Opportunity Information: Apply for RFA DK 11 022

  • The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Silvio O. Conte Digestive Diseases Research Core Centers (P30)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
  • This funding opportunity was created on Sep 8, 2011 and posted on Sep 8, 2011.
  • Applicants must submit their applications by Mar 30, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,500,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $750,000.00 in funding.
  • The number of recipients for this funding is limited to 2 candidate(s).
  • Eligible applicants include: For profit organizations other than small businesses Independent school districts State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Native American tribal governments (Federally recognized) Small businesses Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education City or township governments Special district governments County governments Others (see text field entitled Additional Information on Eligibility for clarification).
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:

The Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs) funding opportunity (RFA-DK-11-022) is a National Institutes of Health program administered by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) that supports center-based infrastructure for digestive and liver diseases research. It uses the NIH P30 center mechanism, which is designed to fund shared research resources and services rather than large portfolios of individual research projects. The main goal is to strengthen and connect existing basic and clinical research efforts by giving investigators access to common cores that make their work more efficient, collaborative, and innovative. In practice, these centers are intended to improve communication across disciplines, create synergy among research groups, and help generate new research ideas by lowering barriers to shared methods, technologies, and expertise.

A key expectation of a DDRCC is that it is organized around a clear central theme tied to digestive and/or liver diseases, reflecting the scientific focus of the participating investigators (often referred to as center members). The center concept is built on cost-effective shared resources, meaning the application should justify why centralized core facilities or services will measurably improve productivity and impact compared to separate, duplicative resources in individual labs. While the announcement summary does not list specific required cores, DDRCCs typically revolve around shared technical, clinical, biostatistical, data management, tissue/biorepository, imaging, genomics, or other specialized capabilities that multiple investigators can use, along with administrative structures that coordinate access, prioritization, and quality control.

This particular FOA was posted on September 8, 2011, with an original and current closing date of March 30, 2012, and it was archived on April 30, 2012. NIDDK anticipated making about 2 awards, with an estimated total funding level of $2,500,000. The award ceiling listed is $750,000, indicating the maximum expected budget level per award under this announcement. There is no cost sharing or matching requirement, which means applicants are not required to contribute non-federal funds as a condition of receiving the award.

Eligibility is broad across many U.S.-based organization types, including public and private institutions of higher education, nonprofits (including those with and without 501(c)(3) status), for-profit organizations (including small businesses), state and local governments, tribal governments and tribal organizations, public housing authorities, and other entities described in the FOA. The eligibility notes also explicitly include certain institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, U.S. territories or possessions, and eligible federal agencies. At the same time, the FOA makes clear that non-U.S. (foreign) institutions are not eligible to apply, and non-U.S. components of U.S. organizations are not eligible. Foreign components, as NIH defines them in its Grants Policy Statement, are not allowed under this announcement.

Programmatically, this opportunity sits within NIDDKs broader, integrated digestive and liver diseases research support ecosystem. The center approach is meant to amplify the value of ongoing funded research by providing shared infrastructure that helps investigators work together more effectively, standardize and improve methods, and accelerate progress in areas relevant to digestive and liver diseases. The full announcement and details were provided through NIH at http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-11-022.html, with technical access support routed through the NIH Office of Extramural Research webmaster contact listed in the notice.

Frequently Asked Questions (FAQs)

What is the Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs) funding opportunity?

It is an NIH funding opportunity (RFA-DK-11-022) administered by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to support center-based infrastructure for digestive and liver diseases research.

Which NIH institute administers this program?

The program is administered by NIDDK (National Institute of Diabetes and Digestive and Kidney Diseases) within the National Institutes of Health (NIH).

What funding mechanism does the DDRCC use?

This opportunity uses the NIH P30 center mechanism, which is intended to fund shared research resources and services (core facilities and infrastructure) rather than large portfolios of individual research projects.

What is the main purpose of a DDRCC?

