Opportunity Information: Apply for EPA G2009 STAR E2
Apply for EPA G2009 STAR E2
- The Environmental Protection Agency in the environment sector is offering a public funding opportunity titled "Understanding the Role of Nonchemical Stressors and Developing Analytic Methods for Cumulative Risk Assessments" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 66.509 Science To Achieve Results (STAR) Research Program.
- This funding opportunity was created on Feb 18, 2009 and posted on Feb 18, 2009.
- Applicants must submit their applications by Jun 17, 2009 Please refer to the full announcement, including Section IV for additional information on submission methods and due dates.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $8,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $1,250,000.00 in funding.
- The number of recipients for this funding is limited to 9 candidate(s).
- Eligible applicants include: Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education County governments City or township governments State governments.
- See Section III of the announcement for additional eligibility information.
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Opportunity Summary:
The Environmental Protection Agency (EPA) announced this funding opportunity under its Science to Achieve Results (STAR) research program to strengthen the science behind cumulative risk assessment. The central idea is that real-world health risks rarely come from a single pollutant or a single exposure pathway. Instead, people and communities often face mixtures of chemical exposures (like air pollutants, metals, pesticides, or industrial contaminants) alongside nonchemical stressors (such as psychosocial stress, poverty-related conditions, limited access to health care, noise, poor housing, or other community-level pressures). EPA is looking for research that helps account for these combined and interacting influences so that cumulative risk assessments better reflect actual conditions, including differences across populations and neighborhoods.
The opportunity targets two closely related research gaps that currently make cumulative risk assessment difficult. One focus area (labeled STAR E1 in the announcement) is the development of statistical and other analytic methods that can combine and analyze disparate types of data. In practice, cumulative risk work often has to integrate information that does not naturally fit together, such as environmental monitoring data, biomonitoring, health outcome records, census and socioeconomic indicators, stress and mental health measures, land-use information, and multi-route exposure estimates. EPA is encouraging applicants to create or improve methods that can reconcile different data scales and formats, handle missing or uncertain data, and support robust inference when studying multiple stressors at once. The aim is not just to produce a single case study, but to advance tools and approaches that other researchers and decision-makers can use in future cumulative risk assessments.
The second focus area (STAR E2) emphasizes understanding how chemical and nonchemical stressors jointly affect health outcomes. This part of the solicitation is about the science of combined effects: whether nonchemical stressors amplify, modify, or otherwise interact with chemical exposures to change risk. For example, chronic stress or limited resources can influence susceptibility through physiological pathways, influence exposure patterns through housing or occupational factors, and affect the ability to avoid or mitigate exposures. EPA is seeking research that evaluates these combined effects in a rigorous way, with attention to mechanisms, exposure patterns across multiple routes (inhalation, ingestion, dermal), and community factors that change exposure or toxicity. The underlying objective is to move cumulative risk assessment beyond simply adding up individual risks and toward approaches that can reflect real interactions and differential vulnerability.
This is a discretionary funding opportunity offered as grants and/or cooperative agreements, with an estimated total funding level of about $8,000,000 and an expected nine awards. Individual awards can be as large as $1,250,000, and there is no cost-sharing or matching requirement stated for applicants. Eligible applicants include a wide range of organizations, notably public and state-controlled and private institutions of higher education, federally recognized Native American tribal governments, and various levels of government (state, county, city, or township), with additional eligibility details referenced in the full announcement. The funding is cataloged under CFDA 66.509, the STAR Research Program.
Key administrative dates in the posted notice include a posting date of February 18, 2009, and an application closing date of June 17, 2009, with the opportunity archived on July 17, 2009. Applicants were directed to consult the full solicitation (especially Section IV) for the specific submission instructions and deadline details. For access issues or technical questions, the notice lists Deborah Segal at EPA as the technical contact, including a phone number (202-343-9797). Overall, the opportunity is structured to push the field toward more realistic, decision-relevant cumulative risk assessments by funding interdisciplinary teams that can both build better analytic methods and generate stronger evidence on how nonchemical and chemical stressors combine to influence health.
Frequently Asked Questions (FAQs)
What is this EPA funding opportunity about?
This opportunity is an EPA Science to Achieve Results (STAR) research program solicitation focused on strengthening the science behind cumulative risk assessment. The premise is that real-world health risks typically involve multiple chemical exposures (for example, air pollutants, metals, pesticides, or industrial contaminants) alongside nonchemical stressors (such as psychosocial stress, poverty-related conditions, limited access to health care, noise, poor housing, or other community-level pressures). EPA is seeking research that helps cumulative risk assessments better represent these combined, interacting influences and reflect differences across populations and neighborhoods.
