Opportunity Information: Apply for PAR 11 224
Apply for PAR 11 224
- The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Studies in Neonatal Resuscitation (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Jun 8, 2011 and posted on Jun 8, 2011.
- Applicants must submit their applications by Sep 19, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $275,000.00 in funding.
- Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments City or township governments County governments For profit organizations other than small businesses Small businesses Public and State controlled institutions of higher education Private institutions of higher education Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Foreign (non U.S.) components of U.S. Organizations are allowed.
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Opportunity Summary:
The Studies in Neonatal Resuscitation (R21) funding opportunity (PAR-11-224) is a National Institutes of Health (NIH) discretionary grant program designed to spur exploratory, early-stage research that can improve how newborns are stabilized and supported at birth. Its core aim is to generate new knowledge and practical evidence related to neonatal resuscitation, with the expectation that strong findings will translate into evidence-based practices that promote a safer, smoother transition from fetal to newborn life and ultimately improve both short-term and long-term outcomes for infants.
The scientific scope is intentionally broad, inviting projects that address multiple dimensions of resuscitation science and care. Examples of encouraged topic areas include fetal-neonatal transitional physiology, especially cardiovascular and pulmonary changes around the time of delivery; refining and optimizing the steps and sequence of resuscitation interventions; understanding how management of the third stage of labor may affect the fetus and immediate neonatal condition; resuscitation approaches for infants with congenital malformations; and evaluating how resuscitation strategies and exposures influence longer-term developmental and health outcomes. The announcement emphasizes that these examples are not exhaustive, and applicants can propose other compelling neonatal resuscitation questions that fit the overall purpose of strengthening the evidence base.
A major feature of the opportunity is its openness to diverse study designs and methodologies. Applicants may propose epidemiological research, studies using fetal or neonatal animal models, computer-based or information-technology driven simulations, clinical observational studies, analyses of existing national or regional datasets, and prospective randomized controlled trials. Mixed-method or combined approaches are also acceptable, allowing investigators to integrate multiple data sources or experimental strategies to answer clinically meaningful questions. The overall intent is to encourage well-conducted studies that can move the field toward practical guidance for clinicians and health systems, including clearer best practices during critical minutes after birth.
This is an R21 mechanism, which generally supports exploratory or developmental projects that can establish feasibility, generate preliminary data, or open up promising new directions that may later be scaled into larger studies. The award ceiling listed for this opportunity is $275,000, and there is no cost-sharing or matching requirement. The program is categorized under CFDA 93.865 (Child Health and Human Development Extramural Research), reflecting its alignment with maternal and child health priorities.
Eligibility is broad and includes many types of organizations. Eligible applicants encompass nonprofit organizations (including 501(c)(3) and non-501(c)(3) nonprofits), public housing authorities/Indian housing authorities, tribal governments and tribal organizations (including some non-federally recognized entities as specified), special district governments, state and local governments (city/township and county), independent school districts, for-profit organizations (including small businesses and other for-profits), and higher education institutions (public/state-controlled and private). The announcement also notes additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Hispanic-Serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, U.S. territories or possessions, regional organizations, and non-U.S. entities (foreign organizations). Foreign components of U.S. organizations are allowed as well, expanding the opportunity for international collaboration or multi-site research when scientifically justified.
Key administrative details include a posted date of June 8, 2011, with an original and current closing date of September 19, 2013, and an archive date of October 20, 2013. The listing identifies NIH as the sponsoring agency, and provides a link to the full announcement at http://grants.nih.gov/grants/guide/pa-files/PAR-11-224.html. For technical issues accessing or linking to the announcement, the contact is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
Overall, this opportunity was structured to attract innovative, clinically relevant neonatal resuscitation research across basic physiology, applied clinical practice, data science, and outcomes research. The program emphasizes translation: producing results that can be converted into practical, evidence-based resuscitation guidance so more newborns can begin life with the best possible chance for healthy development.
Frequently Asked Questions (FAQs): Studies in Neonatal Resuscitation (R21) - PAR-11-224
What is the Studies in Neonatal Resuscitation (R21) opportunity (PAR-11-224)?
