Opportunity Information: Apply for RFA DK 16 019
Apply for RFA DK 16 019
- The HHS-NIH11 in the food and nutrition, health sector is offering a public funding opportunity titled "Silvio O. Conte Digestive Diseases Research Core Centers (P30)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847,.
- This funding opportunity was created on Feb 25, 2016 and posted on Feb 25, 2016.
- Applicants must submit their applications by Jul 07, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $750,000.00 in funding.
- The number of recipients for this funding is limited to 3 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
The Silvio O. Conte Digestive Diseases Research Core Centers (P30) funding opportunity (RFA DK 16 019) is a National Institutes of Health grant program administered through the Department of Health and Human Services, specifically NIH institute code HHS-NIH11, and it sits within the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) framework for supporting digestive and liver diseases research. The program is designed to strengthen and coordinate existing research activities by creating a centralized “core center” structure that serves multiple investigators. Rather than primarily funding individual research projects, a DDRCC supports shared infrastructure and services that make research groups more productive, more collaborative, and more likely to generate new ideas and interdisciplinary studies.
At the heart of this opportunity is the idea of building a research community that deliberately bridges basic science and clinical investigation. The FOA emphasizes bringing together investigators from both sides so that discoveries in fundamental biology can more quickly inform clinical questions, and clinical observations can, in turn, guide laboratory work. By putting these investigators into a single organized center with shared resources, the program aims to increase communication and coordination, reduce duplication of expensive capabilities, and raise the overall quality and efficiency of digestive and/or liver disease research at the applicant institution or consortium.
Each proposed DDRCC must be organized around a clear central theme. That theme is expected to reflect the real scientific focus of the participating center members and should unify the center’s activities, cores, and user community. Importantly, the theme must fall within NIDDK’s primary mission area and should not be primarily aligned with topics where another NIH Institute or Center would typically be considered the main funding home. In practice, that means applicants need to show that the center’s focus is meaningfully tied to NIDDK-supported digestive and liver diseases research and that the proposed center is not simply a broad biomedical core facility without a coherent digestive or liver disease emphasis.
The “core center” model is the main mechanism the FOA uses to create value. A DDRCC is expected to provide shared resources, services, and expertise that multiple funded investigators can access. These cores are intended to be cost-effective, to improve research productivity, and to create synergy across projects by enabling investigators to use common platforms, standardized methods, and specialized support that would be inefficient for each lab to maintain independently. The FOA also highlights that these shared resources should help spark new research directions and collaborations, which is a key rationale for funding P30 centers: they are meant to raise the collective capabilities of an investigator community, not just expand any single project.
From an administrative perspective, this is a discretionary grant using the NIH P30 center mechanism. The opportunity was posted and created on February 25, 2016, with an application closing date of July 7, 2016. The award ceiling listed is $750,000, and the announcement anticipated making about three awards. The activity category is listed under food and nutrition and health, and the CFDA numbers associated with the opportunity are 93.847. The program is open to a wide range of applicant organizations, including public and private institutions of higher education, state and local governments, federally recognized tribal governments and certain tribal organizations, public housing authorities/Indian housing authorities, nonprofit organizations (both 501(c)(3) and non-501(c)(3)), for-profit entities (other than small businesses), and small businesses, along with additional entities as clarified in the full eligibility text.
Overall, this FOA is best understood as a way for NIDDK to invest in shared scientific infrastructure and an organized research environment that amplifies the impact of ongoing digestive and liver disease research. Successful applicants would be expected to show a strong and active community of investigators, a compelling unifying theme within NIDDK’s mission, and a set of well-justified cores and center functions that clearly improve efficiency, collaboration, and scientific output across the participating research programs.
Frequently Asked Questions (FAQs)
What is the Silvio O. Conte Digestive Diseases Research Core Centers (P30) opportunity?
This funding opportunity supports Digestive Diseases Research Core Centers (DDRCCs) using the NIH P30 center mechanism. It is designed to strengthen and coordinate existing digestive and/or liver disease research activities by creating a centralized "core center" structure that serves multiple investigators through shared resources and services, rather than mainly funding individual research projects.
