Opportunity Information: Apply for RFA AI 11 001
Apply for RFA AI 11 001
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Tropical Medicine Research Centers (P50)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research.
- This funding opportunity was created on Oct 18, 2010 and posted on Oct 18, 2010.
- Applicants must submit their applications by May 12, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,900,000.00 to eligible and selected applicants.
- Eligible applicants include: State governments Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Independent school districts Public and State controlled institutions of higher education County governments City or township governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) .
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Opportunity Summary:
The Tropical Medicine Research Centers (P50) funding opportunity (RFA-AI-11-001) is a discretionary grant program from the National Institute of Allergy and Infectious Diseases (NIAID) at the National Institutes of Health (NIH). It is designed to support center-based research efforts focused on tropical diseases in endemic settings, with an explicit emphasis on work that can be carried out where these diseases occur and on strengthening local, in-country research capacity. In practical terms, the program is looking for institutions and organizations that can build a coordinated research center capable of tackling real-world problems tied to neglected tropical diseases, while also leaving behind sustainable scientific infrastructure, expertise, and partnerships in the affected regions.
The scientific scope is intentionally focused and does not cover all tropical diseases broadly. Instead, it is limited to Neglected Tropical Diseases (NTDs) and the vectors that transmit them. Proposed research can address the causes of disease (including biological mechanisms and transmission dynamics), methods to improve diagnosis, strategies to prevent infection or reduce transmission, and approaches to treatment. Applicants may concentrate on a single NTD pathogen or take on multiple pathogens, and the announcement explicitly encourages multidisciplinary projects and/or multi-pathogen portfolios. That means proposals that blend fields like microbiology, immunology, clinical research, epidemiology, entomology/vector biology, public health implementation, and health systems work are aligned with the stated intent, particularly when the combined approach makes the center stronger than a set of disconnected individual projects.
A central theme of the opportunity is conducting research in endemic areas and simultaneously creating and sustaining local capacity. This goes beyond simply running studies overseas; it points toward durable partnerships, training, and infrastructure development that enable continued high-quality research within the country or region where the NTD burden exists. Competitive applications would typically be expected to show how they will support and retain local investigators, strengthen laboratories or field sites, improve data and sample management, and build administrative and regulatory capabilities needed for ongoing research (for example, ethics review processes, clinical research operations, and reliable field surveillance). The overall direction is toward research centers that produce strong science and also help close long-standing gaps in research capacity in settings most affected by NTDs.
The program uses the NIH P50 center grant mechanism, which generally implies an integrated center structure rather than a single stand-alone project. While the announcement text provided here does not list detailed component requirements, P50 opportunities commonly support multiple interrelated research projects under a unified theme, supported by shared resources or cores that benefit the whole center. The emphasis on multidisciplinary and multi-pathogen research fits well with a center model where teams can share platforms such as clinical cohorts, vector surveillance systems, diagnostic labs, biostatistics and data management, or training and capacity-building activities.
From an administrative and eligibility standpoint, the opportunity was posted on October 18, 2010, with an original and current closing date of May 12, 2011, and an archive date of June 12, 2011. The estimated total funding amount listed is $2,900,000, and there is no cost sharing or matching requirement. The funding activity falls under health, with CFDA numbers 93.855 (Allergy, Immunology and Transplantation Research) and 93.856 (Microbiology and Infectious Diseases Research), reflecting the NIAID scientific mission areas most closely tied to NTD research.
Eligibility is broad and includes many types of U.S. domestic organizations and governments, such as state, county, and city/township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; nonprofits with or without 501(c)(3) status (other than institutions of higher education); for-profit organizations (including those other than small businesses, and small businesses specifically); and additional categories noted in the announcement. The FOA also explicitly includes a wide range of mission-driven and underrepresented institution types and community-focused entities, including Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and notably non-U.S. entities (foreign organizations) and regional organizations. That breadth aligns with the program goal of supporting work in endemic regions and suggests that strong applications could be led either by U.S. institutions partnering abroad or by eligible foreign or regional organizations capable of hosting and sustaining the center activities in-country.
For applicants seeking the full official announcement, the source points to the NIH Grants Guide page at http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-11-001.html. Administrative help for accessing or linking to the announcement is routed through the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV. Overall, this FOA is best understood as a targeted NIH center grant aimed at advancing research on NTDs and their vectors while deliberately building long-term research strength in the places where these diseases are most entrenched.
Frequently Asked Questions (FAQs): Tropical Medicine Research Centers (P50) - RFA-AI-11-001
What is the Tropical Medicine Research Centers (P50) funding opportunity?
It is a discretionary grant program from the National Institute of Allergy and Infectious Diseases (NIAID) at the National Institutes of Health (NIH). The opportunity supports center-based research efforts focused on tropical diseases in endemic settings, with an explicit emphasis on conducting work where these diseases occur while strengthening in-country research capacity.
