Opportunity Information: Apply for PAR 15 190
Apply for PAR 15 190
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "T1 Translational Research Novel Interventions for Prevention and Treatment of Age related Conditions (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866 Aging Research.
- This funding opportunity was created on Apr 28, 2015 and posted on Apr 28, 2015.
- Applicants must submit their applications by Sep 7, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Small businesses City or township governments County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Independent school districts State governments Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Private institutions of higher education Native American tribal governments (Federally recognized).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The funding opportunity titled "T1 Translational Research Novel Interventions for Prevention and Treatment of Age related Conditions (R21)" (Funding Opportunity Number PAR-15-190) is an NIH discretionary grant solicitation focused on early stage, exploratory, and developmental translational aging research. The central purpose is to speed up the development of new interventions that can prevent, treat, or otherwise address major health conditions that disproportionately affect older adults. The FOA is framed around "T1 translational research," meaning work that takes insights from basic biomedical research and/or clinical findings and pushes them toward practical therapeutic strategies, including the kinds of steps needed to move a concept closer to a viable intervention.
This announcement is specifically interested in novel therapeutics across a broad range of modalities. It explicitly includes biologics, pharmacological approaches, and non-pharmacological approaches, signaling that proposed projects do not need to be limited to traditional small-molecule drugs. The emphasis is on accelerating progress toward interventions for age-related pathologies and key health issues in the elderly, which typically implies projects that build a bridge between discovery and initial development, such as early proof-of-concept, feasibility testing, development of intervention candidates, or other translational activities that help de-risk and advance a potential prevention or treatment strategy. Because it uses the NIH R21 mechanism, it is geared toward exploratory work rather than large, definitive clinical trials or long-term, fully mature development programs.
Administratively, this is a grant (FundingInstrumentType: Grant) within the health category and is indexed under CFDA 93.866 (Aging Research). The opportunity indicated an estimated total funding level of $1,000,000 and listed an award ceiling of $200,000. Cost sharing or matching is not required, which is typical for many NIH research grants and reduces the burden on applicants to provide non-federal funds.
Eligibility is broad and spans many common U.S.-based research and public-serving entities. Eligible applicants include public and private institutions of higher education, public and state-controlled institutions of higher education, nonprofit organizations (including 501(c)(3) nonprofits and certain nonprofits without 501(c)(3) status), for-profit organizations (including small businesses and other for-profits), and a range of government entities such as state governments, county and city/township governments, independent school districts, special district governments, and public housing authorities/Indian housing authorities. Tribal entities are also included, both federally recognized Native American tribal governments and other tribal organizations, along with tribally controlled colleges and universities. The announcement also calls out categories often highlighted by NIH for inclusivity and capacity building, including HBCUs, Hispanic-serving institutions, AANAPISIs, Alaska Native and Native Hawaiian-serving institutions, and faith-based or community-based organizations, among others. A key limitation is that non-U.S. (foreign) institutions are not eligible to apply, and foreign components of U.S. organizations are not allowed, consistent with NIH rules restricting foreign involvement for this specific FOA.
In terms of timing, the FOA was posted and created on April 28, 2015, with a closing date of September 7, 2018, and an archive date of October 8, 2018, meaning it is no longer accepting applications under that specific announcement as written. The sponsoring agency is the National Institutes of Health. For applicants or readers needing the full original text, the FOA provided an NIH guide link (http://grants.nih.gov/grants/guide/pa-files/PAR-15-190.html) and directs technical access or linking issues to the NIH Office of Extramural Research webmaster contact (FBOWebmaster@OD.NIH.GOV).
FAQs: T1 Translational Research Novel Interventions for Prevention and Treatment of Age related Conditions (R21) - PAR-15-190
What is the official title and funding opportunity number for this grant?
The opportunity is titled "T1 Translational Research Novel Interventions for Prevention and Treatment of Age related Conditions (R21)" and the Funding Opportunity Number is PAR-15-190.
Which federal agency sponsors this funding opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
What type of award is this?
This opportunity is a Grant (FundingInstrumentType: Grant) using the NIH R21 mechanism.
What does the NIH R21 mechanism imply about the type of work expected?
Because this is an R21, it is geared toward early-stage, exploratory, and developmental research rather than large, definitive clinical trials or long-term, fully mature development programs.
What is the main purpose of this FOA?
The central purpose is to speed up the development of new interventions that can prevent, treat, or otherwise address major health conditions that disproportionately affect older adults, by advancing early translational work that moves concepts toward viable interventions.
What is meant by "T1 translational research" in this announcement?
In this FOA, "T1 translational research" refers to work that takes insights from basic biomedical research and/or clinical findings and pushes them toward practical therapeutic strategies, including steps that move a concept closer to a viable intervention.
What kinds of interventions are of interest under this FOA?
The announcement is interested in novel therapeutics across a broad range of modalities, explicitly including biologics, pharmacological approaches, and non-pharmacological approaches.
Do proposed projects have to focus on traditional drug development?
No. The FOA explicitly includes multiple modalities (including non-pharmacological approaches), so projects do not need to be limited to traditional small-molecule drugs.
What kinds of activities fit the early translational focus described in the FOA?
The FOA emphasizes activities that bridge discovery and initial development, such as early proof-of-concept work, feasibility testing, development of intervention candidates, or other translational activities that help de-risk and advance a prevention or treatment strategy.
What health area or category does this opportunity fall under?
This is a health-focused research opportunity centered on aging research and interventions for age-related conditions.
What CFDA number is associated with this opportunity?
The opportunity is indexed under CFDA 93.866 (Aging Research).
How much total funding was estimated for this opportunity?
The opportunity indicated an estimated total funding level of $1,000,000.
What is the award ceiling listed for this FOA?
The listed award ceiling is $200,000.
Is cost sharing or matching required?
No. Cost sharing or matching is not required.
Who is eligible to apply?
Eligibility is broad and includes public and private institutions of higher education (including public and state-controlled institutions), nonprofit organizations (including 501(c)(3) nonprofits and certain nonprofits without 501(c)(3) status), for-profit organizations (including small businesses and other for-profits), and various government entities (such as state, county, and city/township governments, independent school districts, special district governments, and public housing authorities/Indian housing authorities). Tribal entities are also included, such as federally recognized Native American tribal governments, other tribal organizations, and tribally controlled colleges and universities.
Are minority-serving institutions and community-based organizations included in the eligible organization types?
Yes. The FOA calls out categories often highlighted for inclusivity and capacity building, including HBCUs, Hispanic-serving institutions, AANAPISIs, Alaska Native and Native Hawaiian-serving institutions, and faith-based or community-based organizations, among others.
Are non-U.S. (foreign) institutions eligible to apply?
No. Non-U.S. (foreign) institutions are not eligible to apply under this FOA.
Are foreign components of U.S. organizations allowed?
No. Foreign components of U.S. organizations are not allowed, consistent with NIH rules restricting foreign involvement for this specific FOA.
When was this FOA posted and when did it close?
The FOA was posted and created on April 28, 2015. The closing date was September 7, 2018.
Is this funding opportunity still accepting applications?
No. The FOA lists a closing date of September 7, 2018 and an archive date of October 8, 2018, which indicates it is no longer accepting applications under that specific announcement as written.
Where can applicants find the full original FOA text?
The FOA directs readers to the NIH Guide page at http://grants.nih.gov/grants/guide/pa-files/PAR-15-190.html.
Who should be contacted for technical access or linking issues related to the FOA?
The FOA directs technical access or linking issues to the NIH Office of Extramural Research webmaster contact at FBOWebmaster@OD.NIH.GOV.
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