Opportunity Information: Apply for PAS 16 033
Apply for PAS 16 033
- The HHS-NIH11 in the food and nutrition, health sector is offering a public funding opportunity titled "Stimulating Hematology Investigation: New Endeavors (SHINE) (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847,.
- This funding opportunity was created on Nov 06, 2015 and posted on Nov 06, 2015.
- Applicants must submit their applications by Jan 07, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
The Stimulating Hematology Investigation: New Endeavors (SHINE) (R01) funding opportunity (PAS 16-033) is an NIH discretionary research grant program run by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) within HHS/NIH. Its main purpose is to spark innovative, high-quality hematology research that aligns closely with NIDDKs mission, with a particular emphasis on projects that are both scientifically strong and positioned to move the field forward in areas where the timing is right for rapid progress. In practical terms, the program is meant to encourage investigator-initiated ideas that bring fresh approaches, new directions, or underexplored concepts to important questions in blood-related biology and disease, especially where basic discoveries can plausibly connect to translational pathways.
A defining feature of SHINE is that it targets specific topic areas in basic and translational hematology that NIDDK considers especially urgent or promising at a given time. Rather than being a permanently fixed list, these focus areas are designed to evolve. NIDDK updates the supported research topic areas on an ongoing basis, with annual updates communicated through the NIH Guide to Grants and Contracts. For applicants, that means the core mechanism is an R01 research project grant, but the best-fitting applications are those that clearly map onto the current SHINE-highlighted scientific priorities at the time of submission, demonstrating why the proposed work is timely and how it addresses an identified gap or opportunity.
The award uses the NIH R01 mechanism, which generally supports hypothesis-driven or goal-directed research projects led by a principal investigator (or multiple PIs, when appropriate). Although the source data does not specify an award ceiling or an expected number of awards, the structure implies standard NIH competitive peer review and NIDDK programmatic consideration, with funding decisions reflecting scientific merit, relevance to NIDDK priorities in hematology, and fit to the SHINE topic areas in effect for that year. The activity category is listed under health-related research (with a broader classification referencing food and nutrition and health), and the associated CFDA numbers are 93.847 (and also referenced is 93.847 in the listing).
Eligibility is broad and reflects typical NIH policy for R01 opportunities. Eligible applicants include public-sector entities such as state, county, city or township governments, special district governments, and independent school districts, as well as public and state-controlled institutions of higher education. Tribal entities are eligible, including federally recognized Native American tribal governments and other Native American tribal organizations. The opportunity is also open to public housing authorities/Indian housing authorities, nonprofit organizations both with and without 501(c)(3) status (excluding higher education institutions where specified), private institutions of higher education, for-profit organizations (other than small businesses), and small businesses. The listing also notes an "Others" category, indicating there may be additional eligibility details in the full announcement text.
Administratively, the opportunity was posted on November 6, 2015 (creation date and posted date both listed as Nov 06, 2015). The closing date shown is January 7, 2019 (original and current closing dates match in the provided record). Overall, SHINE is best understood as a focused, priority-driven pathway within the standard R01 framework, intended to channel strong investigator-led hematology proposals into areas NIDDK has identified as ripe for meaningful advances, with those priority areas refreshed regularly to keep pace with scientific and clinical opportunities.
Frequently Asked Questions (FAQs)
What is the SHINE (R01) funding opportunity?
Stimulating Hematology Investigation: New Endeavors (SHINE) (R01) is an NIH discretionary research grant program (PAS 16-033) administered by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) within HHS/NIH. It uses the NIH R01 research project grant mechanism to support investigator-initiated hematology research that aligns with NIDDK's mission.
Which agency runs SHINE?
The program is run by NIDDK, an institute within the National Institutes of Health (NIH), which is part of the U.S. Department of Health and Human Services (HHS).
What is the main purpose of SHINE?
The main purpose is to stimulate innovative, high-quality hematology research that fits NIDDK priorities, with particular emphasis on projects that are well-positioned to move the field forward when the timing is right for rapid progress.
What types of research does SHINE aim to encourage?
