Opportunity Information: Apply for CDC RFA GH13 1341

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Supporting the implementation and capacity building of HIV/AIDS prevention interventions for youth using evidence based approaches in South Africa under the Presidents Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067 Global AIDS.
  • This funding opportunity was created on Feb 28, 2013 and posted on Feb 28, 2013.
  • Applicants must submit their applications by Apr 15, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $30,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $6,000,000.00 in funding.
  • The number of recipients for this funding is limited to 3 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • ELIGIBILITY INFORMATION Eligible Applicants Eligible applicants that can apply for this funding opportunity are listed below Nonprofit with 501C3 IRS status (other than institution of higher education) Nonprofit without 501C3 IRS status (other than institution of higher education) For profit organizations (other than small business) Small, minority, and women owned businesses Universities Colleges Research institutions Hospitals Community based organizations Faith based organizations Federally recognized or state recognized American Indian/Alaska Native tribal governments American Indian/Alaska native tribally designated organizations Alaska Native health corporations Urban Indian health organizations Tribal epidemiology centers State and local governments or their Bona Fide Agents (this includes the District of Columbia, the Commonwealth of Puerto Rico, the Virgin Islands, the Commonwealth of the Northern Marianna Islands, American Samoa, Guam, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau) Political subdivisions of States (in consultation with States) Non domestic (non U.S.) entity A Bona Fide Agent is an agency/organization identified by the state as eligible to submit an application under the state eligibility in lieu of a state application. If applying as a bona fide agent of a state or local government, a legal, binding agreement from the state or local government as documentation of the status is required. Attach with Other Attachment Forms when submitting via www.grants.gov.
Apply for CDC RFA GH13 1341

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Opportunity Summary:

This funding opportunity (CDC RFA GH13-1341) is a PEPFAR-supported cooperative agreement from the U.S. Centers for Disease Control and Prevention focused on strengthening HIV prevention for young people in South Africa using evidence-based approaches. It is framed around the reality that, even though South Africa faces a generalized HIV epidemic, new infections among youth ages 15 to 24 remain unacceptably high. The announcement links this risk to the social and economic pressures many adolescents face, especially poverty and limited hope for the future, which can shape sexual decision-making and make it harder to avoid risk behaviors. The program is designed to address those drivers by improving family- and community-level support for prevention while also building young peoples skills, agency, and long-term outlook.

The core goal is to reduce sexual risk behavior and lower vulnerability to HIV among adolescents and youth by pairing direct youth-focused prevention with strong parent and guardian involvement. A major emphasis is placed on equipping parents and guardians with practical tools to support primary HIV prevention before adolescents become sexually active, including helping families understand, accept, and appropriately use proven prevention services and products. The opportunity specifically highlights voluntary medical male circumcision (VMMC), HIV testing and counseling (HTC), and condoms as key prevention options that parents and caregivers should be able to discuss and encourage in age-appropriate ways. In addition to improving access and uptake of services, the program aims to shift the day-to-day conversations at home so that prevention is reinforced consistently rather than only delivered through schools or clinics.

Another central objective is to strengthen the knowledge and skills of parents and guardians so they can promote positive social norms that support HIV prevention and healthier gender relations. This includes encouraging norms that reduce coercion and inequality, improving communication between caregivers and children, and fostering attitudes that support respect, consent, and shared responsibility for sexual health. The announcement also recognizes the close connection between HIV risk and violence, so it calls for training and support that enables parents and guardians to identify signs and symptoms of child sexual abuse and gender-based violence, and to take appropriate steps to address it. That can involve awareness of warning signs, knowing how to respond safely, connecting families to available services, and reducing stigma that often prevents reporting and help-seeking.

Beyond caregiver capacity, the opportunity includes objectives aimed directly at adolescents and youth, with a clear focus on development and resilience. It calls for creating supportive home and community environments that increase adolescents self-efficacy, meaning their confidence and ability to make and stick to safer choices. The desired outcomes include delaying sexual debut, preventing sexually transmitted infections, and reducing unintended pregnancies. Youth programming is expected to help young people work through key developmental tasks such as building individuality, establishing identity and self-acceptance, exploring adult roles, and navigating peer affiliation in healthier ways. In practice, this points to structured, evidence-based interventions that build decision-making skills, communication and refusal skills, and the ability to manage peer pressure, all within a supportive context that includes family engagement.

A distinctive feature of the announcement is its emphasis on future orientation as a prevention strategy. It specifically calls for helping youth imagine a positive future and connect current choices to long-term goals, including making it easier for them to identify how present-day risk behaviors can block education, employment, stable relationships, and other markers of successful adulthood. The underlying prevention logic is that when young people can see realistic pathways to a better future and feel supported by adults around them, they are more likely to reduce sexual risk behaviors and adopt safer practices. This focus reflects a broader approach to HIV prevention that combines biomedical tools and services with behavioral and structural supports that shape real-world decision-making.

From an administrative standpoint, the opportunity was posted February 28, 2013 and closed April 15, 2013, with an archive date of May 15, 2013. It was offered as a discretionary cooperative agreement in the health category under CFDA 93.067 (Global AIDS). CDC anticipated up to three awards, with an estimated total funding amount of $30,000,000 and an award ceiling of $6,000,000. There was no cost-sharing or matching requirement. The eligibility pool was broad, including U.S. and non-U.S. entities, nonprofits (with or without 501(c)(3) status), for-profit organizations (excluding small business in one category but including small, minority-, and women-owned businesses), universities and colleges, research institutions, hospitals, community- and faith-based organizations, and various government and tribal entities. Overall, the grant is structured to support organizations capable of implementing and scaling evidence-based youth HIV prevention programming while simultaneously building the capacity of parents, guardians, and communities to sustain prevention gains over time.

