Opportunity Information: Apply for CDC RFA GH15 1576

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Support the Strengthening and Utilization of Strategic Information Activities in the Republic of South Africa under the Presidents Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067 Global AIDS.
  • This funding opportunity was created on Dec 15, 2014 and posted on Dec 15, 2014.
  • Applicants must submit their applications by Jan 23, 2015 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $5,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $25,000,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • The Human Science Research Council (HSRC)
Apply for CDC RFA GH15 1576

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Opportunity Summary:

This CDC cooperative agreement opportunity under PEPFAR focuses on strengthening South Africa's ability to generate, harmonize, and use high-quality HIV strategic information so that the national response is better targeted, better coordinated, and more effective. The need is framed by the scale and complexity of the epidemic in South Africa, which has the largest number of people living with HIV in the world (estimated at over 6.4 million). The country faces a mixed epidemic affecting the general population as well as key populations, alongside major co-morbidities and overlapping burdens such as tuberculosis (TB), poverty-related illnesses, non-communicable diseases, and violence and injury. The opportunity cites national survey findings indicating adult (15-49) HIV prevalence of about 18.8% and incidence of about 1.72, underscoring the importance of robust surveillance and program monitoring to track trends and measure impact.

At its core, the grant is designed to support and expand the South African Government's ongoing efforts to monitor the epidemic and the performance of HIV prevention, care, and treatment programs, while also assessing health system capacity and needs. PEPFAR South Africa positions strategic information as essential infrastructure for decision-making: better data supports better planning, improved resource allocation, and stronger accountability for results. The work is meant to ensure that PEPFAR investments are guided by reliable evidence, and that national and partner systems can consistently produce the information needed for disease and program monitoring.

The opportunity is explicitly aligned with jointly agreed US Government and South African Government priorities through the Partnership Framework Implementation Plan supporting South Africa's National HIV, STI, and TB Response (covering 2012/13 to 2016/17). That agreement emphasizes South African leadership, alignment to national programs, sustainability, innovation and responsiveness to the epidemics, mutual accountability, multi-sector engagement, gender sensitivity, financial transparency, and partnerships. The strategic information activities funded through this award are intended to help achieve the goals of South Africa's National Strategic Plan for HIV, STIs, and TB (2012-2016), including: reducing new HIV infections by at least 50% through combination prevention; initiating at least 80% of eligible patients on antiretroviral therapy with 70% still alive and on treatment five years after initiation; cutting new TB infections and TB deaths by 50%; and supporting an enabling legal framework that protects and promotes human rights to strengthen NSP implementation.

In practical terms, the scope includes developing, implementing, strengthening, and evaluating a broad set of HIV strategic information activities. These may include, but are not limited to, HIV surveillance systems, population and program surveys, implementation science to determine what works best in real-world settings, rigorous monitoring and evaluation, qualitative studies to understand barriers and facilitators to service uptake and retention, and health systems strengthening activities that improve data collection, data quality, analysis, and use. The emphasis is not only on producing data, but also on building South Africa's capacity to interpret and apply it so program managers and policymakers can respond quickly to emerging trends, geographic hotspots, gaps in service coverage, and challenges such as HIV/TB co-infection.

Administratively, the funding instrument is a CDC cooperative agreement (meaning CDC expects substantial involvement in the technical direction and oversight of the work). The funding opportunity number is CDC RFA GH15-1576 under CFDA 93.067 (Global AIDS). The opportunity anticipated one award, with an estimated total funding level listed as $5,000,000 and an award ceiling listed as $25,000,000 (award floor $0), and it states there is no cost sharing or matching requirement. The original and current application due date was January 23, 2015, with electronic submissions due by 11:59 p.m. Eastern Time, and the announcement was later archived on February 22, 2015. Eligibility was restricted in this announcement to the Human Sciences Research Council (HSRC). The listed CDC contact for access issues was Mary T. Glenshaw (fev5@cdc.gov).

Frequently Asked Questions (FAQs)

What is this funding opportunity about?

This CDC cooperative agreement under PEPFAR focuses on strengthening South Africa's ability to generate, harmonize, and use high-quality HIV strategic information so the national HIV response is better targeted, better coordinated, and more effective.

Which agency and program are sponsoring the opportunity?

The opportunity is sponsored by the U.S. Centers for Disease Control and Prevention (CDC) and is part of PEPFAR. It is listed under CFDA 93.067 (Global AIDS).

What is the funding opportunity number?

The funding opportunity number is CDC RFA GH15-1576.

What type of award is this?

