Opportunity Information: Apply for CDC RFA GH12 1212

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Strengthening Capacity through Improved Management and Coordination of Laboratory, Surveillance, Epidemiology Public Health Evaluations and Training in Uganda under PEPFAR" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067 Global AIDS.
  • This funding opportunity was created on Feb 19, 2012 and posted on Feb 19, 2012.
  • Applicants must submit their applications by Apr 17, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $17,500,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $3,500,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • The Uganda Virus Research Institute (UVRI) houses the HIV Reference and Quality Assurance Laboratory (HRL). The Ministry of Health (MOH) has designated the HRL at UVRI to be the National HIV Reference and Quality Assurance Laboratory in Uganda and to be the sole provider of HIV related, quality assurance (QA) for the country, no other laboratory in the country has the mandate to perform this activity. The Institute prepares and distributes proficiency testing (PT) panels to over one thousand laboratories and programs, in both the public and private sectors, that offer HIV testing has established and manages a national external quality assurance scheme (NEQAS) for CD4 T cell counting in collaboration with the Central Public Health Laboratory houses the National HIVDR Coordination Centre that conducts surveillance for HIVDR and includes a WHO certified laboratory for HIVDR determination that provides QA for other laboratories conducting HIVDR testing and, provides QA and HIVDR testing for the national HIV Early Infant Diagnosis program. As the unique provider of quality assurance for HIV related laboratory testing in the country, UVRI is in the perfect position to broaden its quality assurance activities into other HIV related HIV testing, to offer training through its relationship with Makerere University and to collect HIV surveillance data through the strengthening of its IT capacity.
Apply for CDC RFA GH12 1212

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Opportunity Summary:

This funding opportunity, titled "Strengthening Capacity through Improved Management and Coordination of Laboratory, Surveillance, Epidemiology Public Health Evaluations and Training in Uganda under PEPFAR" (CDC RFA GH12-1212), is a CDC cooperative agreement designed to build stronger national systems in Uganda so the Ministry of Health can deliver health services that are faster, more reliable, and higher quality. The core idea is not just to fund isolated activities, but to improve the way key public health functions are managed and coordinated across laboratory services, disease surveillance, epidemiology, program evaluation, operational research, training, and financial operations. Because it is structured as a cooperative agreement, the CDC would typically have substantial programmatic involvement, meaning the recipient and CDC would work closely together to shape implementation, monitor progress, and ensure the work supports national and PEPFAR goals.

The opportunity sits under CFDA 93.067 (Global AIDS) and is explicitly tied to PEPFAR, which signals an emphasis on HIV-related systems and outcomes, even when strengthening broader public health capacity. The announcement anticipated a single award, indicating the work was intended to be centralized under one primary implementing institution rather than split among multiple organizations. Funding levels were significant: an estimated total of $17.5 million, with an annual award range (as stated in the listing) from $800,000 to $3.5 million. There was no cost-sharing or matching requirement, which generally lowers barriers to participation and allows the project to focus resources directly on program activities rather than required recipient contributions.

A major feature of this FOA is the clear alignment with Uganda's existing national laboratory leadership and quality assurance infrastructure, particularly at the Uganda Virus Research Institute (UVRI). The eligibility information strongly suggests that UVRI was the pivotal institution expected to carry out the work, because it houses the HIV Reference and Quality Assurance Laboratory (HRL) that the Ministry of Health has designated as the National HIV Reference and Quality Assurance Laboratory for Uganda. The announcement emphasizes that no other laboratory in the country holds the mandate to perform HIV-related quality assurance at the national level, making UVRI uniquely positioned to lead a coordinated national effort. In practical terms, that means the project would likely use UVRI's national mandate and technical assets to improve the performance and consistency of HIV testing and related laboratory services across both public and private sectors.

