Opportunity Information: Apply for PA 09 188

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Technologies and Software to Support Integrative Cancer Biology Research (SBIR) R43/R44" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.396 Cancer Biology Research.
  • This funding opportunity was created on May 19, 2009 and posted on May 19, 2009.
  • Applicants must submit their applications by May 7, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: Small businesses.
Apply for PA 09 188

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Opportunity Summary:

The funding opportunity titled "Technologies and Software to Support Integrative Cancer Biology Research (SBIR) R43/R44" (Funding Opportunity Number PA-09-188) is a National Cancer Institute (NCI) announcement under the National Institutes of Health that aims to stimulate small businesses to build commercially oriented tools that make integrative cancer biology research easier, faster, and more powerful. The central idea behind integrative cancer biology is that cancer should be studied as a complex system rather than as isolated parts. That means combining computational approaches with experimental biology, pulling together many different kinds of data (for example, molecular, cellular, imaging, clinical, or other high-dimensional datasets), and using that integrated picture to create predictive computational models that explain or forecast cancer-related processes.

This FOA specifically invites Small Business Innovation Research (SBIR) applications from eligible small business concerns proposing new or improved software tools, computational and mathematical methods, and enabling technologies that support this kind of integrative work. In practice, the solicitation is geared toward products that researchers can actually use and that have a path toward commercialization, rather than one-off academic code or purely exploratory methods without a clear deliverable. The types of efforts that fit the spirit of the announcement include platforms for integrating heterogeneous cancer datasets, modeling and simulation tools, analysis pipelines, algorithmic methods that connect experimental and computational data streams, and other technologies that help teams build and validate predictive models of cancer biology.

The mechanism of support is the SBIR program using the R43/R44 grant structures, which cover Phase I, Phase II, and Fast Track applications. Phase I typically supports early feasibility and proof-of-concept work, Phase II supports full research and development and product maturation, and Fast Track is designed to move applicants more quickly from Phase I to Phase II through a combined application. The announcement also notes related SBIR opportunities that use the same mechanism (PA-09-187 and PA-09-189), which can be useful context for applicants trying to confirm fit across similar NIH solicitations.

On funding and award expectations, the FOA emphasizes that awards depend on the availability of funds and on receiving enough high-quality, meritorious applications. There is no guaranteed number of awards; both the total dollars awarded and the number of funded projects are variable and will be driven by application quality, proposed project period, and requested budgets. The listed award ceiling is $200,000, and the opportunity indicates there is no cost sharing or matching requirement, which is typical for many NIH SBIR grants.

Administrative details in the source record show the opportunity is categorized as discretionary funding and uses the grant funding instrument type, with an activity category connected to health and cancer biology research (CFDA 93.396). Eligibility is limited to small businesses. The opportunity was posted and created on May 19, 2009, and it had an original and current closing date of May 7, 2012, with an archive date of June 7, 2012, meaning it is no longer open for new submissions under that specific announcement. The full announcement was hosted through the NIH grants guide at the provided link, and technical help for accessing or linking to the announcement was routed through the NIH Office of Extramural Research (OER) webmaster contact.

Frequently Asked Questions (FAQs)

What is the title and funding opportunity number for this grant?

The opportunity is titled "Technologies and Software to Support Integrative Cancer Biology Research (SBIR) R43/R44" and the Funding Opportunity Number is PA-09-188.

Which agency and institute are sponsoring this opportunity?

This is a National Cancer Institute (NCI) announcement under the National Institutes of Health (NIH).

What is the main purpose of this funding opportunity?

The goal is to stimulate small businesses to build commercially oriented tools that make integrative cancer biology research easier, faster, and more powerful.

What does "integrative cancer biology" mean in the context of this FOA?

Integrative cancer biology treats cancer as a complex system rather than a collection of isolated parts. It emphasizes combining computational approaches with experimental biology and integrating many different types of data to create predictive computational models that explain or forecast cancer-related processes.

What types of projects does the FOA invite?

The FOA invites SBIR applications proposing new or improved software tools, computational and mathematical methods, and enabling technologies that support integrative cancer biology research.

What kinds of tools or technologies are considered a good fit?

Examples aligned with the announcement include platforms for integrating heterogeneous cancer datasets, modeling and simulation tools, analysis pipelines, algorithmic methods that connect experimental and computational data streams, and other technologies that help teams build and validate predictive models of cancer biology.

What is meant by "commercially oriented" tools?

The solicitation is geared toward products that researchers can actually use and that have a path toward commercialization, rather than one-off academic code or purely exploratory methods without a clear deliverable.

What data types are mentioned as relevant for integration?

The FOA references integrating many kinds of data, such as molecular, cellular, imaging, clinical, or other high-dimensional datasets.

What funding mechanism is used for this opportunity?

This opportunity uses the Small Business Innovation Research (SBIR) program under the NIH R43/R44 grant structures.

