Opportunity Information: Apply for PA 08 161
Apply for PA 08 161
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Transdisciplinary Research on Fatigue and Fatigability in Aging (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213 Research and Training in Complementary and Integrative Health 93.361 Nursing Research 93.393 Cancer Cause and Prevention Research 93.866 Aging Research.
- This funding opportunity was created on Dec 5, 2008 and posted on Apr 25, 2008.
- Applicants must submit their applications by May 7, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments Small businesses Public and State controlled institutions of higher education State governments For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) County governments Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Transdisciplinary Research on Fatigue and Fatigability in Aging (R01) opportunity (Funding Opportunity Number PA-08-161) is a National Institutes of Health (NIH) funding announcement focused on improving scientific understanding of fatigue and fatigability as they relate to aging. Its central aim is to stimulate research that looks beyond a single discipline or body system and instead brings together transdisciplinary teams and methods to clarify why fatigue and increased fatigability occur in older adults, how to measure them more accurately, and how to prevent or reduce them through effective interventions. The scope is broad in terms of scientific approach and allows for studies in humans as well as in animal models, as long as the work directly informs fatigue or fatigability in the context of aging.
A key theme of the announcement is mechanism, measurement, and intervention. On the mechanism side, the FOA encourages projects that can uncover biological, behavioral, psychological, and social contributors to fatigue and fatigability in later life, including how multiple systems interact to produce symptoms and functional limitations. On the assessment side, it supports research aimed at improving how fatigue and fatigability are defined, captured, and quantified, which can include novel instruments, objective performance-based measures, biomarkers, or combined approaches that link subjective experience with functional outcomes. On the intervention side, the FOA invites studies that test strategies to lessen fatigue or reduce fatigability in older people, which could involve clinical, behavioral, rehabilitative, integrative, or other approaches appropriate to the research question and the targeted mechanisms.
The funding mechanism is the NIH Research Project Grant (R01), which is generally used for mature, hypothesis-driven projects with a well-developed research plan. This FOA is explicitly paired with a companion announcement of the same scientific scope that uses the Exploratory/Developmental (R21) mechanism (PA-08-162). In practical terms, the R01 track is meant for more fully developed projects, while the parallel R21 track accommodates earlier-stage or high-risk/high-reward exploratory work, even though both are centered on the same overarching topic of fatigue and fatigability in aging.
Funding under this announcement is described as contingent on the availability of funds and on the receipt of a sufficient number of scientifically strong applications. In other words, the NIH did not promise a fixed number of awards; instead, awards would be made based on budget conditions and the merit of the applications received.
The program is categorized as discretionary and uses the grant funding instrument type, with an activity focus aligned with education and health. It is associated with several CFDA program areas, reflecting the cross-cutting nature of fatigue research across NIH interests: 93.866 (Aging Research), 93.361 (Nursing Research), 93.393 (Cancer Cause and Prevention Research), and 93.213 (Research and Training in Complementary and Integrative Health). The announcement states there is no cost sharing or matching requirement, which means applicants are not required to contribute a specified portion of project costs from non-federal sources as a condition of award.
Eligibility is broad and includes many types of applicant organizations. Eligible applicants include public and private institutions of higher education, nonprofit organizations (including both 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (including small businesses and other for-profits), and a wide range of government entities such as state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities. The eligibility language also explicitly includes tribal governments (both federally recognized and other than federally recognized) and tribal organizations, as well as tribally controlled colleges and universities. In addition, the announcement lists other eligible groups such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and non-U.S. entities (foreign organizations), indicating an intent to encourage participation from a diverse range of institutions and communities.
Administratively, the FOA was posted on April 25, 2008, with a closing date of May 7, 2011, and it was later archived on June 7, 2011. The full announcement was made available through the NIH Grants Guide, and the notice provides contact support through the NIH Office of Extramural Research (OER) webmaster for access or linking issues.
Frequently Asked Questions (FAQs): Transdisciplinary Research on Fatigue and Fatigability in Aging (R01) - PA-08-161
What is the name and funding opportunity number of this grant?
The opportunity is titled Transdisciplinary Research on Fatigue and Fatigability in Aging (R01). The Funding Opportunity Number (FOA) is PA-08-161.
Which agency is offering this funding opportunity?
This is a National Institutes of Health (NIH) funding announcement.
What is the main purpose of this FOA?
The central purpose is to improve scientific understanding of fatigue and fatigability in the context of aging by stimulating research that goes beyond a single discipline or body system and instead uses transdisciplinary teams and methods.
