Opportunity Information: Apply for RFA HL 13 025
Apply for RFA HL 13 025
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Trans Agency Research Consortium for Trauma Induced Coagulopathy (TACTIC) (UM1)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.839 Blood Diseases and Resources Research.
- This funding opportunity was created on Nov 21, 2012 and posted on Nov 21, 2012.
- Applicants must submit their applications by Feb 6, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $24,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $4,800,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: City or township governments State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Native American tribal governments (Federally recognized) Special district governments Public and State controlled institutions of higher education Independent school districts County governments For profit organizations other than small businesses Small businesses.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The Trans Agency Research Consortium for Trauma Induced Coagulopathy (TACTIC) (UM1) is a NIH funding opportunity designed to build one coordinated, multi-component basic research program focused on trauma induced coagulopathy (TIC). TIC is a serious bleeding and clotting disorder that can develop after major trauma and is a major contributor to preventable death in both civilian and military settings. This opportunity is set up as a cooperative agreement (UM1), meaning the funded team would not simply receive support and operate independently; instead, the work would be carried out in close collaboration with the sponsoring agencies, with substantial scientific and programmatic involvement from the government partners.
A defining feature of TACTIC is its trans-agency structure and its intended “bench-to-bedside†linkage between ongoing trauma trials and mechanistic laboratory science. The National Heart, Lung and Blood Institute (NHLBI) and the Department of Defense (DoD) jointly support the effort, with the goal of forming a consortium that connects clinical investigators already conducting DoD-funded trauma-related clinical trials to basic scientists funded under the UM1 research program. In practical terms, the UM1 program is meant to take advantage of real-world, well-characterized patient samples collected through those ongoing clinical studies, allowing researchers to test hypothesis-driven questions about why TIC develops, how it evolves over time, and which biological pathways might be targeted to improve outcomes. The emphasis on “hypothesis-driven studies†signals that the program is looking for mechanistic and experimentally rigorous projects rather than purely descriptive studies.
From an administrative and funding standpoint, this was a discretionary grant opportunity issued by the National Institutes of Health under Funding Opportunity Number RFA-HL-13-025, categorized under health and tied to CFDA 93.839 (Blood Diseases and Resources Research). The program anticipated making a single award, reinforcing that this was intended to be one unified consortium rather than multiple independent projects. The estimated total funding level was $24,000,000, with an award ceiling of $4,800,000, and there was no cost sharing or matching requirement. The announcement was posted on November 21, 2012, with an application due date of February 6, 2013, and it was later archived on March 9, 2013.
Eligibility was broad across U.S.-based organizations, including state, county, city, township, special district, and certain tribal governments; public and private institutions of higher education; independent school districts; public housing authorities/Indian housing authorities; nonprofits with and without 501(c)(3) status; and for-profit organizations (including small businesses, though not “other than small businesses†restrictions beyond what is explicitly listed). The eligibility language also explicitly included a wide range of institution types such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and Asian American Native American Pacific Islander Serving Institutions, along with faith-based and community-based organizations and eligible federal agencies. At the same time, the opportunity clearly excluded non-U.S. entities: foreign institutions could not apply, non-U.S. components of U.S. organizations were not eligible, and foreign components (as defined by NIH policy) were not allowed.
Overall, the TACTIC (UM1) opportunity was built to accelerate progress in understanding and ultimately improving management of trauma induced coagulopathy by deliberately pairing access to clinically collected trauma trial samples with integrated, collaborative basic research. The single-award consortium model, the NHLBI-DoD partnership, and the cooperative agreement structure all point to an initiative aimed at coordinated, high-impact science that can connect mechanistic discoveries to urgent clinical needs in trauma care. For full details, the announcement was hosted on the NIH grants site (RFA-HL-13-025), and NIH provided standard support contacts for access and linking issues through the NIH Office of Extramural Research webmaster.
Frequently Asked Questions (FAQs)
What is the TACTIC (UM1) funding opportunity?
TACTIC stands for the Trans Agency Research Consortium for Trauma Induced Coagulopathy. It is an NIH funding opportunity designed to create one coordinated, multi-component basic research program focused on trauma induced coagulopathy (TIC).
What is trauma induced coagulopathy (TIC), and why is it important?
TIC is a serious bleeding and clotting disorder that can develop after major trauma. It is described as a major contributor to preventable death in both civilian and military settings, which is why understanding its mechanisms and improving outcomes is a central goal of this program.
What does it mean that this award mechanism is a cooperative agreement (UM1)?
A UM1 cooperative agreement means the funded consortium would not simply receive funds and operate independently. Instead, the research would be carried out in close collaboration with the sponsoring agencies, with substantial scientific and programmatic involvement from the government partners.
Which agencies support TACTIC?
TACTIC is jointly supported by the National Heart, Lung and Blood Institute (NHLBI) and the Department of Defense (DoD), reflecting its trans-agency structure.
What is meant by a “trans-agency†consortium?
“Trans-agency†indicates the program is structured across multiple government partners (here, NHLBI and DoD) and is intended to function as a coordinated consortium rather than isolated projects.
How does the program connect “bench-to-bedside†research?
The opportunity is intended to link ongoing trauma trials to mechanistic laboratory science by connecting clinical investigators conducting DoD-funded trauma-related clinical trials with basic scientists funded under the UM1 research program.
What kinds of samples or data is the program intended to leverage?
In practical terms, the UM1 program is meant to take advantage of real-world, well-characterized patient samples collected through ongoing DoD-funded clinical studies, enabling hypothesis-driven investigations into TIC.
What types of research projects does TACTIC emphasize?
The program emphasizes hypothesis-driven, mechanistic, and experimentally rigorous studies aimed at understanding why TIC develops, how it changes over time, and which biological pathways might be targeted to improve outcomes.
Is this opportunity intended for multiple independent awards or a single coordinated program?
It anticipated making a single award, signaling that the intent was to form one unified consortium rather than fund multiple independent projects.
What is the Funding Opportunity Number (FOA) for this program?
The Funding Opportunity Number listed for this program is RFA-HL-13-025.
How is this opportunity categorized?
It is categorized under health and is tied to CFDA 93.839 (Blood Diseases and Resources Research).
How much funding was anticipated under this opportunity?
The estimated total funding level was $24,000,000, with an award ceiling of $4,800,000.
Was cost sharing or matching required?
No. The opportunity stated there was no cost sharing or matching requirement.
When was the opportunity posted and when were applications due?
The announcement was posted on November 21, 2012, and the application due date was February 6, 2013.
Is this funding opportunity still open?
No. The announcement was later archived on March 9, 2013.
Who was eligible to apply?
Eligibility was broad across U.S.-based organizations, including various types of state and local governments, certain tribal governments, public and private institutions of higher education, independent school districts, public housing authorities/Indian housing authorities, nonprofits (with and without 501(c)(3) status), and for-profit organizations (including small businesses). The eligibility language also included a wide range of institution types such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and Asian American Native American Pacific Islander Serving Institutions, along with faith-based and community-based organizations and eligible federal agencies.
Are foreign organizations eligible to apply?
No. The opportunity excluded non-U.S. entities: foreign institutions could not apply, non-U.S. components of U.S. organizations were not eligible, and foreign components (as defined by NIH policy) were not allowed.
Where could applicants find the full announcement and official details?
The full details were hosted on the NIH grants site under RFA-HL-13-025.
Who could be contacted for technical issues related to accessing or linking the announcement?
NIH provided standard support contacts for access and linking issues through the NIH Office of Extramural Research webmaster.
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