R33).

What does the R21/R33 phased mechanism require from applicants?

Applicants must submit one integrated application that is explicitly divided into two sequential phases: an R21 phase followed by an R33 phase.

Can an application request only an R21 phase or only an R33 phase?

No. Applications must include both phases. Proposals that request only an R21 or only an R33 will not be considered.

What is the purpose of the R21 phase in this opportunity?

The R21 phase is intended for early-stage, exploratory, or proof-of-concept activities. Examples described include validating analytical approaches, harmonizing or preparing complex datasets, demonstrating feasibility, and establishing the computational workflows or infrastructure required for the larger effort.

What is the purpose of the R33 phase in this opportunity?

The R33 phase supports the expanded or fully developed stage of the project. This is where the team carries out more comprehensive analyses and delivers the mature infrastructure outcomes proposed in the application.

What are applicants expected to propose besides the scientific analyses?

Applicants are expected to propose both (1) the scientific work that will produce new findings and (2) informatics or computational advances that make the analyses possible, reproducible, and broadly useful.

Does the opportunity emphasize reproducibility?

Yes. The opportunity explicitly highlights improving computational workflows or infrastructure so analyses can be carried out effectively and reproducibly, with outcomes intended to be broadly useful.

Is funding guaranteed if an application meets eligibility requirements?

No. Funding is competitive and depends on scientific and technical merit, NIDA program priorities, and available appropriations.

How much funding did NIDA anticipate committing for this announcement?

NIDA anticipated committing about $2,000,000 in FY 2009 for this announcement.

How many awards were expected?

The announcement indicated an expectation of approximately 7 to 10 awards.

Are award sizes and project durations fixed?

No. The agency indicated that award sizes and project durations could vary depending on project scope and complexity, rather than using a single standard budget or timeline for all projects.

Is there an award ceiling listed for this opportunity?

Yes. The listing shows an award ceiling of $200,000, which signals an upper bound applicants should factor into planning.

Is cost-sharing or matching required?

No. There is no cost-sharing or matching requirement for this opportunity.

What is the funding opportunity number?

The official funding opportunity number is RFA-DA-09-020.

Where were additional official details posted?

Further details were provided through the NIH Grants Guide posting associated with RFA-DA-09-020.

When was the opportunity posted?

The opportunity was posted on November 5, 2008.

What was the application closing date?

The application closing date was January 28, 2009.

When was the archive date?

The archive date was February 28, 2009.

What type of grant category is this?

This opportunity is listed as a discretionary grant.

What is the CFDA number associated with this opportunity?

The CFDA number listed is 93.279.

What types of organizations are eligible to apply?

Eligibility is broad and includes public and private institutions of higher education, nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status), for-profit organizations (including small businesses and other-than-small businesses), and multiple types of government entities.

Which government entities are eligible?

Eligible government entities include state governments, county governments, city or township governments, special district governments, and independent school districts.

Are tribal governments and tribal organizations eligible?

Yes. Federally recognized tribal governments and other tribal entities are eligible, as are tribal organizations.

Are public housing authorities eligible?

Yes. Public housing authorities and Indian housing authorities are listed as eligible applicants.

Are minority-serving institutions specifically included in eligibility?

Yes. The announcement explicitly includes institutions such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, and Tribally Controlled Colleges and Universities (TCCUs).

Are faith-based or community-based organizations eligible?

Yes. Faith-based or community-based organizations are explicitly included among eligible applicants.

Are regional organizations eligible?

Yes. Regional organizations are explicitly included as eligible applicants.

Are U.S. territories or possessions eligible?

Yes. U.S. territories or possessions are explicitly included in the eligibility list.

Are non-U.S. (foreign) organizations eligible to apply?

Yes. The eligibility list explicitly includes non-U.S. (foreign) organizations.

What should applicants do if they have technical issues accessing or linking to the announcement?

The announcement provided a contact for technical issues: the NIH Office of Extramural Research webmaster.

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