Opportunity Information: Apply for CDC RFA GH20 2027

  • The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Support Government of the Kingdom of Eswatini (GKoE) to Provide Comprehensive, Quality Assured Care, Treatment and Prevention HIV/TB Services to Achieve and Sustain Epidemic Control under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
  • This funding opportunity was created on Jan 07, 2020.
  • Applicants must submit their applications by Mar 07, 2020 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 2 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for CDC RFA GH20 2027

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Opportunity Summary:

This funding opportunity is a CDC cooperative agreement under PEPFAR focused on helping the Government of the Kingdom of Eswatini strengthen and sustain HIV and TB epidemic control by improving the quality, reach, and consistency of services delivered through the Ministry of Health. The work is concentrated in two administrative regions, Manzini and Lubombo, and is designed to reinforce routine facility-based care while also extending services and messaging into surrounding communities so more people are reached, linked to care, and retained in treatment over time.

The program is centered on comprehensive HIV service delivery with an emphasis on quality assurance across the entire clinical pathway. That includes HIV testing services and stronger linkages to treatment for those who test positive, with added attention to treatment retention, patient follow-up, and tracking systems that reduce loss to follow-up. It also includes cervical cancer screening for women living with HIV, recognizing the elevated risk in this population and the importance of integrating prevention and early detection into HIV care platforms.

Laboratory strengthening is a major component, particularly viral load testing, which is essential for monitoring treatment effectiveness and achieving viral suppression at scale. The opportunity also covers broader HIV-related laboratory diagnostics needed to support clinical decision-making and timely patient management. Alongside HIV services, the award supports integrated TB prevention, diagnosis, and treatment for people living with HIV, as well as HIV prevention, diagnosis, and treatment services for people with TB. This bidirectional integration is meant to reduce missed opportunities and improve outcomes for co-infected patients.

The opportunity explicitly includes services for priority and vulnerable groups, including pediatric and adolescent HIV/TB programming. It also supports prevention of mother-to-child transmission (PMTCT) services and structured follow-up for HIV-exposed infants, ensuring early infant diagnosis, continuity of care, and rapid initiation of treatment when needed. Additional prevention interventions include voluntary medical male circumcision and pre-exposure prophylaxis, both of which are key PEPFAR-supported strategies for reducing new HIV infections and sustaining epidemic control.

Implementation is expected to occur through direct site-level support to Ministry of Health facilities, paired with community-facing activities. The community component is intended to reinforce demand creation, communication, prevention, and treatment literacy, and to connect populations to services in ways that improve uptake and long-term engagement. A capacity-building focus runs throughout the award: recipients are expected to strengthen facility managers and local leadership so Eswatini national HIV guidelines and programs are implemented consistently and with fidelity, rather than relying indefinitely on external technical direction.

The opportunity also anticipates support for human resources, particularly for positions not covered under the formal government establishment, where staffing gaps could otherwise limit service delivery. In addition, monitoring and evaluation is a required pillar of the work, including strengthening routine data systems and improving data use at supported facilities so performance can be measured, gaps can be identified quickly, and program improvements can be made based on evidence rather than assumptions.

From an administrative standpoint, the opportunity is identified as CDC RFA GH20-2027, offered by the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CGH), with CFDA number 93.067. It is a discretionary funding opportunity using a cooperative agreement mechanism, indicating substantial involvement by CDC in programmatic collaboration and oversight. Eligibility is listed as unrestricted, meaning a wide range of entity types may apply, subject to any additional eligibility clarifications in the full announcement. CDC anticipated making two awards. For budgeting, the notice states that the Year 1 award ceiling is listed as 0 (none), while the approximate total fiscal year funding for Year 1 was anticipated at $15,000,000, contingent on the availability of funds. The opportunity was created January 7, 2020, with an original closing date of March 7, 2020, and applications were due electronically by 11:59 p.m. Eastern Time on the deadline date.

Frequently Asked Questions (FAQs)

1) What is this funding opportunity?

This is a CDC cooperative agreement under PEPFAR focused on helping the Government of the Kingdom of Eswatini strengthen and sustain HIV and TB epidemic control by improving the quality, reach, and consistency of services delivered through the Ministry of Health.

2) Which agency is offering the opportunity?

The opportunity is offered by the U.S. Department of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC), specifically CDC CGH.

3) What is the funding mechanism and what does it imply?

