Opportunity Information: Apply for RFA HG 14 025
Apply for RFA HG 14 025
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "The Electronic Medical Records and Genomics (eMERGE) Network, Phase III Study Investigators (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172 Human Genome Research.
- This funding opportunity was created on Jul 9, 2014 and posted on Jul 9, 2014.
- Applicants must submit their applications by Nov 12, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $9,900,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $600,000.00 in funding.
- Eligible applicants include: County governments Public and State controlled institutions of higher education Private institutions of higher education Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Native American tribal governments (Federally recognized) For profit organizations other than small businesses Independent school districts Special district governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Foreign Institutions Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The funding opportunity titled "The Electronic Medical Records and Genomics (eMERGE) Network, Phase III Study Investigators (U01)" (Funding Opportunity Number RFA HG 14 025) is a National Institutes of Health (NIH) cooperative agreement intended to support the next phase of work in the eMERGE Network. The central goal of this announcement is to keep advancing genomic discovery and real-world implementation research by funding study investigators who already have the core infrastructure needed to contribute quickly and meaningfully: established biorepositories that are linked to electronic medical records (EMRs), along with existing genome-wide genotyping and/or sequencing datasets. In other words, the FOA is designed to build on prior investments and accelerate research that connects genomic variation to clinical phenotypes captured in health records, while also pushing toward practical clinical use of genomic information within healthcare systems.
As a Phase III effort, the opportunity emphasizes continuation and expansion rather than starting from scratch. Applicants are expected to be positioned to leverage EMR-linked biospecimen collections and large-scale genomic data to support network-style science, where multiple sites contribute data, methods, and findings that can be combined across the consortium. The use of the U01 cooperative agreement mechanism signals that NIH anticipates substantial scientific and programmatic involvement during the award period. Compared with a typical investigator-initiated grant, a cooperative agreement generally means the project will be carried out in close coordination with NIH and other network participants, aligning protocols, data standards, and collaborative deliverables so that the network functions as an integrated whole.
This FOA falls under the health activity category and is associated with CFDA number 93.172 (Human Genome Research). The announcement states there is no cost sharing or matching requirement. The total estimated funding amount is listed as $9,900,000, and the award ceiling is $600,000, indicating the approximate maximum amount available per award under this announcement (with actual award sizes dependent on NIH priorities, the number of awards made, and the scope of proposed work).
Eligibility is broad and includes many types of U.S.-based organizations. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, state governments, county governments, city or township governments, special district governments, and independent school districts. Nonprofit organizations are eligible, including 501(c)(3) nonprofits and certain nonprofits without 501(c)(3) status (other than institutions of higher education). Tribal entities are included both as federally recognized tribal governments and other Native American tribal organizations, and tribally controlled colleges and universities are also explicitly referenced. The FOA also allows small businesses and for-profit organizations (other than small businesses) to apply, and it includes public housing authorities and Indian housing authorities. Additional eligible applicant categories mentioned include Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and Asian American, Native American, and Pacific Islander-serving institutions (AANAPISIs), along with faith-based or community-based organizations, regional organizations, and eligible federal agencies.
At the same time, the eligibility section draws clear boundaries around foreign participation. Foreign institutions and other non-U.S. entities are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed. This means the work and applicant organization are expected to be domestic in the sense required by NIH rules for this specific FOA.
From an administrative timeline standpoint, the FOA was posted and created on July 9, 2014, with an original and current closing date of November 12, 2014, and an archive date of December 13, 2014. While those dates indicate the opportunity is historical rather than currently open, the description still captures what NIH sought to fund at that time: established, EMR-linked genomic resources integrated into a collaborative network aimed at discovering genotype-phenotype relationships and testing how genomic findings can be implemented in clinical care settings.
For those looking for the full original announcement text and any detailed requirements (such as specific aims, data sharing expectations, network governance, milestones, and required collaboration structures), the FOA points to the NIH grants guide page at http://grants.nih.gov/grants/guide/rfa files/RFA HG 14 025.html. The contact information provided is for the NIH Office of Extramural Research (OER) webmaster (FBOWebmaster@OD.NIH.GOV) for technical issues accessing or linking to the announcement.
Frequently Asked Questions (FAQs)
What is the name of this funding opportunity?
The opportunity is titled "The Electronic Medical Records and Genomics (eMERGE) Network, Phase III Study Investigators (U01)."
What is the Funding Opportunity Number (FOA number)?
The Funding Opportunity Number is RFA HG 14 025.
Who is offering this grant opportunity?
This is a National Institutes of Health (NIH) funding opportunity, using a cooperative agreement mechanism.
What is the overall purpose of this FOA?
