Opportunity Information: Apply for PAR 16 278
Apply for PAR 16 278
- The HHS-NIH11 in the education, health sector is offering a public funding opportunity titled "Stimulating Innovations in Behavioral Intervention Research for Cancer Prevention and Control (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.399,.
- This funding opportunity was created on May 23, 2016 and posted on May 23, 2016.
- Applicants must submit their applications by May 07, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
Stimulating Innovations in Behavioral Intervention Research for Cancer Prevention and Control (R21) (PAR 16-278) is a National Institutes of Health (NIH), U.S. Department of Health and Human Services funding opportunity designed to push behavioral intervention science in new directions for cancer prevention and control. The central goal is to support early-stage, high-impact research that develops innovative interventions to improve cancer-related health behaviors, with an explicit focus on relevance and effectiveness across diverse racial and ethnic populations. The mechanism is an R21 exploratory/developmental grant, which typically fits projects that are testing bold ideas, piloting promising approaches, or generating the kind of preliminary evidence needed for a larger follow-on study.
The FOA emphasizes four main research thrusts. First, it encourages investigators to test new theories and conceptual frameworks that can better explain and change cancer-related behaviors, especially where existing models have not adequately addressed real-world complexity, culture, context, or persistent disparities. Second, it calls for the development and evaluation of novel strategies to improve behaviors linked to cancer risk, survivorship, and outcomes, including creative intervention content, delivery channels, tailoring methods, or engagement approaches that might outperform standard programs. Third, it highlights multi-level and multi-behavior approaches, meaning interventions can simultaneously address more than one behavior (for example, diet and physical activity together, or smoking and alcohol use) and can operate across levels of influence (individual, interpersonal, clinical, community, organizational, and policy environments). Fourth, it actively invites innovative research designs, methodologies, and technologies, which can include new analytic strategies, adaptive or efficient trial designs, pragmatic approaches, implementation-sensitive methods, and technology-enabled delivery or measurement tools.
In terms of what behaviors can be targeted, the FOA is broadly scoped around modifiable factors that have strong links to cancer prevention, treatment outcomes, and quality of life. Eligible target areas include diet, obesity, physical activity and sedentary behavior, smoking, sleep and circadian dysfunction, alcohol use, and adherence to cancer-related medical regimens. The adherence category can encompass behaviors like screening follow-through, surveillance, chemoprevention adherence when relevant, treatment adherence, and other medical regimen behaviors that influence cancer outcomes. The program is not limited to one point in the cancer trajectory; research can address any part of the cancer continuum, from prevention and risk reduction to survivorship and long-term management. It is also open across the translational spectrum, allowing projects that range from foundational behavioral intervention development to more applied, real-world testing, depending on the aims and stage of the science.
Eligibility is broad and includes a wide mix of organization types that can credibly conduct or support research. Eligible applicants include state, county, city, township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations (other than small businesses); small businesses; and additional entities as allowed under the NIH eligibility language. This wide eligibility signals an interest in leveraging diverse research settings and partnerships, including academic, healthcare, community, governmental, and private-sector environments, which is often essential for addressing behavioral risks and disparities at scale.
From the administrative details provided, this is a discretionary grant under the NIH (Agency: HHS-NIH11) with CFDA numbers 93.399. The award ceiling listed is $200,000, indicating the opportunity is aimed at smaller, exploratory projects rather than large, multi-site trials. The FOA was posted and created on May 23, 2016, with a closing date of May 7, 2019, reflecting that it was a time-bound opportunity in that cycle. Overall, the opportunity is best understood as NIH support for inventive, theory-informed, and methodologically modern behavioral intervention research that can meaningfully improve cancer-related behaviors and help reduce inequities across populations.
FAQs: Stimulating Innovations in Behavioral Intervention Research for Cancer Prevention and Control (R21) (PAR 16-278)
What is the name of this grant opportunity?
The opportunity is titled Stimulating Innovations in Behavioral Intervention Research for Cancer Prevention and Control (R21) with FOA number PAR 16-278.
Which agency is offering this funding opportunity?
This is a National Institutes of Health (NIH) funding opportunity within the U.S. Department of Health and Human Services (HHS). The administrative listing notes Agency: HHS-NIH11.
What is the main purpose or goal of this FOA?
The central goal is to support early-stage, high-impact behavioral intervention research that develops innovative interventions to improve cancer-related health behaviors, with an explicit focus on relevance and effectiveness across diverse racial and ethnic populations.
