Opportunity Information: Apply for PA 11 055
Apply for PA 11 055
- The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Studies in Neonatal Hypoglycemia (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Dec 2, 2010 and posted on Dec 2, 2010.
- Applicants must submit their applications by May 7, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Private institutions of higher education State governments Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses City or township governments County governments Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments Small businesses Public housing authorities/Indian housing authorities.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Studies in Neonatal Hypoglycemia (R21) opportunity (Funding Opportunity Number PA-11-055) is a National Institutes of Health grant announcement administered by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). It is aimed at supporting exploratory and developmental research projects that address neonatal hypoglycemia, with an emphasis on basic, applied, and translational studies. The central motivation behind the program is that, although research has improved the field's understanding of why newborns develop abnormal glucose regulation and what biological mechanisms are involved, there are still important unanswered questions about neonatal glucose homeostasis. NICHD is using this program to help close those gaps in knowledge in ways that could eventually improve how clinicians monitor at-risk newborns and how neonatal hypoglycemia is treated or prevented.
This announcement uses the NIH Exploratory/Developmental Research Grant mechanism (R21), which is typically designed for early-stage, high-impact, or proof-of-concept work that can generate key preliminary data or test innovative approaches. The FOA is described as running in parallel with other NIH announcements that share the same scientific scope but use different grant mechanisms, specifically PA-11-053 (R01) and PA-11-054 (R03). In practical terms, that means applicants whose ideas fit neonatal hypoglycemia research have multiple NIH pathways depending on the maturity, scale, and budget needs of the proposed work: R21 for exploratory projects, R03 for small-scale projects, and R01 for more extensive research programs.
Funding levels under this R21 announcement are variable because project needs can differ widely across neonatal hypoglycemia studies (for example, mechanistic lab work versus translational clinical studies). The listed award ceiling is $200,000. The program does not specify a fixed number of awards; instead, the total number of funded projects and the total dollars awarded are expected to depend on the number of applications received, their scientific quality, their proposed duration, and their requested budgets. There is no cost sharing or matching requirement, which means applicants are not required to provide non-federal funds as a condition of receiving an award.
Eligibility is broad and is structured to allow participation from many types of organizations that can contribute to this research area. Eligible applicants include public and private institutions of higher education, nonprofit organizations (including both 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (other than small businesses), small businesses, and a wide range of government entities (state, county, city or township, special district governments, and certain public housing authorities/Indian housing authorities). Tribal entities are explicitly included, including federally recognized tribal governments and other tribal organizations, as well as tribally controlled colleges and universities. The eligibility language also extends to a number of institution types and communities often emphasized in federal research programs, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and faith-based or community-based organizations. Importantly, the announcement also indicates that non-U.S. entities (foreign organizations) and regional organizations may be eligible, along with U.S. territories or possessions and eligible federal agencies, which signals an interest in drawing on the best expertise available, even when it sits outside the typical U.S. academic environment.
From an administrative standpoint, the opportunity is categorized as a discretionary grant in the health domain (Funding Activity Category: Health; CFDA number 93.865, Child Health and Human Development Extramural Research). The announcement was posted and created on December 2, 2010, with an original and current closing date listed as May 7, 2014, and an archive date of June 7, 2014. While that means this specific FOA is no longer open, the summary still reflects how NICHD framed its research priorities at the time: encouraging innovative R21 proposals that can advance understanding of neonatal hypoglycemia and translate that understanding into better clinical monitoring and treatment strategies for newborns with altered glucose homeostasis. The full text of the announcement was hosted through the NIH Grants Guide (link provided in the source), and technical access issues were directed to the NIH Office of Extramural Research (OER) webmaster contacts included in the notice.
Frequently Asked Questions (FAQs): Studies in Neonatal Hypoglycemia (R21) - PA-11-055
What is the Studies in Neonatal Hypoglycemia (R21) funding opportunity?
Studies in Neonatal Hypoglycemia (R21) is an NIH grant funding opportunity (Funding Opportunity Number PA-11-055) administered by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). It supports exploratory and developmental research projects focused on neonatal hypoglycemia, including basic, applied, and translational studies.
