Opportunity Information: Apply for RFA MH 09 150

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Suicide Prevention in Emergency Medicine Departments (U01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants.
  • This funding opportunity was created on Feb 9, 2009 and posted on Feb 9, 2009.
  • Applicants must submit their applications by Apr 14, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $3,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $2,000,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Native American tribal governments (Federally recognized) State governments Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public and State controlled institutions of higher education Special district governments For profit organizations other than small businesses.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
Apply for RFA MH 09 150

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Opportunity Summary:

The National Institute of Mental Health (NIMH), part of the National Institutes of Health (NIH), released this funding opportunity to address a major gap in how emergency departments handle patients at risk for suicide. Emergency medicine clinicians are often the first point of contact for people experiencing suicidal thoughts or behaviors, and they are expected to identify risk, triage appropriately, assess suicide risk, and arrange referrals for follow-up care. Despite how common and high stakes these situations are, the announcement emphasizes that there are no well-established, evidence-based standards guiding these ED practices. The need is becoming more urgent as more people are seeking emergency care specifically for suicidality, and the system is failing at a key handoff point: when ED staff refer patients to outpatient services, an estimated 50 to 70 percent of those at risk do not show up for their follow-up appointments. This dropout after discharge is highlighted as a central problem the grant aims to reduce.

The grant solicits cooperative research project applications (U01 mechanism) focused on developing and testing practical interventions that can build a real evidence base for better ED care for suicidal individuals. The intent is not just to propose ideas, but to rigorously evaluate whether these interventions work in real-world emergency department settings. The FOA frames improvement broadly as a "chain of care" that can include better patient screening, more effective assessment approaches, and ED-based interventions that connect patients to appropriate ongoing care in ways that actually stick. The interventions are expected to translate into measurable reductions in suicide risk and related harm, with outcomes tracked for at least 12 months after the ED visit, signaling an emphasis on sustained impact rather than short-term changes limited to the ED encounter itself.

A key theme in the announcement is generalizability. Applicants are encouraged to design approaches that can be tested across multiple general medical emergency departments rather than being tailored to a single specialized site. This focus reflects the practical reality that EDs vary widely in staffing, patient populations, resources, and local mental health service availability, so interventions that only work in one environment would have limited public health value. The ultimate objective is to generate evidence that can support improved standard practices in emergency departments and improve care after ED discharge, thereby reducing suicidal behavior and associated morbidity over the following year.

In terms of structure, this is a discretionary funding opportunity using a Cooperative Agreement (U01). The cooperative aspect typically means NIH/NIMH expects substantial scientific involvement during the project, such as collaboration on protocol development, coordination, milestones, or oversight, rather than operating as a more hands-off traditional research grant. For this specific FOA, NIMH planned to fund one award, with total FY 2009 committed funding of about $3,000,000 in total costs. The listed award ceiling is $2,000,000, indicating an upper bound on the size of an individual award under the announcement.

Eligibility is broad and includes many types of organizations that could realistically run multi-site emergency medicine research. Eligible applicants include state governments, tribal governments (federally recognized and other than federally recognized in the additional eligibility notes), special district governments, U.S. territories or possessions, public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including 501(c)(3) and non-501(c)(3) organizations), small businesses, and other for-profit organizations that are not small businesses. The announcement also explicitly includes institutions that serve specific populations, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and Indian/Native American Tribal Governments and organizations. There is no cost sharing or matching requirement, which lowers a common barrier for applicants and can make it easier for hospitals and academic partners to participate.

Key administrative details identify the opportunity as RFA MH 09 150 under CFDA 93.242 (Mental Health Research Grants). It was posted on February 9, 2009, with an application due date of April 14, 2009, and an archive date of May 15, 2009. The sponsoring agency is NIH, with NIMH as the institute issuing the FOA. The core takeaway is that this solicitation was designed to produce tested, scalable, ED-focused suicide prevention practices that improve identification, assessment, intervention, and follow-up linkage, with the explicit goal of reducing suicidal behavior and related harm over at least a year after the emergency visit.

Frequently Asked Questions (FAQs)

What agency is offering this grant opportunity?

This funding opportunity was released by the National Institute of Mental Health (NIMH), which is part of the National Institutes of Health (NIH).

What is the main problem this funding opportunity is trying to solve?

