Opportunity Information: Apply for CDC RFA GH15 1546

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Support Laboratory Diagnosis and Monitoring to Scale up and Improve HIV/AIDS Care and Treatment Services in the Kingdom of Lesotho under the Presidents Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067 Global AIDS.
  • This funding opportunity was created on Sep 17, 2014 and posted on Aug 19, 2014.
  • Applicants must submit their applications by Oct 17, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $1,500,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • Eligible applicants that can apply for this FOA are listed below Government Organizations National Ministries of Health State and local governments or their Bona Fide Agents (this includes the District of Columbia, the Commonwealth of Puerto Rico, the Virgin Islands, the Commonwealth of the Northern Marianna Islands, American Samoa, Guam, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau) . American Indian/Alaska Native tribal governments (federally recognized or state recognized) Political subdivisions of States (in consultation with States) Non government Organizations American Indian/Alaska native tribally designated organizations Alaska Native health corporations Tribal epidemiology centers Urban Indian health organizations Nonprofit with 501C3 IRS status (other than institution of higher education) Nonprofit without 501C3 IRS status (other than institution of higher education) Research institutions (that will perform activities deemed as non research) Colleges and Universities Community based organizations Faith based organizations For profit organizations (other than small business) Hospitals Small, minority, and women owned businesses All Other eligible organizations
Apply for CDC RFA GH15 1546

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Opportunity Summary:

This funding opportunity, issued by the U.S. Centers for Disease Control and Prevention (CDC) under PEPFAR, focuses on strengthening laboratory diagnosis and ongoing disease monitoring to improve HIV/AIDS care and treatment services in the Kingdom of Lesotho. The central aim is to build national laboratory capacity so that HIV programs can expand while maintaining high-quality testing for HIV and related conditions, including tuberculosis (TB) and sexually transmitted infections and opportunistic infections (STI/OIs). In practice, the grant is designed to make laboratory services a stronger, more dependable backbone of prevention, care, and treatment, rather than a separate or inconsistent support function.

A key feature of the opportunity is its alignment with the Lesotho National Laboratory Strategic Plan (NLSP 2013/4 to 2018/19). The work is organized around the NLSPs four pillars: accessibility, reliability, affordability, and sustainability. That means the funded project is expected to help more people reach testing services (including those far from central hospitals), improve the accuracy and consistency of results, manage costs and reduce waste, and ensure Lesotho can maintain and operate the laboratory system over time with local expertise and durable systems.

The FOA emphasizes several concrete activity areas. One major area is strengthening referral testing and building a functional laboratory network, so that specimens can move efficiently from smaller or remote facilities to higher-level labs when more complex testing is needed. Another major area is decentralization through point-of-care testing (POCT), which brings certain tests closer to patients and clinics to reduce delays, speed up clinical decisions, and support timely treatment initiation and monitoring. The announcement also prioritizes laboratory quality improvement, including stronger quality management systems (QMS) across facility levels. This includes pushing toward national systems for accreditation and certification, so quality is not dependent on a single site or a temporary project effort but is standardized and measurable across the country.

In addition to service delivery and quality, the opportunity highlights operational systems that often determine whether laboratories can actually perform. This includes laboratory equipment management and supply chain improvements, aiming to reduce equipment downtime, prevent stockouts of reagents and consumables, and strengthen forecasting, procurement planning, and maintenance. The FOA also calls for improvements in laboratory information and data management systems, recognizing that accurate, timely data is essential for patient care (results reporting and follow-up) and for program management (tracking testing volumes, positivity rates, turnaround times, quality indicators, and overall performance).

The expected outcomes described in the announcement include expanded access to diagnosis and disease monitoring through better referral systems and increased POCT coverage; stronger equipment and supply management so services are not interrupted; and a strengthened QMS at all levels, including establishing or reinforcing national accreditation and certification structures. Another stated outcome is the establishment or strengthening of national laboratory databases and information systems, alongside the development of local capacity so that Lesotho can meet national HIV prevention, care, and treatment targets. Overall, the grant is framed around scaling services while improving performance and building long-term country ownership.

Administratively, this is a discretionary cooperative agreement, meaning CDC expects substantial involvement during implementation rather than acting only as a funder. The FOA number is CDC-RFA-GH15-1546, within CFDA 93.067 (Global AIDS). The opportunity anticipated one award, with an award ceiling of $1,500,000, and it did not require cost sharing or matching. It was originally posted August 19, 2014, with the closing date extended to October 17, 2014, and an archive date of October 26, 2014.

Eligibility was broad and included government entities (such as national ministries of health and state/local governments or their agents), tribal governments and related organizations, nonprofits with or without 501(c)(3) status, research institutions performing non-research activities, colleges and universities, community- and faith-based organizations, hospitals, for-profit organizations (other than small businesses), and small, minority-, and women-owned businesses, among other eligible organizations listed in the announcement. For access issues with the full announcement, the listed contact was the CDC Procurement and Grants Office Technical Information Management Section (PGO TIMS) at 770-488-2700.

Frequently Asked Questions (FAQs)

What is this funding opportunity about?