What grant mechanism does this FOA use?
This FOA uses the R21 exploratory/developmental grant mechanism, which is generally intended for projects that test bold ideas, pilot promising approaches, or generate preliminary evidence to support a larger follow-on study.
What kinds of projects are a good fit for an R21 under this program?
Based on the description provided, a good fit includes projects that are exploratory and innovative, such as piloting new intervention approaches, testing novel concepts, and producing early evidence that could justify later, larger-scale research.
What populations does the FOA emphasize?
The FOA explicitly emphasizes interventions that are relevant and effective across diverse racial and ethnic populations, reflecting a focus on real-world relevance and persistent disparities.
What are the main research thrusts highlighted in the FOA?
The FOA emphasizes four broad thrusts: (1) testing new theories and conceptual frameworks for changing cancer-related behaviors, (2) developing and evaluating novel strategies to improve behaviors linked to cancer risk, survivorship, and outcomes, (3) designing multi-level and multi-behavior interventions, and (4) using innovative research designs, methodologies, and technologies.
What does the FOA mean by testing new theories or conceptual frameworks?
It encourages investigators to explore theories and frameworks that can better explain and change cancer-related behaviors, particularly where existing models do not adequately address real-world complexity, culture, context, or persistent disparities.
What kinds of intervention innovations are encouraged?
The FOA encourages novel strategies such as creative intervention content, new delivery channels, improved tailoring methods, and stronger engagement approaches that may outperform standard programs.
What is meant by multi-behavior interventions?
Multi-behavior interventions address more than one behavior at the same time, such as diet and physical activity together or smoking and alcohol use together.
What is meant by multi-level interventions?
Multi-level interventions operate across multiple levels of influence, including individual, interpersonal, clinical, community, organizational, and policy environments.
What kinds of research designs, methods, or technologies are encouraged?
The FOA invites innovative designs and approaches including new analytic strategies, adaptive or efficient trial designs, pragmatic approaches, implementation-sensitive methods, and technology-enabled delivery or measurement tools.
Which behaviors can be targeted by projects under this FOA?
The FOA is broadly scoped to modifiable factors linked to cancer prevention, treatment outcomes, and quality of life. Eligible target areas include diet, obesity, physical activity and sedentary behavior, smoking, sleep and circadian dysfunction, alcohol use, and adherence to cancer-related medical regimens.
What does "adherence to cancer-related medical regimens" include?
As described, adherence can include behaviors such as screening follow-through, surveillance, chemoprevention adherence when relevant, treatment adherence, and other regimen-related behaviors that influence cancer outcomes.
At what point in the cancer journey can the research focus?
The FOA is not limited to one point in the cancer trajectory. Projects may address any part of the cancer continuum, including prevention and risk reduction, survivorship, and long-term management.
Does the FOA allow both early-stage and more applied research?
Yes. The description states it is open across the translational spectrum, allowing projects that range from foundational intervention development to more applied, real-world testing, depending on the aims and stage of the science.
Who is eligible to apply?
Eligibility is broad and includes many organization types, such as: state/county/city/township/special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations (other than small businesses); small businesses; and other entities allowed under NIH eligibility language.
Are for-profit organizations eligible?
Yes. The eligibility list includes for-profit organizations (other than small businesses) and also separately includes small businesses.
Are tribal governments or tribal organizations eligible?
Yes. The eligibility list includes federally recognized Native American tribal governments and other tribal organizations.
Are nonprofits required to have 501(c)(3) status?
No. The eligibility list includes nonprofits with or without 501(c)(3) status (other than institutions of higher education).
What is the CFDA number for this opportunity?
The CFDA number provided is 93.399.
What is the maximum award amount listed (award ceiling)?
The award ceiling listed is $200,000, indicating the opportunity is designed for smaller, exploratory projects rather than large, multi-site trials.
What type of grant is this described as?
It is described as a discretionary grant under NIH.
When was this FOA posted and created?
The FOA was posted and created on May 23, 2016.
What was the closing date listed for this opportunity?
The closing date listed is May 7, 2019, indicating it was time-bound within that cycle.
How should someone interpret this opportunity overall?
Overall, it is NIH support for inventive, theory-informed, and methodologically modern behavioral intervention research aimed at improving cancer-related behaviors and reducing inequities across populations, using an exploratory R21 structure and a smaller funding ceiling.
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