Opportunity Information: Apply for PAR 11 099

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "U.S. India Bilateral Brain Research Collaborative Partnerships (U.S. India BRCP) (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.279 Drug Abuse and Addiction Research Programs 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders.
  • This funding opportunity was created on Jan 14, 2011 and posted on Jan 14, 2011.
  • Applicants must submit their applications by Mar 22, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Native American tribal governments (Federally recognized) For profit organizations other than small businesses Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments County governments Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Special district governments Private institutions of higher education Public housing authorities/Indian housing authorities.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The U.S.-India Bilateral Brain Research Collaborative Partnerships (U.S.-India BRCP) (R21) opportunity (Funding Opportunity Number PAR-11-099) was a discretionary NIH grant program designed to spark and strengthen joint neuroscience research partnerships between investigators in the United States and India. It was issued collaboratively by three NIH Institutes in the U.S. Department of Health and Human Services (the National Institute of Neurological Disorders and Stroke, the National Institute of Mental Health, and the National Institute on Drug Abuse) together with India s Department of Biotechnology under the Ministry of Science and Technology. The central aim was to encourage truly bilateral work that combines expertise, patient populations, tools, and research capacity across both countries to advance understanding, treatment, and ultimately cures for neurological disorders, mental health conditions, and addictive disorders.

As an R21 mechanism, this program was oriented toward exploratory and developmental projects, meaning it was intended to support early stage, high impact ideas, pilot studies, proof of concept work, and new collaborative directions rather than large, long term programs. The emphasis was not just on producing scientific findings, but also on building the collaborative scaffolding needed for sustained partnership, such as shared methods, harmonized protocols, and coordinated research plans that can grow into larger efforts later.

The research scope was intentionally broad within neuroscience and brain health, with priority areas including studies that investigate mechanisms underlying neurological, mental, and addictive disorders and diseases. The announcement also explicitly welcomed planning activities for population based research and clinical trials, which signals support for groundwork like feasibility assessments, recruitment strategies, protocol development, and coordination approaches that are often necessary before launching full scale trials or epidemiologic studies. Another major focus area was infrastructure development for resource, tool, and data sharing. In practical terms, that could include creating shared databases, biorepositories, standardized data elements, common analytical pipelines, or collaborative platforms that allow U.S. and Indian teams to exchange and jointly analyze data, specimens, and tools. The program also highlighted advancing global health research, especially where the proposed work aligns with the missions of the participating NIH Institutes and Indias DBT, reinforcing that projects should have clear relevance to major brain related health burdens and translational potential.

From an administrative standpoint, the program was categorized under Education and Health funding activities and mapped to CFDA numbers tied to mental health research (93.242), drug abuse and addiction research (93.279), and extramural neuroscience and neurological disorders research (93.853). The award ceiling listed in the source data was 200,000, and there was no cost sharing or matching requirement, so applicants were not expected to provide institutional matching funds as a condition of eligibility.

Eligibility was broad and included many types of U.S. applicant organizations, spanning public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status, with the usual exclusions and conditions noted in NIH policies), for profit organizations other than small businesses, small businesses, and multiple layers of government entities (state, county, city or township, special district governments). It also included Native American tribal governments (both federally recognized and other than federally recognized), and public housing authorities/Indian housing authorities. The eligibility clarification further named a range of mission focused institution types and community anchored entities, such as Historically Black Colleges and Universities, Hispanic Serving Institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, faith based or community based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. While the listing describes eligible applicant types on the U.S. side, the scientific intent of the FOA was explicitly bilateral, meaning proposals were expected to involve substantive collaboration between U.S. and Indian investigators rather than parallel, loosely connected projects.

Key timing details in the source record show it was posted and created on January 14, 2011, with an original and current closing date of March 22, 2011, and an archive date of April 22, 2011, indicating this was a time limited call in that period. The official announcement was hosted through the NIH Grants Guide (link provided in the record), and the contact point for access or linking issues was the NIH Office of Extramural Research webmaster (FBOWebmaster@OD.NIH.GOV).

In plain terms, this grant opportunity was a targeted U.S.-India call to seed new joint neuroscience collaborations and accelerate shared progress on brain related disorders by funding exploratory R21 projects, planning efforts for larger population and clinical studies, and the practical infrastructure needed to share data and research resources across borders.

Frequently Asked Questions (FAQs)

What is the U.S.-India Bilateral Brain Research Collaborative Partnerships (U.S.-India BRCP) (R21) opportunity?

