Opportunity Information: Apply for RFA 674 12 000002

  • The South Africa USAID Pretoria in the health sector is offering a public funding opportunity titled "Systems Strengthening for Better HIV/TB Patient Outcomes" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 98.001 USAID Foreign Assistance for Programs Overseas.
  • This funding opportunity was created on Jan 27, 2012 and posted on Dec 7, 2011.
  • Applicants must submit their applications by This is a two step RFA consisting of Step 1 Concept Paper Applications and Step 2 Full Application The dates for the two steps are indicated on the cover page of the RFA. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $425,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $150,000,000.00 in funding.
  • The number of recipients for this funding is limited to 8 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • Local South African non governmental organizations (NGO) and for profit organizations meeting the criteria in section III.
Apply for RFA 674 12 000002

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Opportunity Summary:

The grant opportunity titled "Systems Strengthening for Better HIV/TB Patient Outcomes" (Funding Opportunity Number RFA 674-12-000002) is a USAID South Africa (Pretoria) cooperative agreement program focused on reinforcing South African Government systems to improve health outcomes for people affected by HIV and TB, while also strengthening HIV prevention. The core emphasis is on comprehensive, clinic-based HIV-related services delivered across multiple levels of the health system, specifically hospitals, community health centers, and primary health care clinics. In practice, this kind of program is aimed at helping clinics function better as integrated service points so that patients are diagnosed earlier, linked to care faster, retained in treatment longer, and ultimately achieve better clinical outcomes, including reduced HIV transmission and improved TB-related outcomes.

The funding mechanism is a discretionary cooperative agreement, which typically means the funder expects substantial involvement during implementation, such as ongoing coordination, technical input, and performance oversight, rather than simply issuing a grant and stepping back. The activity category is health, and the opportunity is listed under CFDA 98.001 (USAID Foreign Assistance for Programs Overseas). The program anticipates making up to eight awards, indicating an intention to fund several implementers or consortia operating in different geographies, service delivery platforms, or technical areas, while still aligning to a common set of national system-strengthening goals.

Financially, the opportunity is large in scale. USAID listed an estimated total funding amount of $425,000,000, with individual award sizes ranging from a floor of $10,000,000 to a ceiling of $150,000,000. This suggests multi-year, large-coverage interventions that go beyond short-term service delivery and instead invest in sustained capacity, performance improvement, and system integration at facility and district levels. Cost sharing or matching is required, meaning applicants must contribute a portion of the total program cost through allowable forms of non-federal support, as defined in the solicitation, which can influence how organizations structure budgets, partnerships, and in-kind contributions.

Eligibility is targeted to local South African entities, specifically South African non-governmental organizations and for-profit organizations that meet the criteria laid out in Section III of the announcement. The notice references additional eligibility clarification in the "Additional Information on Eligibility" section, implying there may be specific registration, compliance, local presence, governance, or past-performance requirements that applicants must satisfy. By limiting eligibility to local organizations, the opportunity aligns with a local capacity and ownership approach, supporting South African institutions to lead and manage key components of the HIV/TB response.

The application process is structured as a two-step Request for Applications (RFA). Step 1 requires submission of a concept paper, and Step 2 requires a full application from selected applicants or those invited to proceed, depending on the RFA instructions. The posting notes that the specific dates for each step are provided on the cover page of the RFA rather than in the summary itself. This two-step format is often used to reduce the burden on applicants and the agency by screening for alignment and feasibility at the concept stage before requiring full technical and cost proposals.

From an implementation standpoint, the program description signals a focus on strengthening systems rather than only direct clinical service provision. "Systems strengthening" in this context commonly includes improving clinic workflows, data and monitoring systems, supply chain and commodity management, staffing models and training, quality improvement processes, patient tracking and referral systems, and integration of HIV and TB services so that patients receive coordinated care. It can also include improving governance and accountability mechanisms across facilities and districts, supporting adherence to national guidelines, and building the operational capacity of local partners to plan, implement, and sustain services. The explicit mention of comprehensive clinic-based HIV-related services across facility types implies work that spans the continuum of care and addresses gaps that often lead to loss to follow-up, delayed treatment initiation, and inconsistent TB screening and management among people living with HIV.

Key administrative details include the posted date of December 7, 2011, and a creation date of January 27, 2012. Questions or issues accessing the full announcement are directed to Beatrice Lumande, Acquisition Assistance Specialist at USAID South Africa, with contact via phone (+27 12 452 2377) or email (Applications4@usaid.gov). Overall, this opportunity represents a major USAID investment designed to help South Africa strengthen government-led service delivery systems in clinics and hospitals to achieve better HIV/TB patient outcomes and reinforce HIV prevention through stronger, more reliable, and better-integrated care.

