Opportunity Information: Apply for RFA AG 12 009

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "T1 Translational Research on Aging Small Business Innovation Awards (R43/R44)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866 Aging Research.
  • This funding opportunity was created on Aug 4, 2011 and posted on Aug 4, 2011.
  • Applicants must submit their applications by Nov 4, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
  • Eligible applicants include: Small businesses.
Apply for RFA AG 12 009

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Opportunity Summary:

The grant opportunity titled "T1 Translational Research on Aging Small Business Innovation Awards (R43/R44)" (Funding Opportunity Number RFA-AG-12-009) is a discretionary National Institutes of Health (NIH) funding program designed to move aging-related scientific discoveries closer to real-world use. Its central purpose is to accelerate translation, meaning it supports work that takes promising research findings and turns them into practical, scalable solutions that can be developed, validated, and ultimately commercialized to help older adults maintain health, function, and independence. The program is aimed at strengthening the role of small businesses as engines of innovation, since companies are often positioned to package research into products and services that can actually reach clinics, communities, caregivers, and consumers.

This funding announcement supports Small Business Innovation Research (SBIR) grants using the R43 and R44 mechanisms, which generally correspond to phased development. In practice, this structure is commonly used to help a small business move from early feasibility and proof-of-concept activities toward more advanced research and development steps that position an innovation for commercialization. The FOA explicitly emphasizes innovations that have both a strong likelihood of benefiting older adults and a realistic path to commercial success, meaning applicants are expected to think beyond basic science and demonstrate a credible plan for development, adoption, and market impact. The types of innovations envisioned are broad and can include novel devices, products, healthcare practices, and programs, as long as they are meaningfully connected to aging and have translational potential.

The activity area is health, with the CFDA listing under 93.866 (Aging Research). Eligibility is limited to small businesses, reinforcing the program's intent to mobilize private-sector capabilities in product development, regulatory planning where relevant, manufacturing considerations, usability testing, implementation strategies, and go-to-market preparation. The announcement also indicates there is no cost-sharing or matching requirement, which lowers barriers for early-stage companies that may not have extensive capital.

From an administrative standpoint, the opportunity was posted and created on August 4, 2011, with an original and current closing date of November 4, 2011, and it was archived on December 5, 2011. The estimated total funding amount listed for the program is $2,000,000. The sponsoring agency is the National Institutes of Health, and the full announcement was made available through the NIH grants guide at http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-12-009.html. For access or technical issues related to the online announcement, the contact provided is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV, including support for difficulties accessing the FOA electronically or problems linking to the announcement.

Overall, this FOA is best understood as a targeted SBIR initiative in translational aging research: it is not primarily about generating new basic knowledge, but about supporting small businesses in building and testing innovations that can realistically be brought to market and used to improve health outcomes and functional independence for older adults.

Frequently Asked Questions (FAQs)

What is the official title of this grant opportunity?

The official title is "T1 Translational Research on Aging Small Business Innovation Awards (R43/R44)."

What is the Funding Opportunity Number (FOA number)?

The Funding Opportunity Number is RFA-AG-12-009.

Which federal agency is sponsoring this funding opportunity?

The sponsoring agency is the National Institutes of Health (NIH).

What is the main purpose of this SBIR funding opportunity?

The central purpose is to accelerate translation in aging research by helping small businesses move promising aging-related scientific discoveries closer to real-world use. The focus is on developing practical, scalable solutions that can be developed, validated, and ultimately commercialized to help older adults maintain health, function, and independence.

Is this opportunity focused on basic science or on translational development?

This opportunity is described as a targeted SBIR initiative in translational aging research. It is not primarily aimed at generating new basic knowledge; it is intended to support development and testing of innovations that can realistically be brought to market and used to improve outcomes for older adults.

What grant mechanisms does this program use?

This announcement supports Small Business Innovation Research (SBIR) grants using the R43 and R44 mechanisms.

How should applicants think about the R43 and R44 structure?

The R43/R44 structure generally corresponds to phased development. It is commonly used to help a small business move from early feasibility and proof-of-concept activities toward more advanced research and development steps that position an innovation for commercialization.

Who is eligible to apply?

Eligibility is limited to small businesses.

Why does the FOA limit eligibility to small businesses?

The opportunity is designed to strengthen the role of small businesses as engines of innovation, since companies are often positioned to package research into products and services that can reach clinics, communities, caregivers, and consumers.

What topic area or discipline does this opportunity fall under?

The activity area is health, with the CFDA listing under 93.866 (Aging Research).

What kinds of projects or innovations does the FOA encourage?

The FOA envisions a broad range of aging-related innovations with translational potential, including novel devices, products, healthcare practices, and programs, as long as they are meaningfully connected to aging and aimed at real-world use.

What outcomes or impacts is this funding trying to support for older adults?

The program emphasizes innovations that can help older adults maintain health, function, and independence, with the expectation that successful projects move toward real-world adoption and use.

Does the FOA emphasize commercialization?

Yes. The announcement explicitly emphasizes innovations that have both a strong likelihood of benefiting older adults and a realistic path to commercial success. Applicants are expected to think beyond basic science and present a credible plan for development, adoption, and market impact.

What kinds of development considerations are relevant under this FOA?

The opportunity is intended to mobilize private-sector capabilities tied to product development, including areas such as regulatory planning (where relevant), manufacturing considerations, usability testing, implementation strategies, and go-to-market preparation.

Is cost-sharing or matching required?

No. The announcement indicates there is no cost-sharing or matching requirement.

What is the estimated total funding amount listed for the program?

The estimated total funding amount listed is $2,000,000.

When was this opportunity posted and created?

It was posted and created on August 4, 2011.

What was the closing date for this funding opportunity?

The original and current closing date listed is November 4, 2011.

Is this FOA still active?

No. The opportunity was archived on December 5, 2011.

Where can applicants find the full announcement text?

The full announcement was made available through the NIH grants guide at http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-12-009.html.

Who should be contacted for technical problems accessing the announcement online?

For access or technical issues related to the online announcement (such as difficulty accessing the FOA electronically or problems linking to the announcement), the contact provided is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

What does "T1 translational research" mean in the context provided?

In the context provided, "T1 translational research" refers to work that takes promising aging-related research findings and advances them toward practical, scalable solutions that can be developed, validated, and moved toward commercialization for real-world use.

What types of end users are implied for the innovations supported by this FOA?

The opportunity describes innovations that can ultimately reach real-world settings and users, including clinics, communities, caregivers, and consumers.

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Previous opportunity: T2 Translational Research on Aging Small Business Innovation Awards (R43/R44)

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