What does the FOA mean by "transdisciplinary" research?
Based on the announcement description, "transdisciplinary" refers to research that looks beyond one discipline or one body system and brings together multiple perspectives, teams, and methods to clarify why fatigue and increased fatigability occur in older adults, how to measure them, and how to prevent or reduce them.
What topics or themes does the FOA emphasize?
The FOA highlights three major themes: mechanisms (why fatigue/fatigability happens), measurement/assessment (how to define and quantify it), and interventions (how to prevent or reduce it in older adults).
What kinds of mechanisms are of interest under this announcement?
The FOA encourages projects that uncover biological, behavioral, psychological, and social contributors to fatigue and fatigability in later life, including how multiple systems interact to produce symptoms and functional limitations.
What types of measurement or assessment work does this FOA support?
The FOA supports improving how fatigue and fatigability are defined, captured, and quantified. Examples mentioned include novel instruments, objective performance-based measures, biomarkers, or combined approaches that connect subjective experience to functional outcomes.
What types of intervention studies are encouraged?
The FOA invites studies that test strategies to lessen fatigue or reduce fatigability in older people, including clinical, behavioral, rehabilitative, integrative, or other approaches that fit the research question and the mechanisms being targeted.
Are both human and animal studies allowed?
Yes. The scope allows studies in humans as well as animal models, as long as the work directly informs fatigue or fatigability in the context of aging.
What is the funding mechanism for PA-08-161?
The funding mechanism is the NIH Research Project Grant (R01), which is generally used for mature, hypothesis-driven projects with a well-developed research plan.
Is there a related or companion FOA for exploratory projects?
Yes. This FOA is paired with a companion announcement using the R21 mechanism: PA-08-162, with the same scientific scope but intended for earlier-stage or high-risk/high-reward exploratory work.
How does the R01 track differ from the companion R21 track (based on this description)?
In practical terms, the R01 track is intended for more fully developed projects, while the parallel R21 track accommodates earlier-stage or exploratory research, even though both address fatigue and fatigability in aging.
Does the FOA guarantee a fixed number of awards?
No. Funding is described as contingent on the availability of funds and on receiving a sufficient number of scientifically strong applications. The NIH did not promise a fixed number of awards in the information provided.
Is cost sharing or matching required?
No. The announcement states there is no cost sharing or matching requirement.
What type of program and funding instrument is this?
The program is categorized as discretionary and uses the grant funding instrument type.
What activity focus is associated with this opportunity?
The activity focus is aligned with education and health, as described in the opportunity summary.
Which CFDA program areas are associated with this FOA?
The announcement is associated with multiple CFDA program areas: 93.866 (Aging Research), 93.361 (Nursing Research), 93.393 (Cancer Cause and Prevention Research), and 93.213 (Research and Training in Complementary and Integrative Health).
Who is eligible to apply?
Eligibility is broad. Eligible applicants include public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (including small businesses), and many types of government entities (state, county, city/township, special district governments, independent school districts, and public housing authorities/Indian housing authorities).
Are tribal governments and tribal organizations eligible?
Yes. The eligibility language explicitly includes tribal governments (federally recognized and other than federally recognized) and tribal organizations, as well as tribally controlled colleges and universities.
Are minority-serving institutions and community-based organizations included in eligibility?
Yes. The announcement lists eligible groups such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, as well as faith-based or community-based organizations and regional organizations.
Are U.S. territories and non-U.S. entities eligible?
Yes. Eligibility includes U.S. territories or possessions and non-U.S. entities (foreign organizations).
When was this FOA posted, and what was the closing date?
The FOA was posted on April 25, 2008, and the closing date listed is May 7, 2011.
Is this opportunity still open?
No. The announcement was later archived on June 7, 2011, which indicates it is no longer an active, open opportunity.
Where was the full announcement made available?
The full announcement was made available through the NIH Grants Guide.
Who is listed for support if there are access or linking issues?
The notice provides contact support through the NIH Office of Extramural Research (OER) webmaster for access or linking issues.
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| Diet Induced Changes in Inflammation as Determinants of Colon Cancer (R01) Apply for PA 08 210 Funding Number: PA 08 210 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Diet Induced Changes in Inflammation as Determinants of Colon Cancer (R21) Apply for PA 08 211 Funding Number: PA 08 211 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Drug Abuse Prevention Intervention Research (R01) Apply for PA 08 217 Funding Number: PA 08 217 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Drug Abuse Prevention Intervention Research (R21) Apply for PA 08 218 Funding Number: PA 08 218 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
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