Strengthening Strategic Information, program implementation and Capacity Building in order to reduce morbidity and mortality in the Republic of South Africa under the President’s Emergency Plan for AIDS Relief (PEPFAR) | Apply Online

Opportunity Summary:

This funding opportunity is a continuation cooperative agreement from the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), under PEPFAR, focused on South Africa. The program is titled "Strengthening Strategic Information, program implementation and Capacity Building in order to reduce morbidity and mortality in the Republic of South Africa under the President's Emergency Plan for AIDS Relief (PEPFAR)" and it centers on improving how HIV-related programs are planned, measured, and carried out so that HIV-associated illness and deaths are reduced at scale.

A key emphasis is "Strategic Information," which in PEPFAR and CDC terms typically refers to the systems and capabilities used to generate, analyze, interpret, and use data for decision-making. In practice, this often includes strengthening monitoring and evaluation, improving data quality, supporting surveillance and reporting systems, and ensuring that program data can be translated into actionable insights for targeting services, tracking outcomes, and demonstrating impact. The goal is not data for its own sake, but better data that leads to better program choices, faster course correction, and more effective delivery of HIV prevention, care, and treatment services.

Alongside data and information systems, the opportunity highlights program implementation support. That generally means helping implementing partners and public-sector counterparts run HIV programs more effectively by improving planning, coordination, operational processes, and performance management. It can involve strengthening routine program oversight, supporting the roll-out of evidence-based interventions, aligning activities with national guidelines and PEPFAR priorities, and ensuring that services are delivered with quality and consistency. The ultimate purpose of this implementation support is to improve health outcomes, specifically lowering morbidity and mortality related to HIV in South Africa.

Capacity building is the third major pillar. Capacity building commonly includes developing the skills, tools, and institutional systems needed for sustainability, so that South African institutions and programs can maintain and improve HIV services over time. This may include training and mentorship, strengthening management and leadership functions, improving the ability to conduct evaluations and use findings, and supporting systems that make programs resilient, accountable, and capable of continuous improvement. The framing suggests an intent to reinforce both technical capacity (for strategic information and program operations) and organizational capacity (governance, staffing, systems, and processes).

Administratively, the opportunity is listed as a continuation award, meaning it is intended to continue or extend ongoing work rather than launch an entirely new, open competition. The funding instrument is a cooperative agreement, which typically indicates that CDC expects substantial involvement in the project, such as collaboration on technical direction, performance monitoring, and alignment with PEPFAR strategies and reporting requirements. The opportunity falls under the Health funding activity category, with CFDA number 93.067, which aligns with CDC global health and PEPFAR-related activities.

The eligibility category is listed as "Others (see text field entitled Additional Information on Eligibility for clarification)," which signals that eligibility was likely limited or defined by specific criteria in the full announcement, often consistent with continuation funding where only current recipients or a defined set of partners can apply. The posting shows an estimated 10 awards, indicating multiple ongoing projects or partners may have been supported under this continuation cycle. The award ceiling is listed as 0, which usually reflects that the ceiling was not specified in the summary record and would instead be detailed in the full funding announcement or determined by continuation budgets and available funds.

The opportunity was created on September 22, 2016, with an original closing date of November 22, 2016. The administering agency is the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), specifically the Center for Global Health (CGH). Overall, the grant is designed to reinforce the information and operational backbone of HIV programs in South Africa under PEPFAR, so that decisions are driven by stronger data, implementation is more effective, and local capacity grows in ways that translate into fewer illnesses and deaths.

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Previous opportunity: Engaging Local Non-Governmental Organizations (NGOs) in the Provision of High Quality HIV Care and Treatment to Vulnerable Populations in Southwestern and Western China under the President’s Emergency Plan for AIDS Relief (PEPFAR)

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