Frequently Asked Questions (FAQs): Systems Strengthening for Better HIV/TB Patient Outcomes

What is the official title of this grant opportunity?

The opportunity is titled "Systems Strengthening for Better HIV/TB Patient Outcomes."

What is the Funding Opportunity Number (FON)?

The Funding Opportunity Number is RFA 674-12-000002.

Which USAID office is offering this opportunity?

This is a USAID South Africa (Pretoria) opportunity.

What type of funding instrument is being used?

The funding mechanism is a discretionary cooperative agreement.

What does "cooperative agreement" imply for implementation?

A cooperative agreement typically indicates substantial involvement by the funder during implementation, such as coordination, technical input, and performance oversight, rather than providing funding with minimal engagement.

What is the program trying to achieve?

The program focuses on reinforcing South African Government systems to improve health outcomes for people affected by HIV and TB, while also strengthening HIV prevention. A central goal is to help clinic-based services function better as integrated service points so patients are diagnosed earlier, linked to care faster, retained in treatment longer, and achieve improved clinical outcomes (including reduced HIV transmission and improved TB-related outcomes).

What is the primary technical focus of the activity?

The core emphasis is on comprehensive, clinic-based HIV-related services delivered across multiple levels of the health system, including hospitals, community health centers, and primary health care clinics.

Which activity category does this opportunity fall under?

The activity category is health.

What CFDA listing applies to this opportunity?

The opportunity is listed under CFDA 98.001 (USAID Foreign Assistance for Programs Overseas).

How many awards does USAID expect to make?

USAID anticipates making up to eight awards.

What is the estimated total funding available?

The estimated total funding amount is $425,000,000.

What is the expected range of award sizes?

Individual awards are expected to range from a minimum (floor) of $10,000,000 to a maximum (ceiling) of $150,000,000.

Does this opportunity require cost sharing or matching?

Yes. Cost sharing or matching is required, meaning applicants must contribute a portion of total program costs through allowable non-federal support as defined in the solicitation.

Who is eligible to apply?

Eligibility is limited to local South African entities: South African non-governmental organizations and South African for-profit organizations that meet the criteria described in Section III of the announcement.

Are there additional eligibility requirements beyond being a South African NGO or for-profit?

The notice references further details in an "Additional Information on Eligibility" section and in Section III, suggesting there may be additional criteria (such as registration, compliance, local presence, governance, or past-performance requirements) that applicants must meet as specified in the announcement.

Is this opportunity designed to support local ownership and capacity?

Yes. By limiting eligibility to local South African organizations, the opportunity aligns with a local capacity and ownership approach and supports South African institutions to lead and manage key components of the HIV/TB response.

What is the application format (one-step or multi-step)?

The application process is a two-step Request for Applications (RFA).

What is required in Step 1?

Step 1 requires submission of a concept paper.

What is required in Step 2?

Step 2 requires a full application from applicants selected or invited to proceed, depending on the RFA instructions.

Where can applicants find the due dates for Step 1 and Step 2?

The posting indicates the specific dates for each step are provided on the cover page of the RFA rather than in the summary.

What does "systems strengthening" mean in this program context?

In this context, systems strengthening commonly includes improvements to clinic workflows, data and monitoring systems, supply chain and commodity management, staffing models and training, quality improvement processes, patient tracking and referral systems, and integration of HIV and TB services so patients receive coordinated care.

Is the program focused only on direct service delivery?

No. The description signals a focus on strengthening systems rather than only providing direct clinical services.

Which levels of the health system are emphasized?

The opportunity emphasizes multiple levels of the health system: hospitals, community health centers, and primary health care clinics.

What kinds of patient outcomes is the program aiming to improve?

The program aims to improve outcomes such as earlier diagnosis, faster linkage to care, longer retention in treatment, better clinical outcomes, reduced HIV transmission, and improved TB-related outcomes.

Does the description mention integration of HIV and TB services?

Yes. It highlights integrating HIV and TB services so that patients receive coordinated care and gaps in screening, initiation, and management are reduced.

Why does the opportunity anticipate multiple awards?

Because up to eight awards are anticipated, USAID appears positioned to fund multiple implementers or consortia that may operate in different geographies, service delivery platforms, or technical areas while aligning to national system-strengthening goals.

When was this opportunity posted and when was it created?

Posted date: December 7, 2011. Creation date: January 27, 2012.

Who should be contacted for questions or for help accessing the full announcement?

Beatrice Lumande, Acquisition Assistance Specialist at USAID South Africa.

What contact details are provided for the point of contact?

Phone: +27 12 452 2377
Email: Applications4@usaid.gov

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