Opportunity Information: Apply for RFA DK 11 031
Apply for RFA DK 11 031
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Type 1 Diabetes Mouse Resource (UC4)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on Oct 24, 2011 and posted on Oct 24, 2011.
- Applicants must submit their applications by Mar 14, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,500,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $300,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: City or township governments Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized) State governments Small businesses For profit organizations other than small businesses Independent school districts County governments Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Type 1 Diabetes Mouse Resource (T1DR) (UC4) funding opportunity, listed as RFA-DK-11-031, is a National Institutes of Health (NIH) cooperative agreement meant to support the continuation of a centralized mouse resource for the Type 1 Diabetes research community. The core purpose is to maintain an archive of valuable mouse strains and to distribute those strains broadly so investigators can access well-characterized models without having to recreate them independently. In the next phase described in the announcement, the program also adds a major emphasis on expanding access to more complex, specialized mouse strains that enable studies of human cells and tissues inside living animals, which is increasingly important for translational and human-relevant Type 1 Diabetes research.
The mechanism is a cooperative agreement (UC4), which typically indicates that NIH expects an active partnership with the awardee rather than a fully independent, investigator-directed grant. In practice, that usually means the funded resource operates as a community-facing infrastructure project with milestones, coordination, and ongoing interaction with NIH program staff to ensure the repository and distribution efforts align with field-wide priorities. Only one award was anticipated, highlighting that NIH intended to fund a single, centralized resource site rather than multiple competing repositories.
Financially, the opportunity listed an estimated total funding amount of $2,500,000, with an award ceiling of $300,000, and it did not require cost sharing or matching. The funding activity category is associated with diabetes and related health research under CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), reflecting the involvement of NIH institutes focused on these disease areas. The project is framed as a shared resource for the broader research ecosystem rather than a single-lab research study.
Eligibility was broad and included a wide range of domestic and international applicants. Eligible applicants covered various levels of government (state, county, city/township, special district), public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) nonprofits), and for-profit organizations (including small businesses and other for-profits). The announcement also explicitly included institutions serving specific populations (such as HBCUs, Hispanic-serving institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions), faith-based and community-based organizations, U.S. territories or possessions, and non-U.S. entities. In addition, foreign components, as defined by NIH policy, were allowed, indicating NIH was open to leveraging specialized expertise or infrastructure located outside the United States if it strengthened the resource.
Key dates show the FOA was posted on October 24, 2011, with an original and current closing date of March 14, 2012, and an archive date of April 14, 2012. The administering agency was NIH, and the public listing provided a link to the full FOA text and contact information through the NIH Office of Extramural Research (OER) for access or technical issues. Overall, the opportunity was designed to keep a high-value Type 1 Diabetes mouse repository operating for the field while also pushing the resource forward by increasing the availability of advanced mouse models suited for in vivo analysis of human biological materials.
Frequently Asked Questions (FAQs)
What is the Type 1 Diabetes Mouse Resource (T1DR) (UC4) funding opportunity?
It is an NIH cooperative agreement funding opportunity (UC4) intended to support the continuation of a centralized mouse resource for the Type 1 Diabetes research community. The opportunity is listed as RFA-DK-11-031.
What is the main purpose of this grant?
The core purpose is to maintain an archive of valuable mouse strains and distribute those strains broadly so investigators can access well-characterized models without having to recreate them independently. The next phase also emphasizes expanding access to more complex and specialized mouse strains that enable studies of human cells and tissues in vivo.
What kinds of activities is the funded resource expected to support?
Based on the description, the resource is expected to (1) maintain a centralized archive of valuable Type 1 Diabetes-related mouse strains, (2) distribute those strains broadly to the research community, and (3) expand access to advanced mouse strains designed to support in vivo studies of human cells and tissues for translational and human-relevant Type 1 Diabetes research.
What does it mean that this is a cooperative agreement (UC4) rather than a standard research grant?
A UC4 cooperative agreement typically indicates an active partnership between NIH and the awardee. In practice, this usually means the funded project operates as community-facing research infrastructure with coordination, milestones, and ongoing interaction with NIH program staff to ensure the repository and distribution activities align with field-wide priorities.
Is this opportunity intended to fund one site or multiple sites?
Only one award was anticipated, which signals NIH intended to support a single, centralized resource site rather than multiple competing repositories.
How much funding is available under this opportunity?
The listing provided an estimated total funding amount of $2,500,000 and an award ceiling of $300,000.
Is cost sharing or matching required?
No. The opportunity did not require cost sharing or matching.
Which federal agency administers this funding opportunity?
The administering agency is the National Institutes of Health (NIH).
What is the CFDA number associated with this opportunity?
The opportunity is associated with CFDA 93.847, described as Diabetes, Digestive, and Kidney Diseases Extramural Research.
What research area or program category does this opportunity fall under?
It is associated with diabetes and related health research and is framed as a shared resource for the broader research ecosystem rather than a single-lab research study.
Who is eligible to apply?
