Opportunity Information: Apply for PA 11 048
Apply for PA 11 048
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Women and Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Dec 12, 2013 and posted on Nov 30, 2010.
- Applicants must submit their applications by Dec 12, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: County governments State governments For profit organizations other than small businesses Independent school districts City or township governments Small businesses Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Women and Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R21) funding opportunity (PA-11-048) is a National Institutes of Health (NIH) research grant announcement led jointly by the National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA). Its central aim is to push forward exploratory and developmental research that clarifies how biological sex and sex/gender-related factors shape the initiation, escalation, patterns, and outcomes of drug and alcohol abuse and dependence. The announcement places special emphasis on understanding factors that are unique to women, while also encouraging direct comparisons between males and females to explain differences in vulnerability, course of illness, and response to interventions. The FOA explicitly welcomes both human studies and animal model research, reflecting an interest in findings that span from basic mechanisms to clinically relevant questions.
This opportunity uses the NIH R21 mechanism, which is typically designed to support early-stage, high-impact, and potentially higher-risk projects that can generate new hypotheses, preliminary data, or proof-of-concept evidence. The award ceiling listed is $200,000, and there is no cost sharing or matching requirement, meaning applicants are not required to provide non-federal funds to receive an award. The activity category is listed under education and health, and the associated CFDA programs are 93.273 (Alcohol Research Programs) and 93.279 (Drug Abuse and Addiction Research Programs), signaling that proposals may align with alcohol-focused questions, drug-focused questions, or the overlap between them as long as they are responsive to the core topic of sex/gender differences and women-specific factors.
A wide range of organizations are eligible to apply. Eligibility includes public and state-controlled institutions of higher education and private institutions of higher education, as well as nonprofit organizations (including those with and without 501(c)(3) status, except where otherwise restricted), for-profit organizations (including small businesses and other than small businesses), and multiple levels of government such as state governments, county governments, city or township governments, special district governments, and independent school districts. The FOA also allows applications from Native American tribal governments (both federally recognized and other than federally recognized) and tribal organizations, along with public housing authorities/Indian housing authorities. Additional eligible applicants called out include Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, U.S. territories or possessions, eligible federal agencies, and non-U.S. entities (foreign organizations). In practical terms, the eligibility language is broad and designed to encourage participation from diverse research settings, including community and population-focused organizations that may have access to relevant groups of participants or specialized data sources.
Key logistics and timing details in the source record indicate that the opportunity was posted on November 30, 2010, with an original closing date of January 7, 2014. The record shows a current closing date of December 12, 2013, and an archive date of January 12, 2014, meaning it is an older, archived announcement rather than an active one. For the complete and authoritative announcement text, NIH points applicants to the official FOA page at http://grants.nih.gov/grants/guide/pa-files/PA-11-048.html. For access or linking issues, the contact provided is the NIH Office of Extramural Research (OER) Webmaster (FBOWebmaster@OD.NIH.GOV), which is a technical contact rather than a scientific/program contact for research questions.
Overall, PA-11-048 is best understood as an NIH exploratory grant opportunity intended to spark and support innovative research that explains why and how drug and alcohol abuse/dependence differ by sex and by sex/gender-related influences, with deliberate attention to women-specific biological, behavioral, and contextual factors. By allowing both clinical/human and preclinical/animal-model approaches and by opening eligibility to a very broad set of institutions, the FOA signals a strong interest in building a multi-level evidence base that can ultimately inform prevention strategies, tailored interventions, and improved outcomes for substance use disorders across sexes and genders.
Frequently Asked Questions (FAQs)
What is the title of this funding opportunity?
The opportunity is titled Women and Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R21), funding opportunity number PA-11-048.
Which federal agencies and institutes lead this opportunity?
This is a National Institutes of Health (NIH) research grant announcement led jointly by the National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA).
What is the main purpose of PA-11-048?
The central aim is to support exploratory and developmental research that clarifies how biological sex and sex/gender-related factors influence the initiation, escalation, patterns, and outcomes of drug and alcohol abuse and dependence.
Does the announcement focus specifically on women?
Yes. The announcement places special emphasis on understanding factors that are unique to women, while also encouraging research that directly compares males and females to explain differences in vulnerability, course of illness, and response to interventions.
Are both human and animal studies allowed?
Yes. The FOA explicitly welcomes both human studies and animal model research, reflecting interest in work spanning basic mechanisms through clinically relevant questions.
What NIH funding mechanism is used for this opportunity?
This opportunity uses the NIH R21 mechanism, which is typically intended for exploratory and developmental projects, including early-stage, high-impact, and potentially higher-risk studies that can generate new hypotheses, preliminary data, or proof-of-concept evidence.
What is the maximum award amount listed?
The award ceiling listed is $200,000.
Is cost sharing or matching required?
No. There is no cost sharing or matching requirement. Applicants are not required to provide non-federal funds to receive an award.
What topic areas or program areas does this opportunity align with?
The activity category is listed under education and health, and the associated CFDA programs are 93.273 (Alcohol Research Programs) and 93.279 (Drug Abuse and Addiction Research Programs). Proposals may be alcohol-focused, drug-focused, or address the overlap between them, as long as they are responsive to the core topic of sex/gender differences and women-specific factors in substance use disorders.
What types of organizations are eligible to apply?