The description highlights several specific national functions UVRI already performs that this award would support and expand. UVRI prepares and distributes proficiency testing panels to more than a thousand laboratories and programs offering HIV testing, which is a key mechanism for verifying testing accuracy and maintaining standards across a wide network. UVRI also established and manages a national external quality assurance scheme for CD4 T-cell counting in collaboration with the Central Public Health Laboratory, reinforcing the broader laboratory system that supports HIV care and treatment monitoring. In addition, UVRI houses the National HIV Drug Resistance (HIVDR) Coordination Centre and includes a WHO-certified laboratory for HIV drug resistance determination. That laboratory provides quality assurance for other HIVDR testing sites, conducts surveillance for HIV drug resistance, supports quality assurance for HIVDR testing, and provides HIVDR testing and QA for Uganda's Early Infant Diagnosis program. Taken together, these details show that the FOA is grounded in strengthening national reference functions that have downstream impact on clinical care, surveillance, and program decision-making.

Beyond laboratory quality, the opportunity emphasizes improved management and coordination of surveillance, epidemiology, and public health evaluation, alongside financial activities and operational research. This signals an intent to improve how data is generated, validated, analyzed, and used for action, while also strengthening the administrative and financial systems that keep large-scale public health programs functioning. The mention of strengthening information technology capacity is important here: the FOA points to the need to better collect and manage HIV surveillance data, and it frames UVRI as being in a strong position to do that through enhanced IT systems. In real-world terms, this kind of investment typically supports better data flow from peripheral sites to national systems, improved data quality checks, more timely reporting, and stronger analytic capacity for surveillance and program monitoring.

Training is another explicit pillar of the opportunity. UVRI is described as being able to offer training through its relationship with Makerere University, which implies that this award was meant to strengthen not only systems but also the workforce that runs them. That can include training laboratorians in quality management systems, proficiency testing participation and corrective actions, biosafety, and new diagnostic methods, as well as training epidemiologists and surveillance staff in data management, analysis, and outbreak or program evaluation methods. Because the FOA also references operational research, the intent likely includes helping teams design and conduct practical studies that answer implementation questions, identify bottlenecks, and test improvements that can be scaled within the national program.

Administratively, the opportunity was posted February 19, 2012, and closed April 17, 2012, with an archive date of May 17, 2012. It was categorized as discretionary funding in the health activity area. The listed CDC contact for assistance accessing the full announcement was the CDC Procurement and Grants Office (PGO) TIMS help line (770-488-2700) and email (pgotim@cdc.gov). Overall, the FOA can be read as a systems-strengthening investment meant to consolidate and expand Uganda's national capacity for HIV laboratory quality assurance, drug resistance surveillance, and evidence-driven program management, while also improving the coordination, evaluation, financial management, and training structures that allow the Ministry of Health to deliver timely and dependable services under PEPFAR.

Frequently Asked Questions (FAQs)

1. What is the title and reference number of this funding opportunity?

The opportunity is titled "Strengthening Capacity through Improved Management and Coordination of Laboratory, Surveillance, Epidemiology Public Health Evaluations and Training in Uganda under PEPFAR" and is identified as CDC RFA GH12-1212.

2. What type of award is this?

This is a CDC cooperative agreement. In a cooperative agreement, CDC typically has substantial programmatic involvement, meaning CDC and the recipient work closely together on implementation, monitoring, and alignment with national and PEPFAR goals.

3. What is the overall purpose of the award?

The purpose is to strengthen national systems in Uganda so the Ministry of Health can deliver services that are faster, more reliable, and higher quality. The focus is on improving management and coordination across key public health functions rather than funding isolated stand-alone activities.

4. Which technical areas does the opportunity aim to strengthen?

The opportunity emphasizes improved management and coordination across laboratory services, disease surveillance, epidemiology, public health evaluation, operational research, training, information technology capacity related to surveillance data, and financial operations.

5. How is this opportunity connected to PEPFAR and HIV?

The opportunity is explicitly tied to PEPFAR and is listed under CFDA 93.067 (Global AIDS). This signals a strong emphasis on HIV-related systems and outcomes, including HIV testing quality assurance and HIV drug resistance surveillance, even while strengthening broader public health capacity.

6. How many awards were anticipated?

The announcement anticipated a single award, suggesting the work was intended to be centralized under one primary implementing institution rather than divided among multiple organizations.