What is the FOA number for this opportunity?
The funding opportunity announcement (FOA) is RFA-AI-11-001.
What grant mechanism is used for this program?
This program uses the NIH P50 center grant mechanism, which is designed for an integrated center structure rather than a single stand-alone project.
What is the main purpose of this program?
The program is intended to support coordinated research centers that address real-world problems tied to neglected tropical diseases (NTDs) and their vectors, while also leaving behind sustainable scientific infrastructure, expertise, and partnerships in the regions most affected.
Which diseases are within the scientific scope of this FOA?
The scope is intentionally limited to Neglected Tropical Diseases (NTDs) and the vectors that transmit them. It is not a broad tropical diseases program covering all tropical diseases.
Are vector-related studies allowed under this FOA?
Yes. The FOA explicitly includes NTDs and the vectors that transmit them, so research involving vector biology and transmission is within scope.
What kinds of research topics are supported?
Supported topics include research on causes of disease (such as biological mechanisms and transmission dynamics), improved diagnostic methods, prevention strategies (including reducing transmission), and approaches to treatment.
Can an applicant focus on a single pathogen, or must they cover multiple pathogens?
Applicants may concentrate on a single NTD pathogen or address multiple pathogens. The announcement encourages multidisciplinary projects and/or multi-pathogen portfolios.
Does the FOA encourage multidisciplinary research?
Yes. Proposals that blend disciplines such as microbiology, immunology, clinical research, epidemiology, entomology/vector biology, public health implementation, and health systems work are aligned with the FOA intent, especially when the integrated approach strengthens the center beyond disconnected projects.
Is research required to be conducted in endemic settings?
A central theme is conducting research in endemic areas, with an emphasis on work that can be carried out where the diseases occur.
What does "building local capacity" mean in the context of this FOA?
Capacity building goes beyond running studies overseas. The FOA points toward durable partnerships, training, and infrastructure development that enable continued high-quality research within the affected country or region. Examples mentioned include supporting and retaining local investigators, strengthening laboratories or field sites, improving data and sample management, and building administrative and regulatory capabilities (such as ethics review processes, clinical research operations, and reliable field surveillance).
What kind of center structure is implied by a P50 award?
A P50 generally implies multiple interrelated research projects under a unified theme, supported by shared resources or cores that benefit the entire center. While the provided summary does not list detailed component requirements, it describes a center model where teams can share platforms such as clinical cohorts, vector surveillance systems, diagnostic labs, biostatistics and data management, and training/capacity-building activities.
What is the estimated total funding amount for this FOA?
The estimated total funding amount listed is $2,900,000.
Is cost sharing or matching required?
No. The FOA states there is no cost sharing or matching requirement.
Which agency and institute are offering this grant?
The program is offered by the National Institutes of Health (NIH), specifically through the National Institute of Allergy and Infectious Diseases (NIAID).
What is the CFDA information associated with this opportunity?
The CFDA numbers listed are 93.855 (Allergy, Immunology and Transplantation Research) and 93.856 (Microbiology and Infectious Diseases Research).
What is the funding activity or main field of support?
The funding activity falls under health.
When was this opportunity posted?
It was posted on October 18, 2010.
What was the closing date for applications?
The original and current closing date listed is May 12, 2011.
When was the FOA archived?
The archive date listed is June 12, 2011.
Who is eligible to apply?
Eligibility is broad and includes many types of U.S. domestic organizations and governments (such as state, county, and city/township governments; special district governments; and independent school districts), public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (with or without 501(c)(3) status, other than institutions of higher education), and for-profit organizations (including small businesses and other than small businesses). Additional categories are also noted in the announcement.
Are non-U.S. (foreign) organizations eligible?
Yes. The FOA explicitly includes non-U.S. entities (foreign organizations) and regional organizations.
Are community-focused and underrepresented institution types included in eligibility?
Yes. The FOA explicitly includes institution types and entities such as Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).
Does the FOA suggest how partnerships might be structured?
The summary emphasizes durable partnerships and in-country sustainability. It also notes that strong applications could be led by U.S. institutions partnering abroad or by eligible foreign or regional organizations capable of hosting and sustaining center activities in-country.
Where can applicants find the official FOA announcement?
The official announcement is available on the NIH Grants Guide page at http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-11-001.html.
Who should be contacted for administrative help accessing or linking to the announcement?
Administrative help for accessing or linking to the announcement is routed through the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
What types of shared resources or platforms does the FOA imply could support a center?
The summary provides examples of shared platforms consistent with a center model, including clinical cohorts, vector surveillance systems, diagnostic laboratories, biostatistics and data management, and training and capacity-building activities.
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