Which federal agency and NIH institute administer this program?
The opportunity is a National Institutes of Health (NIH) grant program under the U.S. Department of Health and Human Services (HHS), administered within the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The NIH institute code referenced is HHS-NIH11.
What is the main purpose of a DDRCC?
A DDRCC is intended to improve productivity, collaboration, coordination, and overall research quality in digestive and/or liver diseases by providing shared infrastructure, services, and expertise that multiple investigators can access. The goal is to reduce duplication of expensive capabilities and create synergy across projects by using common platforms and standardized methods.
Does this program primarily fund individual research projects?
No. The program emphasizes support for shared cores, infrastructure, and center services that enable and amplify the work of multiple funded investigators. It is meant to raise the collective capability of a research community rather than expand a single investigator's project.
What does "core center" mean in this context?
A "core center" is an organized structure that provides shared resources, services, and specialized expertise (often referred to as "cores") for use by multiple investigators. These shared cores are meant to be cost-effective and to make research groups more efficient and collaborative than if each lab tried to maintain the same capabilities independently.
What types of shared resources or services are expected to be supported?
The FOA emphasizes shared resources, services, and expertise that multiple funded investigators can use, designed to improve research productivity and cost-effectiveness. These shared resources should also encourage new collaborations, interdisciplinary studies, and new research directions.
How does the FOA encourage collaboration between basic science and clinical investigation?
The opportunity explicitly emphasizes bridging basic and clinical research by bringing investigators from both areas into one organized center with shared resources. The intent is to speed translation in both directions: basic discoveries informing clinical questions and clinical observations guiding laboratory research.
Is a central scientific theme required for the proposed center?
Yes. Each proposed DDRCC must be organized around a clear central theme that reflects the scientific focus of the participating members and unifies the center's activities, cores, and user community.
What should the central theme align with?
The theme must fall within NIDDK's primary mission area and should meaningfully tie to NIDDK-supported digestive and liver diseases research. The FOA indicates the theme should not be primarily aligned with topics that would typically be considered the main funding responsibility of another NIH Institute or Center.
Can the center be a broad biomedical core facility without a digestive or liver disease focus?
The information provided indicates that the proposed center should not simply be a broad biomedical core facility without a coherent digestive or liver disease emphasis. The center's theme and activities are expected to be unified and clearly within NIDDK's digestive and liver diseases mission area.
What is the grant mechanism used for this opportunity?
The program uses the NIH P30 center mechanism, and it is described as a discretionary grant under that mechanism.
What is the funding opportunity identifier listed?
The opportunity is referenced as RFA DK 16 019 for the Silvio O. Conte Digestive Diseases Research Core Centers (P30).
When was the opportunity posted and created?
The posting and creation date listed is February 25, 2016.
What is the application closing date stated in the information provided?
The application closing date stated is July 7, 2016.
What is the award ceiling for this opportunity?
The award ceiling listed is $750,000.
How many awards were anticipated?
The announcement anticipated making about three awards.
What activity category is associated with this opportunity?
The activity category is listed under food and nutrition and health.
What CFDA number is associated with this opportunity?
The CFDA number associated with the opportunity is 93.847.
Who is eligible to apply based on the information provided?
The program is open to a broad range of applicant organizations, including public and private institutions of higher education; state and local governments; federally recognized tribal governments and certain tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations (both 501(c)(3) and non-501(c)(3)); for-profit entities (other than small businesses); and small businesses, along with additional entities as clarified in the full eligibility text.
Is the program limited to a single institution, or can it involve multiple organizations?
The description references an applicant institution or consortium, which indicates the center can be organized at a single institution or through a consortium arrangement, as long as it supports a coordinated investigator community and shared core resources.
What are reviewers or program staff likely to look for in a successful DDRCC application (based on this description)?
Based on the information provided, successful applicants would be expected to demonstrate: (1) a strong and active community of investigators, (2) a compelling unifying theme within NIDDK's mission, and (3) well-justified cores and center functions that clearly improve efficiency, collaboration, coordination, and scientific output across participating research programs.
