Silvio O. Conte Digestive Diseases Research Core Centers (P30) | Apply Online

Opportunity Summary:

The Silvio O. Conte Digestive Diseases Research Core Centers (P30) funding opportunity (RFA-DK-14-012) is a National Institutes of Health grant announcement administered through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). It supports the creation or continuation of Digestive Diseases Research Core Centers (DDRCCs), which are designed to strengthen and coordinate digestive and liver disease research by building a shared infrastructure for investigators who are already conducting related work. The program is structured around the idea that research groups become more productive when they can access high-quality shared resources, interact regularly across disciplines, and use a centralized hub to spark collaborations and new ideas.

A central goal of the DDRCC program is to bring basic science and clinical investigators into closer contact so that discoveries can move more efficiently between laboratory research and patient-oriented studies. Rather than primarily funding individual research projects, this P30 mechanism focuses on “core” facilities and services that multiple investigators can use, helping reduce duplication and costs across an institution or consortium. In practical terms, a DDRCC typically supports shared technical resources, specialized instrumentation, scientific expertise, data or biostatistical support, training on methods, and other centralized services that make ongoing research more effective. The expectation is that these shared cores will foster synergy, raise the overall quality of work, and help investigators pursue new lines of inquiry that might be difficult to launch without common infrastructure.

Each applicant center is expected to be organized around a clear central theme that reflects the collective focus of the participating investigators in digestive and/or liver diseases. This thematic organization is meant to ensure the center is more than a collection of unrelated labs; the center should have a coherent scientific identity that drives collaboration and shapes which shared resources are most valuable. By anchoring the application around a defined theme, the DDRCC model emphasizes community building among researchers working on interconnected problems, with the center acting as a catalyst for communication and coordinated scientific progress.

From an administrative standpoint, this opportunity is categorized as discretionary funding using the NIH grant mechanism, with an activity category associated with food and nutrition and health, and it is linked to CFDA number 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research). The FOA anticipated making about five awards, with an estimated total funding amount of $6,000,000. The award ceiling listed is $750,000, and there is no cost-sharing or matching requirement, which means applicants are not required to contribute non-federal matching funds as a condition of the award.

Eligibility is broad across many types of U.S.-based organizations, reflecting the center-focused nature of the program. Eligible applicants include a wide range of public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status, other than institutions of higher education), for-profit organizations other than small businesses, small businesses, and multiple levels of government entities such as state, county, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities. The FOA also explicitly recognizes eligibility for various mission-driven and community-connected institutions and organizations, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and tribal governments (federally recognized and other than federally recognized, as specified).

At the same time, the announcement is clear that foreign participation is not allowed under this FOA. Non-domestic (non-U.S.) entities (foreign institutions) cannot apply, and non-domestic components of U.S. organizations are not eligible. Foreign components, as defined by the NIH Grants Policy Statement, are also not permitted. This means the work and supported infrastructure are intended to be fully U.S.-based, aligning with the program’s structure for domestic research capacity building.

The timeline information in the source data indicates the FOA was posted on May 20, 2014, with an original and current closing date of November 19, 2014, and an archive date of December 20, 2014. While those dates show this specific announcement has passed, the summary still reflects how the NIDDK DDRCC program is designed: to fund cost-effective, shared core resources that connect investigators under a unifying digestive or liver disease theme, strengthen collaboration across basic and clinical domains, and increase the efficiency and impact of ongoing research activities.

For applicants and institutions seeking details beyond the high-level structure, the full announcement was made available through the NIH grants guide under the listed link (http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-14-012.html). The provided contact path for access or technical issues was the NIH Office of Extramural Research (OER) webmaster (FBOWebmaster@OD.NIH.GOV), which is typical for problems related to finding or opening the electronic FOA materials.

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