Opportunity Information: Apply for RFA GM 15 005
Apply for RFA GM 15 005
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "The NIGMS Human Genetic Cell Repository (U42)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.859 Biomedical Research and Research Training.
- This funding opportunity was created on Jul 31, 2014 and posted on Jul 31, 2014.
- Applicants must submit their applications by Oct 1, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,800,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $2,800,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Public housing authorities/Indian housing authorities For profit organizations other than small businesses Independent school districts Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments Native American tribal governments (Federally recognized) State governments Public and State controlled institutions of higher education Small businesses County governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The grant opportunity titled "The NIGMS Human Genetic Cell Repository (U42)" (Funding Opportunity Number RFA-GM-15-005) is a National Institutes of Health (NIH) discretionary funding announcement in the health category that uses a cooperative agreement mechanism. Its central goal is to support the ongoing operation and continued development of the NIGMS Human Genetic Cell Repository, a shared national resource intended to serve the broader biomedical research community. Under this award, the supported repository is expected to function as a reliable, high-quality infrastructure for preserving and expanding human genetic research materials and making them accessible to qualified investigators.
At the core of the program is the expectation that the repository will maintain an existing collection of cell cultures and DNA samples while also actively strengthening that collection over time. This involves acquiring new human cell samples, carefully characterizing them to ensure identity and quality, expanding them to produce sufficient quantities for research use, and distributing both cell lines and DNA isolated from those cell lines. In practical terms, the award is aimed at sustaining a pipeline that takes valuable human genetic specimens from acquisition through quality control and scale-up, then delivers well-documented, standardized biological materials to researchers who need consistent and dependable resources for experiments, replication studies, and broader scientific discovery.
The funding instrument is a U42 cooperative agreement, which generally indicates that NIH anticipates substantial programmatic involvement compared with a standard grant. The announcement lists an expected number of awards of one, meaning NIH intended to fund a single entity to run this national repository function for the project period covered by the solicitation. The estimated total funding is $2,800,000, and the award ceiling is also $2,800,000, indicating the anticipated maximum size of the single award under this opportunity. Cost sharing or matching is not required, so applicants were not expected to contribute non-federal matching funds as a condition of receiving the award.
Eligibility is broad across many organization types, reflecting the infrastructure-focused nature of a repository and the range of institutions capable of operating one. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits with or without 501(c)(3) status (including those other than institutions of higher education), for-profit organizations other than small businesses, small businesses, state governments, county governments, city or township governments, special district governments, and a variety of tribal entities (including federally recognized tribal governments and other tribal organizations). The announcement also notes eligibility for a range of mission-driven institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations where appropriate. It also references eligible federal agencies and U.S. territories or possessions. However, it explicitly excludes non-U.S. entities from applying: non-domestic (non-U.S.) organizations and institutions are not eligible, non-domestic components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed.
From an administrative perspective, the opportunity was posted on July 31, 2014, with an original and current closing date of October 1, 2014, and an archive date of November 1, 2014, meaning the solicitation is no longer active. The CFDA number associated with the program is 93.859 (Biomedical Research and Research Training). NIH is the issuing agency, and the full announcement was made available through the NIH Grants Guide at the link provided in the source. For access or technical issues related to the electronic announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Overall, this FOA was designed to ensure the continuity and high performance of a nationally important biomedical resource: a centralized, quality-controlled repository that preserves human genetic cell cultures and DNA, improves and expands those holdings over time, and distributes the resulting research-grade materials to qualified scientists to support reproducible, scalable biomedical research.
FAQs: The NIGMS Human Genetic Cell Repository (U42) - RFA-GM-15-005
What is the title and funding opportunity number for this grant?
The opportunity is titled "The NIGMS Human Genetic Cell Repository (U42)" and the Funding Opportunity Number (FON) is RFA-GM-15-005.
Which agency issued this funding opportunity?
The issuing agency is the National Institutes of Health (NIH).
What category does this opportunity fall under?
This is a discretionary funding announcement in the health category.
What is the main purpose of this funding opportunity?
The central goal is to support the ongoing operation and continued development of the NIGMS Human Genetic Cell Repository, a shared national resource meant to serve the broader biomedical research community.
What is the NIGMS Human Genetic Cell Repository expected to provide to the research community?
The repository is expected to operate as reliable, high-quality infrastructure that preserves and expands human genetic research materials and makes them accessible to qualified investigators.
What types of biological materials are involved in this program?
The program focuses on human cell cultures and DNA samples. The repository is expected to distribute both cell lines and DNA isolated from those cell lines.
What are the core activities the funded repository is expected to perform?
Core expectations include maintaining an existing collection of cell cultures and DNA samples and strengthening the collection over time by acquiring new human cell samples, characterizing them for identity and quality, expanding them to produce sufficient quantities for research use, and distributing cell lines and derived DNA to qualified researchers.
Does this opportunity emphasize quality control and standardization?
Yes. The description highlights careful characterization to ensure identity and quality, and it emphasizes distributing well-documented, standardized biological materials so researchers can use consistent and dependable resources.
What funding mechanism is used for this award?
The funding instrument is a U42 cooperative agreement.
What does a U42 cooperative agreement imply about NIH involvement?
A cooperative agreement generally indicates NIH expects substantial programmatic involvement compared with a standard grant.
How many awards were expected under this solicitation?
The announcement listed an expected number of awards of one, meaning NIH intended to fund a single entity to carry out this national repository function for the project period covered by the solicitation.
What was the estimated total funding and the award ceiling?
The estimated total funding was $2,800,000, and the award ceiling was also $2,800,000, indicating the anticipated maximum size of the single award under this opportunity.
Was cost sharing or matching required?
No. Cost sharing or matching was not required for applicants under this opportunity.
What types of organizations were eligible to apply?
Eligibility was broad and included: public and state-controlled institutions of higher education; private institutions of higher education; nonprofits (with or without 501(c)(3) status, including those other than institutions of higher education); for-profit organizations other than small businesses; small businesses; state governments; county governments; city or township governments; special district governments; tribal entities (including federally recognized tribal governments and other tribal organizations); eligible federal agencies; and U.S. territories or possessions.
Were mission-driven and minority-serving institutions included in the eligibility list?
Yes. The announcement referenced eligibility for institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs). It also noted faith-based or community-based organizations where appropriate.
Are non-U.S. (foreign) organizations eligible to apply?
No. The opportunity explicitly excluded non-U.S. entities: non-domestic (non-U.S.) organizations and institutions were not eligible, non-domestic components of U.S. organizations were not eligible, and foreign components (as defined by NIH policy) were not allowed.
What were the key dates for this funding opportunity?
The opportunity was posted on July 31, 2014. The original and current closing date was October 1, 2014. The archive date was November 1, 2014.
Is this funding opportunity still open?
No. Because the closing date was October 1, 2014 and the archive date was November 1, 2014, this solicitation is no longer active.
What CFDA number is associated with this program?
The CFDA number associated with the program is 93.859 (Biomedical Research and Research Training).
Where was the full announcement made available?
The full announcement was made available through the NIH Grants Guide (via the link provided in the source information for this opportunity).
Who is listed as the contact for access or technical issues related to the electronic announcement?
The listed contact is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Who is the repository intended to serve?
The repository is intended to serve the broader biomedical research community by making human genetic research materials available to qualified investigators.
What problem is this funding opportunity trying to solve or address?
It was designed to ensure continuity and high performance of a nationally important biomedical resource: a centralized, quality-controlled repository that preserves human genetic cell cultures and DNA, expands those holdings over time, and distributes research-grade materials to support reproducible, scalable biomedical research.
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