Why does the FOA emphasize shared cores and standardized platforms?
The FOA frames shared cores as a way to reduce duplication of expensive capabilities, increase efficiency, and improve research quality. Standardized methods and common platforms can make multiple projects more productive and comparable while supporting collaboration and interdisciplinary work.
What is the larger goal NIDDK is trying to achieve with this P30 investment?
The FOA is positioned as an investment in shared scientific infrastructure and an organized research environment that amplifies the impact of ongoing digestive and liver disease research. In other words, it aims to raise the overall capabilities and connectivity of a research community, not just fund isolated efforts.
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Applicants also applied for:
Applicants who have applied for this opportunity (RFA DK 16 019) also looked into and applied for these:
| Funding Opportunity |
|---|
| NIDDK Program Projects (P01) Apply for PAR 16 127 Funding Number: PAR 16 127 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: $6,250,000 |
| High Impact, Interdisciplinary Science in NIDDK Research Areas (RC2) Apply for PAR 16 126 Funding Number: PAR 16 126 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Early-Stage Preclinical Validation of Therapeutic Leads for Diseases of Interest to the NIDDK (R01) Apply for PAR 16 121 Funding Number: PAR 16 121 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Limited Competition: Small Grant Program for NIDDK K01/K08/K23 Recipients (R03) Apply for PAR 16 148 Funding Number: PAR 16 148 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: $50,000 |
| Advances in Polycystic Kidney Disease (R01) Apply for PA 16 159 Funding Number: PA 16 159 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Human Islet Distribution Coordinating Center (UC4) Apply for RFA DK 16 023 Funding Number: RFA DK 16 023 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: $1,300,000 |
| Limited Competition: Rare Diseases Clinical Research Network (RDCRN) Project Supplements for Clinical Trials to Repurpose Drugs in Collaboration with E-Rare Awardees (Admin Supp) Apply for PA 16 183 Funding Number: PA 16 183 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| NIDDK Short-Term Research Experience Program for Underrepresented Persons (STEP-UP) (R25) Apply for RFA DK 16 021 Funding Number: RFA DK 16 021 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| NIDDK Mentored Research Scientist Development Award (K01) Apply for PAR 16 211 Funding Number: PAR 16 211 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Nutrition Obesity Research Centers (NORCs) (P30) Apply for RFA DK 16 006 Funding Number: RFA DK 16 006 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Standardization of C-peptide and HbA1c Measurements Program (UC4) Apply for RFA DK 16 011 Funding Number: RFA DK 16 011 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: $350,000 |
| Diabetes Research Centers (P30) Apply for RFA DK 16 020 Funding Number: RFA DK 16 020 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Ancillary Studies to Identify Behavioral and/or Psychological Phenotypes Contributing to Obesity (R01) Apply for PAR 16 304 Funding Number: PAR 16 304 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Limited Competition for the Continuation of the Collaborative Islet Transplantation Registry (UC4) Apply for RFA DK 16 503 Funding Number: RFA DK 16 503 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Neurocognitive Effects of Glycemic Dysregulation in Type 1 Diabetes (DP3) Apply for RFA DK 16 007 Funding Number: RFA DK 16 007 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: $3,000,000 |
| Metabolic Contributions to the Neurocognitive Complications of Diabetes: Ancillary Studies (R01) Apply for PAR 16 333 Funding Number: PAR 16 333 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Pediatric Centers of Excellence in Nephrology (P50) Apply for RFA DK 16 032 Funding Number: RFA DK 16 032 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $750,000 |
| George M. O'Brien Kidney Research Core Centers (P30) Apply for RFA DK 16 031 Funding Number: RFA DK 16 031 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $750,000 |
| Promoting Organ and Tissue Donation Among Diverse Populations (R01) Apply for RFA DK 16 022 Funding Number: RFA DK 16 022 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $150,000 |
| Limited Competition for Data Coordinating Center (DCC) for NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) (U24) Apply for RFA DK 16 510 Funding Number: RFA DK 16 510 Agency: Department of Health and Human Services, National Institutes of Health Category: Food and Nutrition, Health Funding Amount: $1,062,000 |
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