Opportunity Information: Apply for PAS 10 046
Apply for PAS 10 046
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Stimulating Hematology Investigation New Endeavors (SHINE) (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on Dec 4, 2009 and posted on Dec 4, 2009.
- Applicants must submit their applications by Jan 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,250,000.00 to eligible and selected applicants.
- Eligible applicants include: Small businesses Private institutions of higher education Public housing authorities/Indian housing authorities For profit organizations other than small businesses Independent school districts City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) County governments Special district governments State governments Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Stimulating Hematology Investigation New Endeavors (SHINE) (R01) funding opportunity (PAS 10-046) is a National Institutes of Health (NIH) initiative led by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) designed to accelerate innovative, high-quality research in hematology that aligns with NIDDKs mission. The main goal is to push the field forward by encouraging investigator-initiated projects that address especially timely needs and promising opportunities in both basic and translational hematology. In other words, the program is meant to help researchers tackle emerging or particularly important questions in blood-related biology and disease where progress seems achievable and impactful.
SHINE uses the NIH R01 mechanism, which is the standard, full-scale Research Project Grant meant to support well-developed research ideas with strong scientific rationale and a clear plan for execution. Because it is an R01, applicants are generally expected to propose a substantial and coherent project with defined aims, rigorous methods, and a convincing approach for generating meaningful results. The emphasis on basic and translational work signals that applications can range from fundamental discovery science (for example, mechanisms of blood cell development or regulation) to research that bridges toward clinical relevance (for example, studies that clarify disease pathways, identify therapeutic targets, or develop enabling tools that may later support clinical studies).
A key feature of SHINE is that the specific topic areas of interest are not fixed forever. NIDDK indicates that the targeted hematology research areas supported under SHINE will be updated annually through the NIH Guide to Grants and Contracts. This structure allows the program to stay responsive to scientific advances and shifting gaps in knowledge, and it also means prospective applicants should check the most current NIH Guide notices for the latest list of priority topics and any updated expectations.
In terms of funding scope, NIDDK set aside an estimated total of $1,250,000 in fiscal year 2010 to support approximately 3 to 4 awards under this announcement, and these awards are described as being in addition to projects funded under NIDDKs regular funding policies. Funding in later years was not guaranteed and would depend on the availability of funds, with updates to be provided through NIH Guide notices. The opportunity is categorized as discretionary funding and uses the grant funding instrument type. The CFDA listing tied to the opportunity is 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), reflecting the administering institutes broader mission area even though the scientific focus here is hematology. The opportunity did not require cost sharing or matching.
Eligibility is broad and includes a wide range of organization types. Eligible applicants include public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status), for-profit organizations (including small businesses and other for-profits), and multiple levels of government (state, county, city/township, special district), as well as independent school districts and certain housing authorities. The eligibility list also explicitly includes several institution and community categories often highlighted in federal opportunities, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Native American tribal governments (federally recognized and other than federally recognized), and U.S. territories or possessions. Notably, non-U.S. entities (foreign organizations) and regional organizations are also included, indicating that international or multinational participation could be permissible under the terms described, subject to NIH policies and the specific FOA requirements.
Administratively, the opportunity was posted and created on December 4, 2009. The original closing date and the listed current closing date were January 7, 2013, and the archive date was February 7, 2013, meaning it is no longer active as a current competition but remains part of the historical record. Applicants or interested parties were directed to the full announcement page hosted on the NIH grants site, and technical access issues were routed to the NIH Office of Extramural Research (OER) webmaster contact.
Frequently Asked Questions (FAQs)
What is the SHINE (R01) funding opportunity?
Stimulating Hematology Investigation New Endeavors (SHINE) (R01) is an NIH funding opportunity (PAS 10-046) led by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to accelerate innovative, high-quality research in hematology that aligns with NIDDK's mission.
What is the main goal of SHINE?
The main goal is to move the hematology field forward by supporting investigator-initiated projects that address timely needs and promising opportunities in both basic and translational hematology, especially where progress is considered achievable and impactful.
