Opportunity Information: Apply for PAR 14 245
Apply for PAR 14 245
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Translational Programs in Lung Diseases (P01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.233 National Center on Sleep Disorders Research 93.838 Lung Diseases Research.
- This funding opportunity was created on Jun 3, 2014 and posted on Jun 3, 2014.
- Applicants must submit their applications by May 19, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,750,000.00 in funding.
- Eligible applicants include: Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized) County governments City or township governments State governments Special district governments Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Small businesses For profit organizations other than small businesses.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NIH Funding Opportunity Announcement PAR-14-245, titled "Translational Programs in Lung Diseases (P01)," supports large, multi-project Program Project Grant (P01) applications focused on collaborative, translational research in lung diseases and sleep disorders. The central idea is to move beyond isolated projects and instead fund coordinated research programs that connect mechanistic, biology-driven discoveries to practical clinical applications. The FOA emphasizes using a deep understanding of disease mechanisms as the foundation for the rational design of improved approaches to prevention, diagnosis, and treatment. In practice, this means the program is aimed at research teams that can demonstrate a clear pathway from fundamental mechanistic insights to tools, strategies, or interventions that could ultimately be used in clinical settings.
This opportunity is administered by the National Institutes of Health and aligns with NIH interests in lung diseases research and sleep disorders research, reflected in CFDA numbers 93.838 (Lung Diseases Research) and 93.233 (National Center on Sleep Disorders Research). The funding mechanism is a discretionary grant, and it specifically uses the Program Project (P01) structure, which is designed for research programs that require multiple, interrelated projects working together under a unifying theme. A competitive application under this mechanism typically involves a clearly articulated overarching scientific vision, several tightly connected research projects that depend on each other scientifically, and shared cores or resources that improve efficiency and integration across the program. The FOA is oriented toward applicants who can justify why a coordinated, team-based P01 structure is necessary to achieve the translational goals, rather than proposing work that could be done as separate standalone grants.
The FOA does not require cost sharing or matching funds, which reduces the financial barriers for institutions and organizations that may not have discretionary resources to contribute to the project budget. The listed award ceiling is $1,750,000, signaling that NIH anticipated relatively substantial budgets consistent with multi-project, resource-intensive translational programs. As a translational P01, the expectation is generally that the funded program would bring together complementary expertise, such as basic scientists, translational researchers, clinical investigators, and potentially biostatistics, informatics, or technology development teams, depending on the disease area and the nature of the clinical application being pursued.
Eligibility for this opportunity is broad. Eligible applicants include a wide range of public and private institutions of higher education, nonprofit organizations (including both 501(c)(3) and non-501(c)(3) entities), for-profit organizations (including small businesses and other for-profits), and multiple levels of government organizations (state, local, county, city/township, special district governments, and certain housing authorities). The announcement also explicitly includes tribal governments and tribal organizations, and it highlights eligibility for institutions and organizations that serve specific communities, such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs). Faith-based and community-based organizations and regional organizations are also identified among eligible applicant types. Importantly, non-domestic components of U.S. organizations are eligible to apply, and foreign components are allowed as defined by the NIH Grants Policy Statement, which indicates NIH was open to international collaboration when it strengthens the scientific or translational impact of the program.
Key dates show that the FOA was posted on June 3, 2014, with an original and final closing date of May 19, 2017, and an archive date of June 19, 2017. That means the announcement is no longer active for new submissions, but it remains relevant as a reference for the scope and expectations NIH had for translational lung disease and sleep disorder program projects during that period, and it may also be useful to groups preparing for similar future NIH opportunities under related mechanisms.
For those seeking official details, the announcement points to the NIH grants guide page at http://grants.nih.gov/grants/guide/pa-files/PAR-14-245.html. Administrative support contacts are routed through the NIH Office of Extramural Research (OER) webmaster, with provided email addresses for technical access issues. Overall, PAR-14-245 was designed to fund integrated, collaborative translational research programs that connect mechanistic discovery to clinically meaningful advances in lung diseases and sleep disorders, using the multi-project P01 structure to support teams whose combined efforts are stronger than the sum of their parts.
FAQs: NIH PAR-14-245 - Translational Programs in Lung Diseases (P01)
What is PAR-14-245?