This CDC funding opportunity under PEPFAR focuses on strengthening laboratory diagnosis and ongoing disease monitoring to improve HIV/AIDS care and treatment services in the Kingdom of Lesotho. The goal is to build national laboratory capacity so HIV programs can expand while maintaining high-quality testing for HIV and related conditions such as tuberculosis (TB) and sexually transmitted infections and opportunistic infections (STI/OIs).

Which country and health programs does the award support?

The work is intended to support HIV/AIDS services in the Kingdom of Lesotho, including the laboratory systems that underpin prevention, care, treatment initiation, and treatment monitoring.

Which U.S. agency is issuing the opportunity, and what program is it under?

The opportunity is issued by the U.S. Centers for Disease Control and Prevention (CDC) under PEPFAR.

What is the central purpose of the project?

The project is designed to make laboratory services a stronger and more dependable backbone of HIV prevention, care, and treatment by improving testing access, quality, operational systems, and long-term country ownership.

How does the project align with Lesotho national plans?

The opportunity is aligned with the Lesotho National Laboratory Strategic Plan (NLSP 2013/4 to 2018/19). Proposed work is organized around the NLSPs four pillars: accessibility, reliability, affordability, and sustainability.

What do the NLSP pillars mean for expected project activities?

The NLSP pillars signal that the funded work is expected to (1) improve access to testing services, including for people far from central hospitals; (2) improve the accuracy and consistency of test results; (3) manage costs and reduce waste; and (4) build durable systems and local expertise so the laboratory system can be maintained over time.

What types of laboratory services and conditions are included?

The FOA emphasizes laboratory diagnosis and disease monitoring for HIV, and also references testing related to TB and STI/OIs as part of maintaining high-quality services for HIV programs.

What is meant by strengthening referral testing and the laboratory network?

It refers to improving how specimens move from smaller or remote facilities to higher-level laboratories when more complex testing is needed, creating a functional laboratory network that supports timely and consistent testing services.

What is decentralization through point-of-care testing (POCT), and why is it prioritized?

Decentralization through POCT means bringing certain tests closer to patients and clinics. This is prioritized to reduce delays, speed up clinical decision-making, and support timely treatment initiation and monitoring.

What does the FOA say about laboratory quality improvement?

The FOA prioritizes laboratory quality improvement by strengthening quality management systems (QMS) across facility levels. It also emphasizes moving toward national systems for accreditation and certification so quality is standardized and measurable countrywide.

Why are accreditation and certification mentioned as part of the work?

The FOA frames accreditation and certification as national structures that help ensure laboratory quality is not dependent on a single site or a temporary project effort, but is instead consistent and measurable across the country.

What operational systems are emphasized beyond testing and quality?

The opportunity highlights operational systems that influence day-to-day laboratory performance, including laboratory equipment management, supply chain improvements, and laboratory information and data management systems.

What is included under equipment management and supply chain improvements?

The FOA calls for activities that reduce equipment downtime, prevent stockouts of reagents and consumables, and strengthen forecasting, procurement planning, and maintenance.

What kinds of data and information systems improvements are expected?

The FOA emphasizes laboratory information and data management systems to support both patient care and program management. This includes accurate and timely results reporting and follow-up, as well as monitoring testing volumes, positivity rates, turnaround times, quality indicators, and overall performance.

What outcomes does the FOA expect from the funded work?

Expected outcomes include expanded access to diagnosis and disease monitoring through better referral systems and increased POCT coverage; stronger equipment and supply management to reduce service interruptions; strengthened QMS at all levels; establishing or reinforcing national accreditation and certification structures; strengthened national laboratory databases and information systems; and increased local capacity to meet national HIV prevention, care, and treatment targets.

What type of award mechanism is this?

This is a discretionary cooperative agreement, which means CDC expects substantial involvement during implementation rather than acting only as a funder.

What is the FOA number and CFDA listing?

The FOA number is CDC-RFA-GH15-1546, and it is within CFDA 93.067 (Global AIDS).

How many awards were anticipated, and what was the maximum award amount?

The opportunity anticipated one award, with an award ceiling of $1,500,000.

Was cost sharing or matching required?

No cost sharing or matching was required.

When was the opportunity posted and when did it close?

The opportunity was originally posted on August 19, 2014. The closing date was extended to October 17, 2014. The archive date was October 26, 2014.

Who was eligible to apply?

Eligibility was broad and included government entities (such as national ministries of health and state/local governments or their agents), tribal governments and related organizations, nonprofits with or without 501(c)(3) status, research institutions performing non-research activities, colleges and universities, community- and faith-based organizations, hospitals, for-profit organizations (other than small businesses), and small, minority-, and women-owned businesses, among other eligible organizations listed in the announcement.

Are for-profit organizations allowed to apply?

Yes. The eligibility list includes for-profit organizations (other than small businesses), and it also references small, minority-, and women-owned businesses among eligible organizations listed in the announcement.

Who should be contacted if there are access issues with the full announcement?

For access issues, the listed contact was the CDC Procurement and Grants Office Technical Information Management Section (PGO TIMS) at 770-488-2700.

What is the big picture goal of the grant in practical terms?

In practical terms, the grant is meant to help laboratory services function as a dependable foundation for HIV prevention, care, and treatment in Lesotho by expanding access while improving performance, standardizing quality, strengthening operational systems, and building long-term country ownership.

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