Opportunity Information: Apply for CDC RFA PS10 10105
Apply for CDC RFA PS10 10105
- The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Support for the National Government Monitoring and Evaluation System, Surveillance and Laboratory Infrastructure in the Republic of Zambia under the President s Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067 Global AIDS.
- This funding opportunity was created on Feb 26, 2010 and posted on Dec 29, 2009.
- Applicants must submit their applications by Mar 1, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $20,000,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
- The TDRC, situated within the premises of the Ndola Central Hospital, has a mandate to conduct research, training and provide service for diseases of public health importance. The institution has been actively involved in antenatal clinic sentinel surveillance (ANC SS) for HIV and syphilis since the early 1990 s, taking a lead role as a reference laboratory for the northern half of the country. TDRC is part of Zambia s reference laboratory system, functioning as both a regional laboratory and supporting important disease surveillance, such as the sentinel surveillance of HIV and the Demographic Health Survey.
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Opportunity Summary:
This grant opportunity, issued by the U.S. Centers for Disease Control and Prevention (CDC) under the President's Emergency Plan for AIDS Relief (PEPFAR), focuses on strengthening Zambia's national capacity to monitor, evaluate, and respond to HIV/AIDS and related health threats. The overall purpose is to improve how Zambia gathers and uses health data and to reinforce the laboratory systems needed to support surveillance, diagnosis, treatment monitoring, and public health decision-making. While HIV/AIDS is the central priority, the scope also explicitly includes opportunistic infections and neglected tropical diseases, recognizing that these conditions often overlap in the same communities and place additional strain on the health system.
A core feature of the announcement is support for the Tropical Diseases Research Center (TDRC), located at Ndola Central Hospital, which plays an established role in Zambia's public health infrastructure. TDRC has long experience conducting antenatal clinic sentinel surveillance (including HIV and syphilis surveillance dating back to the early 1990s) and serves as a reference laboratory for the northern part of the country. Because it is integrated into Zambia's reference laboratory network and contributes to major surveillance activities such as sentinel surveillance and the Demographic and Health Survey, the award is designed to build on an existing platform rather than create a new one from scratch. In practical terms, the grant seeks to expand and strengthen HIV, sexually transmitted infection (STI), and tuberculosis (TB) surveillance programs, while also improving the laboratory backbone that makes these surveillance efforts credible, timely, and actionable.
Another major emphasis is the improvement of laboratory infrastructure and laboratory support functions that are essential for public health surveillance and clinical care. This includes strengthening lab capacity for diagnosing infections, supporting treatment decisions, monitoring disease progression and response to therapy, and improving HIV screening for blood safety. The blood safety component is especially important because reliable screening protects recipients of transfusions and is a key element of a safe health system, particularly in settings with a significant burden of HIV. By investing in laboratory systems that can consistently generate accurate results, the program aims to improve both routine patient care and the broader quality of national surveillance data.
The opportunity also highlights the importance of turning data into better services, not just collecting information for reporting purposes. It specifically aims to support the use of essential information from multiple sources, including sentinel surveillance platforms, national health surveys, clinical information systems, and targeted evaluations. The idea is to strengthen the full chain from data collection to analysis to decision-making, so that findings can be used to improve program performance and the quality of care. This can include identifying gaps in coverage, spotting outbreaks or shifts in disease patterns earlier, improving how treatment programs are managed, and ensuring that resources are directed to the places and populations where they are most needed.
From an administrative standpoint, this was a discretionary funding opportunity using a cooperative agreement mechanism, meaning CDC would typically expect substantial involvement in planning, coordination, technical guidance, or oversight during implementation rather than issuing a more hands-off grant. The funding activity category is health, with a CFDA listing under 93.067 (Global AIDS). The announcement projected a single award with an estimated total funding amount of $20,000,000. No cost-sharing or matching was required. The opportunity was posted on December 29, 2009, with closing on March 1, 2010, and it was later archived on March 31, 2010. Eligibility was effectively tailored to the context described in the announcement, with TDRC highlighted as the institution with the mandate and operational role to carry out the surveillance and laboratory strengthening activities at the national and regional level.
In summary, the grant was designed to reinforce Zambia's national monitoring and evaluation system and improve surveillance and laboratory infrastructure by expanding HIV/STI/TB surveillance, strengthening laboratory services for diagnosis and disease monitoring, ensuring safer blood screening, and improving the practical use of surveillance and clinical data to raise the quality of care. The intent was not only to generate better data, but to help Zambia use that data to manage HIV/AIDS programs more effectively and respond more quickly and strategically to related public health threats.