SHINE is intended to encourage investigator-initiated ideas that bring fresh approaches, new directions, or underexplored concepts to important questions in blood-related biology and disease, especially where basic discoveries can plausibly connect to translational pathways.
Is SHINE focused on basic research, translational research, or both?
Based on the provided description, SHINE supports both basic and translational hematology research, with an emphasis on topic areas NIDDK considers urgent or especially promising and where progress could be timely.
What makes SHINE different from a general R01 opportunity?
SHINE is described as a focused, priority-driven pathway within the standard R01 framework. A defining feature is that it targets specific topic areas in basic and translational hematology that NIDDK highlights as urgent or promising at a given time, rather than being open-ended across all hematology topics.
How are SHINE research topic areas determined?
The supported topic areas are set by NIDDK and are designed to evolve over time. They are not described as a permanently fixed list.
How often are SHINE topic areas updated?
NIDDK updates the supported research topic areas on an ongoing basis, with annual updates communicated through the NIH Guide to Grants and Contracts.
Where are updates to SHINE topic areas communicated?
Annual updates are communicated through the NIH Guide to Grants and Contracts.
What should an applicant emphasize to be a strong fit for SHINE?
The best-fitting applications are those that clearly map onto the current SHINE-highlighted scientific priorities at the time of submission and explain why the proposed work is timely and addresses an identified gap or opportunity.
What grant mechanism does SHINE use?
SHINE uses the NIH R01 research project grant mechanism.
What does the R01 mechanism generally support in this program?
The R01 mechanism generally supports hypothesis-driven or goal-directed research projects led by a principal investigator, or multiple principal investigators when appropriate.
Does the opportunity specify a maximum award amount (award ceiling)?
No award ceiling is specified in the provided information.
Does the opportunity specify how many awards will be made?
No expected number of awards is specified in the provided information.
How are funding decisions described for SHINE?
The provided information indicates a structure consistent with standard NIH competitive peer review and NIDDK programmatic consideration. Funding decisions are described as reflecting scientific merit, relevance to NIDDK priorities in hematology, and fit to the SHINE topic areas in effect for that year.
What is the activity category for this opportunity?
The activity category is listed under health-related research, with a broader classification referencing food and nutrition and health.
What is the CFDA number associated with SHINE?
The associated CFDA number provided is 93.847 (also referenced as 93.847 in the listing).
Who is eligible to apply?
Eligibility is broad and reflects typical NIH policy for R01 opportunities. Eligible applicants include a wide range of public and private entities, including governments, universities, nonprofits, and certain businesses, as listed in the opportunity record.
Are state and local governments eligible?
Yes. Eligible public-sector entities include state governments, county governments, city or township governments, special district governments, and independent school districts.
Are colleges and universities eligible?
Yes. Public and state-controlled institutions of higher education and private institutions of higher education are listed as eligible.
Are tribal entities eligible to apply?
Yes. Federally recognized Native American tribal governments and other Native American tribal organizations are listed as eligible.
Are public housing authorities eligible?
Yes. Public housing authorities and Indian housing authorities are listed as eligible.
Are nonprofit organizations eligible?
Yes. Nonprofit organizations with 501(c)(3) status and nonprofit organizations without 501(c)(3) status are listed as eligible (excluding higher education institutions where specified).
Are for-profit organizations eligible?
Yes. For-profit organizations (other than small businesses) are listed as eligible, and small businesses are also listed as eligible.
What does the listing mean by an "Others" eligibility category?
The record notes an "Others" category, indicating there may be additional eligibility details in the full announcement text beyond the categories summarized in the provided information.
When was this opportunity posted?
The opportunity was posted on November 6, 2015 (the creation date and posted date are both listed as Nov 06, 2015).
What is the closing date shown for this opportunity?
The closing date shown is January 7, 2019 (the original and current closing dates match in the provided record).
What does PAS 16-033 refer to?
PAS 16-033 is the identifier provided for this SHINE funding opportunity in the supplied information.
How should SHINE be understood overall?
