Opportunity Information: Apply for RFA DK 15 005
Apply for RFA DK 15 005
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Urinary Stone Disease Research Network Scientific Data Research Center (USDRN SDRC) (Collaborative U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on Aug 24, 2015 and posted on Aug 24, 2015.
- Applicants must submit their applications by Nov 18, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $4,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $700,000.00 in funding.
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Small businesses State governments Special district governments Native American tribal governments (Federally recognized) Independent school districts County governments Public housing authorities/Indian housing authorities Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Urinary Stone Disease Research Network Scientific Data Research Center (USDRN SDRC) (Collaborative U01) grant opportunity (Funding Opportunity Number RFA-DK-15-005) is a National Institutes of Health (NIH) cooperative agreement designed to build the data and coordinating backbone for a larger, multi-center research effort focused on urinary stone disease. The central goal is to establish a multi-center, multi-disciplinary network of investigators called the Urinary Stone Disease Research Network (USDRN). This announcement specifically funds the Scientific Data Research Center (SDRC), while a companion announcement released in parallel supports the USDRN Clinical Centers (CCs) under RFA-DK-15-004. In practice, the SDRC is meant to serve as the coordinating hub that supports and integrates the work of the clinical sites so the network can run large, consistent studies and produce high-quality, reusable research resources.
From a scientific standpoint, the USDRN is organized around three major activities. First, the network will design and conduct a randomized clinical trial that tests whether increasing fluid intake and urine output reduces the recurrence rate of urinary stones, and it is explicitly intended to include both adults and children. Second, the network will carry out clinical research aimed at better understanding ureteral stent-related pain and urinary symptoms, with an emphasis on identifying approaches that mitigate these problems for patients. Third, the network will generate a lasting resource for the broader scientific community by providing access to study data and by collecting biological samples during the research, creating a repository that can support future investigations beyond the original trial questions.
Because this is a cooperative agreement (U01), the funding structure signals substantial NIH scientific or programmatic involvement during the project period compared with a standard research grant. The SDRC awardees would typically be expected to coordinate with NIH and with the funded Clinical Centers to ensure shared protocols, consistent data collection, strong quality control, and efficient study operations across multiple sites. While the announcement text provided does not list detailed SDRC duties, the intent is clear: the SDRC is the infrastructure component that enables the network to function as a single, harmonized program rather than a set of disconnected studies.
The opportunity was posted on August 24, 2015, with an original and current closing date of November 18, 2015, and it was archived on December 19, 2015. NIH anticipated making about two awards under this FOA. The estimated total funding amount listed is $4,000,000, and the award ceiling is $700,000. The program is associated with CFDA number 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), aligning it with NIH activities in kidney and urologic health research. No cost sharing or matching requirement is indicated.
Eligibility is broad and includes many common applicant categories, spanning public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations other than small businesses, small businesses, state and local governmental entities, tribal governments and tribal organizations, public housing authorities/Indian housing authorities, independent school districts, and additional categories noted in the announcement. The eligibility list also explicitly includes a range of institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, Asian American and Native American Pacific Islander-serving institutions, faith-based and community-based organizations, U.S. territories or possessions, and even non-U.S. entities (foreign organizations) and regional organizations, reflecting NIH's broad approach to permitting capable organizations to participate.
For applicants or interested parties seeking the official announcement and full requirements, NIH provided an additional information link to the NIH grants guide page for RFA-DK-15-005. For technical issues accessing the announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
FAQs: Urinary Stone Disease Research Network Scientific Data Research Center (USDRN SDRC) (Collaborative U01) - RFA-DK-15-005
What is this grant opportunity?
This is an NIH cooperative agreement (U01) funding opportunity to support the Scientific Data Research Center (SDRC) for the Urinary Stone Disease Research Network (USDRN). The SDRC is intended to provide the data and coordinating backbone for a larger multi-center research effort in urinary stone disease.
What is the Funding Opportunity Number (FOA)?
The Funding Opportunity Number is RFA-DK-15-005.
What does "Collaborative U01" mean in this context?
It indicates a cooperative agreement mechanism where NIH expects substantial scientific and/or programmatic involvement during the project period compared with a standard research grant. The SDRC is expected to work closely with NIH and with the funded Clinical Centers so the network operates as a coordinated program.
What is the USDRN?