Eligibility was broad and included domestic and international applicants. Eligible applicants include: various levels of government (state, county, city/township, special district); public and private institutions of higher education; nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) nonprofits); and for-profit organizations (including small businesses and other for-profits).
Are minority-serving institutions and community-based organizations eligible?
Yes. The announcement explicitly included institutions serving specific populations (including HBCUs, Hispanic-serving institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions), as well as faith-based and community-based organizations.
Are U.S. territories or possessions eligible?
Yes. The eligibility description explicitly included U.S. territories or possessions.
Are non-U.S. entities eligible to apply?
Yes. The eligibility description included non-U.S. entities and also stated that foreign components (as defined by NIH policy) were allowed.
What does it mean that foreign components are allowed?
It means NIH was open to leveraging specialized expertise or infrastructure located outside the United States, if doing so would strengthen the mouse resource effort, consistent with NIH policy definitions for foreign components.
When was the funding opportunity posted?
The FOA was posted on October 24, 2011.
What was the application closing date?
The original and current closing date listed was March 14, 2012.
When was the FOA archived?
The archive date listed was April 14, 2012.
Where can applicants find the full FOA text and official details?
The public listing indicated a link to the full FOA text and included contact information through the NIH Office of Extramural Research (OER) for access or technical issues.
What is the program trying to add or expand in the next phase?
The next phase adds a major emphasis on expanding access to more complex, specialized mouse strains that enable studies of human cells and tissues inside living animals. This is described as increasingly important for translational and human-relevant Type 1 Diabetes research.
Is this funding meant for a single laboratory's research project?
No. The opportunity is described as a shared resource for the broader Type 1 Diabetes research community, focused on maintaining and distributing mouse strains and expanding access to advanced models, rather than supporting a single-lab, investigator-driven research study.
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Applicants who have applied for this opportunity (RFA DK 11 031) also looked into and applied for these:
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|---|
| Career Development Programs in Diabetes Research for Behavioral Scientists (K12) Apply for RFA DK 11 028 Funding Number: RFA DK 11 028 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Improving Adherence in Pre teens, Adolescents and Young Adults with Type 1 Diabetes (DP3) Apply for RFA DK 11 029 Funding Number: RFA DK 11 029 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $400,000 |
| Targeted Analyses of Jackson Heart Study Data (R01) Apply for RFA HL 13 007 Funding Number: RFA HL 13 007 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Bioengineering Interdisciplinary Training and Education for Type I Diabetes Research (T90/R90) Apply for RFA DK 11 023 Funding Number: RFA DK 11 023 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $250,000 |
| NIDDK Mentored Research Scientist Development Award (K01) Apply for PAR 12 020 Funding Number: PAR 12 020 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| NIDDK Education Program Grants (R25) Apply for PAR 12 047 Funding Number: PAR 12 047 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $100,000 |
| Prevention and Treatment of Obesity, Diabetes, and Chronic Kidney Disease in Military Populations (R01) Apply for PAR 12 048 Funding Number: PAR 12 048 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) (U01) Apply for RFA DK 11 026 Funding Number: RFA DK 11 026 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $250,000 |
| Planning Centers for Interdisciplinary Research in Benign Urology (IR BU) (P20) Apply for RFA DK 12 003 Funding Number: RFA DK 12 003 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $200,000 |
| Limited Competition for the Data Coordinating Center for Type 1 Diabetes TrialNet (UC4) Apply for RFA DK 12 503 Funding Number: RFA DK 12 503 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Limited Competition Continuation of the Clinical Islet Transplantation (CIT) Consortium Data Coordinating Center (U01) Apply for RFA DK 12 501 Funding Number: RFA DK 12 501 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Nutrition Obesity Research Centers (P30) Apply for RFA DK 12 004 Funding Number: RFA DK 12 004 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $750,000 |
| NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) Genetic Research Centers (GRCs) (U01) Apply for RFA DK 11 032 Funding Number: RFA DK 11 032 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $250,000 |
| Limited Competition for Data Coordinating Center (DCC) for NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) (U01) Apply for RFA DK 11 502 Funding Number: RFA DK 11 502 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $900,000 |
| The Collaborative Islet Transplantation Registry (UC4) Apply for RFA DK 12 002 Funding Number: RFA DK 12 002 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $530,000 |
| NIDDK Short Term Education Program for Underrepresented Persons (STEP UP) (R25) Apply for RFA DK 12 005 Funding Number: RFA DK 12 005 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $158,000 |
| The Human Islet Distribution Coordinating Center (UC4) Apply for RFA DK 12 001 Funding Number: RFA DK 12 001 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $2,000,000 |
| Secondary Analyses in Obesity, Diabetes and Digestive and Kidney Diseases (R21) Apply for PA 12 125 Funding Number: PA 12 125 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $200,000 |
| Pilot and Feasibility Clinical Research Grants in Diabetes, and Endocrine and Metabolic Diseases (R21) Apply for PA 12 157 Funding Number: PA 12 157 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $200,000 |
| Translational Research to Improve Obesity and Diabetes Outcomes (R18) Apply for PAR 12 172 Funding Number: PAR 12 172 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
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