SHINE is described as a focused, priority-driven pathway within the standard NIH R01 framework. It is intended to channel strong investigator-led hematology proposals into NIDDK-identified areas considered ripe for meaningful advances, with those priority areas refreshed regularly to keep pace with scientific and clinical opportunities.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAS 16 033) also looked into and applied for these:
| Funding Opportunity |
|---|
| Improving Diabetes Management in Pre-teens, Adolescents and/or Young Adults with Type 1 Diabetes (DP3) Apply for RFA DK 16 001 Funding Number: RFA DK 16 001 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: $1,400,000 |
| Developmental Centers for Interdisciplinary Research in Benign Urology (P20) Apply for RFA DK 16 012 Funding Number: RFA DK 16 012 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: $200,000 |
| Advancing Erythroid Cell Biology (R01) Apply for PA 16 039 Funding Number: PA 16 039 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| SBIR/STTR Commercialization Readiness Pilot (CRP) Program: Technical Assistance and Late Stage Development (SB1) Apply for PAR 16 027 Funding Number: PAR 16 027 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Understanding Barriers and Facilitators to Type 1 Diabetes Management in Adults (DP3) Apply for RFA DK 16 002 Funding Number: RFA DK 16 002 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: $2,500,000 |
| Elucidating HIV and HIV-treatment Associated Metabolic/Endocrine Dysfunction (R01) Apply for RFA DK 16 014 Funding Number: RFA DK 16 014 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: $500,000 |
| Innovative Research in HIV in Kidney, Urology, and Hematology (R01) Apply for RFA DK 16 015 Funding Number: RFA DK 16 015 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: $500,000 |
| George M. O'Brien Urology Cooperative Research Centers Program (U54) Apply for RFA DK 16 013 Funding Number: RFA DK 16 013 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: $1,000,000 |
| Development of New Technologies and Bioengineering Solutions for the Advancement of Cell Replacement Therapies for Type 1 Diabetes (R43/R44) Apply for RFA DK 16 004 Funding Number: RFA DK 16 004 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Psychosocial and Behavioral Mechanisms in Bariatric Surgery (R01) Apply for RFA DK 16 017 Funding Number: RFA DK 16 017 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: $500,000 |
| Small Grants for New Investigators to Promote Diversity in Health-Related Research (R21) Apply for PAR 16 064 Funding Number: PAR 16 064 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: $125,000 |
| Limited Competition for the Continuation of the Scientific Data Research Center (SDRC) for the NIDDK Gastroparesis Consortium (U24) Apply for RFA DK 16 507 Funding Number: RFA DK 16 507 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: $1,000,000 |
| Clinical Centers to Investigate the Pathogenesis, Etiology, and Treatment of Gastroparesis through the NIDDK Gastroparesis Consortium (U01) Apply for RFA DK 16 010 Funding Number: RFA DK 16 010 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: $250,000 |
| Silvio O. Conte Digestive Diseases Research Core Centers (P30) Apply for RFA DK 16 019 Funding Number: RFA DK 16 019 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: $750,000 |
| NIDDK Program Projects (P01) Apply for PAR 16 127 Funding Number: PAR 16 127 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: $6,250,000 |
| High Impact, Interdisciplinary Science in NIDDK Research Areas (RC2) Apply for PAR 16 126 Funding Number: PAR 16 126 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Early-Stage Preclinical Validation of Therapeutic Leads for Diseases of Interest to the NIDDK (R01) Apply for PAR 16 121 Funding Number: PAR 16 121 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Limited Competition: Small Grant Program for NIDDK K01/K08/K23 Recipients (R03) Apply for PAR 16 148 Funding Number: PAR 16 148 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: $50,000 |
| Advances in Polycystic Kidney Disease (R01) Apply for PA 16 159 Funding Number: PA 16 159 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: Case Dependent |
| Human Islet Distribution Coordinating Center (UC4) Apply for RFA DK 16 023 Funding Number: RFA DK 16 023 Agency: HHS-NIH11 Category: Food and Nutrition, Health Funding Amount: $1,300,000 |
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