Opportunity Information: Apply for RFA ES 12 003

  • The National Institutes of Health in the education environment health sector is offering a public funding opportunity titled "Superfund Hazardous Substance Research and Training Program (P42)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.143 NIEHS Superfund Hazardous SubstancesBasic Research and Education.
  • This funding opportunity was created on Oct 13, 2011 and posted on Oct 13, 2011.
  • Applicants must submit their applications by Apr 10, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $8,500,000.00 to eligible and selected applicants.
  • Eligible applicants include: Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Apply for RFA ES 12 003

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Opportunity Summary:

The Superfund Hazardous Substance Research and Training Program (P42), also known as the NIEHS Superfund Research Program (SRP) Centers, is a National Institutes of Health funding opportunity aimed at building interdisciplinary research centers that tackle real-world hazardous substance problems with a strong emphasis on solutions and practical impact. The program is run by the National Institute of Environmental Health Sciences (NIEHS) and is grounded in the priorities laid out in the Superfund Amendments and Reauthorization Act of 1986. Rather than funding a single standalone project, these awards are designed to support a coordinated center made up of multiple integrated research projects that bring together biomedical and non-biomedical disciplines, along with required supporting cores that help the center function effectively and ensure its work reaches the people and organizations who can use it.

At its core, the opportunity supports research that advances how hazardous substances are detected, understood, and addressed in both human health and environmental contexts. The SRP Centers are expected to push forward advanced techniques for detecting, assessing, and evaluating the effects of hazardous substances on human health, including approaches that improve exposure assessment, toxicology, mechanistic understanding, and health impact evaluation. In parallel, the program prioritizes improved methods for assessing risks to human health posed by hazardous substances, which can include modeling, biomonitoring, dose-response work, and frameworks that connect environmental measurements to likely health outcomes. The scope also explicitly includes environmental detection methods and technologies, meaning innovations in monitoring, sampling, analytical chemistry, sensors, and field-ready tools that can find and characterize contaminants in air, water, soil, sediment, or biological media. Finally, the program supports fundamental biological, chemical, and physical methods that reduce both the amount and toxicity of hazardous substances, which can include remediation strategies, transformation or degradation pathways, containment approaches, and technology development aimed at reducing hazard at its source or after release.

A defining feature of this program is the center structure, which typically includes several integrated research projects plus cores that provide shared functions and help translate science into action. The announcement highlights administrative support as a core function, as well as community engagement, research translation, research support, and training. In practice, this reflects an expectation that SRP Centers do more than publish papers: they should actively connect with affected communities and stakeholders, communicate findings in usable ways, and support the training of the next generation of researchers and professionals who can work at the intersection of environmental contamination and public health. The inclusion of community engagement and research translation as core elements signals that the program values two-way communication, responsiveness to community needs, and the movement of findings into policy, practice, remediation decision-making, and public health interventions.

From an administrative and eligibility standpoint, this is a discretionary grant mechanism (P42) under the NIH umbrella, with activity areas spanning education, environment, and health. The opportunity was posted on October 13, 2011, with an application deadline of April 10, 2012, and an archived date of May 11, 2012. The estimated total funding listed is $8.5 million, and there is no cost sharing or matching requirement. Eligible applicants include public and state-controlled institutions of higher education and private institutions of higher education, along with several categories of institutions specifically called out, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian Serving Institutions. Foreign institutions and other non-U.S. entities are not eligible to apply, and foreign components are not allowed under NIH policy for this opportunity.

For reference and full program details, the announcement is identified as Funding Opportunity Number RFA-ES-12-003, with CFDA numbers 93.113 (Environmental Health) and 93.143 (NIEHS Superfund Hazardous Substances Basic Research and Education). The full text of the funding announcement was made available through the NIH grants guide at http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-12-003.html, and NIH provided webmaster contacts for technical access and linking issues.

Frequently Asked Questions (FAQs)

What is the Superfund Hazardous Substance Research and Training Program (P42)?

The Superfund Hazardous Substance Research and Training Program (P42), also referred to as the NIEHS Superfund Research Program (SRP) Centers, is a National Institutes of Health (NIH) funding opportunity designed to build interdisciplinary research centers that address real-world hazardous substance problems. It emphasizes solutions, practical impact, and getting research into the hands of people and organizations that can use it.

Which NIH institute runs this program?

The program is run by the National Institute of Environmental Health Sciences (NIEHS).

What is the main purpose of the SRP Centers?

The main purpose is to support coordinated, interdisciplinary centers that improve how hazardous substances are detected, understood, evaluated, and addressed across both human health and environmental contexts, with an explicit focus on solution-oriented outcomes and real-world application.

Is this grant meant to fund one research project or a larger center?