Eligibility is broad and includes:
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Nonprofit organizations (including those with and without 501(c)(3) status, except where otherwise restricted)
- For-profit organizations (including small businesses and other than small businesses)
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Native American tribal governments (federally recognized and other than federally recognized)
- Tribal organizations
- Public housing authorities/Indian housing authorities
- U.S. territories or possessions
- Eligible federal agencies
- Non-U.S. entities (foreign organizations)
Are specific institution types (such as HBCUs or Hispanic-serving institutions) explicitly included?
Yes. Additional eligible applicants specifically called out include Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), as well as faith-based or community-based organizations and regional organizations.
Can community-based organizations apply?
Yes. The eligibility language explicitly includes faith-based or community-based organizations, indicating that community and population-focused groups may apply if their proposed work fits the FOA focus.
Are for-profit entities eligible?
Yes. For-profit organizations are included, including both small businesses and other than small businesses.
Are foreign (non-U.S.) organizations eligible?
Yes. The FOA allows applications from non-U.S. entities (foreign organizations).
When was this opportunity posted?
The source record indicates the opportunity was posted on November 30, 2010.
What are the closing and archive dates shown in the record?
The record shows an original closing date of January 7, 2014, a current closing date of December 12, 2013, and an archive date of January 12, 2014.
Is PA-11-048 still active?
Based on the dates provided (including the archive date), this appears to be an older, archived announcement rather than an active funding opportunity.
Where can applicants find the official FOA text?
NIH points applicants to the official FOA page here: http://grants.nih.gov/grants/guide/pa-files/PA-11-048.html.
Who is the listed contact, and what is that contact for?
The contact provided is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV. This is described as a technical contact for access or linking issues, not a scientific or program contact for research questions.
What kinds of research outcomes does NIH appear to be seeking through this FOA?
The announcement is intended to spark innovative research that explains why and how substance use disorders differ by sex and sex/gender-related influences, with deliberate attention to women-specific biological, behavioral, and contextual factors. The broader intent is to help build evidence that can inform prevention strategies, tailored interventions, and improved outcomes across sexes and genders.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 11 048) also looked into and applied for these:
| Funding Opportunity |
|---|
| Women and Sex/Gender Differences in Drug and Alcohol Abuse/Dependence (R03) Apply for PA 11 049 Funding Number: PA 11 049 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Limited Competition Extramural Research Facilities Improvement Program (C06) Apply for RFA RR 11 001 Funding Number: RFA RR 11 001 Agency: National Institutes of Health Category: Education Health Funding Amount: $1,500,000 |
| Diversity promoting Institutions Drug Abuse Research Program (DIDARP) (R24) Apply for PAR 11 060 Funding Number: PAR 11 060 Agency: National Institutes of Health Category: Education Health Funding Amount: $350,000 |
| Advanced In Vivo Imaging to Understand Cancer Systems (R01) Apply for RFA CA 11 005 Funding Number: RFA CA 11 005 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Mitochondria in Cancer Epidemiology, Detection, Diagnosis and Prognosis (R01) Apply for PA 11 073 Funding Number: PA 11 073 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Mitochondria in Cancer Epidemiology, Detection, Diagnosis and Prognosis (R21) Apply for PA 11 074 Funding Number: PA 11 074 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Cancer Prevention Research Small Grant Program (R03) Apply for PAR 11 079 Funding Number: PAR 11 079 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Shared Instrumentation Grant Program (S10) Apply for PAR 11 081 Funding Number: PAR 11 081 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| NLM Grants for Scholarly Works in Biomedicine and Health (G13) Apply for PAR 11 084 Funding Number: PAR 11 084 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| New Molecular Entities to Treat Substance Use Disorders (R01) Apply for RFA DA 12 001 Funding Number: RFA DA 12 001 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Exploring Human Induced Pluripotent Stem Cells for Substance Abuse Research (R21) Apply for RFA DA 11 012 Funding Number: RFA DA 11 012 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Personalized Genomics for Symptom Management Bridging the Gaps from Genomic Discovery to Improved Health Outcomes (R01) Apply for RFA NR 11 003 Funding Number: RFA NR 11 003 Agency: National Institutes of Health Category: Education Health Funding Amount: $300,000 |
| Personalized Genomics for Symptom Management Bridging the Gaps from Genomic Discovery to Improved Health Outcomes (R21) Apply for RFA NR 11 004 Funding Number: RFA NR 11 004 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Acute Life Threatening Conditions and Opportunities for Palliative and End of Life Care Research (R01) Apply for RFA NR 11 008 Funding Number: RFA NR 11 008 Agency: National Institutes of Health Category: Education Health Funding Amount: $300,000 |
| Interdisciplinary Approaches for HIV/AIDS Risk Avoidance Decision Making in Developing Adolescents (R01) Apply for RFA NR 11 007 Funding Number: RFA NR 11 007 Agency: National Institutes of Health Category: Education Health Funding Amount: $350,000 |
| Alzheimers Disease Pilot Clinical Trials (R01) Apply for PAR 11 100 Funding Number: PAR 11 100 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| U.S. India Bilateral Brain Research Collaborative Partnerships (U.S. India BRCP) (R21) Apply for PAR 11 099 Funding Number: PAR 11 099 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| Increasing Opportunities in Advanced Heart Failure and Palliative Care Research (R01) Apply for RFA NR 11 006 Funding Number: RFA NR 11 006 Agency: National Institutes of Health Category: Education Health Funding Amount: $300,000 |
| Reducing Health Disparities Among Minority and Underserved Children (R01) Apply for PA 11 104 Funding Number: PA 11 104 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Reducing Health Disparities Among Minority and Underserved Children (R21) Apply for PA 11 105 Funding Number: PA 11 105 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
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