Opportunity Information: Apply for PAR 11 315

  • The National Institutes of Health in the education environment health income security and social services sector is offering a public funding opportunity titled "Systems Science and Health in the Behavioral and Social Sciences (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.121 Oral Diseases and Disorders Research 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.361 Nursing Research 93.837 Cardiovascular Diseases Research 93.859 Biomedical Research and Research Training 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research.
  • This funding opportunity was created on Nov 21, 2014 and posted on Aug 17, 2011.
  • Applicants must submit their applications by Nov 21, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education County governments Special district governments State governments Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Native American tribal governments (Federally recognized) City or township governments Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

Systems Science and Health in the Behavioral and Social Sciences (R21) is an NIH Funding Opportunity Announcement designed to support early-stage, exploratory research that applies systems science approaches to questions in human health that are fundamentally behavioral and/or social in nature. Led by the Office of Behavioral and Social Sciences Research (OBSSR) and joined by multiple NIH Institutes and Centers (including NHLBI, NIA, NIAAA, NIBIB, NICHD, NIDCR, NIEHS, NIGMS, NIMH, and NINR), the opportunity is meant to broaden how researchers study complex health problems by encouraging projects that explicitly treat health-related behavior and social conditions as dynamic, interconnected systems rather than isolated factors.

The core focus is on developing and testing basic or applied research projects, including methodological work, that make systems science the central analytic strategy. In practice, this means proposals are expected to use tools such as system dynamics modeling, agent-based modeling, network analysis, simulation modeling, or other formal systems methods that can represent feedback loops, non-linear relationships, adaptation over time, multi-level influences (individual, family, community, policy), and interactions across domains. The FOA emphasizes that the work should be relevant to behavioral and social sciences and health, and it is explicitly intended to expand the range of topics addressed with systems methods beyond what might be covered under other standing NIH announcements.

The award mechanism is the NIH R21, which is typically used for exploratory or developmental projects where investigators are testing new ideas, building models, piloting systems-based methods, or generating proof-of-concept evidence that can support later, larger-scale research. The listed award ceiling is $200,000, and the funding instrument is a grant. The activity categories connected to the announcement span education, environment, health, and income security/social services, reflecting the expectation that systems approaches can cut across traditional boundaries and capture how upstream social and environmental conditions shape downstream health outcomes and behaviors.

Eligibility is broad and includes a wide range of U.S. and non-U.S. entities. Eligible applicants include public and private institutions of higher education, nonprofit organizations (both with and without 501(c)(3) status), for-profit organizations (other than small businesses, though small businesses are also listed as eligible), and multiple levels of government (state, county, city/township, special district). The FOA also highlights eligibility for tribal governments and tribal organizations, public housing authorities/Indian housing authorities, independent school districts, and a variety of mission-focused institutions and organizations such as HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and tribally controlled colleges and universities. Foreign institutions are eligible to apply, and foreign components of U.S. organizations are allowed as defined by NIH policy. There is no cost sharing or matching requirement.

Administratively, the opportunity is identified as PAR-11-315 and is categorized as a discretionary grant program. It was posted on August 17, 2011, with an original closing date of September 7, 2014, and a final listed closing date of November 21, 2014, after which it was archived (archive date December 21, 2014). The full announcement and official requirements were provided through the NIH Grants Guide at the linked page: http://grants.nih.gov/grants/guide/pa-files/PAR-11-315.html. For access or technical issues with the online announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster (FBOWebmaster@OD.NIH.GOV).

Frequently Asked Questions (FAQs)

What is the "Systems Science and Health in the Behavioral and Social Sciences (R21)" opportunity?

This is an NIH Funding Opportunity Announcement (FOA) intended to support early-stage, exploratory research that applies systems science approaches to human health questions that are fundamentally behavioral and/or social in nature.

Which NIH office leads this FOA?

The opportunity is led by the NIH Office of Behavioral and Social Sciences Research (OBSSR).

Which other NIH Institutes and Centers participate in this announcement?