This is a CDC cooperative agreement. That means CDC expects substantial involvement in the technical direction and oversight of the supported work, rather than operating strictly as a hands-off grantmaker.

What geographic area or country is the work focused on?

The work is focused on South Africa.

Why is strategic information being emphasized for South Africa?

The opportunity frames the need around the scale and complexity of South Africa's HIV epidemic, noting it has the largest number of people living with HIV in the world (estimated at over 6.4 million). It also highlights overlapping burdens including tuberculosis (TB), poverty-related illnesses, non-communicable diseases, and violence and injury, which increase the importance of strong surveillance and program monitoring.

What epidemic context is cited in the opportunity?

The opportunity cites national survey findings indicating adult (ages 15-49) HIV prevalence of about 18.8% and incidence of about 1.72, underscoring the importance of robust surveillance and monitoring to track trends and measure impact.

What is meant by "HIV strategic information" in this opportunity?

Strategic information refers to the systems, data, and analytic capacity needed to monitor the HIV epidemic and evaluate prevention, care, and treatment program performance. The goal is not only to produce data, but also to strengthen the ability to interpret and use information for decision-making, planning, and accountability.

What are the main goals of the cooperative agreement?

At its core, the cooperative agreement is designed to support and expand the South African Government's efforts to monitor the HIV epidemic and the performance of HIV prevention, care, and treatment programs, while also assessing health system capacity and needs.

How is the work expected to improve the HIV response?

The opportunity describes strategic information as essential infrastructure for decision-making. Better data is intended to support better planning, improved resource allocation, stronger accountability for results, and the ability to respond quickly to emerging trends, geographic hotspots, and gaps in service coverage.

How does this opportunity relate to PEPFAR investments?

The opportunity states that the work is meant to ensure PEPFAR investments are guided by reliable evidence, and that national and partner systems can consistently produce information needed for disease and program monitoring.

What national or bilateral priorities is the opportunity aligned with?

The opportunity is explicitly aligned with jointly agreed U.S. Government and South African Government priorities through the Partnership Framework Implementation Plan supporting South Africa's National HIV, STI, and TB Response (covering 2012/13 to 2016/17).

What principles are emphasized in the Partnership Framework Implementation Plan?

The opportunity highlights principles including South African leadership, alignment to national programs, sustainability, innovation and responsiveness to the epidemics, mutual accountability, multi-sector engagement, gender sensitivity, financial transparency, and partnerships.

How does this opportunity connect to South Africa's National Strategic Plan (NSP)?

The funded strategic information activities are intended to help achieve goals of South Africa's National Strategic Plan for HIV, STIs, and TB (2012-2016).

Which NSP goals are specifically referenced?

The opportunity references goals including: reducing new HIV infections by at least 50% through combination prevention; initiating at least 80% of eligible patients on antiretroviral therapy with 70% still alive and on treatment five years after initiation; cutting new TB infections and TB deaths by 50%; and supporting an enabling legal framework that protects and promotes human rights to strengthen NSP implementation.

What kinds of activities may be supported under this award?

The scope includes developing, implementing, strengthening, and evaluating a broad set of HIV strategic information activities. Examples listed include HIV surveillance systems, population and program surveys, implementation science to determine what works best in real-world settings, rigorous monitoring and evaluation, qualitative studies on barriers and facilitators to service uptake and retention, and health systems strengthening activities to improve data collection, data quality, analysis, and use.

Is the scope limited only to data collection?

No. The opportunity emphasizes both producing data and building South Africa's capacity to interpret and apply it so program managers and policymakers can respond quickly to needs and trends.

Does the opportunity mention HIV/TB co-infection?

Yes. It specifically notes challenges such as HIV/TB co-infection and positions strategic information as important for identifying and addressing such overlapping issues.

How many awards were anticipated?

The opportunity anticipated one award.

What is the estimated total funding level?

The estimated total funding level listed is $5,000,000.

What is the award ceiling and award floor?

The award ceiling listed is $25,000,000, and the award floor is listed as $0.

Is there a cost sharing or matching requirement?

No. The opportunity states there is no cost sharing or matching requirement.

Who was eligible to apply?

Eligibility was restricted in this announcement to the Human Sciences Research Council (HSRC).

When was the application due?

The original and current application due date was January 23, 2015, with electronic submissions due by 11:59 p.m. Eastern Time.

Is this opportunity still open?

No. The announcement was archived on February 22, 2015.

Who was the CDC contact listed for access issues?

The listed CDC contact for access issues was Mary T. Glenshaw (fev5@cdc.gov).

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