Opportunity Information: Apply for PA 14 343

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Self Management for Health in Chronic Conditions (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173 Research Related to Deafness and Communication Disorders 93.361 Nursing Research 93.866 Aging Research.
  • This funding opportunity was created on Sep 19, 2014 and posted on Sep 19, 2014.
  • Applicants must submit their applications by Jan 7, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $275,000.00 in funding.
  • Eligible applicants include: Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) City or township governments County governments Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Public and State controlled institutions of higher education State governments Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The Self Management for Health in Chronic Conditions (R21) opportunity (Funding Opportunity Number PA 14-343) is a National Institutes of Health (NIH) discretionary grant program designed to fund exploratory and developmental research that advances the science of self-management across chronic diseases and conditions. The central idea is that chronic illness is not just a set of separate, disease-specific problems, but a national public health challenge that often cuts across diagnoses and life circumstances. Building on an Institute of Medicine report that frames chronic conditions as a leading U.S. health challenge, the program encourages research that is broadly applicable across conditions rather than narrowly tailored to a single disease area, with the longer-term goal of reducing the overall burden of chronic illness on individuals, families, communities, and healthcare systems.

In this program, "self-management" is defined in a practical and holistic way: it is what individuals do, together with support from family members, community resources, and healthcare professionals, to handle the day-to-day realities of chronic illness. That includes managing symptoms and medical treatments, making and sustaining lifestyle changes, and coping with psychosocial impacts like stress, depression, stigma, and social isolation. It also explicitly recognizes cultural and spiritual consequences and supports, reflecting the reality that chronic conditions affect identity, roles, relationships, and meaning, not just physical functioning. The FOA positions self-management as a mainstream scientific area in its own right, suggesting an interest in building generalizable theories, tools, and interventions that can translate across different chronic conditions and populations.

This is an R21 mechanism, which typically supports early-stage, innovative, or high-impact pilot work that can generate foundational evidence for larger studies later. The listed award ceiling is $275,000. The announcement indicates no cost-sharing or matching requirement. The funding activity categories are Education and Health, and the CFDA numbers associated with the opportunity include 93.173 (Research Related to Deafness and Communication Disorders), 93.361 (Nursing Research), and 93.866 (Aging Research), signaling that NIH is aligning the topic with multiple research domains where self-management is especially relevant, including communication-related disabilities, nursing-led behavioral and care delivery research, and aging-related chronic disease management.

Eligibility is broad and includes a wide range of public and private organizations. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public housing authorities and Indian housing authorities; federally recognized tribal governments and other tribal organizations; public and private institutions of higher education; nonprofits both with and without 501(c)(3) status (other than institutions of higher education); small businesses; and other for-profit organizations that are not small businesses. The FOA also explicitly includes institutions and organizations that serve specific populations, such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American and Native American Pacific Islander Serving Institutions (AANAPISIs). Faith-based and community-based organizations and eligible federal agencies are also listed, emphasizing the expectation that meaningful self-management research may be rooted in community settings and implemented through diverse systems, not only academic medical centers.

Notably, the opportunity allows non-U.S. participation: non-domestic (foreign) organizations and foreign institutions may apply, non-domestic components of U.S. organizations are eligible, and foreign components are allowed as defined in NIH policy. This matters because chronic disease self-management is influenced by culture, health system design, and community infrastructure, and cross-national work can strengthen the generalizability of findings or test approaches in different contexts.

Key administrative details show that this funding announcement was posted and created on September 19, 2014, with an original and current closing date of January 7, 2018, and an archive date of February 7, 2018, meaning the specific FOA is no longer active but remains important as a reference for NIH priorities and for locating related or reissued opportunities. The full announcement was hosted by NIH at the provided grants.nih.gov link, and NIH’s Office of Extramural Research (OER) webmaster contact is listed for access and technical issues.

Frequently Asked Questions (FAQs)

What is the Self Management for Health in Chronic Conditions (R21) opportunity?

The Self Management for Health in Chronic Conditions (R21) opportunity is a National Institutes of Health (NIH) discretionary grant program intended to support exploratory and developmental research that advances the science of self-management across chronic diseases and conditions.

What is the Funding Opportunity Number (FOA number) for this program?

The Funding Opportunity Number is PA 14-343.

What is the main purpose of this funding opportunity?