It was a discretionary NIH grant program intended to spark and strengthen joint neuroscience research partnerships between investigators in the United States and India through exploratory/developmental R21 projects.

What is the Funding Opportunity Number (FON) for this program?

The Funding Opportunity Number was PAR-11-099.

What type of NIH grant mechanism was used?

This opportunity used the NIH R21 mechanism, which is geared toward exploratory and developmental research.

What was the central aim of the program?

The central aim was to encourage truly bilateral work that combines expertise, patient populations, tools, and research capacity across the U.S. and India to advance understanding, treatment, and ultimately cures for neurological disorders, mental health conditions, and addictive disorders.

Which organizations issued this opportunity collaboratively?

It was issued collaboratively by three NIH Institutes (National Institute of Neurological Disorders and Stroke, National Institute of Mental Health, and National Institute on Drug Abuse) together with India s Department of Biotechnology (DBT) under the Ministry of Science and Technology.

What research areas were in scope?

The scope was broad within neuroscience and brain health, with priority areas including studies that investigate mechanisms underlying neurological, mental, and addictive disorders and diseases.

Did the announcement support planning activities for population-based research and clinical trials?

Yes. The announcement explicitly welcomed planning activities for population-based research and clinical trials, including groundwork such as feasibility assessments, recruitment strategies, protocol development, and coordination approaches.

Was infrastructure development an allowable or encouraged focus?

Yes. A major focus area was infrastructure development for resource, tool, and data sharing, such as shared databases, biorepositories, standardized data elements, common analytical pipelines, or collaborative platforms enabling exchange and joint analysis of data, specimens, and tools.

Was this program intended for large, long-term research programs?

No. As an R21 opportunity, it was oriented toward early-stage, high-impact ideas, pilot studies, proof-of-concept work, and new collaborative directions rather than large, long-term programs.

Beyond scientific findings, what else did the program emphasize?

It emphasized building collaborative scaffolding for sustained partnership, including shared methods, harmonized protocols, and coordinated research plans that could grow into larger efforts later.

How did the opportunity frame global health relevance?

It highlighted advancing global health research where the work aligns with the missions of the participating NIH Institutes and India s DBT, reinforcing relevance to major brain-related health burdens and translational potential.

What funding activity categories was this program associated with?

It was categorized under Education and Health funding activities.

What CFDA numbers were associated with this opportunity?

The program was mapped to CFDA numbers 93.242 (mental health research), 93.279 (drug abuse and addiction research), and 93.853 (extramural neuroscience and neurological disorders research).

What was the award ceiling listed in the source data?

The award ceiling listed was 200,000.

Was cost sharing or matching required?

No. There was no cost sharing or matching requirement, meaning applicants were not expected to provide institutional matching funds as a condition of eligibility.

Who was eligible to apply on the U.S. side (types of organizations)?

Eligibility included a wide range of U.S. organization types, including public and private institutions of higher education; nonprofit organizations (including those with and without 501(c)(3) status, subject to NIH policies); for-profit organizations other than small businesses; small businesses; and multiple levels of government entities (state, county, city or township, special district governments).

Were tribal governments and housing authorities included as eligible applicants?

Yes. Eligibility included Native American tribal governments (both federally recognized and other than federally recognized) and public housing authorities/Indian housing authorities.

Did the eligibility listing include mission-focused institutions and community-anchored entities?

Yes. The eligibility clarification named institution types such as Historically Black Colleges and Universities, Hispanic Serving Institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions.

Did proposals need to be bilateral (U.S. and India) in nature?

Yes. While the listing described eligible U.S. applicant types, the stated scientific intent was explicitly bilateral, meaning proposals were expected to involve substantive collaboration between U.S. and Indian investigators rather than parallel, loosely connected projects.

When was this opportunity posted and created?

The source record shows it was posted and created on January 14, 2011.

What were the closing date and archive date?

The original and current closing date were March 22, 2011, and the archive date was April 22, 2011, indicating the call was time-limited during that period.

Where was the official announcement hosted?

The official announcement was hosted through the NIH Grants Guide (a link was provided in the source record).

Who was the contact for access or linking issues?

The contact point listed for access or linking issues was the NIH Office of Extramural Research webmaster at FBOWebmaster@OD.NIH.GOV.

In plain terms, what kinds of projects was this call trying to seed?

It was a targeted U.S.-India call to seed new joint neuroscience collaborations by funding exploratory R21 projects, planning efforts for larger population and clinical studies, and practical infrastructure needed to share data and research resources across borders.

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