Translational Research to Improve Diabetes and Obesity Outcomes (R01) | Apply Online

Opportunity Summary:

The grant opportunity titled "Translational Research to Improve Diabetes and Obesity Outcomes (R01)" (Funding Opportunity Number PA-13-352) is an NIH Research Project Grant announcement designed to move proven diabetes and obesity interventions closer to real-world use. The focus is on taking strategies that already have evidence of efficacy and adapting them so they work better in practical settings, remain sustainable over time, and are cost efficient. In other words, the FOA is less about discovering entirely new biological mechanisms and more about improving how effective prevention and treatment approaches can be delivered, maintained, and scaled in everyday clinical or community environments.

The FOA encourages research aimed at several major outcome areas: preventing or reversing obesity, preventing type 2 diabetes, improving care for people with type 1 diabetes and type 2 diabetes, and preventing or delaying complications associated with these conditions. A key theme is implementation potential beyond academia. NIH is signaling that proposed interventions should be built with dissemination in mind, meaning they should be feasible in routine clinical practice, public health programs, and community settings, especially those serving populations at elevated risk. Projects are expected to test adaptations that make interventions workable under real constraints such as limited staffing, time, infrastructure, and budgets, while still preserving meaningful health benefits.

This opportunity uses the R01 mechanism, which supports a defined research project and typically allows investigators to propose a multi-year plan with clear aims, study design, and measurable outcomes. The activity category is listed under Food and Nutrition/Health, and it falls under CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), reflecting NIH's interest in practical translational work that can improve population health related to diabetes and obesity.

Eligibility is broad and includes many types of U.S.-based organizations across the public, private, and nonprofit sectors. Eligible applicants include state, county, city or township, and special district governments; public and private institutions of higher education; independent school districts; public housing authorities/Indian housing authorities; small businesses; and for-profit organizations other than small businesses. Nonprofits are eligible whether or not they have 501(c)(3) status (with the caveat noted in the listing), and multiple categories of tribal entities are included, such as federally recognized tribal governments and other Native American tribal organizations. The FOA also explicitly includes a range of mission-driven and capacity-building institutions and organizations as eligible, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations and certain eligible federal agencies. At the same time, the announcement makes clear that non-U.S. entities are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed, keeping the work fully domestic in scope.

Administrative details show that this is a discretionary grant program administered by the National Institutes of Health, with no cost sharing or matching requirement. The FOA was posted and created on September 12, 2013, with an original and current closing date of January 7, 2017, and an archive date of February 7, 2017, meaning the specific announcement is no longer open for application in its listed form. The full archived announcement was hosted at the NIH grants page (link provided in the source), and NIH’s Office of Extramural Research (OER) webmaster contact was provided for access or technical issues related to the posting.

Overall, the heart of PA-13-352 is practical translation: testing adaptations of interventions that already work so they can work at scale, at reasonable cost, and in the real settings where most people receive care or support. The strongest-fit projects under this kind of FOA are typically those that can demonstrate not only health impact (for obesity, diabetes prevention, diabetes management, or complication reduction), but also feasibility, sustainability, and a clear pathway for broader adoption in clinics and communities.

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