Which project phases are supported under R43/R44?

The R43/R44 mechanism covers Phase I, Phase II, and Fast Track applications.

What is Phase I intended to support?

Phase I typically supports early feasibility and proof-of-concept work.

What is Phase II intended to support?

Phase II supports full research and development and product maturation.

What is a Fast Track application in this context?

Fast Track is designed to move applicants more quickly from Phase I to Phase II through a combined application.

Who is eligible to apply?

Eligibility is limited to small businesses (eligible small business concerns) applying through the SBIR program.

Is cost sharing or matching required?

No. The opportunity indicates there is no cost sharing or matching requirement.

What is the listed award ceiling?

The listed award ceiling is $200,000.

How many awards will be made?

There is no guaranteed number of awards. The FOA states that both the number of funded projects and total dollars awarded are variable and depend on the availability of funds and the receipt of sufficiently high-quality, meritorious applications.

What factors influence whether an award is made?

The FOA notes that awards depend on the availability of funds and on receiving enough high-quality, meritorious applications. It also indicates that outcomes vary based on application quality, proposed project period, and requested budgets.

What type of funding opportunity is this categorized as?

The source record categorizes this as discretionary funding and uses the grant funding instrument type.

Is there a CFDA number associated with this opportunity?

Yes. The activity category is connected to health and cancer biology research under CFDA 93.396.

When was this opportunity posted?

The opportunity was posted and created on May 19, 2009.

What were the closing and archive dates?

The original and current closing date was May 7, 2012, and the archive date was June 7, 2012.

Is this funding opportunity still open for new submissions?

No. Based on the closing and archive dates provided, this specific announcement is no longer open for new submissions.

Are there related SBIR opportunities mentioned?

Yes. The announcement notes related SBIR opportunities that use the same mechanism: PA-09-187 and PA-09-189.

Where was the full announcement hosted?

The full announcement was hosted through the NIH Grants Guide at the provided link in the source record.

Who is listed for technical help related to accessing or linking to the announcement?

Technical help for accessing or linking to the announcement was routed through the NIH Office of Extramural Research (OER) webmaster contact.

Browse more opportunities from the same agency: National Institutes of Health

Browse more opportunities from the same category: Education Health

Next opportunity: Technology Development for the Detection and Evaluation of Chemical and Biological Carcinogens (SBIR) R43/R44

Previous opportunity: Collaborative Minority Alcohol Research Center Development (U54)

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Technology Development for the Detection and Evaluation of Chemical and Biological Carcinogens (SBIR) R43/R44 Apply for PA 09 187

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Technology for the Detection and Characterization of Low Abundance Proteins, Peptides, or micro RNAs (SBIR) R43/R44 Apply for PA 09 189

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Integrating Translational Neuroscience and Adolescent Drug Abuse Treatment (R21) Apply for RFA DA 10 003

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International Research Collaborations on HIV/AIDS and Drug Use (R01) Apply for RFA DA 10 008

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Centers of Cancer Nanotechnology Excellence (CCNEs)(U54) Apply for RFA CA 09 012

Funding Number: RFA CA 09 012
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Funding Number: RFA CA 09 013
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Funding Number: PA 09 197
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Biomarkers for Early Detection of Hematopoietic Malignancies (R21) Apply for PA 09 198

Funding Number: PA 09 198
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Identifying Non coding RNA Targets for Cancer Early Detection and Prevention (R21) Apply for PA 09 200

Funding Number: PA 09 200
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Identifying Non coding RNA Targets for Cancer Early Detection and Prevention (R01) Apply for PA 09 199

Funding Number: PA 09 199
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The National Drug Abuse Treatment Clinical Trials Network (U10) Apply for RFA DA 10 009

Funding Number: RFA DA 10 009
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Bioenergetics, Fatigability, and Activity Limitations in Aging (R21) Apply for PA 09 191

Funding Number: PA 09 191
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Bioenergetics, Fatigability, and Activity Limitations in Aging (R01) Apply for PA 09 190

Funding Number: PA 09 190
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Exploratory Grant Award to Promote Workforce Diversity in Basic Cancer Research (R21) Apply for PAR 09 162

Funding Number: PAR 09 162
Agency: National Institutes of Health
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Feasibility Studies for Collaborative Interaction for Minority Institution/Cancer Center Partnership (P20) Apply for PAR 09 201

Funding Number: PAR 09 201
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Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellows (F31) Apply for PA 09 208

Funding Number: PA 09 208
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Cutting Edge Basic Research Awards (CEBRA) (R21) Apply for PAR 09 222

Funding Number: PAR 09 222
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Cancer Intervention and Surveillance Modeling Network (CISNET) (U01) Apply for RFA CA 09 025

Funding Number: RFA CA 09 025
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The Early Detection Research Network Biomarker Developmental Laboratories (U01) Apply for RFA CA 09 017

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Funding Number: PAR 09 227
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