Opportunity Information: Apply for PAR 16 323
Apply for PAR 16 323
- The HHS-NIH11 in the education, environment, health, income security and social services sector is offering a public funding opportunity titled "Small Research Grants for Establishing Basic Science-Clinical Collaborations to Understand Structural Birth Defects (R03)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.273, 93.279, 93.351, 93.853, 93.865,.
- This funding opportunity was created on Jun 10, 2016 and posted on Jun 10, 2016.
- Applicants must submit their applications by Sep 07, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $75,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
The Small Research Grants for Establishing Basic Science-Clinical Collaborations to Understand Structural Birth Defects (R03) opportunity (Funding Opportunity Number PAR-16-323) is a discretionary NIH grant program intended to help launch new, early-stage collaborations between basic science researchers and clinical teams focused on structural birth defects. The core aim is not to fund large, mature research programs, but to provide a modest amount of support that helps investigators from different disciplines begin working together, align their expertise, and generate initial data, shared resources, or proof-of-concept findings that can support future, larger applications. By emphasizing the "establishment" of collaborations, the program is essentially designed to lower the barrier for cross-disciplinary teams to form and start producing scientifically credible momentum in this area.
This FOA specifically targets interdisciplinary teams that bridge basic biology and clinical insight. It highlights that proposed teams may include developmental biologists, cell biologists, geneticists, genomicists, physician-scientists (including those with DVM/VMD degrees), clinicians, epidemiologists, biostatisticians, and bioinformaticists, among others. That mix signals the intent to encourage projects where mechanistic understanding of development and molecular pathways connects directly to clinical observation, patient-relevant data, or medically grounded research questions. In practice, the projects supported under this mechanism are typically expected to be tightly focused, feasible within a limited budget, and structured to demonstrate the value of the collaboration itself, for example by integrating clinical phenotyping with experimental models, linking genomic analysis to developmental mechanisms, or building pipelines that allow clinical and basic datasets to be analyzed together.
Administratively, the sponsoring agency is the U.S. Department of Health and Human Services (HHS), National Institutes of Health (NIH), listed as HHS-NIH11. The funding instrument is a grant under an R03 mechanism, which is commonly used by NIH for small research grants. The posted and creation dates for the opportunity are June 10, 2016, and the listed application closing date in the provided source is September 7, 2019 (with the original and current closing dates matching). The award ceiling is listed as $75,000, indicating the maximum amount available per award under this announcement as presented in the source data.
Eligibility is broad and includes a wide range of public and private organizations. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; Native American tribal governments (federally recognized) and tribal organizations (including those not federally recognized); public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (excluding institutions of higher education in those categories as specified); for-profit organizations other than small businesses; small businesses; and other entities as allowed under additional NIH eligibility guidance referenced in the full announcement. The FOA is also associated with multiple CFDA numbers (93.113, 93.121, 93.273, 93.279, 93.351, 93.853, 93.865), reflecting that the funding may align with several NIH program areas tied to health and biomedical research.
Overall, this grant opportunity is best understood as seed funding intended to catalyze new basic science-clinical partnerships aimed at understanding structural birth defects, with a strong emphasis on interdisciplinary integration, early collaborative development, and producing foundational outputs that can support longer-term, larger-scale studies.
Frequently Asked Questions (FAQs)
What is the name of this grant opportunity?
The opportunity is titled Small Research Grants for Establishing Basic Science-Clinical Collaborations to Understand Structural Birth Defects (R03).
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is PAR-16-323.
Which agency sponsors this funding opportunity?
The sponsoring agency is the U.S. Department of Health and Human Services (HHS), National Institutes of Health (NIH), listed as HHS-NIH11.
What type of funding mechanism is this?
This is an NIH R03 mechanism, which is commonly used for small research grants.
What is the main purpose of this R03 opportunity?
The core purpose is to provide seed funding to help launch new, early-stage collaborations between basic science researchers and clinical teams focused on structural birth defects. The emphasis is on establishing the collaboration and generating early momentum rather than supporting a large, mature research program.