Which NIH institute administers this opportunity?
This opportunity is administered by NICHD (the Eunice Kennedy Shriver National Institute of Child Health and Human Development), a component of the National Institutes of Health (NIH).
What research topic area does this FOA focus on?
The FOA focuses on neonatal hypoglycemia and broader questions around neonatal glucose homeostasis. It is intended to support research that improves understanding of abnormal glucose regulation in newborns and the biological mechanisms involved.
What is the main motivation for this program?
The central motivation is that, even though research has improved understanding of why newborns develop abnormal glucose regulation and the biological mechanisms involved, important unanswered questions remain about neonatal glucose homeostasis. NICHD used this program to encourage studies that close those gaps in ways that could ultimately improve clinical monitoring and the treatment or prevention of neonatal hypoglycemia.
What types of studies are encouraged under this announcement?
The announcement emphasizes basic, applied, and translational studies. It is framed to support innovative and exploratory work that can advance mechanistic understanding and help move findings toward clinical monitoring and treatment strategies for at-risk newborns.
What grant mechanism does this FOA use?
This FOA uses the NIH Exploratory/Developmental Research Grant mechanism (R21). R21s are typically used for early-stage, high-impact, or proof-of-concept research that can generate key preliminary data or test innovative approaches.
How does the R21 mechanism fit compared to related NIH mechanisms mentioned?
The FOA is described as running in parallel with other NIH announcements that share the same scientific scope but use different mechanisms: PA-11-053 (R01) and PA-11-054 (R03). In practical terms, R21 is positioned for exploratory projects, R03 for small-scale projects, and R01 for more extensive research programs.
What is the maximum award amount mentioned for this R21 opportunity?
The listed award ceiling is $200,000.
Are funding levels fixed or variable under this announcement?
Funding levels are described as variable because project needs can differ widely across neonatal hypoglycemia studies (for example, mechanistic laboratory studies versus translational clinical studies).
Is there a set number of awards expected?
No. The program does not specify a fixed number of awards. The total number of funded projects and total dollars awarded are expected to depend on the number of applications received, scientific quality, proposed duration, and requested budgets.
Is cost sharing or matching required?
No. There is no cost sharing or matching requirement, meaning applicants are not required to provide non-federal funds as a condition of receiving an award.
Who is eligible to apply?
Eligibility is broad. Eligible applicants include public and private institutions of higher education; nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) entities); for-profit organizations (other than small businesses); small businesses; and a wide range of government entities, including state, county, city or township, special district governments, and certain public housing authorities/Indian housing authorities.
Are tribal entities eligible?
Yes. Tribal entities are explicitly included, including federally recognized tribal governments and other tribal organizations, as well as tribally controlled colleges and universities.
Are institutions like HBCUs and Hispanic-serving institutions included in eligibility?
Yes. The eligibility language extends to institution types and communities often emphasized in federal research programs, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and faith-based or community-based organizations.
Can non-U.S. (foreign) organizations apply?
Yes. The announcement indicates that non-U.S. entities (foreign organizations) and regional organizations may be eligible. It also notes eligibility for U.S. territories or possessions and eligible federal agencies.
What is the funding activity category and CFDA number listed?
The opportunity is categorized under the Funding Activity Category: Health, and it lists CFDA number 93.865 (Child Health and Human Development Extramural Research).
Is this FOA still open for applications?
No. The announcement lists an original and current closing date of May 7, 2014, and an archive date of June 7, 2014, which indicates this specific FOA is no longer open.
When was the FOA posted?
The announcement was posted and created on December 2, 2010.
Where was the full text of the announcement hosted?
The full text of the announcement was hosted through the NIH Grants Guide (as referenced in the source summary).
Who is listed for technical access issues related to the announcement?
Technical access issues were directed to the NIH Office of Extramural Research (OER) webmaster contacts included in the notice.
What clinical impact is NICHD aiming for through this research program?
NICHD framed this program around the idea that improved knowledge of neonatal glucose homeostasis could eventually improve how clinicians monitor at-risk newborns and how neonatal hypoglycemia is treated or prevented.
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