The opportunity targets a major gap in how general medical emergency departments (EDs) identify, assess, triage, intervene with, and refer patients who are at risk for suicide. The announcement highlights that ED clinicians are often the first point of contact for people experiencing suicidal thoughts or behaviors, yet there are no well-established, evidence-based standards guiding many ED suicide-related practices.

Why is emergency department (ED) suicide care a priority in this announcement?

The announcement emphasizes that more people are seeking emergency care specifically for suicidality, and ED encounters are high-stakes. It also underscores a key system failure after discharge: when ED staff refer patients to outpatient care, an estimated 50% to 70% of at-risk patients do not attend their follow-up appointments.

What type of application does the FOA request?

The FOA solicits cooperative research project applications using the U01 mechanism (a Cooperative Agreement).

What does the U01 Cooperative Agreement structure imply for applicants?

Because this is a Cooperative Agreement, NIH/NIMH expects substantial scientific involvement during the project. The announcement describes this as involvement such as collaboration on protocol development, coordination, milestones, or oversight, rather than a more hands-off approach typical of some traditional research grants.

What kinds of projects are expected to be proposed?

Projects are expected to develop and test practical interventions that build a real evidence base for improving ED care for suicidal individuals. The intent is not only to propose ideas, but to rigorously evaluate whether interventions work in real-world emergency department settings.

What does the FOA mean by improving the "chain of care"?

The FOA frames improvement as a chain of care that can include better patient screening, more effective assessment approaches, and ED-based interventions that connect patients to appropriate ongoing care in ways that improve follow-through after discharge.

Is the grant focused only on what happens during the ED visit?

No. The FOA emphasizes sustained impact beyond the ED encounter. Outcomes are expected to be tracked for at least 12 months after the ED visit, signaling an emphasis on longer-term reductions in suicide risk and related harm.

What outcomes is the FOA aiming to improve?

The FOA expects interventions to translate into measurable reductions in suicide risk and related harm, with follow-up outcomes tracked for at least 12 months after the ED visit.

What is the central follow-up problem the FOA highlights?

A central problem highlighted is dropout after ED discharge. The FOA states that an estimated 50% to 70% of patients at risk do not show up for their outpatient follow-up appointments after being referred from the ED.

Does the FOA encourage single-site or multi-site approaches?

The FOA emphasizes generalizability and encourages applicants to design approaches that can be tested across multiple general medical emergency departments, rather than being tailored to a single specialized site.

Why is generalizability emphasized?

The announcement notes that EDs vary widely in staffing, patient populations, resources, and local mental health service availability. Interventions that only work in one environment would have limited public health value, so the goal is evidence that can support improved standard practices across diverse ED settings.

How many awards did NIMH plan to make under this opportunity?

NIMH planned to fund one award under this FOA.

How much funding was committed for this opportunity?

The FOA states that total FY 2009 committed funding was about $3,000,000 in total costs.

What is the maximum (ceiling) award amount listed?

The listed award ceiling is $2,000,000, indicating an upper bound on the size of an individual award under the announcement.

Is cost sharing or matching required?

No. The FOA states there is no cost sharing or matching requirement.

Who is eligible to apply?

Eligibility is broad and includes state governments; tribal governments (federally recognized and other than federally recognized, as noted); special district governments; U.S. territories or possessions; public and state-controlled institutions of higher education; private institutions of higher education; nonprofits (including 501(c)(3) and non-501(c)(3)); small businesses; and other for-profit organizations that are not small businesses.

Are institutions serving specific populations explicitly included as eligible applicants?

Yes. The FOA explicitly includes institutions such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and Indian/Native American Tribal Governments and organizations.

What is the FOA number and CFDA program listing?

The opportunity is identified as RFA MH 09 150 under CFDA 93.242 (Mental Health Research Grants).

When was the opportunity posted and when were applications due?

The FOA was posted on February 9, 2009. The application due date was April 14, 2009.

What is the archive date listed for this opportunity?

The archive date is May 15, 2009.

What is the overarching objective of this funding opportunity?

The FOA was designed to produce tested, scalable, ED-focused suicide prevention practices that improve identification, assessment, intervention, and follow-up linkage, with the explicit goal of reducing suicidal behavior and associated morbidity over at least a year after the emergency visit.

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