The USDRN (Urinary Stone Disease Research Network) is a planned multi-center, multi-disciplinary network of investigators focused on urinary stone disease. The overall aim is to run large, consistent studies across multiple sites and to produce high-quality, reusable research resources.
What is the SDRC and what is its role?
The SDRC (Scientific Data Research Center) is intended to function as the coordinating hub that supports and integrates the work of the clinical sites. While the provided text does not list detailed SDRC duties, the stated intent is that the SDRC enables shared protocols, consistent data collection, strong quality control, and efficient multi-site study operations.
Is there a related or companion funding announcement for other parts of the network?
Yes. A companion announcement released in parallel supports the USDRN Clinical Centers (CCs) under RFA-DK-15-004. This announcement (RFA-DK-15-005) specifically funds the SDRC.
What major research activities will the USDRN conduct?
The network is organized around three major activities:
- Designing and conducting a randomized clinical trial testing whether increasing fluid intake and urine output reduces urinary stone recurrence, explicitly intended to include both adults and children.
- Conducting clinical research to better understand ureteral stent-related pain and urinary symptoms, including identifying approaches to mitigate these patient problems.
- Creating a lasting community resource by providing access to study data and collecting biological samples during research to build a repository that can support future investigations.
Does the randomized clinical trial include both adults and children?
Yes. The trial is explicitly intended to include both adults and children.
What clinical issue besides stone recurrence is explicitly included in the research plan?
The network will also study ureteral stent-related pain and urinary symptoms, with an emphasis on identifying approaches that reduce or mitigate these problems for patients.
Will the network create a data and biospecimen resource for future research?
Yes. A stated goal is to generate a lasting resource by providing access to study data and collecting biological samples during the research, creating a repository to support future investigations beyond the original trial questions.
Which agency is offering this opportunity?
The opportunity is offered by the National Institutes of Health (NIH).
What is the CFDA number associated with this program?
The CFDA number listed is 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research).
How much total funding is anticipated under this FOA?
The estimated total funding amount listed is $4,000,000.
What is the award ceiling?
The award ceiling is $700,000.
How many awards did NIH anticipate making?
NIH anticipated making about two awards under this FOA.
Is cost sharing or matching required?
No cost sharing or matching requirement is indicated in the provided information.
When was the opportunity posted?
The opportunity was posted on August 24, 2015.
What was the closing date for applications?
The original and current closing date listed is November 18, 2015.
Is this funding opportunity still active?
No. It was archived on December 19, 2015.
Who is eligible to apply?
Eligibility is broad and includes many applicant categories, including:
- Public and private institutions of higher education
- Nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) entities)
- For-profit organizations other than small businesses
- Small businesses
- State and local governmental entities
- Tribal governments and tribal organizations
- Public housing authorities/Indian housing authorities
- Independent school districts
- Other categories noted in the announcement
Are minority-serving institutions and community-based organizations included in the eligibility list?
Yes. The eligibility list explicitly includes categories such as HBCUs, Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian-serving institutions, Asian American and Native American Pacific Islander-serving institutions, as well as faith-based and community-based organizations.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are explicitly included in the eligibility list described.
Are non-U.S. (foreign) organizations eligible?
Yes. The eligibility list explicitly includes non-U.S. entities (foreign organizations) and regional organizations.
Where can applicants find the official announcement and full requirements?
NIH provided an additional information link to the NIH grants guide page for RFA-DK-15-005, which is the official source for the full announcement and requirements.
Who should be contacted for technical issues accessing the announcement?
For technical issues accessing the announcement, the listed contact is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
How does the SDRC relate to the Clinical Centers (CCs) in practice?
The SDRC is intended to serve as the coordinating hub supporting and integrating the work of the clinical sites, so the network can run large, consistent studies with shared protocols, consistent data collection, strong quality control, and efficient study operations across multiple sites.
What is the overarching purpose of funding the SDRC specifically?
The stated purpose is to build the data and coordinating backbone that enables the USDRN to function as a harmonized, multi-center program and to produce high-quality, reusable research resources for the broader scientific community.
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| Funding Opportunity |
|---|
| Urinary Stone Disease Research Network Clinical Centers (USDRN CCs) (Collaborative U01) Apply for RFA DK 15 004 Funding Number: RFA DK 15 004 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $450,000 |
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