Opportunity Information: Apply for PAR 10 141
Apply for PAR 10 141
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Transforming Biomedicine at the Interface of the Life and Physical Sciences (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.859 Biomedical Research and Research Training.
- This funding opportunity was created on Mar 18, 2010 and posted on Mar 18, 2010.
- Applicants must submit their applications by May 18, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education Public and State controlled institutions of higher education For profit organizations other than small businesses Native American tribal governments (Federally recognized).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) .
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Opportunity Summary:
Transforming Biomedicine at the Interface of the Life and Physical Sciences (R01) (Funding Opportunity Number PAR-10-141) is a discretionary grant opportunity led by the National Institutes of Health in partnership with the National Science Foundation. Its core aim is to push biomedical research forward by bringing together teams that span the quantitative and physical sciences (such as physics, engineering, mathematics, computer science, chemistry, and related areas) with biomedical scientists. The emphasis is on translating advances in quantitative and physical science knowledge into practical biomedical impact, specifically by creating entirely new health care devices or systems or meaningfully improving existing ones. In other words, the program is designed to encourage cross-disciplinary work where rigorous quantitative thinking and physical science methods directly shape next-generation tools, platforms, and approaches that can improve human health.
The funding uses the NIH R01 mechanism, which is the standard, investigator-initiated research project grant intended to support discrete, specified projects. The announcement signals flexibility rather than a fixed award size: budgets and project periods are expected to vary depending on what is scientifically and technically appropriate for each application. There is no single stated pot of money or guaranteed number of awards; instead, the total number of funded projects and total dollars awarded depend on the quality of submissions, the proposed duration, and the requested costs. This structure is typical of broad NIH research solicitations that cover a wide range of possible project types and scopes, especially in interdisciplinary areas where resource needs can differ greatly from one approach to another.
This opportunity falls under health-related funding activity categories and is associated with multiple CFDA numbers, indicating relevance across several NIH program areas. The CFDA listings include 93.286 (Discovery and Applied Research for Technological Innovations to Improve Human Health), 93.846 (Arthritis, Musculoskeletal and Skin Diseases Research), and 93.859 (Biomedical Research and Research Training). Practically, this signals that proposed work may align with general biomedical technology innovation as well as disease- or institute-specific missions, and that the underlying research can range from foundational, enabling technology development to applied systems that address real biomedical needs.
Eligibility is broad and includes many organization types across the nonprofit, academic, governmental, and private sectors. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status, excluding higher education institutions in those specific nonprofit categories), small businesses, and for-profit organizations other than small businesses. The announcement also explicitly includes tribal entities and related organizations, such as federally recognized Native American tribal governments and Native American tribal organizations, along with tribally controlled colleges and universities. Additional eligible applicants listed include Alaska Native and Native Hawaiian Serving Institutions, Hispanic Serving Institutions, Historically Black Colleges and Universities (HBCUs), faith-based or community-based organizations, regional organizations, and even non-U.S. (foreign) entities. It also notes that eligible federal agencies may apply. The opportunity does not require cost sharing or matching funds, reducing barriers for organizations that might otherwise struggle to meet a matching requirement.
Key timeline details show that the opportunity was posted and created on March 18, 2010, with an original and current closing date of May 18, 2012, and an archive date of June 18, 2012. That indicates the solicitation is no longer active, but the summary still captures the program’s intent and structure. For applicants or researchers trying to track the original announcement details, the NIH listing is referenced through an additional information link to the NIH Grants Guide page for PAR-10-141. Contact support in the source text points to the NIH Office of Extramural Research (OER) webmaster for technical issues accessing the announcement online or problems linking to the funding notice.
Overall, the grant is best understood as a deliberate push to make biomedical progress by blending disciplines: taking advances in quantitative and physical sciences and turning them into tangible biomedical devices and systems that can change how health care is delivered, measured, or understood. The R01 format and variable award sizing suggest it was meant to support substantial, research-driven development efforts that require serious collaboration across scientific cultures, from conceptual frameworks and modeling to prototyping, system design, and performance validation in biomedical contexts.
Frequently Asked Questions (FAQs)
What is the name of this grant opportunity?
The opportunity is titled Transforming Biomedicine at the Interface of the Life and Physical Sciences (R01).
