Opportunity Information: Apply for CDC RFA PS14 1401
Apply for CDC RFA PS14 1401
- The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "STD Laboratory based Surveillance and Gonococcal Isolate Surveillance Project (GISP)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.977 Preventive Health ServicesSexually Transmitted Diseases Control Grants.
- This funding opportunity was created on May 14, 2013 and posted on May 14, 2013.
- Applicants must submit their applications by Aug 13, 2013 Letter of Intent Deadline Date June 14, 2013 Application Deadline Date August 13th, 2013, 1159 p.m. U.S. Eastern Standard Time, on www.grants.gov. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $7,500,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- The number of recipients for this funding is limited to 5 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
- 1. Eligible Applicants Limited competition Eligible awardees must be located in the United States and must have the necessary infrastructure in place to perform the activities required for this national surveillance program. In addition, awardees must have the expertise and experience needed to successfully complete the required functions. Eligible applicants that can apply for this FOA are listed below For profit organizations (other than small business) Hospitals Nonprofit with 501C3 IRS status (other than institution of higher education) Nonprofit without 501C3 IRS status (other than institution of higher education) Political subdivisions of States (in consultation with States) Research institutions (that will perform activities deemed as non research) State and local governments or their Bona Fide Agents (this includes the District of Columbia, the Commonwealth of Puerto Rico, the Virgin Islands, the Commonwealth of the Northern Marianna Islands, American Samoa, Guam, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau). Universities
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Opportunity Summary:
The CDC funding opportunity CDC RFA PS14-1401, titled "STD Laboratory based Surveillance and Gonococcal Isolate Surveillance Project (GISP)," was a discretionary cooperative agreement designed to strengthen national laboratory capacity for sexually transmitted disease surveillance, with a particular focus on gonorrhea and antimicrobial resistance. The core goal was to build and maintain a coordinated network of U.S.-based reference laboratories that could provide specialized, laboratory-based testing and surveillance services for sexually transmitted pathogens. While the network could support additional STD surveillance activities over time, the main function centered on delivering timely antimicrobial susceptibility testing for Neisseria gonorrhoeae isolates collected through GISP sentinel sites following the established GISP protocol.
A key feature of this program was its emphasis on monitoring antibiotic resistance in gonorrhea, which is a major public health concern because N. gonorrhoeae has a long history of developing resistance to multiple drug classes. By funding a small number of reference labs to perform standardized, high-quality susceptibility testing on isolates collected across sentinel sites, CDC aimed to generate consistent, actionable data that could inform treatment guidelines, detect emerging resistance patterns early, and support rapid public health responses. In practice, awardees were expected to function as reference laboratories within the national network, meaning they needed the infrastructure, expertise, and operational readiness to handle specialized testing, manage laboratory workflows tied to ongoing surveillance, and produce results within timelines appropriate for public health decision-making.
The FOA also made it clear that funded laboratory principal investigators would play an important advisory and technical role beyond routine testing. These GISP lab PIs were expected to serve as consultative resources to CDC on laboratory-based public health STD surveillance, the clinical and laboratory dimensions of gonorrhea, and the evolving landscape of antimicrobial resistance in N. gonorrhoeae. This consultative expectation reflects the cooperative agreement structure, where recipients typically collaborate closely with the federal agency, contributing technical insight and helping shape surveillance strategy rather than operating in a purely hands-off grant arrangement.
In terms of scale and structure, CDC anticipated making five awards under this opportunity, with an estimated total funding level of $7.5 million. The listed award ceiling was $500,000, and there was no cost sharing or matching requirement. The program fell under CFDA 93.977, "Preventive Health Services - Sexually Transmitted Diseases Control Grants," aligning it with broader STD prevention and control efforts rather than research-focused funding. The activity category was labeled "Health," and the funded work was framed as surveillance and public health laboratory services, including work by research institutions as long as activities were deemed non-research in nature.
Eligibility was described as a limited competition, with awardees required to be located in the United States and already equipped with the necessary infrastructure to carry out the national surveillance functions. CDC emphasized that applicants must have demonstrated expertise and experience to successfully complete the required work, underscoring that this was not a capacity-building grant for labs starting from scratch but rather support for established entities able to deliver reference-level testing. Eligible applicant types were broad and included for-profit organizations (other than small business), hospitals, nonprofits with or without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories), political subdivisions of states (in consultation with states), state and local governments and their bona fide agents (including U.S. territories and freely associated states listed in the announcement), universities, and research institutions performing non-research activities.
Administratively, the opportunity was posted on May 14, 2013, with a letter of intent deadline of June 14, 2013, and an application deadline of August 13, 2013 at 11:59 p.m. Eastern Time via Grants.gov. The archive date was September 12, 2013, indicating it is no longer active. For access issues related to the full announcement, the notice directed applicants to contact the CDC Procurement and Grants Office Technical Information Management Section (TIMS) at 770-488-2700. Overall, the FOA reflects CDC's strategy of using a sentinel surveillance model supported by a small, high-capacity reference laboratory network to track gonococcal antimicrobial susceptibility trends reliably and quickly, providing the evidence base needed to protect the effectiveness of available treatments and guide national STD control actions.
