Opportunity Information: Apply for PA 09 108

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Womens Mental Health and Sex/Gender Differences Research (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants.
  • This funding opportunity was created on Feb 20, 2009 and posted on Feb 20, 2009.
  • Applicants must submit their applications by May 7, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: City or township governments Small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments For profit organizations other than small businesses Native American tribal governments (Federally recognized) Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments Public and State controlled institutions of higher education Private institutions of higher education State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments).
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The Womens Mental Health and Sex/Gender Differences Research (R01) opportunity, Funding Opportunity Number PA-09-108, is a National Institutes of Health (NIH) discretionary grant program aimed at advancing research on womens mental health and on how sex and gender differences shape mental health outcomes. The core purpose of the announcement is to encourage institutions and organizations to propose rigorous research projects that deepen scientific understanding of mental health conditions as they affect women, including the biological, psychological, social, and cultural factors that may differ by sex or gender and influence risk, symptom presentation, course of illness, treatment response, and recovery. In practical terms, the FOA is meant to expand the evidence base so that prevention strategies, diagnostics, and interventions can better reflect differences that matter clinically and in public health.

The program uses the NIH Research Project Grant (R01) mechanism, which is NIHs standard funding vehicle for mature, hypothesis-driven research projects with clearly defined aims, strong preliminary rationale, and a detailed approach. The announcement notes that it runs in parallel with another NIH FOA of the same scientific scope, PA-09-109, which uses the R21 exploratory/developmental mechanism. This pairing signals that NIH is supporting both larger, more fully developed projects through the R01 and earlier-stage or higher-risk pilot work through the R21, giving applicants a choice depending on the maturity and scale of their proposed research.

Funding under PA-09-108 is not guaranteed and is explicitly contingent on the availability of appropriated funds as well as the receipt of a sufficient number of scientifically meritorious applications. Like most NIH research announcements, the expected number of awards is not fixed; awards depend on peer review outcomes and program priorities. The program is associated with CFDA 93.242 (Mental Health Research Grants) and does not require cost sharing or matching, which generally means applicants are not expected to contribute non-federal funds as a condition of receiving an award.

Eligibility is broad and includes many types of domestic and non-domestic organizations. Eligible applicants listed include federal, state, county, city, and special district governments; public and private institutions of higher education; independent school districts; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (with exceptions noted for institutions of higher education); small businesses; and other for-profit entities that are not small businesses. The FOA also explicitly includes multiple categories that NIH often highlights to encourage diverse participation, such as Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations. It additionally permits participation by federally recognized tribal governments and other tribal organizations, regional organizations, U.S. territories or possessions, and foreign organizations (non-U.S. entities), reflecting NIHs openness to research capacity across different settings when scientifically justified.

Administratively, the opportunity was posted and created on February 20, 2009, with an original and final closing date of May 7, 2012, and an archive date of June 7, 2012, indicating it is no longer accepting applications. The sponsoring agency is NIH, and the full announcement was hosted on the NIH Grants Guide website. For technical issues accessing the announcement or resolving link problems, the listed point of contact is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

FAQs: Womens Mental Health and Sex/Gender Differences Research (R01) - PA-09-108

What is the PA-09-108 funding opportunity?

PA-09-108 is a National Institutes of Health (NIH) discretionary funding opportunity titled "Womens Mental Health and Sex/Gender Differences Research (R01)." It supports research projects designed to advance understanding of womens mental health and how sex and gender differences influence mental health outcomes.

What is the main purpose of this opportunity?

The purpose is to encourage rigorous research that deepens scientific understanding of mental health conditions as they affect women, including biological, psychological, social, and cultural factors that may differ by sex or gender and influence risk, symptom presentation, illness course, treatment response, and recovery. The goal is to strengthen the evidence base so prevention strategies, diagnostics, and interventions can better reflect clinically and public health-relevant differences.

What grant mechanism does PA-09-108 use?

This opportunity uses the NIH Research Project Grant (R01) mechanism, NIH's standard funding vehicle for mature, hypothesis-driven research projects with clearly defined aims and a detailed research approach.

What kind of projects are a good fit for an R01 under this FOA?

Based on the description provided, projects should be mature and hypothesis-driven, with clearly defined aims, a strong preliminary rationale, and a detailed approach. The scientific focus should relate to womens mental health and/or sex and gender differences that shape mental health outcomes across factors such as risk, symptom presentation, course of illness, treatment response, and recovery.

Is there a related opportunity for exploratory or early-stage projects?

Yes. The announcement states it runs in parallel with PA-09-109, which covers the same scientific scope but uses the R21 exploratory/developmental mechanism. This pairing reflects NIH support for both larger, more fully developed projects (R01) and earlier-stage or higher-risk pilot work (R21).

Is funding guaranteed if an application is submitted?

No. Funding is explicitly contingent on the availability of appropriated funds and on the receipt of a sufficient number of scientifically meritorious applications. The expected number of awards is not fixed and depends on peer review outcomes and program priorities.

Does this opportunity require cost sharing or matching funds?

No. The opportunity states there is no cost sharing or matching requirement, meaning applicants are generally not expected to contribute non-federal funds as a condition of receiving an award.

What CFDA number is associated with this program?

The program is associated with CFDA 93.242 (Mental Health Research Grants).

Who is eligible to apply?

Eligibility is broad and includes many types of domestic and non-domestic organizations. Eligible applicants include federal, state, county, city, and special district governments; public and private institutions of higher education; independent school districts; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (with exceptions noted for institutions of higher education); small businesses; and other for-profit entities that are not small businesses.

Are tribal governments and tribal organizations eligible?

Yes. The eligibility description explicitly permits participation by federally recognized tribal governments and other tribal organizations.

Are U.S. territories or possessions eligible to apply?

Yes. The opportunity includes regional organizations and U.S. territories or possessions among eligible applicant categories.

Are foreign (non-U.S.) organizations eligible to apply?

Yes. The eligibility statement indicates that foreign organizations (non-U.S. entities) are permitted to apply.

Does NIH encourage applications from certain institution types?

Yes. The opportunity explicitly highlights categories NIH often includes to encourage diverse participation, including Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations.

When was PA-09-108 posted, and what were the closing dates?

The opportunity was posted and created on February 20, 2009. The original and final closing date listed is May 7, 2012, and the archive date is June 7, 2012.

Is PA-09-108 still accepting applications?

No. Because the final closing date was May 7, 2012 and the archive date was June 7, 2012, the opportunity is no longer accepting applications.

Who is the sponsoring agency?

The sponsoring agency for this opportunity is the National Institutes of Health (NIH).

Where was the full announcement hosted?

The full announcement was hosted on the NIH Grants Guide website.

Who should be contacted for technical issues accessing the announcement or broken links?

For technical issues accessing the announcement or resolving link problems, the listed point of contact is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

What is the Funding Opportunity Number for this announcement?

The Funding Opportunity Number is PA-09-108.

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