Multiple NIH Institutes and Centers are involved, including NHLBI, NIA, NIAAA, NIBIB, NICHD, NIDCR, NIEHS, NIGMS, NIMH, and NINR.

What is the main goal of this FOA?

The goal is to broaden how researchers study complex health problems by encouraging projects that treat health-related behavior and social conditions as dynamic, interconnected systems rather than isolated factors.

What kinds of research projects does the FOA support?

The FOA supports basic research or applied research projects, including methodological work, where systems science is the central analytic strategy.

What does it mean that systems science must be the "central analytic strategy"?

It means the proposal is expected to use formal systems methods as the core approach for analysis, rather than treating systems tools as a minor or secondary add-on.

What systems science methods are specifically mentioned as examples?

The FOA mentions approaches such as system dynamics modeling, agent-based modeling, network analysis, simulation modeling, and other formal systems methods.

What types of complexity should the proposed systems methods be able to represent?

The FOA highlights the ability to represent feedback loops, non-linear relationships, adaptation over time, multi-level influences (for example, individual, family, community, and policy), and interactions across domains.

What is the funding mechanism for this opportunity?

The award mechanism is the NIH R21.

What is an NIH R21 typically used for?

An R21 is typically used for exploratory or developmental projects, such as testing new ideas, building models, piloting systems-based methods, or generating proof-of-concept evidence that can support later, larger-scale research.

What is the award ceiling listed for this FOA?

The listed award ceiling is $200,000.

What type of funding instrument is used?

The funding instrument is a grant.

What activity categories are associated with this announcement?

The activity categories connected to the announcement span education, environment, health, and income security/social services.

Why does the FOA include activity categories like education, environment, and social services?

The FOA reflects the expectation that systems approaches can cut across traditional boundaries and capture how upstream social and environmental conditions shape downstream health outcomes and behaviors.

Who is eligible to apply?

Eligibility is broad and includes a wide range of U.S. and non-U.S. entities.

Are U.S. institutions of higher education eligible?

Yes. Eligible applicants include public and private institutions of higher education.

Are nonprofit organizations eligible?

Yes. Both nonprofit organizations with 501(c)(3) status and nonprofit organizations without 501(c)(3) status are listed as eligible.

Are for-profit organizations eligible?

Yes. For-profit organizations are listed as eligible (including entities other than small businesses), and small businesses are also listed as eligible.

Are government entities eligible to apply?

Yes. Eligible applicants include multiple levels of government, such as state governments, county governments, city or township governments, and special district governments.

Are tribal governments and tribal organizations eligible?

Yes. The FOA highlights eligibility for tribal governments and tribal organizations.

Are public housing authorities eligible?

Yes. Public housing authorities and Indian housing authorities are listed as eligible.

Are school districts eligible?

Yes. Independent school districts are listed as eligible.

Are minority-serving institutions specifically included as eligible applicants?

Yes. The FOA lists multiple mission-focused institutions and organizations as eligible, including HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and tribally controlled colleges and universities.

Are foreign institutions eligible to apply?

Yes. Foreign institutions are eligible to apply.

Are foreign components of U.S. organizations allowed?

Yes. Foreign components of U.S. organizations are allowed as defined by NIH policy.

Is cost sharing or matching required?

No. The FOA states there is no cost sharing or matching requirement.

What is the FOA number or identifier for this opportunity?

The opportunity is identified as PAR-11-315.

How is this grant opportunity categorized?

It is categorized as a discretionary grant program.

When was this FOA posted?

The FOA was posted on August 17, 2011.

What were the closing dates for this FOA?

The original closing date is listed as September 7, 2014, and the final listed closing date is November 21, 2014.

Is this FOA still open for applications?

No. The announcement was archived, with an archive date of December 21, 2014.

Where can the official NIH announcement be found?

The full announcement and official requirements were provided through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PAR-11-315.html.

Who should be contacted for access or technical issues with the online announcement?

For access or technical issues with the online announcement, the listed contact is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

Is this FOA intended to overlap with other standing NIH announcements?

The FOA explicitly states it is intended to expand the range of topics addressed with systems methods beyond what might be covered under other standing NIH announcements.

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