PAR-14-245 is an NIH Funding Opportunity Announcement (FOA) titled "Translational Programs in Lung Diseases (P01)." It supported large, multi-project Program Project Grant (P01) applications focused on collaborative, translational research in lung diseases and sleep disorders.
What is the main goal of this FOA?
The central goal was to fund coordinated research programs that move beyond isolated projects by linking mechanistic, biology-driven discoveries to practical clinical applications. The FOA emphasized using deep understanding of disease mechanisms to rationally design improved approaches to prevention, diagnosis, and treatment.
What kinds of research were encouraged?
The FOA emphasized translational research programs where teams could show a clear pathway from fundamental mechanistic insights to tools, strategies, or interventions that could ultimately be used in clinical settings, specifically in lung diseases and sleep disorders.
What is the funding mechanism used in this opportunity?
This opportunity used the NIH Program Project (P01) mechanism, a discretionary grant structure designed for multiple, interrelated projects organized around a unifying theme.
What makes a P01 different from separate standalone grants?
Under this FOA, applicants were expected to justify why a coordinated, team-based P01 structure was necessary to achieve the translational goals, rather than proposing work that could be done as independent, unrelated projects under separate awards.
What does NIH typically expect in a competitive P01 application under this FOA?
A competitive program typically included (1) a clearly articulated overarching scientific vision, (2) several tightly connected research projects that depend on each other scientifically, and (3) shared cores or resources that improve efficiency and integration across the program.
What disease areas did this FOA focus on?
The FOA focused on lung diseases research and sleep disorders research.
Which NIH-related program areas or CFDA numbers were associated with this FOA?
The FOA aligned with CFDA 93.838 (Lung Diseases Research) and CFDA 93.233 (National Center on Sleep Disorders Research).
What is meant by "translational" in the context of this FOA?
In this FOA, translational work meant connecting mechanistic discovery (how disease works at a fundamental level) to clinically meaningful advances, such as improved prevention, diagnosis, or treatment approaches.
What level of collaboration did this FOA anticipate?
The FOA was designed for collaborative teams and anticipated bringing together complementary expertise such as basic scientists, translational researchers, clinical investigators, and potentially biostatistics, informatics, or technology development teams, depending on the program's clinical application goals.
Was cost sharing or matching funds required?
No. The FOA did not require cost sharing or matching funds.
What was the award ceiling?
The listed award ceiling was $1,750,000, reflecting NIH expectations for relatively substantial, multi-project, resource-intensive translational programs.
Who was eligible to apply?
Eligibility was broad and included public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and non-501(c)(3)), for-profit organizations (including small businesses and other for-profits), and multiple levels of government organizations (state, local, county, city/township, special district governments, and certain housing authorities).
Were tribal entities eligible?
Yes. Tribal governments and tribal organizations were explicitly included among eligible applicant types.
Were community-serving and minority-serving institutions eligible?
Yes. The FOA specifically highlighted eligibility for institutions and organizations serving specific communities, including HBCUs, Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and AANAPISIs.
Could faith-based or community-based organizations apply?
Yes. Faith-based and community-based organizations were identified among eligible applicant types.
Were regional organizations eligible?
Yes. Regional organizations were listed among eligible applicant types.
Were non-U.S. components allowed?
Yes. Non-domestic components of U.S. organizations were eligible to apply, and foreign components were allowed as defined by the NIH Grants Policy Statement, supporting international collaboration when it strengthens the scientific or translational impact.
Is this funding opportunity still open?
No. The FOA is no longer active for new submissions. It was posted on June 3, 2014; its original and final closing date was May 19, 2017; and it has an archive date of June 19, 2017.
Why might PAR-14-245 still be useful if it is archived?
Although it is not open for new submissions, it can still serve as a reference for the scope and expectations NIH had for translational lung disease and sleep disorder program projects during that period, and it may help groups preparing for similar NIH opportunities under related mechanisms.
Where can applicants find the official FOA text?
The official NIH grants guide listing is available at: http://grants.nih.gov/grants/guide/pa-files/PAR-14-245.html.
Who is listed as a contact for administrative or technical access issues?
Administrative support contacts were routed through the NIH Office of Extramural Research (OER) webmaster, with email addresses provided for technical access issues in the announcement.
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