Opportunity Information: Apply for PA 16 316
Apply for PA 16 316
- The HHS-NIH11 in the health, income security and social services sector is offering a public funding opportunity titled "Characterization of the Adolescent Reproductive Transition (R03)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865,.
- This funding opportunity was created on Jun 07, 2016 and posted on Jun 07, 2016.
- Applicants must submit their applications by Sep 07, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $50,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
The Characterization of the Adolescent Reproductive Transition (R03) funding opportunity (PA-16-316) is a National Institutes of Health (NIH) grant program under the U.S. Department of Health and Human Services (HHS) designed to support focused, small-scale research projects that improve scientific understanding of puberty and the overall trajectory of sexual development during adolescence. The central aim is to strengthen the evidence base on what "normative" sexual development looks like in both males and females, and to clarify how reproductive competence becomes established across the pubertal transition. The announcement emphasizes that important knowledge gaps remain in this area and that progress will likely require newer technologies, modern measurement approaches, and innovative study designs that can capture the complexity and timing of developmental change.
In practical terms, this FOA is looking for studies that characterize the adolescent reproductive transition with enough resolution to move beyond broad milestones and toward a more detailed picture of developmental pathways. The intent is to encourage research that can better map the biological and developmental processes of puberty, including how changes unfold over time and how different systems coordinate as adolescents mature. While the opportunity description does not list specific required methods, it clearly signals a preference for applications that bring in fresh tools and approaches capable of generating more precise or informative data than what has traditionally been available. The expectation is that results from these projects will advance the field's foundational understanding of pubertal development and how adolescents reach reproductive maturity.
This is a discretionary grant mechanism using the NIH R03 activity code, which generally supports shorter, more targeted projects such as pilot studies, secondary analyses, early-stage method development, or narrowly scoped investigations that can yield high-value insights without requiring large budgets. The listed award ceiling is $50,000, indicating that proposed work should be tightly focused and achievable within modest direct cost limits. Even with its smaller scale, the program is positioned to fund research that can meaningfully sharpen scientific models of puberty and sexual development, potentially laying groundwork for future, larger studies.
Eligibility is broad and includes many types of organizations that commonly participate in federally funded health research. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations that are not federally recognized governments; public housing authorities and Indian housing authorities; nonprofits with and without 501(c)(3) status (excluding higher education institutions in those nonprofit categories); for-profit organizations other than small businesses; small businesses; and other applicants as described in the FOA's additional eligibility information. This wide eligibility reflects NIH's interest in drawing strong ideas from across academia, government, community-facing organizations, and the private sector when appropriate.
From an administrative standpoint, the opportunity was posted and created on June 7, 2016, and lists an original and current closing date of September 7, 2019. It is associated with CFDA numbers 93.865 (and another number shown but not specified in the provided text), and the sponsoring agency is identified as HHS-NIH11. Overall, the announcement is essentially a call for well-designed, innovation-oriented R03 projects that can deepen understanding of normal pubertal development and the pathways through which adolescents achieve reproductive competence, with the expectation that improved characterization of these processes will strengthen the broader scientific foundation for adolescent reproductive health research.
Frequently Asked Questions (FAQs)
What is the "Characterization of the Adolescent Reproductive Transition (R03)" funding opportunity?
It is an NIH funding opportunity (PA-16-316) under the U.S. Department of Health and Human Services (HHS) designed to support focused, small-scale research projects that improve scientific understanding of puberty and the overall trajectory of sexual development during adolescence.
What is the main purpose of this grant program?
The central purpose is to strengthen the evidence base on what "normative" sexual development looks like in both males and females, and to clarify how reproductive competence becomes established across the pubertal transition.
What kinds of research questions is this FOA trying to address?
It aims to address knowledge gaps in puberty and adolescent sexual development, especially questions that require a more detailed characterization of developmental pathways over time (not just broad milestones) and a clearer picture of how biological and developmental processes coordinate as adolescents mature.
What does the FOA mean by "characterize the adolescent reproductive transition"?
In practical terms, it means studying pubertal development with enough resolution to move beyond coarse markers or milestones and toward a more detailed, time-sensitive mapping of developmental change and the pathways through which adolescents reach reproductive maturity.
Is the focus on males, females, or both?
The description explicitly emphasizes strengthening understanding of normative sexual development in both males and females.
Does the FOA prioritize any particular approach or type of study design?
While no specific methods are listed as required in the provided description, the announcement signals a preference for newer technologies, modern measurement approaches, and innovative study designs that can capture the complexity and timing of developmental change.
Are traditional puberty milestones enough for a competitive application?
The FOA indicates an interest in moving beyond broad milestones, suggesting that applications should aim for more precise, informative, and higher-resolution characterization of pubertal development.
What is the grant mechanism and what does R03 imply?
This opportunity uses the NIH R03 activity code, which generally supports shorter, targeted projects such as pilot studies, secondary analyses, early-stage method development, or narrowly scoped investigations that can produce high-value insights without requiring large budgets.
How much funding is available under this opportunity?
The listed award ceiling is $50,000, indicating that proposed work should be tightly focused and feasible within modest direct cost limits.
Does the FOA expect results that can influence the field even though it is small-scale?
Yes. Even with its smaller scope, the program is positioned to fund research that can meaningfully sharpen scientific models of puberty and sexual development, potentially laying groundwork for future, larger studies.
What types of organizations are eligible to apply?
Eligibility is broad and includes state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations that are not federally recognized governments; public housing authorities and Indian housing authorities; nonprofits with and without 501(c)(3) status (excluding higher education institutions in those nonprofit categories); for-profit organizations other than small businesses; small businesses; and other applicants as described in the FOA's additional eligibility information.
Are higher education institutions eligible?
Yes. Public and state-controlled institutions of higher education, as well as private institutions of higher education, are explicitly included as eligible applicants.
Can government entities apply?
Yes. The eligible applicant list includes state, county, and city or township governments, as well as special district governments.
Can tribal governments or tribal organizations apply?
Yes. Federally recognized Native American tribal governments are eligible, and Native American tribal organizations that are not federally recognized governments are also included as eligible applicants.
Are nonprofits eligible, and does 501(c)(3) status matter?
Nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status are listed as eligible (with the provided text noting an exclusion for higher education institutions in those nonprofit categories).
Are for-profit entities allowed to apply?
Yes. For-profit organizations other than small businesses are included, and small businesses are also listed as eligible.
Who is the sponsoring agency?
The sponsoring agency is the National Institutes of Health (NIH) within the U.S. Department of Health and Human Services (HHS), identified in the provided information as HHS-NIH11.
When was this opportunity posted?
The opportunity was posted and created on June 7, 2016.
What is the closing date for this funding opportunity?
The provided information lists an original and current closing date of September 7, 2019.
What CFDA number(s) are associated with this opportunity?
The opportunity is associated with CFDA number 93.865, and the text also notes another CFDA number is shown but not specified in the provided information.
What outcomes is NIH hoping to see from funded projects?
The expectation described is that results will advance foundational understanding of pubertal development and how adolescents reach reproductive maturity, thereby strengthening the scientific basis for broader adolescent reproductive health research.
Is this FOA intended for large, long-term studies?
Based on the R03 mechanism and the $50,000 award ceiling described, this opportunity is intended for focused, small-scale projects rather than large, long-term studies.
Does this opportunity require a specific method or technology?
The provided description does not specify required methods, but it emphasizes that progress will likely require newer technologies, modern measurement approaches, and innovative designs that better capture the timing and complexity of developmental change.
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