Frequently Asked Questions (FAQs)

What is CDC RFA GH13-1341?

CDC RFA GH13-1341 is a PEPFAR-supported funding opportunity from the U.S. Centers for Disease Control and Prevention (CDC). It is structured as a discretionary cooperative agreement and focuses on strengthening HIV prevention for adolescents and youth in South Africa using evidence-based approaches.

What problem is this opportunity trying to address?

The opportunity targets the persistently high level of new HIV infections among young people ages 15 to 24 in South Africa. It links elevated risk to social and economic pressures affecting adolescents (including poverty and limited hope for the future), which can influence sexual decision-making and make it harder to avoid risk behaviors.

Who is the primary target population?

The primary focus is adolescents and youth ages 15 to 24 in South Africa. The program also places major emphasis on parents and guardians, because caregiver involvement is central to the prevention strategy described in the announcement.

What is the overall goal of the program?

The core goal is to reduce sexual risk behavior and lower vulnerability to HIV among adolescents and youth by pairing direct youth-focused prevention programming with strong parent and guardian involvement.

How does the opportunity involve parents and guardians?

A major emphasis is placed on equipping parents and guardians with practical tools to support primary HIV prevention before adolescents become sexually active. This includes strengthening caregiver knowledge, improving caregiver-child communication, and helping families understand, accept, and appropriately use proven prevention services and products.

Which HIV prevention services or products are specifically highlighted?

The announcement specifically highlights voluntary medical male circumcision (VMMC), HIV testing and counseling (HTC), and condoms as key prevention options that parents and caregivers should be able to discuss and encourage in age-appropriate ways.

Is the program only about improving clinic or school-based service delivery?

No. While improving access and uptake of services is part of the approach, the opportunity also aims to shift day-to-day conversations and reinforcement of prevention within the home so that prevention messaging and support are consistent and not limited to schools or clinics.

What kinds of changes in family or community norms does the program aim to support?

The program aims to strengthen parents and guardians so they can promote positive social norms that support HIV prevention and healthier gender relations. This includes encouraging norms that reduce coercion and inequality and fostering attitudes supporting respect, consent, and shared responsibility for sexual health.

How does the opportunity address gender-based violence and child sexual abuse?

The announcement recognizes a close connection between HIV risk and violence. It calls for training and support that enables parents and guardians to identify signs and symptoms of child sexual abuse and gender-based violence and to take appropriate steps to address it, such as responding safely, connecting families to available services, and reducing stigma that can prevent reporting and help-seeking.

What outcomes for adolescents and youth are mentioned?

The desired outcomes include creating supportive home and community environments that increase adolescents' self-efficacy, delaying sexual debut, preventing sexually transmitted infections, and reducing unintended pregnancies.

What is meant by building "self-efficacy" for youth in this program?

In this announcement, self-efficacy refers to adolescents' confidence and ability to make and stick to safer choices. The program envisions supportive environments and interventions that help youth practice and maintain safer decision-making.

What kinds of youth development topics does the opportunity expect programs to address?

Youth programming is expected to support key developmental tasks, including building individuality, establishing identity and self-acceptance, exploring adult roles, and navigating peer affiliation in healthier ways.

What types of skills are youth-focused interventions expected to build?

The opportunity points to structured, evidence-based interventions that build decision-making skills, communication and refusal skills, and the ability to manage peer pressure, within a supportive context that includes family engagement.

What does "future orientation" mean in this funding opportunity?

Future orientation is emphasized as a prevention strategy. The announcement calls for helping youth imagine a positive future and connect current choices to long-term goals, including understanding how present-day risk behaviors can block education, employment, stable relationships, and other markers of successful adulthood.

Why does the announcement emphasize future orientation as part of HIV prevention?

The prevention logic described is that when young people can see realistic pathways to a better future and feel supported by adults around them, they are more likely to reduce sexual risk behaviors and adopt safer practices.

What type of award mechanism is used?

This opportunity is a discretionary cooperative agreement.

What is the CFDA number and program category?

The opportunity is listed under CFDA 93.067 (Global AIDS) and is in the health category.

When was the opportunity posted and when did it close?

It was posted on February 28, 2013 and closed on April 15, 2013. The archive date is May 15, 2013.

How many awards did CDC anticipate making?

CDC anticipated up to three awards.

What was the estimated total funding amount?

The estimated total funding amount was $30,000,000.

What was the award ceiling?

The award ceiling was $6,000,000.

Was cost sharing or matching required?

No. The announcement states there was no cost-sharing or matching requirement.

Who was eligible to apply?

Eligibility was broad and included U.S. and non-U.S. entities; nonprofits (with or without 501(c)(3) status); for-profit organizations (including small, minority-, and women-owned businesses, with one category excluding small business); universities and colleges; research institutions; hospitals; community- and faith-based organizations; and various government, tribal, and related entities.

Does the opportunity allow non-U.S. organizations to apply?

Yes. The eligibility pool explicitly includes non-U.S. entities.

What kinds of organizations does this opportunity appear designed to support?

Based on the announcement description, it is designed to support organizations capable of implementing and scaling evidence-based youth HIV prevention programming while also building capacity among parents, guardians, and communities to sustain prevention gains over time.

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