The mechanism is a cooperative agreement. This indicates substantial involvement by CDC in programmatic collaboration and oversight during implementation.

4) What is the opportunity number and CFDA number?

The opportunity is identified as CDC RFA GH20-2027, with CFDA number 93.067.

5) What is the overall goal of the program?

The program aims to strengthen and sustain HIV and TB epidemic control in Eswatini by improving service quality and consistency, reinforcing routine facility-based care, and extending services and messaging into surrounding communities to improve reach, linkage to care, and long-term retention in treatment.

6) Where will the work be implemented?

The work is concentrated in two administrative regions in Eswatini: Manzini and Lubombo.

7) What types of HIV service delivery activities are emphasized?

The program centers on comprehensive HIV service delivery with an emphasis on quality assurance across the full clinical pathway, including HIV testing services, stronger linkage to treatment for those testing positive, and attention to retention, follow-up, and tracking systems to reduce loss to follow-up.

8) Does the opportunity include cervical cancer screening?

Yes. Cervical cancer screening for women living with HIV is included, reflecting the elevated risk in this population and the importance of integrating prevention and early detection into HIV care platforms.

9) What laboratory components are included?

Laboratory strengthening is a major component, particularly viral load testing to monitor treatment effectiveness and support viral suppression at scale. The opportunity also includes broader HIV-related laboratory diagnostics needed for clinical decision-making and timely patient management.

10) How does the opportunity address TB in relation to HIV?

The award supports integrated TB prevention, diagnosis, and treatment for people living with HIV, and also supports HIV prevention, diagnosis, and treatment services for people with TB. This bidirectional integration is intended to reduce missed opportunities and improve outcomes for co-infected patients.

11) Are priority or vulnerable populations included in the scope?

Yes. The opportunity explicitly includes services for priority and vulnerable groups, including pediatric and adolescent HIV/TB programming.

12) Does the program support PMTCT and care for HIV-exposed infants?

Yes. It supports prevention of mother-to-child transmission (PMTCT) services and structured follow-up for HIV-exposed infants, including early infant diagnosis, continuity of care, and rapid initiation of treatment when needed.

13) What HIV prevention interventions are included?

Additional prevention interventions include voluntary medical male circumcision and pre-exposure prophylaxis (PrEP), both described as key PEPFAR-supported strategies for reducing new HIV infections and sustaining epidemic control.

14) What is the expected implementation approach at the facility level?

Implementation is expected to occur through direct site-level support to Ministry of Health facilities.

15) What community-based activities are expected?

The community component is intended to reinforce demand creation, communication, prevention and treatment literacy, and to connect populations to services in ways that improve uptake and long-term engagement.

16) Is capacity building part of the award?

Yes. A capacity-building focus runs throughout the award, with expectations to strengthen facility managers and local leadership so national HIV guidelines and programs are implemented consistently and with fidelity, rather than relying indefinitely on external technical direction.

17) Does the opportunity allow support for human resources?

Yes. The opportunity anticipates support for human resources, particularly for positions not covered under the formal government establishment where staffing gaps could otherwise limit service delivery.

18) What monitoring and evaluation (M&E) requirements are highlighted?

Monitoring and evaluation is a required pillar of the work, including strengthening routine data systems and improving data use at supported facilities so performance can be measured, gaps can be identified quickly, and program improvements can be made based on evidence.

19) Who is eligible to apply?

Eligibility is listed as unrestricted, meaning a wide range of entity types may apply, subject to any additional eligibility clarifications in the full announcement.

20) How many awards did CDC anticipate making?

CDC anticipated making two awards.

21) What was the anticipated total funding for Year 1?

The approximate total fiscal year funding anticipated for Year 1 was $15,000,000, contingent on the availability of funds.

22) What was the Year 1 award ceiling?

The notice states the Year 1 award ceiling was listed as 0 (none).

23) When was the opportunity created and what was the original closing date?

The opportunity was created on January 7, 2020, and had an original closing date of March 7, 2020.

24) How and when were applications due?

Applications were due electronically by 11:59 p.m. Eastern Time on the deadline date.

25) What does the program mean by improving retention and reducing loss to follow-up?

Based on the description, this includes stronger patient follow-up and tracking systems intended to keep patients engaged in care over time and reduce the number of patients who stop attending services after diagnosis or treatment initiation.

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