Opportunity Information: Apply for DE FOA 0001458

  • The PAMS-SC in the science and technology and other research and development sector is offering a public funding opportunity titled "Systems Biology Enabled Research on the Roles of Microbial Communities in Carbon Cycle Processes" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 81.049.
  • This funding opportunity was created on Nov 23, 2015 and posted on Nov 23, 2015.
  • Applicants must submit their applications by Mar 23, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $1,250,000.00 in funding.
  • The number of recipients for this funding is limited to 100 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for DE FOA 0001458

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Opportunity Summary:

The Department of Energy (DOE), through the Office of Science (SC) and its Office of Biological and Environmental Research (BER), issued this grant opportunity to fund research that advances the DOE Genomic Science program. The focus is on understanding how microbial communities drive key parts of the carbon cycle, especially in terrestrial environments, using systems biology and modern "omics" approaches. In practical terms, the opportunity targets projects that can explain, at a mechanistic level, how microbes and microbial communities regulate carbon transformations in soils and plant-associated environments, and how those processes affect broader biogeochemical cycling.

The announcement (Funding Opportunity Number DE-FOA-0001458) specifically solicits two main categories of work. The first is systems biology research aimed at mapping and understanding regulatory and metabolic networks in individual microbes, microbial consortia, and microbe-plant interactions that influence carbon cycling. This includes studying how genes, proteins, metabolites, and regulatory pathways work together to control microbial activity related to carbon uptake, breakdown, storage, and release. The second category emphasizes the development and application of omics-based approaches (such as genomics, transcriptomics, proteomics, metabolomics, and related computational analyses) to investigate functional processes in microbial communities that participate in carbon cycling in terrestrial ecosystems. In other words, the DOE is looking for proposals that not only generate large-scale molecular data but also use those data to identify and explain what microbial communities are doing and how they do it in real environmental contexts.

From an administrative standpoint, this is a discretionary grant program in the Science and Technology and other Research and Development category, listed under CFDA 81.049. Eligibility is described as unrestricted, meaning the opportunity is broadly open to applicant types, subject to any additional eligibility details that might be specified in the full announcement text. The FOA was created and posted on November 23, 2015, with an application deadline of March 23, 2016.

In terms of scale, the opportunity lists an award ceiling of $1,250,000 per award and an expected number of awards of 100. The sponsoring agency is identified as PAMS-SC (within DOE). Overall, the intent is to strengthen predictive and mechanistic understanding of microbially mediated carbon cycle processes by funding research that integrates systems-level biological insight with high-throughput molecular measurements, particularly in soil and plant-associated ecosystems where microbial activity strongly influences carbon storage and greenhouse gas dynamics.

Frequently Asked Questions (FAQs)

What is the funding opportunity number for this grant?

The Funding Opportunity Number (FOA) is DE-FOA-0001458.

Which agency is offering this grant opportunity?

This opportunity is issued by the U.S. Department of Energy (DOE) through the Office of Science (SC), specifically its Office of Biological and Environmental Research (BER).

What program is this funding intended to support?

The funding is intended to advance the DOE Genomic Science program by supporting research on how microbial communities drive key parts of the carbon cycle, especially in terrestrial environments.

What is the main scientific focus of the opportunity?

The main focus is mechanistic understanding of how microbes and microbial communities regulate carbon transformations in soils and plant-associated environments, and how those microbially mediated processes influence broader biogeochemical cycling.

What environments or ecosystems are emphasized?

The announcement emphasizes terrestrial ecosystems, with particular attention to soils and plant-associated environments where microbial activity can strongly affect carbon storage and greenhouse gas dynamics.

What are the two main categories of work being solicited?

The FOA solicits two primary categories:

  • Systems biology research focused on mapping and understanding regulatory and metabolic networks in individual microbes, microbial consortia, and microbe-plant interactions that influence carbon cycling.
  • Development and application of omics-based approaches (and related computational analyses) to investigate functional processes in microbial communities participating in carbon cycling in terrestrial ecosystems.

What does the FOA mean by "systems biology research" in this context?

In this FOA, systems biology research refers to work that maps and explains regulatory and metabolic networks that govern microbial activity related to carbon cycling. This includes mechanistic studies of how genes, proteins, metabolites, and regulatory pathways act together to control carbon uptake, breakdown, storage, and release.

What types of biological interactions are in scope for the systems biology category?

The systems biology category explicitly includes individual microbes, microbial consortia, and microbe-plant interactions, as long as the work targets mechanisms relevant to carbon cycling.

What does the FOA mean by "omics-based approaches"?

The FOA describes omics-based approaches as methods such as genomics, transcriptomics, proteomics, metabolomics, and related computational analyses used to investigate functional processes in microbial communities involved in carbon cycling.

Is the FOA only looking for large-scale data generation?

No. While the opportunity includes high-throughput molecular measurements, it emphasizes using those data to identify and explain what microbial communities are doing and how they do it in real environmental contexts.

What kinds of carbon-cycle processes are highlighted?

The FOA highlights microbial processes related to carbon uptake, breakdown, storage, and release, and how those processes connect to broader biogeochemical cycling.

What is the assistance listing (CFDA) number associated with this opportunity?

The opportunity is listed under CFDA 81.049.

What type of grant program is this?

This is described as a discretionary grant program in the Science and Technology and other Research and Development category.

Who is eligible to apply?

Eligibility is described as unrestricted, meaning it is broadly open to applicant types, subject to any additional eligibility details that may be specified in the full announcement text.

Which DOE office is identified as the sponsoring agency?

The sponsoring agency is identified as PAMS-SC within DOE.

When was the FOA posted?

The FOA was created and posted on November 23, 2015.

What is the application deadline?

The application deadline is March 23, 2016.

What is the maximum award amount (award ceiling) per award?

The award ceiling is $1,250,000 per award.

How many awards does DOE expect to make?

The expected number of awards is 100.

What is the overall intent of this funding opportunity?

The overall intent is to strengthen predictive and mechanistic understanding of microbially mediated carbon cycle processes by supporting research that integrates systems-level biological insight with high-throughput molecular measurements, particularly in soil and plant-associated ecosystems.

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