Opportunity Information: Apply for PAR 15 333
Apply for PAR 15 333
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Sustained Support for Informatics Resources for Cancer Research and Management (U24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.396 Cancer Biology Research.
- This funding opportunity was created on Aug 18, 2015 and posted on Aug 18, 2015.
- Applicants must submit their applications by Jun 14, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Independent school districts Small businesses County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education City or township governments Special district governments Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education State governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Sustained Support for Informatics Resources for Cancer Research and Management (U24) opportunity (Funding Opportunity Number PAR 15-333) is a National Institutes of Health cooperative agreement aimed at keeping valuable cancer informatics resources strong, usable, and available over time. Rather than paying to invent brand-new tools from scratch, this FOA is designed to support the continued operation and improvement of existing informatics tools and resources that are already widely adopted by the cancer research community. It sits within the National Cancer Institute (NCI) Informatics Technology for Cancer Research (ITCR) Program, which covers the full lifecycle of informatics technology, and this particular announcement targets the sustainment phase: maintaining, hardening, updating, and improving tools so they keep delivering value as science, data types, and user expectations evolve.
The core purpose is to ensure that high-value informatics resources can continue to serve current and emerging needs across the entire cancer research continuum. That includes cancer biology, diagnosis and treatment, prevention, cancer control and epidemiology, and research focused on cancer health disparities. In practical terms, this means applicants are expected to propose work that improves user experience, reliability, accessibility, and overall availability of a resource that the community already depends on. Typical sustainment-oriented activities under a program like this often include improving documentation and onboarding materials, enhancing performance and scalability, strengthening security and privacy protections when relevant, modernizing codebases and infrastructure, providing user support and training, ensuring interoperability with new data standards or platforms, and implementing processes that keep the resource stable and responsive over multiple years.
Because this is a U24 cooperative agreement, awardees should expect an ongoing partnership-style relationship with NIH/NCI staff rather than a hands-off grant. Cooperative agreements generally involve substantial programmatic involvement by the funding agency, which often translates into more active coordination, clearer milestones, regular progress reporting, and alignment with broader program goals. The announcement emphasizes that a successful application needs a convincing sustainment plan, including clear justification for why the resource should be maintained and evidence that it has benefited the cancer research field already. It is not enough to argue that a tool is useful in theory; applicants are expected to show demonstrated value and articulate how that value will continue or grow if the resource is supported.
A key theme in the FOA is community engagement and value assessment. Applicants are asked to describe mechanisms for assessing and maximizing the value of the resource to researchers, which usually means having concrete ways to measure usage, impact, and satisfaction. This could involve tracking adoption metrics, gathering user feedback, documenting scientific outputs enabled by the resource, monitoring support requests and resolution times, and using advisory boards or community governance models to prioritize improvements. The FOA also highlights the importance of collaboration and deep engagement between the resource team and the target research community. In other words, the resource should not operate in isolation; it should evolve in active dialogue with the scientists, clinicians, and data users it serves, with structured pathways for the community to influence the roadmap.
From an administrative standpoint, the opportunity is classified as discretionary funding and falls under the education/health funding activity category, with CFDA number 93.396 (Cancer Biology Research). There is no cost sharing or matching requirement. The FOA was posted on August 18, 2015, with an original and current closing date of June 14, 2018, and an archive date of July 15, 2018, meaning it is no longer open for applications but is still useful as a reference point for the kinds of sustainment activities NCI has sought to fund under ITCR.
Eligibility is broad across U.S.-based organizations, spanning many types of public and private entities. Eligible applicants include nonprofits (with or without 501(c)(3) status), public and private institutions of higher education, small businesses, for-profit organizations other than small businesses, and various levels of government (state, county, city/township, special district). The FOA also explicitly includes a range of mission-focused and federally recognized categories such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, and other designated serving institutions. Foreign institutions and non-U.S. components of U.S. organizations are not eligible to apply, although foreign components as defined by the NIH Grants Policy Statement are allowed, which typically means a U.S. applicant may include certain foreign collaborations or elements when justified and permitted under NIH policy.