Which NIH institute leads this initiative?
The initiative is led by NIDDK (National Institute of Diabetes and Digestive and Kidney Diseases), within the National Institutes of Health (NIH).
What funding mechanism does SHINE use?
SHINE uses the NIH R01 mechanism, which is the standard full-scale Research Project Grant intended to support well-developed research projects with strong scientific rationale and a clear execution plan.
What kinds of projects are expected under an R01 for this opportunity?
Because this is an R01, applicants are generally expected to propose a substantial, coherent project with defined aims, rigorous methods, and a convincing approach for producing meaningful results.
Does SHINE support basic research, translational research, or both?
Both. The opportunity emphasizes basic and translational hematology. This can include fundamental discovery science (such as mechanisms of blood cell development or regulation) as well as work that bridges toward clinical relevance (such as clarifying disease pathways, identifying therapeutic targets, or developing enabling tools that may later support clinical studies).
Are the targeted scientific topic areas fixed?
No. NIDDK indicated that the targeted hematology research areas supported under SHINE would be updated annually through notices in the NIH Guide to Grants and Contracts.
Where would applicants have found the most up-to-date list of SHINE priority topics?
Applicants were expected to check the NIH Guide to Grants and Contracts for the most current notices describing priority topics and any updated expectations for SHINE.
How much funding was set aside for SHINE (FY 2010)?
NIDDK estimated a total of $1,250,000 in fiscal year 2010 to support approximately 3 to 4 awards under this announcement.
How many awards were expected?
Approximately 3 to 4 awards were anticipated for FY 2010 based on the set-aside amount described.
Were future-year funds guaranteed?
No. Funding in later years was not guaranteed and depended on the availability of funds, with updates to be provided through NIH Guide notices.
Were SHINE awards in addition to NIDDK's regular funding?
Yes. The awards under this announcement were described as being in addition to projects funded under NIDDK's regular funding policies.
What type of funding is this considered?
The opportunity was categorized as discretionary funding and used the grant funding instrument type.
What CFDA number is associated with this opportunity?
The CFDA listing tied to the opportunity is 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research).
Why is the CFDA tied to diabetes, digestive, and kidney diseases if the focus is hematology?
The CFDA reflects the administering institute's broader mission area (NIDDK), even though the SHINE scientific focus described here is hematology.
Was cost sharing or matching required?
No. The opportunity did not require cost sharing or matching.
Who was eligible to apply?
Eligibility was broad and included many organization types: public and private institutions of higher education; nonprofit organizations (with and without 501(c)(3) status); for-profit organizations (including small businesses and other for-profits); and multiple levels of government (state, county, city/township, special district), as well as independent school districts and certain housing authorities.
Are minority-serving institutions specifically included in the eligibility list?
Yes. The eligibility list explicitly includes categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), and additional community and institution categories commonly cited in federal opportunities.
Are tribal governments eligible?
Yes. Native American tribal governments (federally recognized and other than federally recognized) were included in the eligibility list.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions were included as eligible applicants.
Are non-U.S. (foreign) organizations eligible?
Yes. The eligibility list includes non-U.S. entities (foreign organizations) and regional organizations, indicating international or multinational participation could be permissible under the terms described, subject to NIH policies and the specific FOA requirements.
When was this opportunity posted and created?
The opportunity was posted and created on December 4, 2009.
What were the closing dates for this opportunity?
The original closing date and the listed current closing date were both January 7, 2013.
Is this funding opportunity still active?
No. The archive date was February 7, 2013, which indicates it is no longer active as a current competition and remains part of the historical record.
Where were applicants directed for the full announcement?
Applicants or interested parties were directed to the full announcement page hosted on the NIH grants site.
Who was listed as the contact for technical access issues?
Technical access issues were routed to the NIH Office of Extramural Research (OER) webmaster contact.
What is the FOA identifier for SHINE?
The funding opportunity is identified as PAS 10-046.
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