Opportunity Information: Apply for RFA DA 16 015

  • The HHS-NIH11 in the education, health sector is offering a public funding opportunity titled "Services Planning Research in the Appalachian Region to Address Adverse Health Consequences Associated with Increased Opioid Injection Drug Use (R03)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279,.
  • This funding opportunity was created on Feb 19, 2016 and posted on Feb 19, 2016.
  • Applicants must submit their applications by Apr 28, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $100,000.00 in funding.
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for RFA DA 16 015

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Opportunity Summary:

The funding opportunity titled "Services Planning Research in the Appalachian Region to Address Adverse Health Consequences Associated with Increased Opioid Injection Drug Use (R03)" (Funding Opportunity Number RFA-DA-16-015) is a National Institutes of Health (NIH) grant program under the U.S. Department of Health and Human Services (HHS). It focuses on short, targeted services planning research intended to help communities and researchers better understand and respond to health harms linked to rising opioid injection drug use in Appalachia. The program is specifically designed to support one-year projects that combine local epidemiologic assessment with a practical inventory of existing services, so that future interventions and larger research efforts can be designed with a clearer picture of both the problem and the on-the-ground capacity to address it.

At its core, the FOA is asking applicants to build an epidemiologic understanding of opioid injection drug use and related risks, especially the transmission and burden of Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV). In addition to HCV and HIV, applicants are expected to consider other adverse health consequences associated with injection drug use. The emphasis is on producing actionable planning knowledge: work that clarifies where risk is increasing, what patterns of use and risk behavior look like in a given area, and what gaps exist between community needs and available prevention, testing, treatment, and harm reduction resources.

A key feature of this opportunity is its geographic focus. Projects must be situated in any of the 420 counties officially designated as part of the Appalachian region (as listed by the Appalachian Regional Commission). This regional scope reflects the FOA's intent to support locally grounded assessments that take into account the unique rural and small-city contexts found across Appalachia, including how healthcare access, stigma, service availability, transportation barriers, and resource constraints can shape both disease risk and service delivery.

The award mechanism is an NIH R03, which is generally used for small, short-duration projects. Here, the FOA explicitly supports one-year services planning research grants, with an award ceiling of $100,000. That structure signals that NIH is not primarily looking for large clinical trials or long-term implementation programs under this announcement. Instead, it is looking for well-scoped projects that can quickly generate the kind of evidence and service mapping needed to strengthen current responses and set up future intervention development, program improvement, and larger-scale research proposals.

The funding opportunity is open to a broad range of eligible applicants, reflecting the fact that meaningful planning research in this area often requires partnerships across public health, healthcare, academia, and community organizations. Eligible applicants include state, county, and local governments; public and private institutions of higher education; tribal governments and tribal organizations; public housing authorities; nonprofit organizations (with or without 501(c)(3) status); for-profit organizations (other than small businesses); small businesses; and other entities as described in the FOA's additional eligibility language. This broad eligibility is consistent with the FOA's practical orientation: communities may already have relevant data and service infrastructure housed in health departments, hospitals, universities, community-based organizations, or cross-sector coalitions, and the program is designed to allow whichever entity is best positioned locally to take the lead.

In terms of expected outputs and impact, the FOA is geared toward producing planning-ready findings that can directly inform decision-making. That includes identifying what programs and resources currently exist to address opioid injection drug use and its health consequences, how well those resources match community needs, and what barriers prevent people from accessing prevention and care. The intention is that the results will help improve existing interventions, guide the development of new programs, and provide a stronger foundation for future, more comprehensive research efforts aimed at reducing injection-related harms, preventing outbreaks, and improving health outcomes in Appalachian communities.

Administratively, the opportunity was posted on February 19, 2016, with a closing date of April 28, 2016, and it is listed under CFDA numbers 93.279. The sponsoring agency is identified as HHS-NIH11, indicating an NIH institute/center involvement, and the overall category is Education and Health. Even though the posting dates are historical, the FOA summary remains useful as a model for how NIH frames rapid, planning-oriented research: defined geography, focused time horizon, modest budget, and a requirement that epidemiologic understanding and service landscape assessment be integrated to support real-world intervention planning.

Frequently Asked Questions (FAQs)

What is the title of this funding opportunity?

The funding opportunity is titled "Services Planning Research in the Appalachian Region to Address Adverse Health Consequences Associated with Increased Opioid Injection Drug Use (R03)."

What is the Funding Opportunity Number (FOA number)?

The Funding Opportunity Number is RFA-DA-16-015.

Which federal agency sponsors this opportunity?

This is a National Institutes of Health (NIH) grant program under the U.S. Department of Health and Human Services (HHS). The sponsoring agency is identified as HHS-NIH11.

What is the main purpose of this FOA?