Overall, PAR 15-333 is best understood as a sustainment and stewardship funding mechanism for proven cancer informatics resources. The FOA prioritizes keeping widely used tools dependable and improving them in ways that make them easier to use, easier to access, and more aligned with the evolving needs of cancer researchers, while requiring applicants to back up the request with evidence of impact, a realistic long-term plan, and clear strategies for measuring value and staying deeply connected to the user community.
Frequently Asked Questions (FAQs)
What is the PAR 15-333 opportunity (U24) about?
PAR 15-333, titled "Sustained Support for Informatics Resources for Cancer Research and Management (U24)," is an NIH cooperative agreement focused on sustaining high-value cancer informatics resources over time. The emphasis is on keeping proven resources strong, usable, and available, rather than creating brand-new tools from scratch.
What is the main goal of this funding opportunity?
The goal is to ensure that widely adopted cancer informatics tools and resources continue to meet current and emerging needs across the cancer research continuum by maintaining, updating, improving, and operating them reliably over multiple years.
Is this funding meant for building new informatics tools?
No. This FOA is designed to support the continued operation and improvement of existing informatics tools and resources that are already widely adopted by the cancer research community.
Which NIH institute and program does this FOA relate to?
This opportunity sits within the National Cancer Institute (NCI) Informatics Technology for Cancer Research (ITCR) Program. It targets the sustainment phase of the informatics technology lifecycle.
What does "sustainment phase" mean in the context of this FOA?
In this FOA, sustainment refers to maintaining, hardening, updating, and improving an existing resource so it stays reliable, accessible, and useful as science, data types, platforms, and user expectations evolve.
What kinds of research areas can the supported informatics resources serve?
The FOA aims to support resources that serve needs across the entire cancer research continuum, including cancer biology, diagnosis and treatment, prevention, cancer control and epidemiology, and cancer health disparities research.
What types of activities are typically aligned with sustainment under this FOA?
Activities commonly associated with sustainment in this FOA include improving user experience, reliability, accessibility, and overall availability. Examples mentioned include strengthening documentation and onboarding, enhancing performance and scalability, improving security and privacy protections when relevant, modernizing codebases and infrastructure, providing user support and training, ensuring interoperability with evolving data standards or platforms, and implementing processes that keep the resource stable and responsive over time.
What makes a U24 a "cooperative agreement" rather than a standard grant?
A U24 cooperative agreement typically involves substantial programmatic involvement by NIH/NCI staff. Awardees should expect an ongoing partnership-style relationship, which often includes active coordination, clearer milestones, regular progress reporting, and alignment with broader program goals.
What does the FOA expect applicants to show about their resource's value?
Applicants are expected to provide evidence that the resource has already benefited the cancer research field and to justify why it should be maintained. The FOA indicates it is not sufficient to claim theoretical usefulness; demonstrated value is expected.
What is meant by "community engagement" in this FOA?
Community engagement refers to deep collaboration and ongoing interaction between the resource team and the target research community. The FOA highlights that the resource should evolve in active dialogue with the users it serves and provide structured ways for the community to influence priorities and the roadmap.
How are applicants expected to assess and maximize the resource's value?
The FOA asks applicants to describe mechanisms to assess and maximize value to researchers. Examples described include tracking adoption and usage metrics, collecting user feedback, documenting scientific outputs enabled by the resource, monitoring support requests and resolution times, and using advisory boards or community governance models to guide improvements.
What are the administrative classifications for this opportunity?
The opportunity is described as discretionary funding in the education/health funding activity category, with CFDA number 93.396 (Cancer Biology Research).
Is cost sharing or matching required?
No. The FOA states there is no cost sharing or matching requirement.
Is this funding opportunity still open for applications?
No. The FOA was posted on August 18, 2015, with an original and current closing date of June 14, 2018, and an archive date of July 15, 2018. This indicates it is no longer open for applications, though it can still serve as a reference for sustainment activities NCI has sought to fund.
Who is eligible to apply?
Eligibility is broad across U.S.-based organizations. Eligible applicants include nonprofits (with or without 501(c)(3) status), public and private institutions of higher education, small businesses, for-profit organizations other than small businesses, and government entities at multiple levels (state, county, city/township, and special district).
Are specific institution types explicitly included in eligibility?
Yes. The FOA explicitly includes mission-focused and federally recognized categories such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, and other designated serving institutions.