The central goal is to advance genomic discovery and real-world implementation research by supporting study investigators who already have the core infrastructure to contribute quickly, including established biorepositories linked to electronic medical records (EMRs) and existing genome-wide genotyping and/or sequencing datasets.
What types of projects is NIH trying to accelerate through this program?
The program is designed to build on prior investments and speed up research that connects genomic variation to clinical phenotypes captured in health records, while also pushing toward practical clinical use of genomic information within healthcare systems.
What does "Phase III" mean in the context of this eMERGE Network opportunity?
Phase III emphasizes continuation and expansion of existing capabilities rather than starting from scratch. Applicants are expected to be positioned to leverage existing EMR-linked biospecimen collections and large-scale genomic data in a networked, consortium-style setting.
What is the required infrastructure or readiness expected of applicants?
Applicants are expected to already have established biorepositories linked to EMRs and to have existing genome-wide genotyping and/or sequencing datasets so they can contribute quickly and meaningfully to the network.
What is meant by "network-style science" in this FOA?
It refers to a consortium approach where multiple sites contribute data, methods, and findings that can be combined across the network, enabling coordinated research across participating institutions.
What grant mechanism is being used?
The mechanism is U01, which is a cooperative agreement.
How is a U01 cooperative agreement different from a typical research grant?
A cooperative agreement generally involves substantial scientific and programmatic involvement by NIH during the award period. Projects are expected to be carried out in close coordination with NIH and other network participants, aligning protocols, data standards, and collaborative deliverables so the network operates as an integrated whole.
What is the CFDA number associated with this opportunity?
The CFDA number listed is 93.172 (Human Genome Research).
What is the health activity category for this opportunity?
The FOA is identified under the health activity category.
Is cost sharing or matching required?
No. The announcement states there is no cost sharing or matching requirement.
What is the total estimated funding amount for this FOA?
The total estimated funding amount is listed as $9,900,000.
What is the award ceiling?
The award ceiling is listed as $600,000, describing the approximate maximum amount available per award under this announcement.
Does the award ceiling guarantee each award will be $600,000?
No. The FOA indicates actual award sizes depend on NIH priorities, the number of awards made, and the scope of the proposed work.
What types of organizations are eligible to apply?
Eligibility is broad and includes many U.S.-based organizations, such as public and state-controlled institutions of higher education, private institutions of higher education, state governments, county governments, city or township governments, special district governments, independent school districts, and nonprofit organizations (including 501(c)(3) nonprofits and certain nonprofits without 501(c)(3) status, other than institutions of higher education).
Are tribal entities eligible?
Yes. The eligibility list includes federally recognized tribal governments, other Native American tribal organizations, and tribally controlled colleges and universities.
Can small businesses apply?
Yes. Small businesses are included among eligible applicants.
Can for-profit organizations apply?
Yes. For-profit organizations (other than small businesses) are listed as eligible.
Are public housing authorities eligible?
Yes. Public housing authorities and Indian housing authorities are included as eligible applicants.
Are minority-serving institutions specifically mentioned as eligible?
Yes. The FOA references categories including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and Asian American, Native American, and Pacific Islander-serving institutions (AANAPISIs).
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are explicitly mentioned among eligible applicant categories.
Are regional organizations eligible?
Yes. Regional organizations are included in the eligibility categories described.
Are federal agencies eligible to apply?
Yes. Eligible federal agencies are mentioned among the eligible applicant categories.
Are foreign institutions eligible to apply?
No. Foreign institutions and other non-U.S. entities are not eligible to apply under this FOA.
Are non-U.S. components of U.S. organizations allowed?
No. The FOA states that non-U.S. components of U.S. organizations are not eligible.
Are foreign components allowed in any form?
No. The eligibility section indicates that foreign components (as defined by NIH policy) are not allowed.
When was this FOA posted?
The FOA was posted (and created) on July 9, 2014.
What was the closing date for applications?
The original and current closing date listed is November 12, 2014.
When was the opportunity archived?
The archive date is December 13, 2014.
Is this funding opportunity currently open?
Based on the closing date (November 12, 2014) and the archive date (December 13, 2014), this appears to be a historical opportunity rather than one that is currently open.
Where can applicants find the full original FOA text?
The FOA points to the NIH grants guide page at http://grants.nih.gov/grants/guide/rfa files/RFA HG 14 025.html.
Who should be contacted for technical issues accessing or linking to the FOA?
The contact listed for technical issues is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
What kinds of detailed requirements might be found in the full FOA text?
The description indicates the full announcement may include detailed requirements such as specific aims, data sharing expectations, network governance, milestones, and required collaboration structures.
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