Is this grant meant to fund large, long-term research programs?
No. The opportunity is described as intended to provide a modest amount of support to start interdisciplinary collaborations, align expertise, and produce initial outputs that can support future, larger applications.
What kinds of outcomes are expected from projects funded under this announcement?
Projects are generally expected to produce foundational outputs that demonstrate the value of the new collaboration, such as initial data, shared resources, or proof-of-concept findings that could strengthen future applications for larger-scale funding.
What research area does this FOA focus on?
The FOA focuses on research to better understand structural birth defects, specifically through collaborations that connect basic developmental and molecular science with clinical insight and patient-relevant questions.
What does "establishing" a collaboration mean in the context of this FOA?
It means the program is designed to lower the barrier for cross-disciplinary teams to form and begin working together, aligning methods and perspectives and generating early scientific outputs that show the collaboration is productive and credible.
What kinds of interdisciplinary teams does the FOA encourage?
The FOA highlights teams that bridge basic biology and clinical expertise. It specifically mentions that teams may include (among others): developmental biologists, cell biologists, geneticists, genomicists, physician-scientists (including DVM/VMD), clinicians, epidemiologists, biostatisticians, and bioinformaticists.
Are clinician-basic science partnerships specifically required or strongly encouraged?
Based on the description provided, the FOA is specifically intended to support basic science-clinical collaborations, with a clear emphasis on integrating mechanistic research and clinical insight in a joint effort focused on structural birth defects.
What types of project designs seem to fit this FOA?
The FOA points to tightly focused, feasible projects that demonstrate interdisciplinary integration, such as: integrating clinical phenotyping with experimental models, linking genomic analyses to developmental mechanisms, or building pipelines that allow clinical and basic datasets to be analyzed together.
What is the maximum award amount (award ceiling) listed for this opportunity?
The award ceiling is listed as $75,000, which indicates the maximum amount available per award under the announcement as presented in the source information.
When was this opportunity posted and created?
The posted date and creation date are listed as June 10, 2016.
What is the application closing date shown in the provided information?
The application closing date listed in the provided source is September 7, 2019, with the original and current closing dates shown as matching.
What kinds of organizations are eligible to apply?
Eligibility is broad and includes many public and private organization types, including: state governments; county governments; city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations (including those not federally recognized); public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (with exclusions as specified for institutions of higher education in those categories); for-profit organizations other than small businesses; small businesses; and other entities as allowed under NIH eligibility guidance referenced in the full announcement.
Are small businesses eligible to apply?
Yes. The eligibility list explicitly includes small businesses.
Are for-profit organizations eligible to apply?
Yes. The eligibility list includes for-profit organizations other than small businesses, and it also includes small businesses.
Are nonprofit organizations eligible to apply?
Yes. The eligibility list includes nonprofit organizations with or without 501(c)(3) status, with the note that certain exclusions apply as specified in the eligibility wording provided (particularly regarding institutions of higher education in those categories).
Are colleges and universities eligible to apply?
Yes. Both public and state-controlled institutions of higher education and private institutions of higher education are listed as eligible applicants.
Are government entities eligible to apply?
Yes. Multiple government categories are listed as eligible, including state, county, city or township, and special district governments, as well as independent school districts.
Are tribal governments and tribal organizations eligible?
Yes. The eligibility list includes Native American tribal governments (federally recognized) and tribal organizations, including those not federally recognized.
Are public housing authorities eligible?
Yes. The eligibility list includes public housing authorities/Indian housing authorities.
What CFDA numbers are associated with this FOA?
The FOA is associated with multiple CFDA numbers: 93.113, 93.121, 93.273, 93.279, 93.351, 93.853, 93.865.
What do the multiple CFDA numbers suggest?
Based on the provided description, the multiple CFDA numbers indicate the funding may align with several NIH program areas tied to health and biomedical research.
What is the overall intent of this opportunity in plain terms?
This opportunity is best understood as seed funding to help basic scientists and clinicians start working together on structural birth defects, build early shared progress (data/resources/proof-of-concept), and position the team for future, larger-scale funding.
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