The program is designed to fund early-stage, innovative research that can strengthen the evidence base for self-management approaches that apply broadly across chronic conditions, with the longer-term goal of reducing the overall burden of chronic illness on individuals, families, communities, and healthcare systems.

Why does the FOA emphasize research that cuts across chronic diseases?

The FOA frames chronic illness as a major public health challenge that often spans diagnoses and life circumstances. It encourages research that is broadly applicable across conditions rather than narrowly tailored to a single disease area, reflecting the idea that many self-management challenges and supports are shared across chronic conditions.

How does this FOA define "self-management"?

In this FOA, self-management is defined as what individuals do, with support from family members, community resources, and healthcare professionals, to manage the day-to-day realities of chronic illness. This includes managing symptoms and medical treatments, making and sustaining lifestyle changes, and coping with psychosocial impacts.

What types of psychosocial impacts are included in the self-management definition?

The FOA explicitly includes psychosocial impacts such as stress, depression, stigma, and social isolation as part of what self-management may need to address.

Does the FOA recognize cultural or spiritual aspects of chronic illness self-management?

Yes. The description explicitly recognizes cultural and spiritual consequences and supports, acknowledging that chronic conditions can affect identity, roles, relationships, and meaning, not only physical functioning.

What does the "R21" mechanism mean in this context?

This opportunity uses the NIH R21 mechanism, which typically supports exploratory and developmental work. It is generally aligned with early-stage, innovative, or high-impact pilot studies that can generate foundational evidence for larger future studies.

What is the maximum award amount (award ceiling) listed for this opportunity?

The listed award ceiling is $275,000.

Is cost-sharing or matching required?

No. The announcement indicates there is no cost-sharing or matching requirement.

What funding activity categories are associated with this FOA?

The funding activity categories listed are Education and Health.

Which CFDA numbers are associated with this opportunity?

The CFDA numbers associated with the opportunity include 93.173 (Research Related to Deafness and Communication Disorders), 93.361 (Nursing Research), and 93.866 (Aging Research).

What do the associated CFDA numbers suggest about the program's scope?

The CFDA numbers signal that NIH aligns this topic with multiple domains where self-management is particularly relevant, including communication-related disabilities, nursing-led behavioral and care delivery research, and aging-related chronic disease management.

Who is eligible to apply?

Eligibility is broad and includes many public and private organization types. Eligible applicants include state governments, county governments, city or township governments, special district governments, independent school districts, public housing authorities and Indian housing authorities, federally recognized tribal governments and other tribal organizations, public and private institutions of higher education, nonprofits (with or without 501(c)(3) status, other than institutions of higher education), small businesses, and other for-profit organizations that are not small businesses.

Are minority-serving institutions specifically included as eligible applicants?

Yes. The FOA explicitly includes institutions and organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American and Native American Pacific Islander Serving Institutions (AANAPISIs).

Are faith-based and community-based organizations eligible?

Yes. Faith-based and community-based organizations are listed as eligible applicants.

Are federal agencies eligible to apply?

Yes. Eligible federal agencies are listed among the eligible applicant types.

Does this FOA allow non-U.S. or foreign applicants?

Yes. The opportunity allows non-U.S. participation. Non-domestic (foreign) organizations and foreign institutions may apply, non-domestic components of U.S. organizations are eligible, and foreign components are allowed as defined in NIH policy.

Why might foreign participation be relevant for this topic?

The FOA notes that chronic disease self-management is influenced by culture, health system design, and community infrastructure. Cross-national work can help strengthen generalizability or test approaches in different contexts.

When was this funding announcement created and posted?

The announcement was created and posted on September 19, 2014.

What were the closing and archive dates for this FOA?

The original and current closing date was January 7, 2018, and the archive date was February 7, 2018.

Is this specific FOA currently active?

No. Based on the provided dates (closing date in January 2018 and archive date in February 2018), the specific FOA is no longer active, though it may remain useful as a reference for NIH priorities and for identifying related or reissued opportunities.

Where was the full announcement hosted?

The full announcement was hosted by NIH on grants.nih.gov (via the link referenced in the opportunity description).

Who is listed as the contact for access or technical issues related to the announcement?

NIH's Office of Extramural Research (OER) webmaster contact is listed for access and technical issues.

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