Frequently Asked Questions (FAQs)
What is the main goal of this CDC/PEPFAR grant opportunity?
The overall goal is to strengthen Zambia's national capacity to monitor, evaluate, and respond to HIV/AIDS and related health threats by improving how health data are gathered and used, and by reinforcing the laboratory systems that support surveillance, diagnosis, treatment monitoring, and public health decision-making.
Which organization issued this funding opportunity?
The opportunity was issued by the U.S. Centers for Disease Control and Prevention (CDC) under the President's Emergency Plan for AIDS Relief (PEPFAR).
What health areas does the grant focus on?
HIV/AIDS is the central priority. The scope also explicitly includes opportunistic infections and neglected tropical diseases, recognizing overlap in affected communities and the added strain these conditions place on the health system.
What types of surveillance activities are intended to be strengthened?
The announcement emphasizes expanding and strengthening HIV, sexually transmitted infection (STI), and tuberculosis (TB) surveillance programs, building on existing surveillance platforms and national data sources.
Which institution is specifically highlighted to carry out key activities?
The Tropical Diseases Research Center (TDRC), located at Ndola Central Hospital, is highlighted as an institution with an established mandate and operational role to carry out surveillance and laboratory strengthening activities at national and regional levels.
Why is TDRC central to this opportunity?
TDRC is integrated into Zambia's reference laboratory network, serves as a reference laboratory for the northern part of the country, and has long experience conducting antenatal clinic sentinel surveillance (including HIV and syphilis surveillance dating back to the early 1990s). The award is designed to build on this established platform rather than create a new one.
What laboratory system improvements are emphasized?
The opportunity calls for improving laboratory infrastructure and laboratory support functions needed for public health surveillance and clinical care. This includes strengthening capacity to diagnose infections, support treatment decisions, monitor disease progression and response to therapy, and improve HIV screening for blood safety.
How does the grant connect laboratory strengthening to patient care?
By investing in laboratory systems that can consistently generate accurate results, the program aims to improve routine patient care (diagnosis and treatment monitoring) while also improving the quality, timeliness, and actionability of national surveillance data.
What is the role of blood safety in this opportunity?
Blood safety is specifically emphasized through improved HIV screening for blood safety. Reliable screening helps protect transfusion recipients and is presented as a key element of a safe health system, particularly in settings with a significant HIV burden.
Is the opportunity focused only on collecting data for reporting?
No. A major emphasis is turning data into better services. The opportunity highlights strengthening the full chain from data collection to analysis to decision-making so findings can be used to improve program performance and quality of care, not just reporting.
What data sources does the opportunity intend to strengthen or use?
It references using essential information from multiple sources, including sentinel surveillance platforms, national health surveys, clinical information systems, and targeted evaluations.
How might improved data use affect HIV programs and broader public health response?
The announcement describes using data to identify gaps in coverage, spot outbreaks or shifts in disease patterns earlier, improve how treatment programs are managed, and direct resources to the places and populations where they are most needed.
What funding mechanism is used for this opportunity?
This was a discretionary funding opportunity using a cooperative agreement mechanism, meaning CDC would typically expect substantial involvement in planning, coordination, technical guidance, or oversight during implementation.
What is the funding activity category and CFDA listing?
The funding activity category is health, and the CFDA listing is 93.067 (Global AIDS).
How many awards were anticipated and what was the estimated total funding?
The announcement projected a single award with an estimated total funding amount of $20,000,000.
Was cost-sharing or matching required?
No cost-sharing or matching was required.
When was the opportunity posted and when did it close?
It was posted on December 29, 2009, and it closed on March 1, 2010.
Is this opportunity still active?
No. The opportunity was later archived on March 31, 2010.
How was eligibility described in the announcement?
Eligibility was effectively tailored to the context described, with TDRC highlighted as the institution with the mandate and operational role to carry out the surveillance and laboratory strengthening activities.
Does the scope include conditions beyond HIV?
Yes. In addition to HIV/AIDS, the scope explicitly includes opportunistic infections and neglected tropical diseases, and it also references strengthening surveillance for STIs and TB.
What is the practical intent of the grant in one sentence?
To reinforce Zambia's monitoring and evaluation system and strengthen surveillance and laboratory infrastructure so the country can generate better data and use it to manage HIV/AIDS programs more effectively and respond more quickly to related public health threats.
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