Opportunity Information: Apply for RFA DK 15 030

  • The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Type 1 Diabetes Pathfinder Award (DP2)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.855 Allergy and Infectious Diseases Research 93.856 Microbiology and Infectious Diseases Research.
  • This funding opportunity was created on Jul 29, 2015 and posted on Jul 29, 2015.
  • Applicants must submit their applications by Feb 17, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $10,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $300,000.00 in funding.
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Public and State controlled institutions of higher education For profit organizations other than small businesses Small businesses Native American tribal governments (Federally recognized) Independent school districts County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education State governments Public housing authorities/Indian housing authorities.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:

The Type 1 Diabetes Pathfinder Award (DP2) is a National Institutes of Health (NIH) grant opportunity created to back a small number of unusually creative early stage investigators who want to take big, unconventional swings at important questions in type 1 diabetes (T1D) and its complications. Originally launched in 2008 under the Strategic Plan for Type 1 Diabetes Research, the program is meant to accelerate high-risk, high-reward ideas that could reshape how the field thinks about prevention, disease mechanisms, treatment, or long-term outcomes. A key point is that proposals do not have to sit neatly inside traditional biomedical or behavioral research lanes; the emphasis is on bold innovation, as long as the work is clearly relevant to T1D.

This award is positioned as a complement to the NIH R01 pathway rather than a replacement for it. NIH notes that R01 grants remain the main mechanism supporting early stage investigators, while the DP2 Pathfinder Award is specifically designed to give a limited number of investigators room to pursue unusually original approaches that might not fit typical incremental funding expectations. In practical terms, the program is looking for ideas with the potential to create major impact on broad, important problems related to T1D, including complications.

The funding opportunity is listed as RFA-DK-15-030 and was posted on July 29, 2015, with an application closing date of February 17, 2016 (and archived March 19, 2016). NIH anticipated making about 4 awards, with an estimated total funding amount of $10,000,000. The listed award ceiling is $300,000. The announcement sits within the broader health domain and is tied to multiple CFDA program areas: 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), 93.855 (Allergy and Infectious Diseases Research), and 93.856 (Microbiology and Infectious Diseases Research). There is no cost sharing or matching requirement.

Eligibility is broad across U.S.-based organizations and includes many types of public and private entities. Examples named in the notice include public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (with or without 501(c)(3) status, other than institutions of higher education), for-profit organizations (including small businesses and other for-profits), and a wide range of government entities (state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities). The opportunity also explicitly includes several institution types often highlighted for inclusion efforts, such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), along with faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions. At the same time, the announcement makes clear that foreign institutions are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed.

For applicants looking for the full official requirements, instructions, and any institute-specific details, NIH provided an announcement page (in the NIH grants guide) and general support contacts through the NIH Office of Extramural Research (OER) webmaster for access or linking issues.

Type 1 Diabetes Pathfinder Award (DP2) (RFA-DK-15-030) FAQs

1) What is the Type 1 Diabetes Pathfinder Award (DP2)?

The Type 1 Diabetes Pathfinder Award (DP2) is an NIH grant opportunity designed to support a small number of unusually creative early stage investigators pursuing bold, unconventional research ideas related to type 1 diabetes (T1D) and its complications.

2) What is the main goal of this DP2 program?

The program aims to accelerate high-risk, high-reward projects that could significantly reshape how the field thinks about T1D prevention, disease mechanisms, treatment, or long-term outcomes, including complications.

3) What kinds of research topics are considered relevant?

Projects must be clearly relevant to type 1 diabetes and/or its complications, and may address broad, important problems in areas such as prevention, disease mechanisms, treatment approaches, or long-term outcomes.

4) Does the proposed research need to fit within traditional biomedical or behavioral research categories?

No. A key point of the announcement is that proposals do not need to fit neatly into traditional biomedical or behavioral research lanes. The emphasis is on bold innovation, as long as the work is clearly relevant to T1D.

5) Who is this award intended to support?

The opportunity is intended to support early stage investigators who want to take big, unconventional swings at important questions in type 1 diabetes and its complications.

6) How does this award relate to the NIH R01 grant mechanism?

NIH positions the DP2 Pathfinder Award as a complement to the R01 pathway, not a replacement. NIH notes that R01 grants remain the main mechanism supporting early stage investigators, while DP2 provides room for unusually original approaches that may not fit incremental funding expectations.

7) What is the funding opportunity number (FOA) for this program?

The funding opportunity is listed as RFA-DK-15-030.

8) When was this opportunity posted, and when were applications due?

The notice was posted on July 29, 2015. The application closing date listed is February 17, 2016.

9) Is this funding opportunity still active?

No. The opportunity is described as archived on March 19, 2016.

10) How many awards did NIH expect to make?

NIH anticipated making about 4 awards.

11) What was the estimated total funding amount for the program?

The estimated total funding amount listed is $10,000,000.

12) What is the award ceiling?

The listed award ceiling is $300,000.

13) Is there a cost sharing or matching requirement?

No. The announcement states there is no cost sharing or matching requirement.

14) Which federal agency is offering this grant opportunity?

This is a National Institutes of Health (NIH) grant opportunity.

15) What broader research initiative did this program originate from?

The program was originally launched in 2008 under the Strategic Plan for Type 1 Diabetes Research.

16) What CFDA program areas are associated with this announcement?

The announcement is tied to multiple CFDA program areas: 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), 93.855 (Allergy and Infectious Diseases Research), and 93.856 (Microbiology and Infectious Diseases Research).

17) What types of organizations are eligible to apply?

Eligibility is broad across U.S.-based organizations and includes public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (with or without 501(c)(3) status, other than institutions of higher education), for-profit organizations (including small businesses and other for-profits), and many government entities.

18) What government entities are included as eligible applicants?

The notice lists state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities as eligible examples.

19) Are specific institution types highlighted for inclusion efforts eligible?

Yes. The opportunity explicitly includes Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs).

20) Are faith-based or community-based organizations eligible?

Yes. Faith-based or community-based organizations are explicitly included as eligible in the notice.

21) Are U.S. territories or possessions eligible?

Yes. The notice includes U.S. territories or possessions among eligible applicants.

22) Are foreign institutions eligible to apply?

No. The announcement makes clear that foreign institutions are not eligible to apply.

23) Are non-U.S. components of U.S. organizations allowed?

No. Non-U.S. components of U.S. organizations are not eligible.

24) Are foreign components (as defined by NIH policy) allowed?

No. The announcement states that foreign components (as defined by NIH policy) are not allowed.

25) Where can applicants find the official requirements and application instructions?

NIH provided an announcement page in the NIH grants guide for full official requirements, instructions, and any institute-specific details.

26) Who should be contacted for access or linking issues related to the official announcement page?

The notice references general support contacts through the NIH Office of Extramural Research (OER) webmaster for access or linking issues.

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