FAQs: CDC RFA PS14-1401 - STD Laboratory based Surveillance and Gonococcal Isolate Surveillance Project (GISP)
What is CDC RFA PS14-1401?
CDC RFA PS14-1401 is a CDC discretionary cooperative agreement titled "STD Laboratory based Surveillance and Gonococcal Isolate Surveillance Project (GISP)." It was designed to strengthen national laboratory capacity for sexually transmitted disease (STD) surveillance, with a primary focus on gonorrhea and antimicrobial resistance monitoring.
What is the main purpose of this funding opportunity?
The core purpose was to build and maintain a coordinated U.S.-based network of reference laboratories capable of providing specialized laboratory testing and surveillance services for sexually transmitted pathogens, with the central function being timely antimicrobial susceptibility testing for Neisseria gonorrhoeae isolates collected through GISP sentinel sites.
What is GISP in this context?
GISP refers to the Gonococcal Isolate Surveillance Project, which uses a sentinel surveillance model. Under this program, N. gonorrhoeae isolates are collected at sentinel sites and then tested by funded reference laboratories following the established GISP protocol.
What organism and public health issue does the program emphasize?
The program emphasizes Neisseria gonorrhoeae (the bacterium that causes gonorrhea) and the public health threat of antimicrobial resistance. A key rationale is that N. gonorrhoeae has a long history of developing resistance to multiple drug classes.
What kinds of activities were awardees expected to perform?
Awardees were expected to function as reference laboratories within a national network. This included performing standardized, high-quality antimicrobial susceptibility testing on gonorrhea isolates from GISP sentinel sites, managing surveillance-related laboratory workflows, and producing results within timelines suitable for public health decision-making.
Was this opportunity intended to help labs build capacity from the ground up?
No. CDC emphasized that applicants needed to already have the necessary infrastructure, expertise, and operational readiness. The announcement stressed demonstrated expertise and experience, indicating the opportunity was meant to support established entities rather than new labs starting from scratch.
How would the data generated by this program be used?
The susceptibility testing data were intended to be consistent and actionable so they could inform treatment guidelines, detect emerging resistance patterns early, and support rapid public health responses.
What role did funded laboratory principal investigators (PIs) play beyond routine testing?
Funded laboratory PIs were expected to serve as consultative resources to CDC on laboratory-based public health STD surveillance, the clinical and laboratory dimensions of gonorrhea, and the evolving antimicrobial resistance landscape in N. gonorrhoeae.
What does the cooperative agreement structure imply for recipient involvement?
The cooperative agreement structure implied closer collaboration with CDC than a typical hands-off grant. Recipients were expected to contribute technical insight and help inform surveillance strategy, in addition to performing the required laboratory surveillance functions.
How many awards did CDC anticipate making?
CDC anticipated making five awards under this funding opportunity.
What was the estimated total funding level for the opportunity?
The estimated total funding level was $7.5 million.
What was the award ceiling?
The listed award ceiling was $500,000.
Was cost sharing or matching required?
No. The opportunity specified that there was no cost sharing or matching requirement.
What CFDA program was associated with this opportunity?
The opportunity fell under CFDA 93.977, "Preventive Health Services - Sexually Transmitted Diseases Control Grants."
What was the activity category?
The activity category for this opportunity was labeled "Health."
Were the funded activities considered research?
The funded work was framed as surveillance and public health laboratory services. The announcement indicated that research institutions could participate as long as the supported activities were deemed non-research in nature.
Who was eligible to apply?
Eligibility was described as a limited competition. Applicants had to be located in the United States and already equipped to carry out national surveillance functions, with demonstrated expertise and experience. Eligible applicant types included for-profit organizations (other than small business), hospitals, nonprofits with or without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories), political subdivisions of states (in consultation with states), state and local governments and their bona fide agents (including U.S. territories and freely associated states listed in the announcement), universities, and research institutions performing non-research activities.
Did the announcement restrict eligibility to U.S.-based entities?
Yes. Awardees were required to be located in the United States.
When was the opportunity posted?
The opportunity was posted on May 14, 2013.
Was a letter of intent required, and when was it due?
The announcement listed a letter of intent deadline of June 14, 2013.
When was the application deadline?
The application deadline was August 13, 2013 at 11:59 p.m. Eastern Time, and applications were to be submitted via Grants.gov.
Is this funding opportunity still active?
No. The archive date was September 12, 2013, indicating the opportunity is no longer active.
Where were applications submitted?
Applications were submitted through Grants.gov.
Who should an applicant contact if they had trouble accessing the full announcement?
The notice directed applicants with access issues to contact the CDC Procurement and Grants Office Technical Information Management Section (TIMS) at 770-488-2700.
What broader CDC strategy does this FOA reflect?
The FOA reflects CDC's use of a sentinel surveillance model supported by a small, high-capacity reference laboratory network to track gonococcal antimicrobial susceptibility trends quickly and reliably, helping protect treatment effectiveness and guide national STD control actions.
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