Opportunity Information: Apply for PAR 10 033
Apply for PAR 10 033
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Selected Topics in Transfusion Medicine (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.839 Blood Diseases and Resources Research.
- This funding opportunity was created on Nov 24, 2009 and posted on Nov 24, 2009.
- Applicants must submit their applications by Jan 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Private institutions of higher education State governments City or township governments Native American tribal governments (Federally recognized) Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) Public housing authorities/Indian housing authorities Small businesses County governments Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Selected Topics in Transfusion Medicine (R21) opportunity (Funding Opportunity Number PAR-10-033) is an NIH grant program issued by the National Heart, Lung, and Blood Institute (NHLBI) to support exploratory and developmental research that can directly inform real-world blood banking and transfusion practices. The central idea is to encourage studies that help determine what should be done, and how it should be done, across the transfusion pipeline, from donor recruitment and donation safety to blood product handling and patient outcomes. NHLBI frames this work as a major public health need because blood transfusion remains extremely common in the United States, with roughly five million patients receiving transfusions each year, and because even modern transfusion medicine still carries meaningful risks.
The scientific focus is broadly on improving both safety and availability of the blood supply. On the safety side, the announcement emphasizes understanding why transfusion-associated adverse events happen and identifying practical ways to reduce them. This includes both infectious risks (such as pathogen transmission) and non-infectious risks (such as immunologic or other transfusion reactions). On the availability side, the program highlights the importance of maintaining an adequate blood supply by reducing risks associated with the donation process itself and by developing better strategies for donor recruitment and retention. In other words, NHLBI is looking for research that can clarify determinants of complications and system bottlenecks, and then translate that understanding into safer, more reliable transfusion medicine and blood banking operations.
This program uses the NIH Exploratory/Developmental Research Grant mechanism (R21), which is typically suited for early-stage, high-impact ideas, feasibility testing, pilot data generation, and novel approaches that may be too preliminary for a larger traditional grant. The FOA notes that it runs in parallel with a companion opportunity of the same scientific scope under the R01 mechanism (PAR-10-034), which is generally intended for more mature, fully developed projects. Applicants should interpret that pairing as a signal that NHLBI is supporting a pipeline of work in this area, from early exploratory studies (R21) through larger, more definitive projects (R01).
In terms of funding parameters, the listing provides an award ceiling of $200,000 and states that the size and duration of awards can vary depending on the proposed research. It also makes clear that the total amount funded and the number of awards are not fixed in advance; they depend on the number of applications received, their scientific quality, their budgets, and their project periods. There is no cost sharing or matching requirement.
Eligibility is broad and includes many types of U.S.-based organizations such as public and private institutions of higher education, nonprofits (including 501(c)(3) and non-501(c)(3) entities), state and local governments, tribal governments and tribal organizations, public housing authorities/Indian housing authorities, independent school districts, small businesses, and for-profit organizations (other than small businesses). The FOA also explicitly includes a range of additional eligible applicants such as Hispanic-serving institutions, HBCUs, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, faith-based or community-based organizations, eligible federal agencies, U.S. territories or possessions, and even non-U.S. entities (foreign organizations) and regional organizations, as specified in the eligibility information.
Administratively, the opportunity is categorized as a discretionary grant under the health activity category, with CFDA number 93.839 (Blood Diseases and Resources Research). It was posted on November 24, 2009, and the original and current closing date listed is January 7, 2013, with an archive date of February 7, 2013, indicating the announcement is no longer active as a current competition. For historical reference and full details, the FOA points to the NIH grants guide page for PAR-10-033, and provides NIH Office of Extramural Research (OER) webmaster contacts for technical access issues.
Frequently Asked Questions (FAQs): Selected Topics in Transfusion Medicine (R21) - PAR-10-033
What is the Selected Topics in Transfusion Medicine (R21) opportunity?
It is an NIH grant funding opportunity (PAR-10-033) issued by the National Heart, Lung, and Blood Institute (NHLBI) to support exploratory and developmental research that can directly inform real-world blood banking and transfusion practices.
Which NIH institute sponsors this program?
The program is issued by NHLBI (National Heart, Lung, and Blood Institute), which is part of the National Institutes of Health (NIH).
What is the main goal of this FOA?
The central goal is to encourage studies that help determine what should be done, and how it should be done, across the transfusion pipeline, from donor recruitment and donation safety to blood product handling and patient outcomes.