Can foreign institutions apply?
No. Foreign institutions and non-U.S. components of U.S. organizations are not eligible to apply under this FOA.
Are any foreign collaborations allowed at all?
Yes. While foreign institutions cannot apply directly, foreign components (as defined by the NIH Grants Policy Statement) are allowed. This typically means a U.S. applicant may include certain foreign collaborations or elements when justified and permitted under NIH policy.
What is the big-picture takeaway for PAR 15-333?
PAR 15-333 is best understood as sustainment and stewardship funding for proven cancer informatics resources. It prioritizes keeping widely used tools dependable and improving them to be easier to use, easier to access, and better aligned with evolving community needs, with clear expectations for evidence of impact, a realistic sustainment plan, value measurement strategies, and strong community engagement.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 15 333) also looked into and applied for these:
| Funding Opportunity |
|---|
| Development of Innovative Informatics Methods and Algorithms for Cancer Research and Management (R21) Apply for PAR 15 334 Funding Number: PAR 15 334 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Exploratory Multi site Palliative Care Research in Diverse Populations Utilizing the Palliative Care Research Cooperative (PCRC) Group (R21) Apply for PAR 15 337 Funding Number: PAR 15 337 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| NIDA Translational Avant Garde Award for Development of Medication to Treat Substance Use Disorders (UG3/UH3) Apply for RFA DA 16 008 Funding Number: RFA DA 16 008 Agency: National Institutes of Health Category: Education Health Funding Amount: $1,000,000 |
| NCI Exploratory/Developmental Research Grant Program (NCI Omnibus R21) Apply for PAR 15 340 Funding Number: PAR 15 340 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Research Centers for Cancer Systems Biology Consortium(U54) Apply for RFA CA 15 014 Funding Number: RFA CA 15 014 Agency: National Institutes of Health Category: Education Health Funding Amount: $1,500,000 |
| Coordinating Center for Cancer Systems Biology Consortium (U24) Apply for RFA CA 15 015 Funding Number: RFA CA 15 015 Agency: National Institutes of Health Category: Education Health Funding Amount: $750,000 |
| Behavioral Pharmacology and Genetics Translating and Targeting Individual Differences (R03) Apply for RFA DA 09 016 Funding Number: RFA DA 09 016 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Biosignatures of Chronic Drug Exposure (R21) Apply for RFA DA 09 022 Funding Number: RFA DA 09 022 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Drug Abuse Epidemiology and Services Research in Cooperation with the Clinical and Translational Science Awards Consortium (R01) Apply for PAS 09 001 Funding Number: PAS 09 001 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Small Grants Program for Cancer Epidemiology (R03) Apply for PAR 08 237 Funding Number: PAR 08 237 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Unique Interactions Between Tobacco Use and HIV/AIDS (R01) Apply for PA 08 253 Funding Number: PA 08 253 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Unique Interactions Between Tobacco Use and HIV/AIDS (R03) Apply for PA 08 254 Funding Number: PA 08 254 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Health Services Research on the Prevention and Treatment of Drug and Alcohol Abuse (R01) Apply for PA 08 263 Funding Number: PA 08 263 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Small Grants for Behavioral Research in Cancer Control (R03) Apply for PAR 09 003 Funding Number: PAR 09 003 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Understanding the Effects of Emerging Cellular, Molecular, and Genomic Technologies on Cancer Health Care Delivery(R01) Apply for PA 09 004 Funding Number: PA 09 004 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Understanding the Effects of Emerging Cellular, Molecular, and Genomic Technologies on Cancer Health Care Delivery (R21) Apply for PA 09 005 Funding Number: PA 09 005 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Health Services Research on the Prevention and Treatment of Drug and Alcohol Abuse (R21) Apply for PA 08 264 Funding Number: PA 08 264 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Health Services Research on the Prevention and Treatment of Drug and Alcohol Abuse (R03) Apply for PA 08 265 Funding Number: PA 08 265 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Exploratory Studies in Cancer Detection, Diagnosis, and Prognosis (R21) Apply for PA 08 267 Funding Number: PA 08 267 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Interactions between Physical Activity and Drug Abuse (R01) Apply for RFA DA 09 013 Funding Number: RFA DA 09 013 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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