This opportunity is designed to fund a coordinated center rather than a single standalone project. SRP Centers are expected to include multiple integrated research projects that work together, supported by required cores that provide shared functions and help the center operate effectively.

What kinds of disciplines are expected to be included in an SRP Center?

SRP Centers are expected to integrate biomedical and non-biomedical disciplines. The intent is to bring together complementary expertise needed to address hazardous substance issues from detection and mechanistic science through risk assessment, remediation, and real-world decision-making.

What research topics and activities are within the scope of this funding opportunity?

The scope includes research that advances detection, assessment, understanding, and solutions for hazardous substances. This includes work spanning exposure assessment, toxicology, mechanisms of action, health impact evaluation, risk assessment methods, environmental monitoring technologies, and approaches to reduce the amount and toxicity of hazardous substances through remediation and related strategies.

What human health research areas are prioritized by the program?

The program prioritizes advanced techniques to detect, assess, and evaluate the effects of hazardous substances on human health. Examples of emphasized areas include improved exposure assessment, toxicology, mechanistic understanding of effects, and evaluation of health impacts.

What risk assessment work is supported under this opportunity?

The opportunity prioritizes improved methods for assessing risks to human health posed by hazardous substances. This can include modeling, biomonitoring, dose-response research, and frameworks that connect environmental measurements to likely health outcomes.

Does the program support environmental monitoring and detection technology development?

Yes. The scope explicitly includes environmental detection methods and technologies, such as innovations in monitoring, sampling, analytical chemistry, sensors, and field-ready tools used to find and characterize contaminants in air, water, soil, sediment, or biological media.

Does the program support remediation and methods to reduce hazardous substances?

Yes. The opportunity supports fundamental biological, chemical, and physical methods that reduce both the amount and toxicity of hazardous substances. This can include remediation strategies, transformation or degradation pathways, containment approaches, and technology development aimed at reducing hazards at the source or after release.

What is the defining structural feature of an SRP Center application?

A defining feature is the center-based structure: multiple integrated research projects plus cores that provide shared support functions and help translate research into action.

What core functions are highlighted for SRP Centers?

The announcement highlights several core functions, including administrative support, community engagement, research translation, research support, and training. These cores help ensure the center is coordinated and that its work reaches stakeholders who can use the findings.

What does the emphasis on community engagement mean in this program?

Community engagement is treated as a core element, signaling an expectation of two-way communication, responsiveness to community needs, and active connection with affected communities and stakeholders rather than only producing academic publications.

What does "research translation" mean in the context of SRP Centers?

Research translation, as described in the opportunity, reflects a focus on communicating findings in usable ways and moving results into practice. This can include informing policy, supporting remediation decision-making, and contributing to public health interventions.

Does this opportunity include a training component?

Yes. Training is identified as a core function, reflecting the expectation that SRP Centers will help train the next generation of researchers and professionals working at the intersection of environmental contamination and public health.

What is the grant mechanism used for this funding opportunity?

This is a discretionary grant mechanism under NIH using the P42 activity code.

What activity areas does this opportunity span?

The activity areas span education, environment, and health.

What is the Funding Opportunity Number for this announcement?

The Funding Opportunity Number is RFA-ES-12-003.

What CFDA numbers are associated with this opportunity?

The CFDA numbers listed are 93.113 (Environmental Health) and 93.143 (NIEHS Superfund Hazardous Substances Basic Research and Education).

When was this funding opportunity posted and when was the application deadline?

The opportunity was posted on October 13, 2011, and the application deadline was April 10, 2012.

Is this funding opportunity still active?

No. The announcement includes an archived date of May 11, 2012, indicating it is no longer active.

How much total funding was estimated for this opportunity?

The estimated total funding listed for this opportunity is $8.5 million.

Is cost sharing or matching required?

No. The opportunity specifies that there is no cost sharing or matching requirement.

What types of organizations are eligible to apply?

Eligible applicants include public and state-controlled institutions of higher education and private institutions of higher education. The announcement also specifically calls out eligibility for several institution categories, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian Serving Institutions.

Are foreign institutions or non-U.S. entities eligible to apply?

No. Foreign institutions and other non-U.S. entities are not eligible to apply for this opportunity.

Are foreign components allowed under this opportunity?

No. The announcement states that foreign components are not allowed under NIH policy for this opportunity.

What law or statutory priorities does the program align with?

The program is grounded in the priorities laid out in the Superfund Amendments and Reauthorization Act of 1986.

Where can applicants find the full text of the funding announcement?

The full text was made available through the NIH grants guide at http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-12-003.html.

Who should be contacted for technical issues accessing or linking to the announcement?

NIH provided webmaster contacts for technical access and linking issues, as referenced in the announcement.

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