Why does NHLBI describe this area as a major public health need?
NHLBI frames the work as a major public health need because blood transfusion is extremely common in the United States (roughly five million patients receive transfusions each year) and because transfusion medicine still carries meaningful risks, even with modern practices.
What types of research topics does the FOA emphasize?
The FOA broadly emphasizes research to improve both the safety and availability of the blood supply, including research that clarifies determinants of complications and system bottlenecks and translates that understanding into safer, more reliable transfusion medicine and blood banking operations.
What does the FOA mean by the "transfusion pipeline"?
Based on the description provided, the transfusion pipeline spans donor recruitment and retention, donation safety, blood product handling, and downstream patient outcomes after transfusion.
What does "safety of the blood supply" cover in this FOA?
Safety-focused work includes understanding why transfusion-associated adverse events occur and identifying practical ways to reduce them, covering both infectious risks (such as pathogen transmission) and non-infectious risks (such as immunologic or other transfusion reactions).
Does the FOA include infectious risk research?
Yes. The announcement explicitly includes infectious risks, such as pathogen transmission, as part of transfusion-associated adverse events that research may address.
Does the FOA include non-infectious risk research?
Yes. The FOA also highlights non-infectious risks, including immunologic or other transfusion reactions, and encourages research that can reduce these adverse events.
What does "availability of the blood supply" mean in this FOA?
Availability-focused work includes maintaining an adequate blood supply by reducing risks associated with the donation process itself and by developing better strategies for donor recruitment and retention.
What kinds of studies is the R21 mechanism intended to support here?
The FOA uses the NIH Exploratory/Developmental Research Grant mechanism (R21), which is typically used for early-stage, high-impact ideas, feasibility testing, pilot data generation, and novel approaches that may be too preliminary for a larger traditional grant.
Is there a companion funding opportunity for more mature projects?
Yes. The FOA notes a companion opportunity with the same scientific scope under the R01 mechanism (PAR-10-034), which is generally intended for more mature, fully developed projects.
How should applicants interpret the R21/R01 pairing mentioned in the FOA?
The pairing is described as a signal that NHLBI is supporting a pipeline of work in this area, from early exploratory studies (R21) through larger, more definitive projects (R01).
What is the maximum award amount mentioned for this opportunity?
The listing provides an award ceiling of $200,000.
Are award size and duration fixed?
No. The description states that the size and duration of awards can vary depending on the proposed research.
Is the number of awards or total funding pre-set?
No. The FOA indicates that the total amount funded and the number of awards are not fixed in advance and depend on factors such as the number of applications received, scientific quality, budgets, and project periods.
Is cost sharing or matching required?
No. The opportunity explicitly states there is no cost sharing or matching requirement.
What types of organizations are eligible to apply?
Eligibility is broad and includes many types of U.S.-based organizations, such as public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and non-501(c)(3)), state and local governments, tribal governments and tribal organizations, public housing authorities/Indian housing authorities, independent school districts, small businesses, and for-profit organizations (other than small businesses).
Are minority-serving and community-based institutions included in the eligible applicants?
Yes. The FOA explicitly includes a range of additional eligible applicants such as Hispanic-serving institutions, HBCUs, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, and faith-based or community-based organizations.
Are federal agencies eligible to apply?
Yes. The eligibility information explicitly includes eligible federal agencies.
Are U.S. territories or possessions eligible to apply?
Yes. The eligibility information explicitly includes U.S. territories or possessions.
Are non-U.S. organizations allowed to apply?
Yes. The eligibility information explicitly includes non-U.S. entities (foreign organizations) and regional organizations, as specified in the eligibility information.
How is this opportunity categorized administratively?
It is categorized as a discretionary grant under the health activity category.
What CFDA number is associated with this opportunity?
The CFDA number listed is 93.839 (Blood Diseases and Resources Research).
When was this funding opportunity posted?
It was posted on November 24, 2009.
What are the closing date and archive date listed for this FOA?
The original and current closing date listed is January 7, 2013, and the archive date is February 7, 2013.
Is this FOA currently active?
No. The closing and archive dates indicate the announcement is no longer active as a current competition.
Where does the FOA direct users for historical reference and full details?
It points to the NIH grants guide page for PAR-10-033 for historical reference and full details.
Who is listed for technical access issues related to the FOA?
The FOA provides NIH Office of Extramural Research (OER) webmaster contacts for technical access issues.
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