The main purpose is to strengthen and connect existing basic and clinical research efforts in digestive and/or liver diseases by providing investigators access to shared cores that improve efficiency, collaboration, and innovation.

Does a DDRCC primarily fund individual research projects?

No. The P30 center mechanism is designed to support shared resources and services. The focus is on infrastructure that multiple investigators can use, not on funding a large set of individual research projects.

What kinds of activities are DDRCCs intended to enable?

DDRCCs are intended to improve communication across disciplines, create synergy among research groups, and help generate new research ideas by lowering barriers to shared methods, technologies, and expertise.

Is a central scientific theme required for a DDRCC?

Yes. A key expectation is that the DDRCC is organized around a clear central theme tied to digestive and/or liver diseases, reflecting the scientific focus of the participating investigators (often called center members).

What is meant by "shared resources" or "core facilities" in this program?

Shared resources (cores) are centralized facilities or services that multiple investigators can use. The application is expected to justify why centralized cores are more cost-effective and impactful than duplicating similar resources across individual laboratories.

Are specific cores required under this FOA summary?

The summary provided does not list specific required cores. However, DDRCCs typically revolve around shared capabilities used by multiple investigators.

What are examples of cores or shared capabilities a DDRCC might support?

Examples mentioned include shared technical, clinical, biostatistical, data management, tissue/biorepository, imaging, genomics, and other specialized capabilities, along with administrative structures that coordinate access, prioritization, and quality control.

What is expected regarding cost-effectiveness and avoiding duplication?

The center concept emphasizes cost-effective shared resources. Applicants are expected to justify that centralized core facilities or services will measurably improve productivity and impact compared to maintaining separate, duplicative resources in individual labs.

When was this funding opportunity posted and when did it close?

The FOA was posted on September 8, 2011. The original and current closing date listed is March 30, 2012.

Is this FOA still active?

No. It was archived on April 30, 2012.

How many awards did NIDDK anticipate making under this announcement?

NIDDK anticipated making about 2 awards.

What was the estimated total funding level for this FOA?

The estimated total funding level listed is $2,500,000.

What is the award ceiling for this opportunity?

The award ceiling is $750,000, indicating the maximum expected budget level per award under this announcement.

Is cost sharing or matching required?

No. There is no cost sharing or matching requirement, meaning applicants are not required to contribute non-federal funds as a condition of receiving the award.

What types of organizations are eligible to apply?

Eligibility is broad across many U.S.-based organization types, including public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), for-profit organizations (including small businesses), state and local governments, tribal governments and tribal organizations, public housing authorities, and other entities described in the FOA.

Are minority-serving institutions and community-based organizations included in eligibility?

Yes. The eligibility notes explicitly include institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations.

Are U.S. territories or possessions eligible?

Yes. U.S. territories or possessions are explicitly included as eligible in the eligibility notes.

Are federal agencies eligible to apply?

Yes. Eligible federal agencies are explicitly included among eligible applicants in the eligibility notes.

Are foreign (non-U.S.) institutions eligible to apply?

No. The FOA states that non-U.S. (foreign) institutions are not eligible to apply.

Can a U.S. organization apply if part of the work will be performed by a non-U.S. component?

No. Non-U.S. components of U.S. organizations are not eligible, and foreign components (as NIH defines them in its Grants Policy Statement) are not allowed under this announcement.

How does this program fit into NIDDK's broader research support?

This opportunity is described as part of NIDDK's broader, integrated digestive and liver diseases research support ecosystem, using a center approach to amplify the value of ongoing funded research by providing shared infrastructure.

What is the intended impact of the DDRCC center approach?

The center approach is intended to help investigators work together more effectively, standardize and improve methods, and accelerate progress in areas relevant to digestive and liver diseases.

Where can applicants find the full funding announcement?

The full announcement and details were provided through NIH at: http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-11-022.html

Where is technical access support directed for this FOA?

Technical access support is routed through the NIH Office of Extramural Research webmaster contact listed in the notice.

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