What does EPA mean by "cumulative risk assessment" in this announcement?
In this announcement, cumulative risk assessment refers to approaches that evaluate health risks arising from mixtures of chemical exposures and nonchemical stressors, potentially across multiple exposure pathways and routes, rather than evaluating a single pollutant or a single pathway in isolation.
What are the main research focus areas?
The solicitation identifies two closely related focus areas:
- STAR E1: Development of statistical and other analytic methods to combine and analyze disparate data types used in cumulative risk work.
- STAR E2: Research to understand how chemical and nonchemical stressors jointly affect health outcomes, including interactions and differential vulnerability.
What kinds of projects fit under Focus Area STAR E1?
STAR E1 is centered on methods development. EPA is encouraging applicants to create or improve statistical and analytic approaches that can integrate data that do not naturally align, such as environmental monitoring, biomonitoring, health outcome records, census and socioeconomic indicators, stress and mental health measures, land-use information, and multi-route exposure estimates. The announcement highlights needs such as reconciling different data scales and formats, handling missing or uncertain data, and supporting robust inference when evaluating multiple stressors together.
Is EPA looking for a single case study or broader tools?
The stated aim under STAR E1 is not only to produce a single case study, but to advance tools and approaches that other researchers and decision-makers can use in future cumulative risk assessments.
What kinds of projects fit under Focus Area STAR E2?
STAR E2 focuses on the science of combined effects: how chemical and nonchemical stressors together influence health outcomes. EPA is looking for research that evaluates whether nonchemical stressors amplify, modify, or otherwise interact with chemical exposures to change risk, with attention to mechanisms, exposure patterns across multiple routes (inhalation, ingestion, dermal), and community factors that can change exposure or toxicity.
What are examples of nonchemical stressors mentioned in the announcement?
The notice gives examples including psychosocial stress, poverty-related conditions, limited access to health care, noise, poor housing, and other community-level pressures.
What are examples of chemical exposures mentioned in the announcement?
Examples listed include air pollutants, metals, pesticides, and industrial contaminants.
Why is EPA emphasizing chemical and nonchemical stressors together?
The announcement explains that cumulative risk assessment is difficult when methods and evidence do not adequately account for combined and interacting influences. EPA wants to move beyond simply adding up individual risks and toward approaches that can reflect real interactions and differential vulnerability across communities and populations.
What types of data does EPA expect applicants to integrate or analyze?
The opportunity description specifically references integrating and analyzing disparate data sources such as environmental monitoring data, biomonitoring, health outcome records, census and socioeconomic indicators, stress and mental health measures, land-use information, and multi-route exposure estimates.
What funding mechanism is being used?
This is a discretionary funding opportunity offered as grants and/or cooperative agreements.
How much total funding is expected to be available?
The estimated total funding level is about $8,000,000.
How many awards does EPA expect to make?
The notice indicates an expected nine awards.
What is the maximum award amount?
Individual awards can be as large as $1,250,000.
Is cost sharing or matching required?
No cost-sharing or matching requirement is stated in the information provided.
Who is eligible to apply based on the notice?
Eligible applicants include a range of organizations, including public and state-controlled and private institutions of higher education, federally recognized Native American tribal governments, and various levels of government (state, county, city, or township). The notice also references additional eligibility details in the full announcement.
What is the CFDA number for this opportunity?
The funding is cataloged under CFDA 66.509, the STAR Research Program.
What are the key dates listed in the posted notice?
- Posting date: February 18, 2009
- Application closing date: June 17, 2009
- Archive date: July 17, 2009
Where should applicants look for submission instructions and deadline details?
Applicants were directed to consult the full solicitation, especially Section IV, for specific submission instructions and detailed deadline information.
Who is the technical contact for access issues or technical questions?
The notice lists Deborah Segal at EPA as the technical contact, with phone number (202) 343-9797.
What is the overall goal of the solicitation?
Overall, EPA structured this opportunity to push cumulative risk assessment toward more realistic, decision-relevant practice by funding interdisciplinary research that both improves analytic methods (STAR E1) and strengthens evidence on how chemical and nonchemical stressors combine to influence health (STAR E2), including differences across populations and neighborhoods.
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