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is PAR-10-141.
Which agencies are leading or partnering on this opportunity?
This is a discretionary grant opportunity led by the National Institutes of Health (NIH) in partnership with the National Science Foundation (NSF).
What is the main goal of the program?
The core aim is to push biomedical research forward by bringing together cross-disciplinary teams that span the quantitative and physical sciences with biomedical scientists, and to translate advances from those fields into practical biomedical impact.
What kinds of research approaches does the program emphasize?
The program emphasizes research where rigorous quantitative thinking and physical science methods directly shape next-generation biomedical tools, platforms, and approaches intended to improve human health.
What types of outcomes is this opportunity trying to support?
The emphasis is on creating entirely new health care devices or systems or meaningfully improving existing devices or systems, with clear biomedical relevance.
Which scientific disciplines are specifically mentioned as part of the intended team makeup?
The announcement highlights quantitative and physical sciences such as physics, engineering, mathematics, computer science, chemistry, and related areas, working together with biomedical scientists.
What funding mechanism is used?
The opportunity uses the NIH R01 mechanism, which is the standard investigator-initiated research project grant intended to support a discrete, specified project.
Is there a fixed award size or fixed project period?
No. The announcement signals flexibility rather than a single fixed award size. Budgets and project periods are expected to vary depending on what is scientifically and technically appropriate for each application.
Is there a guaranteed number of awards or a stated total funding amount?
No. There is no single stated pot of money and no guaranteed number of awards. The total number of funded projects and total dollars awarded depend on the quality of submissions, proposed duration, and requested costs.
What funding activity category does this opportunity fall under?
It falls under health-related funding activity categories.
Which CFDA numbers are associated with this opportunity?
The opportunity is associated with multiple CFDA numbers, including:
- 93.286 - Discovery and Applied Research for Technological Innovations to Improve Human Health
- 93.846 - Arthritis, Musculoskeletal and Skin Diseases Research
- 93.859 - Biomedical Research and Research Training
What does it mean that multiple CFDA numbers are listed?
The multiple CFDA listings indicate relevance across several NIH program areas. Practically, it signals that proposed work may align with general biomedical technology innovation as well as disease- or institute-specific missions, and that the research can range from foundational enabling technology development to applied systems addressing real biomedical needs.
Who is eligible to apply?
Eligibility is broad and includes many organization types across the nonprofit, academic, governmental, and private sectors. Eligible applicants include:
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Nonprofit organizations (with and without 501(c)(3) status, in the specified nonprofit categories excluding higher education institutions)
- Small businesses
- For-profit organizations other than small businesses
- Federally recognized Native American tribal governments
- Native American tribal organizations
- Tribally controlled colleges and universities
- Alaska Native and Native Hawaiian Serving Institutions
- Hispanic Serving Institutions
- Historically Black Colleges and Universities (HBCUs)
- Faith-based or community-based organizations
- Regional organizations
- Non-U.S. (foreign) entities
- Eligible federal agencies
Are non-U.S. (foreign) organizations eligible?
Yes. The eligibility list explicitly includes non-U.S. (foreign) entities.
Are tribal governments and tribal organizations eligible?
Yes. The opportunity explicitly includes federally recognized Native American tribal governments, Native American tribal organizations, and tribally controlled colleges and universities.
Does the opportunity require cost sharing or matching funds?
No. The opportunity states that it does not require cost sharing or matching funds.
When was this opportunity posted and created?
The opportunity was posted and created on March 18, 2010.
What was the closing date for applications?
The original and current closing date listed is May 18, 2012.
What is the archive date, and what does it suggest?
The archive date is June 18, 2012. This timeline indicates the solicitation is no longer active.
Where can someone find the original NIH announcement details?
The summary references an additional information link to the NIH Grants Guide page for PAR-10-141.
Who is listed for technical support related to accessing the notice online?
For technical issues accessing the announcement online or problems linking to the funding notice, the source text points to the NIH Office of Extramural Research (OER) webmaster.
In plain terms, what kind of projects did this program intend to enable?
It was designed as a deliberate push to blend disciplines and convert advances in quantitative and physical sciences into tangible biomedical devices and systems that could change how health care is delivered, measured, or understood, typically through substantial, research-driven development efforts requiring serious cross-disciplinary collaboration.
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