The FOA supports short, targeted services planning research to help communities and researchers better understand and respond to health harms linked to rising opioid injection drug use in Appalachia. It is designed to generate practical, planning-ready findings that inform future interventions and larger research efforts.

What kind of projects does this FOA support?

The FOA supports one-year projects that combine (1) a local epidemiologic assessment of opioid injection drug use and related risks and (2) a practical inventory of existing services and resources, so applicants can identify gaps between needs and on-the-ground capacity.

What grant mechanism is used for this opportunity?

The award mechanism is an NIH R03, which is generally intended for small, short-duration projects. Under this FOA, it is explicitly used for one-year services planning research grants.

How long can the project period be?

The FOA is designed for one-year projects.

What is the maximum award amount?

The award ceiling is $100,000.

Is this FOA intended to fund large clinical trials or long-term implementation programs?

No. The FOA signals that NIH is not primarily seeking large clinical trials or long-term implementation programs under this announcement. It is seeking well-scoped projects that can quickly generate evidence and service mapping to strengthen current responses and set up future work.

What health issues and outcomes are emphasized?

The FOA emphasizes building an epidemiologic understanding of opioid injection drug use and related risks, especially transmission and burden of Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV). Applicants are also expected to consider other adverse health consequences associated with injection drug use.

What does "services planning research" mean in this FOA?

Based on the FOA description, services planning research refers to producing actionable planning knowledge by clarifying where risk is increasing, what patterns of use and risk behavior look like locally, what services and resources exist, how well those services match community needs, and what barriers limit access to prevention, testing, treatment, and harm reduction.

What are the required or expected components of the work?

The FOA expects applicants to integrate local epidemiologic assessment with a practical inventory of existing services. The intent is to link an understanding of the problem (risk patterns and disease burden) with an understanding of local capacity (service availability and gaps).

Where must projects be located?

Projects must be situated in any of the 420 counties officially designated as part of the Appalachian region (as listed by the Appalachian Regional Commission).

Why is the Appalachian region specifically targeted?

The FOA is intended to support locally grounded assessments that account for rural and small-city contexts across Appalachia, including how healthcare access, stigma, service availability, transportation barriers, and resource constraints can affect both disease risk and service delivery.

Who is eligible to apply?

Eligibility is broad and includes: state, county, and local governments; public and private institutions of higher education; tribal governments and tribal organizations; public housing authorities; nonprofit organizations (with or without 501(c)(3) status); for-profit organizations (other than small businesses); small businesses; and other entities as described in the FOA's additional eligibility language.

Are nonprofits required to have 501(c)(3) status to apply?

No. The FOA states that nonprofit organizations are eligible with or without 501(c)(3) status.

Are for-profit organizations eligible?

Yes. For-profit organizations (other than small businesses) are listed as eligible applicants, and small businesses are also listed as eligible.

Can government entities apply?

Yes. State, county, and local governments are explicitly listed as eligible applicants.

Can tribal governments or tribal organizations apply?

Yes. Tribal governments and tribal organizations are explicitly listed as eligible applicants.

What types of community partners does the FOA seem to anticipate?

The FOA description suggests that meaningful planning research may require partnerships across public health, healthcare, academia, and community organizations. It also notes that relevant data and service infrastructure may be housed in health departments, hospitals, universities, community-based organizations, or cross-sector coalitions.

What kinds of services are expected to be inventoried or mapped?

The FOA indicates an inventory of services and resources related to opioid injection drug use and its consequences, including prevention, testing, treatment, and harm reduction resources, as well as barriers to accessing those services.

What are examples of barriers the FOA highlights?

The FOA highlights barriers such as healthcare access limitations, stigma, service availability constraints, transportation barriers, and broader resource constraints that can shape service delivery and disease risk in Appalachian communities.

What types of findings or deliverables are expected?

The FOA is geared toward "planning-ready" findings that can directly inform decision-making, including: identifying existing programs and resources, assessing how well resources match community needs, and identifying barriers and gaps that prevent people from accessing prevention and care.

How are the results intended to be used?

The FOA states that results are intended to help improve existing interventions, guide development of new programs, and provide a stronger foundation for future, more comprehensive research efforts aimed at reducing injection-related harms, preventing outbreaks, and improving health outcomes in Appalachian communities.

What is the CFDA number associated with this opportunity?

The opportunity is listed under CFDA number 93.279.

What is the overall category for this opportunity?

The overall category is Education and Health.

When was the opportunity posted and when did it close?

The opportunity was posted on February 19, 2016, and had a closing date of April 28, 2016.

If the dates are in 2016, is the summary still useful?

Based on the information provided, the posting dates are historical, but the FOA summary is described as useful as a model for how NIH frames rapid, planning-oriented research: defined geography, focused time horizon, modest budget, and an integrated requirement for epidemiologic understanding plus service landscape assessment to support intervention planning.

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