7. What funding levels were described in the listing?

The listing described an estimated total funding amount of $17.5 million, and an annual award range of $800,000 to $3.5 million.

8. Is cost sharing or matching required?

No. The opportunity stated there was no cost-sharing or matching requirement.

9. Which institution is strongly indicated as the expected lead implementer?

The eligibility discussion strongly suggests the Uganda Virus Research Institute (UVRI) as the pivotal institution expected to carry out the work, based on its national mandate and existing infrastructure for HIV reference and quality assurance functions.

10. Why is UVRI positioned as uniquely suited for this work?

UVRI houses the HIV Reference and Quality Assurance Laboratory (HRL) that the Ministry of Health has designated as the National HIV Reference and Quality Assurance Laboratory for Uganda. The announcement emphasizes that no other laboratory in the country holds the mandate to perform HIV-related quality assurance at the national level.

11. What national laboratory quality assurance functions are highlighted?

The announcement highlights that UVRI prepares and distributes proficiency testing panels to more than a thousand laboratories and programs offering HIV testing. This supports nationwide verification of testing accuracy and consistent performance across a large network.

12. Does the opportunity include support for CD4 testing quality assurance?

Yes. UVRI is described as having established and managed a national external quality assurance scheme for CD4 T-cell counting in collaboration with the Central Public Health Laboratory, and the award would support and expand these kinds of national quality functions.

13. What HIV drug resistance (HIVDR) capabilities are included in the scope?

UVRI houses the National HIV Drug Resistance (HIVDR) Coordination Centre and includes a WHO-certified laboratory for HIV drug resistance determination. The described functions include quality assurance for other HIVDR testing sites, HIVDR surveillance, support for HIVDR testing quality assurance, and HIVDR testing and QA for Uganda's Early Infant Diagnosis program.

14. How does the opportunity address surveillance, epidemiology, and evaluation?

It emphasizes improved management and coordination of surveillance, epidemiology, and public health evaluations, indicating a focus on strengthening how data is generated, validated, analyzed, and used for decision-making and public health action.

15. What role does information technology (IT) capacity play in this opportunity?

The opportunity mentions strengthening IT capacity to better collect and manage HIV surveillance data. This is framed as supporting improved data flow, data quality, timelier reporting, and stronger analytics for surveillance and program monitoring.

16. What kinds of training are contemplated?

Training is an explicit pillar. The announcement notes UVRI's ability to offer training through its relationship with Makerere University. Training could support the workforce involved in laboratory quality systems, proficiency testing practices, biosafety, diagnostic methods, and surveillance/epidemiology skills such as data management and analysis.

17. Is operational research part of the planned work?

Yes. The opportunity references operational research as part of the broader intent to strengthen program performance and evidence-driven decision-making.

18. What administrative and financial strengthening is included?

The description includes improved management and coordination of financial activities alongside technical functions. This indicates an intent to strengthen the administrative and financial systems that support large-scale public health programming.

19. When was the opportunity posted and when did it close?

The opportunity was posted on February 19, 2012, and closed on April 17, 2012. An archive date of May 17, 2012 was also provided.

20. What funding category and activity area were listed?

It was categorized as discretionary funding in the health activity area.

21. What is the CFDA number associated with this opportunity?

The opportunity sits under CFDA 93.067 (Global AIDS).

22. Who was listed as the contact for help accessing the full announcement?

The listed contact was the CDC Procurement and Grants Office (PGO) TIMS help line at 770-488-2700 and the email address pgotim@cdc.gov.

23. What is the main difference between this opportunity and a project focused on isolated activities?

The core idea is systems strengthening: improving the management and coordination of connected national functions (labs, surveillance, epidemiology, evaluation, training, IT, and financial operations) so improvements are consistent and scalable rather than limited to single sites or one-off activities.

24. How would this work impact HIV testing services across Uganda?

By strengthening national reference and quality assurance functions (including proficiency testing distributed to a large network of HIV testing sites), the opportunity is intended to improve the performance and consistency of HIV testing and related laboratory services across both public and private sectors.

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