PAR-11-224 is a National Institutes of Health (NIH) discretionary grant opportunity using the R21 mechanism to support exploratory, early-stage research focused on neonatal resuscitation. The goal is to generate new knowledge and practical evidence that improves how newborns are stabilized and supported at birth.
What is the main purpose of this funding opportunity?
The core purpose is to strengthen the evidence base for neonatal resuscitation so that results can translate into evidence-based practices. The intended impact is a safer, smoother transition from fetal to newborn life and improved short-term and long-term outcomes for infants.
What kinds of research topics are encouraged?
The scientific scope is broad. Examples of encouraged topics include:
- Fetal-neonatal transitional physiology, including cardiovascular and pulmonary changes around delivery
- Refining and optimizing the steps and sequence of resuscitation interventions
- How management of the third stage of labor may affect the fetus and immediate neonatal condition
- Resuscitation approaches for infants with congenital malformations
- How resuscitation strategies and exposures influence longer-term developmental and health outcomes
Are applicants limited to the example topics listed in the announcement?
No. The examples are explicitly described as not exhaustive. Other neonatal resuscitation questions may be proposed if they fit the overall purpose of strengthening the evidence base and improving practice.
What study designs and methods are allowed?
The opportunity is open to diverse methodologies, including epidemiological research, fetal or neonatal animal models, computer-based or information-technology-driven simulations, clinical observational studies, analyses of existing national or regional datasets, and prospective randomized controlled trials. Mixed-method or combined approaches are also acceptable.
Can an application combine multiple approaches (for example, datasets plus clinical observation)?
Yes. The announcement indicates that mixed-method or combined approaches are acceptable, including integrating multiple data sources or experimental strategies to address clinically meaningful questions.
Does the program emphasize translation to clinical practice?
Yes. A central emphasis is translation: producing results that can be converted into practical, evidence-based resuscitation guidance for clinicians and health systems, particularly during the critical minutes after birth.
What is the NIH R21 mechanism intended to support?
The R21 mechanism generally supports exploratory or developmental projects intended to establish feasibility, generate preliminary data, or open new research directions that could later be scaled into larger studies.
What is the funding ceiling for this opportunity?
The award ceiling listed for this opportunity is $275,000.
Is cost-sharing or matching required?
No. The opportunity states there is no cost-sharing or matching requirement.
What CFDA number is associated with this program?
This opportunity is categorized under CFDA 93.865 (Child Health and Human Development Extramural Research).
Who is eligible to apply?
Eligibility is broad and includes many organization types, such as nonprofit organizations (501(c)(3) and non-501(c)(3)), public housing authorities/Indian housing authorities, tribal governments and tribal organizations (including certain non-federally recognized entities as specified), special district governments, state and local governments, independent school districts, for-profit organizations (including small businesses), and institutions of higher education (public/state-controlled and private).
Are specific institution types (HBCUs, HSIs, etc.) mentioned as eligible?
Yes. The announcement notes additional eligible categories including Alaska Native and Native Hawaiian Serving Institutions, Hispanic-Serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and faith-based or community-based organizations.
Are U.S. federal agencies eligible?
Yes. The opportunity lists eligible federal agencies among the eligible applicant categories.
Are U.S. territories or possessions eligible?
Yes. The announcement includes U.S. territories or possessions as eligible.
Are regional organizations eligible?
Yes. Regional organizations are included among the eligible applicant categories.
Can foreign organizations apply?
Yes. Non-U.S. entities (foreign organizations) are identified as eligible, and foreign components of U.S. organizations are also allowed.
What is the sponsor agency for this opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
When was this opportunity posted?
The posted date listed is June 8, 2011.
What were the closing date and archive date?
The original and current closing date is September 19, 2013, and the archive date is October 20, 2013.
Where can applicants find the full announcement?
The full announcement is available at: http://grants.nih.gov/grants/guide/pa-files/PAR-11-224.html
Who should be contacted for technical issues accessing or linking to the announcement?
For technical issues, the contact listed is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
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Applicants also applied for:
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